DK1381681T3 - NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelser - Google Patents

NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelser

Info

Publication number: DK1381681T3
Authority: DK; Denmark
Prior art keywords: variants; hgf; fragment; applications; growth factor
Prior art date: 2001-04-27

Application number

DK02720271T

Other languages

Danish (da)

English (en)

Inventor

Ermanno Gherardi

Daniel Lietha

Thomas Leon Blundell

Dimitry Yurievich Chirgadze

Original Assignee

Medical Res Council

Cambridge Entpr Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-27

Filing date

2002-04-29

Publication date

2007-10-29

2002-04-29 Application filed by Medical Res Council, Cambridge Entpr Ltd filed Critical Medical Res Council

2007-10-29 Application granted granted Critical

2007-10-29 Publication of DK1381681T3 publication Critical patent/DK1381681T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Zoology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Virology (AREA)
Cardiology (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Dermatology (AREA)

DK02720271T 2001-04-27 2002-04-29 NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelser DK1381681T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0110430.6A GB0110430D0 (en)	2001-04-27	2001-04-27	Protein variants and uses thereof
PCT/GB2002/001941 WO2002088354A1 (fr)	2001-04-27	2002-04-29	Fragment nk1 du facteur de croissance/facteur de diffusion d'epatocyte (hgf/sf) et ses variants, ainsi que leur utilisation

Publications (1)

Publication Number	Publication Date
DK1381681T3 true DK1381681T3 (da)	2007-10-29

Family

ID=9913640

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02720271T DK1381681T3 (da)	2001-04-27	2002-04-29	NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelser

Country Status (11)

Country	Link
US (3)	US7179786B2 (fr)
EP (1)	EP1381681B1 (fr)
JP (2)	JP4637452B2 (fr)
AT (1)	ATE368741T1 (fr)
AU (1)	AU2002251337B2 (fr)
CA (1)	CA2440775C (fr)
DE (1)	DE60221510T2 (fr)
DK (1)	DK1381681T3 (fr)
ES (1)	ES2291460T3 (fr)
GB (1)	GB0110430D0 (fr)
WO (1)	WO2002088354A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0110430D0 (en) *	2001-04-27	2001-06-20	Medical Res Council	Protein variants and uses thereof
US20050107296A1 (en) *	2001-10-31	2005-05-19	Institut Des Vaisseaux Et Du Sang	Isolated peptide of the hepatocyte growth factor and its variants, preparation method and therapeutic use as anti-angiogenic agents
AT412785B (de) *	2003-12-04	2005-07-25	Kungl Andreas J Dr	Gag-bindungsproteine
US7563570B2 (en)	2004-10-29	2009-07-21	Pangaea Biotech	Method of determining a chemotherapeutic regimen for non small cell lung cancer based on BRCA1 expression
US20090215686A1 (en) *	2007-03-05	2009-08-27	Huaqiang Eric Xu	Nk1-based polypeptides and related methods
CA2743184A1 (fr) *	2007-11-09	2009-05-14	New York Medical College	Procedes et compositions pour la reparation et/ou la regeneration de myocarde endommage mettant en uvre des cytokines et leurs variants
CN103037892A (zh) *	2010-02-22	2013-04-10	布里格姆妇女医院	诱导血管生成的组合物和方法
WO2011116396A2 (fr) *	2010-03-19	2011-09-22	The Board Of Trustees Of The Leland Stanford Junior University	Fragments de facteur de croissance d'hépatocyte qui fonctionnent comme agonistes et antagonistes du récepteur met puissant
EP3604549A1 (fr)	2010-11-08	2020-02-05	The Board of Trustees of the Leland Stanford Junior University	Protéines de fusion comprenant un peptide knottine modifié et leurs utilisations
WO2013037521A1 (fr)	2011-09-16	2013-03-21	Medical Research Council	Polypeptide hgf-1k1 modifié
WO2013037520A1 (fr)	2011-09-16	2013-03-21	Glaxo Group Limited	Polypeptide hgf-1k1 modifié
US10435450B2 (en)	2015-01-21	2019-10-08	Centre National De La Recherche Scientifique	MET receptor agonist proteins
IL303455A (en)	2016-06-17	2023-08-01	Crispr Therapeutics Ag	Compositions and methods for the depletion of cd117+cells
GB201611123D0 (en)	2016-06-27	2016-08-10	Euremab Srl	Anti met antibodiesand uses thereof
JP7256744B2 (ja)	2017-01-20	2023-04-12	マジェンタセラピューティクスインコーポレイテッド	Ｃｄ１３７＋細胞の枯渇のための組成物および方法
IT201800000535A1 (it)	2018-01-03	2019-07-03		Procedimenti per la cura del cancro.
CN109535243B (zh) *	2019-01-07	2019-09-24	北京诺思兰德生物技术股份有限公司	人肝细胞生长因子突变体及其应用
CN119613527A (zh) *	2024-12-30	2025-03-14	江苏三仪生物工程有限公司	鸡肝细胞生长因子的截短突变体及其在防治肝脏相关疾病方面的用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5594115A (en) *	1990-04-09	1997-01-14	Pharmacia & Upjohn Company	Process of purifying recombinant proteins and compounds useful in such process
US6566098B1 (en)	1990-09-14	2003-05-20	The United States Of America As Represented By The Department Of Health And Human Services	DNA encoding truncated hepatocyte growth factor variants
ES2181689T3 (es)	1992-05-18	2003-03-01	Genentech Inc	Variantes del factor de crecimiento de hepatocitos.
JP4006058B2 (ja) *	1997-03-11	2007-11-14	第一三共株式会社	多臓器不全予防及び／又は治療剤
GB0110430D0 (en) *	2001-04-27	2001-06-20	Medical Res Council	Protein variants and uses thereof

