DK1240186T3 - Forbedringer i eller relateret til immunrespons mod HIV - Google Patents
Forbedringer i eller relateret til immunrespons mod HIVInfo
- Publication number
- DK1240186T3 DK1240186T3 DK00985690.7T DK00985690T DK1240186T3 DK 1240186 T3 DK1240186 T3 DK 1240186T3 DK 00985690 T DK00985690 T DK 00985690T DK 1240186 T3 DK1240186 T3 DK 1240186T3
- Authority
- DK
- Denmark
- Prior art keywords
- hiv
- immune response
- immunogen
- synthetic polypeptide
- protein
- Prior art date
Links
- 230000028993 immune response Effects 0.000 title abstract 2
- 101710177291 Gag polyprotein Proteins 0.000 abstract 2
- 101710125418 Major capsid protein Proteins 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108091035707 Consensus sequence Proteins 0.000 abstract 1
- 108010048209 Human Immunodeficiency Virus Proteins Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- AIDS & HIV (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9930294.5A GB9930294D0 (en) | 1999-12-23 | 1999-12-23 | Improvements in or relating to immune responses to HIV |
| GB0025234A GB0025234D0 (en) | 2000-10-14 | 2000-10-14 | Improvements in or relating to immune responses to HIV |
| PCT/GB2000/004984 WO2001047955A2 (en) | 1999-12-23 | 2000-12-22 | Improvements in or relating to immune responses to hiv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1240186T3 true DK1240186T3 (da) | 2010-05-31 |
Family
ID=26245157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00985690.7T DK1240186T3 (da) | 1999-12-23 | 2000-12-22 | Forbedringer i eller relateret til immunrespons mod HIV |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7993651B2 (da) |
| EP (1) | EP1240186B1 (da) |
| JP (1) | JP4805511B2 (da) |
| CN (1) | CN1213068C (da) |
| AT (1) | ATE457996T1 (da) |
| AU (1) | AU784679B2 (da) |
| BR (1) | BR0016510A (da) |
| CA (1) | CA2392877C (da) |
| CY (1) | CY1110917T1 (da) |
| DE (1) | DE60043856D1 (da) |
| DK (1) | DK1240186T3 (da) |
| ES (1) | ES2341429T3 (da) |
| MX (1) | MXPA02006379A (da) |
| PT (1) | PT1240186E (da) |
| WO (1) | WO2001047955A2 (da) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2360347C (en) | 1998-12-31 | 2013-05-07 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| JP2003523721A (ja) | 1998-12-31 | 2003-08-12 | カイロン コーポレイション | 抗原性hivc型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用 |
| US8623379B2 (en) | 2000-03-02 | 2014-01-07 | Emory University | Compositions and methods for generating an immune response |
| AU2002211948B2 (en) | 2000-03-02 | 2007-09-13 | Emory University | DNA expression vectors and methods of use |
| EP1372710B1 (en) | 2001-03-08 | 2009-10-14 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Mva expressing modified hiv envelope, gag, and pol genes |
| AU2002320314A1 (en) | 2001-07-05 | 2003-01-21 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| JP4601956B2 (ja) * | 2001-09-20 | 2010-12-22 | グラクソ グループ リミテッド | Hiv−gagのコドン最適化dnaワクチン |
| GB0225788D0 (en) | 2002-11-05 | 2002-12-11 | Glaxo Group Ltd | Vaccine |
| ATE520708T1 (de) * | 2003-03-28 | 2011-09-15 | Us Gov Health & Human Serv | Immunogenetische hiv-1 multi-klade, multivalente konstrukte und deren verwendung |
| WO2005034992A2 (en) * | 2003-09-15 | 2005-04-21 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Hiv vaccines based on env of multiple clades of hif |
| WO2005030964A1 (en) * | 2003-09-24 | 2005-04-07 | Oxxon Therapeutics Limited | Hiv pharmaccines |
| WO2005047483A2 (en) | 2003-11-12 | 2005-05-26 | Medical Research Council | Renta: an hiv immunogen and uses thereof |
| TW200613554A (en) | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
| JP4772045B2 (ja) * | 2004-07-16 | 2011-09-14 | アメリカ合衆国 | Cmv/r核酸コンストラクトを含むaidsに対するワクチン |
| GB0417494D0 (en) * | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| JP5122983B2 (ja) | 2005-02-24 | 2013-01-16 | メディカル リサーチ カウンシル | Hivcon:hiv免疫原及びその使用 |
| AU2007256717B2 (en) * | 2006-06-02 | 2013-06-20 | International Aids Vaccine Initiative | HIV-1 Clade A consensus sequences, antigens, and transgenes |
| WO2010096561A1 (en) * | 2009-02-18 | 2010-08-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Synthetic hiv/siv gag proteins and uses thereof |
