DK1390371T3 - Oxazolo- og furopyrimidiner samt deres anvendelse i lægemidler mod tumorer - Google Patents
Oxazolo- og furopyrimidiner samt deres anvendelse i lægemidler mod tumorerInfo
- Publication number
- DK1390371T3 DK1390371T3 DK02740590T DK02740590T DK1390371T3 DK 1390371 T3 DK1390371 T3 DK 1390371T3 DK 02740590 T DK02740590 T DK 02740590T DK 02740590 T DK02740590 T DK 02740590T DK 1390371 T3 DK1390371 T3 DK 1390371T3
- Authority
- DK
- Denmark
- Prior art keywords
- furopyrimidines
- oxazolo
- well
- tumor drugs
- formula
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229940041181 antineoplastic drug Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH8732001 | 2001-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1390371T3 true DK1390371T3 (da) | 2006-06-19 |
Family
ID=4544205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02740590T DK1390371T3 (da) | 2001-05-14 | 2002-05-13 | Oxazolo- og furopyrimidiner samt deres anvendelse i lægemidler mod tumorer |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7294633B2 (da) |
| EP (1) | EP1390371B1 (da) |
| JP (1) | JP4155827B2 (da) |
| CN (1) | CN100378107C (da) |
| AT (1) | ATE319718T1 (da) |
| BR (1) | BR0209645A (da) |
| CA (1) | CA2449188A1 (da) |
| DE (1) | DE60209721T2 (da) |
| DK (1) | DK1390371T3 (da) |
| ES (1) | ES2259707T3 (da) |
| PT (1) | PT1390371E (da) |
| WO (1) | WO2002092603A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1689753A4 (en) * | 2003-12-04 | 2010-07-07 | Glaxosmithkline Llc | NEW CHEMICAL COMPOUNDS |
| KR20050091462A (ko) * | 2004-03-12 | 2005-09-15 | 한국과학기술연구원 | 푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제 |
| EP1731523A4 (en) * | 2004-04-01 | 2009-08-12 | Takeda Pharmaceutical | THIAZOLOPYRIMIDINDERIVAT |
| CA2605738C (en) | 2005-04-25 | 2013-10-01 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Novel azaheterocyclic compounds as kinase inhibitors |
| DE102005061171A1 (de) | 2005-12-21 | 2007-07-05 | Bayer Healthcare Ag | Neue, cyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung |
| DE102005061170A1 (de) | 2005-12-21 | 2007-07-05 | Bayer Healthcare Ag | Neue, acyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung |
| KR20140043141A (ko) * | 2006-06-22 | 2014-04-08 | 닛뽕 케미파 가부시키가이샤 | 항암제 내성 극복제 |
| DE102007019691A1 (de) | 2007-04-26 | 2008-10-30 | Bayer Healthcare Ag | Verwendung von acyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie |
| DE102007019690A1 (de) * | 2007-04-26 | 2008-10-30 | Bayer Healthcare Ag | Verwendung von cyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie |
| DE102007027799A1 (de) | 2007-06-16 | 2008-12-18 | Bayer Healthcare Ag | Substituierte Furopyrimidine und ihre Verwendung |
| DE102007027800A1 (de) | 2007-06-16 | 2008-12-18 | Bayer Healthcare Ag | Substituierte bicyclische Heteroaryl-Verbindungen und ihre Verwendung |
| RU2345996C1 (ru) * | 2007-07-17 | 2009-02-10 | Андрей Александрович Иващенко | Аннелированные азагетероциклические амиды, включающие пиримидиновый фрагмент, способ их получения и применения |
| US8735387B2 (en) * | 2008-07-15 | 2014-05-27 | Sanofi | Oxazolopyrimidines as Edg-1 receptor agonists |
| UY32240A (es) | 2008-11-14 | 2010-06-30 | Boeringer Ingelheim Kg | Nuevas 2,4-diaminopirimidinas, sus sales farmacéuticamente aceptables, composiciones conteniéndolas y aplicaciones. |
| CN101899057A (zh) * | 2010-07-21 | 2010-12-01 | 中国药科大学 | 嘧啶并噁唑衍生物的一种制备方法及其在医学上的用途 |
| US8580816B2 (en) * | 2011-07-07 | 2013-11-12 | Sanofi | Carboxylic acid derivatives having an oxazolo[5,4-b]pyridine ring |
| US8907093B2 (en) * | 2011-07-07 | 2014-12-09 | Sanofi | Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring |
| CN103087077B (zh) * | 2011-11-03 | 2016-05-18 | 上海希迈医药科技有限公司 | 噻吩并嘧啶和呋喃并嘧啶类衍生物、其制备方法及其在医药上的应用 |
| CN103360407B (zh) * | 2012-04-10 | 2016-06-22 | 上海希迈医药科技有限公司 | 一种噻吩并嘧啶类衍生物、其制备方法及其在医药上的应用 |
| WO2015162518A1 (en) | 2014-04-25 | 2015-10-29 | Pfizer Inc. | Heteroaromatic compounds and their use as dopamine d1 ligands |
| CN104650111A (zh) * | 2015-01-14 | 2015-05-27 | 中国药科大学 | 芳基脲及芳基酰胺取代的噁唑并嘧啶类化合物及其制备和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5137879A (en) | 1990-03-30 | 1992-08-11 | Dowelanco | Furopyrimidin-4-imine derivatives |
