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DK1280784T3 - Biologisk aktive 4H-benzo[1,4]oxazin-3-oner - Google Patents

Biologisk aktive 4H-benzo[1,4]oxazin-3-oner

Info

Publication number
DK1280784T3
DK1280784T3 DK01937335T DK01937335T DK1280784T3 DK 1280784 T3 DK1280784 T3 DK 1280784T3 DK 01937335 T DK01937335 T DK 01937335T DK 01937335 T DK01937335 T DK 01937335T DK 1280784 T3 DK1280784 T3 DK 1280784T3
Authority
DK
Denmark
Prior art keywords
oxazin
benzo
ones
biologically active
biologically
Prior art date
Application number
DK01937335T
Other languages
English (en)
Inventor
Thomas P Burris
Donald W Combs
Philip J Rybczynski
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1280784T3 publication Critical patent/DK1280784T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533Six-membered rings
    • C07F9/65335Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK01937335T 2000-05-12 2001-05-11 Biologisk aktive 4H-benzo[1,4]oxazin-3-oner DK1280784T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20386000P 2000-05-12 2000-05-12
PCT/US2001/015383 WO2001087862A2 (en) 2000-05-12 2001-05-11 Biologically active 4h-benzo[1,4]oxazin-3-ones
US09/854,302 US6555536B2 (en) 2000-05-12 2001-05-11 Biologically active 4H-benzo [1,4]oxazin-3-ones

Publications (1)

Publication Number Publication Date
DK1280784T3 true DK1280784T3 (da) 2007-10-29

Family

ID=26898967

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01937335T DK1280784T3 (da) 2000-05-12 2001-05-11 Biologisk aktive 4H-benzo[1,4]oxazin-3-oner

Country Status (12)

Country Link
US (1) US6555536B2 (da)
EP (1) EP1280784B1 (da)
AR (1) AR033375A1 (da)
AT (1) ATE365725T1 (da)
AU (1) AU2001263083A1 (da)
CY (1) CY1106863T1 (da)
DE (1) DE60129123T2 (da)
DK (1) DK1280784T3 (da)
ES (1) ES2288957T3 (da)
MY (1) MY141659A (da)
PT (1) PT1280784E (da)
WO (1) WO2001087862A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7041691B1 (en) 1999-06-30 2006-05-09 Amgen Inc. Compounds for the modulation of PPARγ activity
US6908908B2 (en) * 2000-05-12 2005-06-21 Ortho-Mcneil Pharmaceutical, Inc. Biologically active 4H-benzo [1,4] oxazin-3-ones
US20030171399A1 (en) 2000-06-28 2003-09-11 Tularik Inc. Quinolinyl and benzothiazolyl modulators
IL159320A0 (en) * 2001-06-12 2004-06-01 Wellstat Therapeutics Corp Compounds for the treatment of metabolic disorders
US7041693B2 (en) 2002-10-04 2006-05-09 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
US7223761B2 (en) 2003-10-03 2007-05-29 Amgen Inc. Salts and polymorphs of a potent antidiabetic compound
US20080051418A1 (en) * 2004-11-26 2008-02-28 Tsuyoshi Maekawa Arylalkanoic Acid Derivative
CA2642662A1 (en) * 2006-02-28 2007-09-07 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
AU2007292883B2 (en) 2006-09-08 2013-09-05 Rhode Island Hospital Treatment, prevention, and reversal of alcohol-induced brain disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents
WO1996004261A1 (en) 1994-07-29 1996-02-15 Smithkline Beecham Plc Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes
JPH0912575A (ja) * 1995-06-28 1997-01-14 Sankyo Co Ltd ベンゾオキサジンおよびベンゾチアジン誘導体
US5696117A (en) * 1995-11-07 1997-12-09 Ortho Pharmaceutical Corporation Benzoxazine antimicrobial agents
US5707990A (en) * 1996-01-30 1998-01-13 Ortho Pharmaceutical Corporation 2-substituted amino and thio alkyl benzoxazine antimicrobial agents
NZ504106A (en) * 1998-05-27 2003-02-28 Dr Fused Oxazine, Thiazine and pipyridine compounds, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PT1280784E (pt) 2007-09-03
US20020165228A1 (en) 2002-11-07
DE60129123T2 (de) 2008-02-28
ES2288957T3 (es) 2008-02-01
US6555536B2 (en) 2003-04-29
AU2001263083A1 (en) 2001-11-26
EP1280784A2 (en) 2003-02-05
EP1280784B1 (en) 2007-06-27
CY1106863T1 (el) 2012-09-26
WO2001087862A2 (en) 2001-11-22
AR033375A1 (es) 2003-12-17
DE60129123D1 (de) 2007-08-09
MY141659A (en) 2010-05-31
ATE365725T1 (de) 2007-07-15
WO2001087862A3 (en) 2002-05-30

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