| US20120135032A1 (en) | 2009-10-08 | 2012-05-31 | Bavarian Nordic A/S | Generation of a broad t-cell response in humans against hiv |
| EP2550362B1 (en) | 2010-03-25 | 2017-01-04 | Oregon Health&Science University | Cmv glycoproteins and recombinant vectors |
| CA2817418A1 (en) * | 2010-11-10 | 2012-05-18 | Laboratorios Del Dr. Esteve, S.A. | Highly immunogenic hiv p24 sequences |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| EP2620446A1 (en) * | 2012-01-27 | 2013-07-31 | Laboratorios Del Dr. Esteve, S.A. | Immunogens for HIV vaccination |
| US9347065B2 (en) | 2012-03-29 | 2016-05-24 | International Aids Vaccine Initiative | Methods to improve vector expression and genetic stability |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| WO2014040025A2 (en) | 2012-09-10 | 2014-03-13 | International Aids Vaccine Initiative | Immunogens of hiv-1 broadly neutralizing antibodies, methods of generation and uses thereof |
| EP2745845A1 (en) | 2012-12-19 | 2014-06-25 | Centre Hospitalier Universitaire de Bordeaux | A method for preventing or treating an HIV infection |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US20170174734A1 (en) * | 2014-03-12 | 2017-06-22 | Temple University-Of The Commonwealth System Of Higher Education | DR6 Receptor Mediates the Leukemia Differentiation Activity of Angiocidin: A Potent Anti-Tumor Peptide |
| US10093720B2 (en) | 2014-06-11 | 2018-10-09 | International Aids Vaccine Initiative | Broadly neutralizing antibody and uses thereof |
| EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US9925258B2 (en) | 2015-10-02 | 2018-03-27 | International Aids Vaccine Initiative | Replication-competent VSV-HIV Env vaccines |
| CN109414597A (zh) | 2016-03-09 | 2019-03-01 | 马萨诸塞大学 | 经修饰的hiv-1用于产生完全人抗体的用途 |
| CA3145833A1 (en) * | 2019-07-02 | 2021-01-07 | Roman YELENSKY | Hiv antigens and mhc complexes |
| AU2020384323A1 (en) | 2019-11-14 | 2022-06-02 | Aelix Therapeutics, S.L. | Dosage regimens for vaccines |
| WO2021185851A1 (en) | 2020-03-17 | 2021-09-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vaccine compositions for hiv prevention and treatment |
| US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2869063B2 (ja) | 1985-04-08 | 1999-03-10 | ジエネテイツク システムズ コ−ポレイシヨン | LAVに対する抗体と免疫的に反応性であるgagによりコードされたペプチドの発現及び使用 |
| US4784941A (en) | 1985-04-08 | 1988-11-15 | Genetic Systems Corporation | Expression and diagnostic use of pENV-3 encoded peptides which are immunologically reactive with antibodies to LAV |
| US4629783A (en) | 1985-04-29 | 1986-12-16 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
| US5175097A (en) | 1985-08-07 | 1992-12-29 | Genetic Systems Corporation | Expression and diagnostic use of GAG-1 encoded peptides which are immunologically reactive with antibodies to HIV |
| US5175098A (en) | 1985-08-07 | 1992-12-29 | Genetic Systems Corporation | Expression and diagnostic use of gag encoded peptides which are immunologically reactive with antibodies to HIV |
| US5134227A (en) | 1986-02-27 | 1992-07-28 | Centocor, Inc. | DNA encoding immunoreactive, chimeric HTLV-III GAG proteins |
| US4808536A (en) | 1986-02-27 | 1989-02-28 | Centocor, Inc. | Immunochemical method for detection of antibody against HTLV-III core protein based upon recombinant HTLV-III gag gene encoded protein |
| US4822606A (en) | 1986-04-07 | 1989-04-18 | Duke University | Immunosuppressive synthetic peptides and analogs thereof based on retroviral envelope sequences |
| US5993819A (en) | 1987-09-08 | 1999-11-30 | Duke University | Synthetic vaccine for protection against human immunodeficiency virus infection |
| GB2220939B (en) | 1988-06-10 | 1992-02-26 | Medical Res Council | Peptide fragments of hiv and their use in vaccines and diagnosis |
| US5817318A (en) | 1989-05-03 | 1998-10-06 | Connaught Laboratories Limited | Synthetic peptides for an HIV-1 vaccine |
| US5210181A (en) | 1989-05-15 | 1993-05-11 | Akzo N.V. | T-lymphotropic retrovirus peptide |
| GB8918200D0 (en) | 1989-08-09 | 1989-09-20 | Medical Res Council | The peptide fragments of hiv |
