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DK1242439T3 - Process for Preparation and Isolation of 9-Deoxo-9 (Z) -hydroxyiminoerythromycin A - Google Patents

Process for Preparation and Isolation of 9-Deoxo-9 (Z) -hydroxyiminoerythromycin A

Info

Publication number
DK1242439T3
DK1242439T3 DK00990066T DK00990066T DK1242439T3 DK 1242439 T3 DK1242439 T3 DK 1242439T3 DK 00990066 T DK00990066 T DK 00990066T DK 00990066 T DK00990066 T DK 00990066T DK 1242439 T3 DK1242439 T3 DK 1242439T3
Authority
DK
Denmark
Prior art keywords
hydroxyiminoerythromycin
deoxo
isolation
preparation
Prior art date
Application number
DK00990066T
Other languages
Danish (da)
Inventor
Thierry Durand
Patrick Leon
Francois Basset
Ronan Guevel
Frederic Lhermitte
Gilles Oddon
Denis Pauze
Original Assignee
Merial Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Sas filed Critical Merial Sas
Application granted granted Critical
Publication of DK1242439T3 publication Critical patent/DK1242439T3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK00990066T 1999-12-20 2000-12-19 Process for Preparation and Isolation of 9-Deoxo-9 (Z) -hydroxyiminoerythromycin A DK1242439T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9916106A FR2802534B1 (en) 1999-12-20 1999-12-20 PROCESS FOR PREPARING AND ISOLATING 9-DEOXO-9 (Z) - HYDROXYIMINOERYTHROMYCIN A
PCT/FR2000/003595 WO2001046211A1 (en) 1999-12-20 2000-12-19 Method for preparing and isolating 9-deoxo-9(z)-hydroxyiminoerythromycin a

Publications (1)

Publication Number Publication Date
DK1242439T3 true DK1242439T3 (en) 2003-09-15

Family

ID=9553516

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00990066T DK1242439T3 (en) 1999-12-20 2000-12-19 Process for Preparation and Isolation of 9-Deoxo-9 (Z) -hydroxyiminoerythromycin A

Country Status (18)

Country Link
EP (1) EP1242439B1 (en)
JP (1) JP2003518133A (en)
CN (1) CN1215077C (en)
AR (1) AR027021A1 (en)
AT (1) ATE240967T1 (en)
AU (1) AU776674B2 (en)
BR (1) BRPI0016506B8 (en)
CA (1) CA2394623C (en)
DE (1) DE60002922T2 (en)
DK (1) DK1242439T3 (en)
ES (1) ES2202215T3 (en)
FR (1) FR2802534B1 (en)
NZ (1) NZ519802A (en)
PL (2) PL201837B1 (en)
PT (1) PT1242439E (en)
TR (1) TR200300174T3 (en)
WO (1) WO2001046211A1 (en)
ZA (1) ZA200205697B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103713080A (en) * 2013-12-25 2014-04-09 挑战(天津)动物药业有限公司 Method for detecting content of gamithromycin
CN105461770B (en) * 2015-12-25 2018-11-06 湖北回盛生物科技有限公司 A kind of synthetic method of 9- deoxidations -9- homoerythromycins A (Z) oxime
CN115724896A (en) * 2022-11-18 2023-03-03 枣庄市润安制药新材料有限公司 Synthesis method of E/Z type erythromycin A oxime with two configurations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
EP0503932B1 (en) * 1991-03-15 1998-12-02 Merck & Co. Inc. 9-Deoxo-9(z)-hydroxy-iminoerythromycin A and O-derivatives thereof
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
US5808017A (en) * 1996-04-10 1998-09-15 Abbott Laboratories Process for preparing erythromycin A oxime
US5945405A (en) * 1997-01-17 1999-08-31 Abbott Laboratories Crystal form O of clarithromycin
JP2001506281A (en) * 1997-07-08 2001-05-15 バイオケミ・エセ・ア Erythromycin A oxime solvate

Also Published As

Publication number Publication date
FR2802534B1 (en) 2002-02-01
AR027021A1 (en) 2003-03-12
PT1242439E (en) 2003-10-31
BRPI0016506B8 (en) 2021-05-25
DE60002922T2 (en) 2004-05-19
WO2001046211A1 (en) 2001-06-28
ZA200205697B (en) 2003-09-29
AU2687001A (en) 2001-07-03
NZ519802A (en) 2005-03-24
BR0016506A (en) 2002-08-27
CA2394623C (en) 2012-07-24
PL355573A1 (en) 2004-05-04
ES2202215T3 (en) 2004-04-01
DE60002922D1 (en) 2003-06-26
EP1242439B1 (en) 2003-05-21
AU776674B2 (en) 2004-09-16
ATE240967T1 (en) 2003-06-15
CA2394623A1 (en) 2001-06-28
CN1215077C (en) 2005-08-17
EP1242439A1 (en) 2002-09-25
PL201837B1 (en) 2009-05-29
JP2003518133A (en) 2003-06-03
BR0016506B1 (en) 2013-11-26
FR2802534A1 (en) 2001-06-22
CN1411465A (en) 2003-04-16
TR200300174T3 (en) 2003-07-21
PL200527B1 (en) 2009-01-30

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