| US5227387A (en) * | 1991-09-03 | 1993-07-13 | Dowelanco | Quinoline nematicidal method |
| DK0682027T3 (da) * | 1994-05-03 | 1998-05-04 | Ciba Geigy Ag | Pyrrolopyrimidinderivater med antiproliferativ virkning |
| JPH1184248A (ja) * | 1997-09-12 | 1999-03-26 | Nikon Corp | 反射屈折縮小光学系 |
| WO2002032872A1 (fr) * | 2000-10-20 | 2002-04-25 | Eisai Co., Ltd. | Composes a noyau aromatique azote |
-
2002
- 2002-05-13 JP JP2002589487A patent/JP4155827B2/ja not_active Expired - Fee Related
- 2002-05-13 WO PCT/EP2002/005241 patent/WO2002092603A1/en not_active Ceased
- 2002-05-13 US US10/476,818 patent/US7294633B2/en not_active Expired - Fee Related
- 2002-05-13 DK DK02740590T patent/DK1390371T3/da active
- 2002-05-13 CN CNB028100026A patent/CN100378107C/zh not_active Expired - Fee Related
- 2002-05-13 ES ES02740590T patent/ES2259707T3/es not_active Expired - Lifetime
- 2002-05-13 PT PT02740590T patent/PT1390371E/pt unknown
- 2002-05-13 AT AT02740590T patent/ATE319718T1/de active
- 2002-05-13 EP EP02740590A patent/EP1390371B1/en not_active Expired - Lifetime
- 2002-05-13 CA CA002449188A patent/CA2449188A1/en not_active Abandoned
- 2002-05-13 BR BR0209645-5A patent/BR0209645A/pt not_active IP Right Cessation
- 2002-05-13 DE DE60209721T patent/DE60209721T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1390371E (pt) | 2006-07-31 |
| EP1390371B1 (en) | 2006-03-08 |
| BR0209645A (pt) | 2004-07-06 |
| DE60209721D1 (de) | 2006-05-04 |
| CN100378107C (zh) | 2008-04-02 |
| EP1390371A1 (en) | 2004-02-25 |
| ES2259707T3 (es) | 2006-10-16 |
| CA2449188A1 (en) | 2002-11-21 |
| US7294633B2 (en) | 2007-11-13 |
| ATE319718T1 (de) | 2006-03-15 |
| US20040152892A1 (en) | 2004-08-05 |
| JP4155827B2 (ja) | 2008-09-24 |
| CN1509291A (zh) | 2004-06-30 |
| JP2005508855A (ja) | 2005-04-07 |
| WO2002092603A1 (en) | 2002-11-21 |
| DE60209721T2 (de) | 2006-09-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1390371T3 (da) | Oxazolo- og furopyrimidiner samt deres anvendelse i lægemidler mod tumorer | |
| BG108269A (en) | Pyrazolopyrimidines as therapeutic agents | |
| BG108268A (en) | Pyrazolopyrimidines as therapeutic agents | |
| ATE411022T1 (de) | Pyridylpyrrol-derivate als wirksame kinase-hemmer | |
| CY1107054T1 (el) | Ενωσεις διτοσυλικου αλατος κιναζολινης | |
| DE50310516D1 (de) | Fredericamycin-derivate | |
| ATE452129T1 (de) | N-phenyl-2-pyrimidine-amine derivatives | |
| CY1106476T1 (el) | Υποκατεστημενες διυδροκιναζολινες με αντι-ιικες ιδιοτητες | |
| CY1108129T1 (el) | Παραγωγα 4-αμινο-6-φαινυλ-πυρρολο[2,3-δ]πυριμιδινης | |
| TR200201505T2 (tr) | Terapötik maddeler olarak pirazolopirimidinler | |
| TW200635923A (en) | Tricyclic heterocycles, their manufacture and use as pharmaceutical agents | |
| EA200501849A1 (ru) | Производные пиразолохиназолина: способ получения и применение в качестве ингибиторов киназ | |
| CY1110247T1 (el) | Παραγωγα βενζοκιναζολινης και η χρηση τους στην θεραπεια των διαταραχων των οστων | |
| DE602004024375D1 (de) | Carboxamidderivate | |
| BRPI0508700A (pt) | uso de sns-595, composição farmacêutica, e, pó liofilizado | |
| WO2004108715A8 (en) | 3-aryloxy and 3-heteroaryloxy substituted benzo(b) thiophenes as therapeutic agents with pi3k activity | |
| MXPA04001256A (es) | Productos de combinacion de derivados de propanolamina aril substituidos con otros ingredientes activos y su uso. | |
| SE0401342D0 (sv) | Therapeutic compounds | |
| EP1643984A4 (en) | USE OF PARTHENOLID DERIVATIVES AS ANTILEUKEMIC AND CYTOTOXIC AGENTS | |
| MXPA05012953A (es) | Benzo[b]tiofenos 3-arilsulfanil y 3-heteroarilsulfanil sustituidos como agentes terapeuticos. | |
| EA200501310A1 (ru) | Производные бензолсульфонамидов, способ их получения и их применение для лечения боли | |
| ECSP055844A (es) | Nuevos compuestos triciclicos | |
| DK1558620T3 (da) | Rutheniumkomplekser med anticancervirkning | |
| NO20013414D0 (no) | Ny anvendelse av melagatran | |
| TW200504051A (en) | Novel acridine derivatives and their use as medicaments |