| CA2025634A1 (en) | 1989-09-19 | 1991-03-20 | Thomas Fuerst | Peptides including ctl epitopes of hiv proteins and use thereof |
| DE3934366A1 (de) | 1989-10-14 | 1991-04-18 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Vakzine zum schutz vor hiv-virusinfektionen, verfahren zu ihrer herstellung und ihre verwendung als diagnostikum und immuntherapeutikum |
| US5480967A (en) | 1990-01-05 | 1996-01-02 | United Biomedical, Inc. | HIV-1 core protein fragments |
| CA2084386C (en) * | 1992-06-04 | 2001-02-20 | Atsushi Saito | Hiv antigen |
| ATE174382T1 (de) | 1992-10-06 | 1998-12-15 | Dade Behring Marburg Gmbh | Retrovirus aus der hiv-gruppe und dessen verwendung |
| BR9406821A (pt) | 1993-06-09 | 1996-03-26 | Connaught Lab | Peptideo sintético composiçao imunogenica kit de diagnostico útil para dectar anticorpos especificos de hiv em amostra de teste kit de diagnostico para detectar antigenos de hiv em amostra de teste codificaçao de molécula de ácido nucléico e anticorpo |
| US6225045B1 (en) | 1996-05-13 | 2001-05-01 | Ribotargets, Ltd. | Assays for screening for inhibitors of HIV |
| US6093400A (en) | 1996-08-09 | 2000-07-25 | Cel Sci Corporation | Modified HGP-30 peptides, conjugates, compositions and methods of use |
| EP0969864A1 (en) * | 1996-08-09 | 2000-01-12 | Viral Technologies, Inc. | Hiv p-17 peptide fragment, compositions containing and methods for producing and using same |
| US6271354B1 (en) | 1997-04-03 | 2001-08-07 | Thomas Jefferson University | Chimeric viral proteins |
| GB9711957D0 (en) | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| WO2000015819A1 (en) * | 1998-09-11 | 2000-03-23 | The Children's Medical Center Corporation | Packaging cell lines for hiv-derived retroviral vector particles |
| AU2150900A (en) * | 1998-11-16 | 2000-06-05 | Board Of Regents, The University Of Texas System | Hiv-specific t-cell induction |
| JP2003523721A (ja) | 1998-12-31 | 2003-08-12 | カイロン コーポレイション | 抗原性hivc型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用 |
| EP1088889A1 (en) * | 1999-10-01 | 2001-04-04 | University Of Cambridge | Recombinant double hybrid filamentous bacteriophage |
-
2000
- 2000-12-22 CA CA2392877A patent/CA2392877C/en not_active Expired - Fee Related
- 2000-12-22 AU AU22089/01A patent/AU784679B2/en not_active Ceased
- 2000-12-22 WO PCT/GB2000/004984 patent/WO2001047955A2/en not_active Ceased
- 2000-12-22 PT PT00985690T patent/PT1240186E/pt unknown
- 2000-12-22 ES ES00985690T patent/ES2341429T3/es not_active Expired - Lifetime
- 2000-12-22 CN CNB008176779A patent/CN1213068C/zh not_active Expired - Fee Related
- 2000-12-22 DK DK00985690.7T patent/DK1240186T3/da active
- 2000-12-22 US US10/168,843 patent/US7993651B2/en not_active Expired - Fee Related
- 2000-12-22 EP EP00985690A patent/EP1240186B1/en not_active Expired - Lifetime
- 2000-12-22 DE DE60043856T patent/DE60043856D1/de not_active Expired - Lifetime
- 2000-12-22 AT AT00985690T patent/ATE457996T1/de active
- 2000-12-22 JP JP2001549425A patent/JP4805511B2/ja not_active Expired - Fee Related
- 2000-12-22 MX MXPA02006379A patent/MXPA02006379A/es active IP Right Grant
- 2000-12-22 BR BR0016510-7A patent/BR0016510A/pt not_active IP Right Cessation
-
2010
- 2010-05-14 CY CY20101100421T patent/CY1110917T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60043856D1 (de) | 2010-04-01 |
| AU2208901A (en) | 2001-07-09 |
| US7993651B2 (en) | 2011-08-09 |
| AU784679B2 (en) | 2006-05-25 |
| JP2003518931A (ja) | 2003-06-17 |
| JP4805511B2 (ja) | 2011-11-02 |
| CA2392877C (en) | 2011-11-15 |
| ES2341429T3 (es) | 2010-06-21 |
| WO2001047955A3 (en) | 2002-05-10 |
| CY1110917T1 (el) | 2015-06-10 |
| MXPA02006379A (es) | 2004-06-21 |
| US20030108562A1 (en) | 2003-06-12 |
| EP1240186B1 (en) | 2010-02-17 |
| EP1240186A2 (en) | 2002-09-18 |
| WO2001047955A2 (en) | 2001-07-05 |
| HK1058048A1 (en) | 2004-04-30 |
| PT1240186E (pt) | 2010-03-25 |
| BR0016510A (pt) | 2002-08-27 |
| ATE457996T1 (de) | 2010-03-15 |
| CN1434831A (zh) | 2003-08-06 |
| CN1213068C (zh) | 2005-08-03 |
| CA2392877A1 (en) | 2001-07-05 |
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