DK1289368T3 - Fremgangsmåde til fremstilling af herpes simplex virus ampliconer, deraf resulterende amplicober samt deres anvendelse - Google Patents
Fremgangsmåde til fremstilling af herpes simplex virus ampliconer, deraf resulterende amplicober samt deres anvendelseInfo
- Publication number
- DK1289368T3 DK1289368T3 DK01939333.9T DK01939333T DK1289368T3 DK 1289368 T3 DK1289368 T3 DK 1289368T3 DK 01939333 T DK01939333 T DK 01939333T DK 1289368 T3 DK1289368 T3 DK 1289368T3
- Authority
- DK
- Denmark
- Prior art keywords
- hsv
- amplicon particles
- herpes simplex
- simplex virus
- amplicon
- Prior art date
Links
- 241000700584 Simplexvirus Species 0.000 title abstract 10
- 108091093088 Amplicon Proteins 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 2
- 239000002245 particle Substances 0.000 abstract 5
- 108700019146 Transgenes Proteins 0.000 abstract 2
- 238000003776 cleavage reaction Methods 0.000 abstract 2
- 238000004806 packaging method and process Methods 0.000 abstract 2
- 230000007017 scission Effects 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 101710165490 Virion host shutoff protein Proteins 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20649700P | 2000-05-23 | 2000-05-23 | |
| PCT/US2001/016682 WO2001089304A1 (en) | 2000-05-23 | 2001-05-23 | Method of producing herpes simplex virus amplicons, resulting amplicons, and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1289368T3 true DK1289368T3 (da) | 2010-05-03 |
Family
ID=22766659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01939333.9T DK1289368T3 (da) | 2000-05-23 | 2001-05-23 | Fremgangsmåde til fremstilling af herpes simplex virus ampliconer, deraf resulterende amplicober samt deres anvendelse |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1289368B1 (da) |
| AT (1) | ATE454039T1 (da) |
| AU (2) | AU2001264862B2 (da) |
| CA (1) | CA2410536A1 (da) |
| DE (1) | DE60141014D1 (da) |
| DK (1) | DK1289368T3 (da) |
| WO (1) | WO2001089304A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE466078T1 (de) | 2000-11-29 | 2010-05-15 | Univ Rochester | Helfervirus-freie herpesvirus-amplifikatpartikel und deren verwendungen |
| US8092791B2 (en) | 2001-05-23 | 2012-01-10 | University Of Rochester | Method of producing herpes simplex virus amplicons, resulting amplicons, and their use |
| EP1532254A4 (en) * | 2002-05-31 | 2006-05-10 | Univ Rochester | VIRUS-FREE HELPER HERPESVIRUS AMPLICON PARTICLES AND ITS USES |
| US7399851B2 (en) | 2002-07-25 | 2008-07-15 | Dana Farber Cancer Institute, Inc. | Composition and method for imaging cells |
| CA2513559A1 (en) * | 2003-01-23 | 2004-08-05 | University Of Rochester | Herpesvirus amplicon particles |
| ES2368741T3 (es) | 2004-02-25 | 2011-11-21 | Dana-Farber Cancer Institute, Inc. | Inhibidores del receptor 1 del factor de crecimiento de tipo insulina para inhibir el crecimiento de células tumorales. |
| US7968762B2 (en) | 2004-07-13 | 2011-06-28 | Van Andel Research Institute | Immune-compromised transgenic mice expressing human hepatocyte growth factor (hHGF) |
| AU2006258099A1 (en) * | 2005-06-03 | 2006-12-21 | University Of Rochester | Herpes virus-based compositions and methods of use in the prenatal and perinatal periods |
| EP2032173A4 (en) * | 2006-06-06 | 2011-03-30 | Univ Rochester | HELPFREE-FREE HERPESVIRUS AMPLICON PARTICLES AND ITS USE |
| US20080199475A1 (en) | 2006-11-27 | 2008-08-21 | Patrys Limited | Novel glycosylated peptide target in neoplastic cells |
| MX2010001307A (es) | 2007-08-02 | 2010-07-30 | Novimmune Sa | Anticuerpos anti-proteína regulada con la activación, expresada y secretada por los linfocitos t normales y metodos de uso de los mismos. |
| WO2010054221A2 (en) | 2008-11-06 | 2010-05-14 | The Johns Hopkins University | Treatment of chronic inflammatory respiratory disorders |
| EP2258858A1 (en) | 2009-06-05 | 2010-12-08 | Universitätsklinikum Freiburg | Transgenic LSD1 animal model for cancer |
| EP2509628B1 (en) | 2009-12-07 | 2017-10-25 | The Johns Hopkins University | Sr-bi as a predictor of human female infertility and responsiveness to treatment |
| CN116333057A (zh) | 2016-05-13 | 2023-06-27 | 4D分子治疗有限公司 | 腺相关病毒变体衣壳和其使用方法 |
| IL273261B2 (en) | 2017-09-20 | 2025-04-01 | 4D Molecular Therapeutics Inc | Adeno-associated virus variant capsids and methods of using them |
| JP7184894B2 (ja) | 2017-11-27 | 2022-12-06 | ４ディー モレキュラー セラピューティクス インコーポレイテッド | アデノ随伴ウイルス変異キャプシドおよび血管新生の阻害のための使用 |
| AU2022281825A1 (en) | 2021-05-28 | 2024-01-18 | Shanghai Regenelead Therapies Co., Ltd. | Recombinant adeno-associated virus having variant capsid, and application thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0448650A4 (en) * | 1989-02-01 | 1992-05-13 | The General Hospital Corporation | Herpes simplex virus type i expression vector |
-
2001
- 2001-05-23 DK DK01939333.9T patent/DK1289368T3/da active
- 2001-05-23 CA CA002410536A patent/CA2410536A1/en not_active Abandoned
- 2001-05-23 WO PCT/US2001/016682 patent/WO2001089304A1/en not_active Ceased
- 2001-05-23 AT AT01939333T patent/ATE454039T1/de not_active IP Right Cessation
- 2001-05-23 AU AU2001264862A patent/AU2001264862B2/en not_active Ceased
- 2001-05-23 DE DE60141014T patent/DE60141014D1/de not_active Expired - Lifetime
- 2001-05-23 EP EP01939333A patent/EP1289368B1/en not_active Expired - Lifetime
- 2001-05-23 AU AU6486201A patent/AU6486201A/xx active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE454039T1 (de) | 2010-01-15 |
| WO2001089304A1 (en) | 2001-11-29 |
| DE60141014D1 (de) | 2010-02-25 |
| EP1289368B1 (en) | 2010-01-06 |
| CA2410536A1 (en) | 2001-11-29 |
| EP1289368A1 (en) | 2003-03-12 |
| AU6486201A (en) | 2001-12-03 |
| EP1289368A4 (en) | 2006-04-19 |
| AU2001264862B2 (en) | 2006-03-30 |
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