2001
- 2001-04-27 GB GBGB0110430.6A patent/GB0110430D0/en not_active Ceased
2002
- 2002-04-29 DE DE60221510T patent/DE60221510T2/de not_active Expired - Lifetime
- 2002-04-29 WO PCT/GB2002/001941 patent/WO2002088354A1/fr not_active Ceased
- 2002-04-29 DK DK02720271T patent/DK1381681T3/da active
- 2002-04-29 US US10/475,616 patent/US7179786B2/en not_active Expired - Fee Related
- 2002-04-29 ES ES02720271T patent/ES2291460T3/es not_active Expired - Lifetime
- 2002-04-29 JP JP2002585635A patent/JP4637452B2/ja not_active Expired - Fee Related
- 2002-04-29 AU AU2002251337A patent/AU2002251337B2/en not_active Ceased
- 2002-04-29 AT AT02720271T patent/ATE368741T1/de not_active IP Right Cessation
- 2002-04-29 CA CA2440775A patent/CA2440775C/fr not_active Expired - Fee Related
- 2002-04-29 EP EP02720271A patent/EP1381681B1/fr not_active Expired - Lifetime
2007
- 2007-01-26 US US11/627,761 patent/US7795214B2/en not_active Expired - Fee Related
2010
- 2010-08-17 US US12/858,189 patent/US8232258B2/en not_active Expired - Fee Related
- 2010-09-17 JP JP2010208693A patent/JP2011045370A/ja active Pending

Also Published As

Publication number	Publication date
GB0110430D0 (en)	2001-06-20
US8232258B2 (en)	2012-07-31
US20040236073A1 (en)	2004-11-25
JP2004532032A (ja)	2004-10-21
DE60221510T2 (de)	2008-04-17
US20080167224A1 (en)	2008-07-10
WO2002088354A1 (fr)	2002-11-07
US7795214B2 (en)	2010-09-14
CA2440775C (fr)	2013-02-26
US7179786B2 (en)	2007-02-20
ES2291460T3 (es)	2008-03-01
ATE368741T1 (de)	2007-08-15
EP1381681B1 (fr)	2007-08-01
DE60221510D1 (de)	2007-09-13
AU2002251337B2 (en)	2007-08-02
JP2011045370A (ja)	2011-03-10
EP1381681A1 (fr)	2004-01-21
CA2440775A1 (fr)	2002-11-07
US20110021612A1 (en)	2011-01-27
JP4637452B2 (ja)	2011-02-23

Publication	Publication Date	Title
DK1381681T3 (da)	2007-10-29	NK1-fragmentet af hepatocytvækstfaktor/spredningsfaktor (HGF/SF) og varianter deraf og deres anvendelser
DK1390066T3 (da)	2012-07-16	Vaccinesammensætning
FI20010780A0 (fi)	2001-04-12	Parannetut koostumukset
ATE319666T1 (de)	2006-03-15	Gipszusammensetzung mit verbesserter deformationsstabilität
NO20025450L (no)	2002-11-14	Ny farmasöytisk sammensetning
PL367180A1 (pl)	2005-02-21	Trwała kompozycja farmaceutyczna
PL375874A1 (pl)	2005-12-12	Wodne kompozycje farmaceutyczne 2,6-diizopropylofenolu
IS7081A (is)	2003-12-16	Lyfjablanda
EE200300589A (et)	2004-02-16	Ravimkoostised
DE69931821D1 (de)	2006-07-20	Wärmehärtbare pulverlack-zusammensetzung
EE200200281A (et)	2003-06-16	Pikornaviirusevastased ühendid ja kompositsioonid, nende farmatseutilised kasutusalad ning ained nende sünteesiks
FI20022128A0 (fi)	2002-12-03	Farmaseuttinen koostumus
NO20040860L (no)	2004-04-22	Farmasoytisk sammensetning som innbefatter lumiracoxib
NO20034556D0 (no)	2003-10-10	Imidazotriazinon-holdige sammensetninger for nasal administrering
DE60036959D1 (de)	2007-12-13	Tensidzusammensetzungen, verbesserungsmittel enthaltend
DE10290726D2 (de)	2004-04-15	Strebsteuerung für den Strebausbau
DE50114951D1 (de)	2009-08-06	Stabilisatorzusammensetzung
SE9904404L (sv)	2000-12-23	Ny komposition
NO20014586D0 (no)	2001-09-21	Resorcinol sammensetninger
DE60005826D1 (de)	2003-11-13	Fungizide zusammensetzungen
FR2783401B1 (fr)	2000-10-20	Nouvelles compositions fongicides
NO20033073D0 (no)	2003-07-04	Farmasöytisk sammensetning inneholdende citalopram
DE60140529D1 (de)	2009-12-31	Feuerlöschende Zusammensetzung
ATE549920T1 (de)	2012-04-15	Insektizide zusammensetzung
NO20022844D0 (no)	2002-06-14	N-(1-fenyletyl)-5-fenyl-imidazol-2-aminforbindelser, deres sammensetninger og anvendelser