DK1123093T3 - Ubiquinonholdig sammensætning egnet til at fremme øget intramitochondrisk transport af ubiquinoner og fremgangsmåder til at anvende det - Google Patents
Ubiquinonholdig sammensætning egnet til at fremme øget intramitochondrisk transport af ubiquinoner og fremgangsmåder til at anvende detInfo
- Publication number
- DK1123093T3 DK1123093T3 DK99954343T DK99954343T DK1123093T3 DK 1123093 T3 DK1123093 T3 DK 1123093T3 DK 99954343 T DK99954343 T DK 99954343T DK 99954343 T DK99954343 T DK 99954343T DK 1123093 T3 DK1123093 T3 DK 1123093T3
- Authority
- DK
- Denmark
- Prior art keywords
- intramitochondrial
- ubiquinones
- ubiquinone
- transport
- methods
- Prior art date
Links
- 235000017471 coenzyme Q10 Nutrition 0.000 title 2
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title 1
- 230000001737 promoting effect Effects 0.000 title 1
- NPCOQXAVBJJZBQ-UHFFFAOYSA-N reduced coenzyme Q9 Natural products COC1=C(O)C(C)=C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)C(O)=C1OC NPCOQXAVBJJZBQ-UHFFFAOYSA-N 0.000 title 1
- 229940035936 ubiquinone Drugs 0.000 title 1
- 150000003669 ubiquinones Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1998BO000596A IT1304406B1 (it) | 1998-10-21 | 1998-10-21 | Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3. |
| PCT/IT1999/000331 WO2000023069A1 (fr) | 1998-10-21 | 1999-10-19 | Composition renfermant de l'ubiquinone destinee a favoriser le transport intramitochondrial des ubiquinones, et procede d'utilisation de cette composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1123093T3 true DK1123093T3 (da) | 2003-08-11 |
Family
ID=11343466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99954343T DK1123093T3 (da) | 1998-10-21 | 1999-10-19 | Ubiquinonholdig sammensætning egnet til at fremme øget intramitochondrisk transport af ubiquinoner og fremgangsmåder til at anvende det |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6417233B1 (fr) |
| EP (1) | EP1123093B1 (fr) |
| AR (1) | AR023338A1 (fr) |
| AT (1) | ATE237323T1 (fr) |
| AU (1) | AU1074600A (fr) |
| DE (1) | DE69907010T2 (fr) |
| DK (1) | DK1123093T3 (fr) |
| ES (1) | ES2196874T3 (fr) |
| IT (1) | IT1304406B1 (fr) |
| PT (1) | PT1123093E (fr) |
| WO (1) | WO2000023069A1 (fr) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1307281B1 (it) * | 1999-11-25 | 2001-10-30 | Simonelli Giuseppe | Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, |
| JP2004519241A (ja) * | 2001-03-09 | 2004-07-02 | ソシエテ デ プロデユイ ネツスル ソシエテ アノニム | 高齢化に伴う生理的障害を改善し寿命を延ばす組成物 |
| EP1249230B1 (fr) * | 2001-04-12 | 2003-11-05 | Vesifact Ag | Microémulsions et préconcentrés en microémulsion comprenant de la coenzyme Q10 |
| US6582723B2 (en) * | 2001-05-03 | 2003-06-24 | Wayne F. Gorsek | Cancer immune composition for prevention and treatment of individuals |
| JP4603192B2 (ja) * | 2001-05-10 | 2010-12-22 | 株式会社カネカ | 毛髪頭皮用組成物 |
| MXPA03010888A (es) * | 2001-05-30 | 2004-02-27 | Laxdale Ltd | Coenzimas q y acido eicosapentaenoico (epa). |
| US20030229062A1 (en) * | 2001-12-07 | 2003-12-11 | The Regents Of The University Of California | Treatments for age-related macular degeneration (AMD) |
| US7470659B2 (en) * | 2001-12-07 | 2008-12-30 | The Regents Of The University Of California | Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) |
| ITRM20010755A1 (it) * | 2001-12-20 | 2003-06-20 | Simonelli Giuseppe | Uso del chinone q10 per il trattamento delle malattie oculari. |
| TW200302056A (en) * | 2002-01-18 | 2003-08-01 | Kaneka Corp | Method for stabilizing reduced coenzyme Q10 and composition therefor |
| US6974592B2 (en) * | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
| CA2471821C (fr) * | 2002-11-04 | 2006-04-25 | Ocean Nutrition Canada Limited | Microcapsules presentant plusieurs enveloppes et procede de fabrication de celles-ci |
| US20040208939A1 (en) * | 2003-04-18 | 2004-10-21 | Barry Sears | Novel dietary compositions to reduce inflammation |
| US7875291B1 (en) | 2003-09-05 | 2011-01-25 | Glu-Pro, Inc. | Composition for managing diabetes, obesity, and hyperlipidemia and associated methods |
| ITTO20030140U1 (it) * | 2003-09-16 | 2005-03-17 | Interfila Srl | Matita cosmetica |
| TW200524579A (en) * | 2003-11-28 | 2005-08-01 | Kaneka Corp | Composition for protecting liver functions |
| CN1909895A (zh) * | 2004-01-08 | 2007-02-07 | 株式会社钟化 | 抗衰老组合物 |
| ES2631152T3 (es) | 2004-01-22 | 2017-08-28 | University Of Miami | Formulaciones de coenzima Q10 tópicas o intravenosas para su uso en el tratamiento del cáncer |
| US7390507B2 (en) * | 2004-04-13 | 2008-06-24 | Ruwart Mary J | Compositions and methods for the treatment of radiation burns and other traumatic skin conditions |
| DE102004041270A1 (de) * | 2004-08-26 | 2006-03-02 | Merz Pharma Gmbh & Co. Kgaa | Ein Kapillar- Wirksystem enthaltende Zusammensetzungen mit anwendungsbezogener Differenzierbarkeit und deren Verwendung |
| US8034450B2 (en) * | 2005-01-21 | 2011-10-11 | Ocean Nutrition Canada Limited | Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof |
| DE602006011127D1 (de) * | 2005-01-27 | 2010-01-28 | Ocean Nutrition Canada Ltd | Fettsäure-benzenediol-derivate sowie herstellungs- und verwendungsverfahren dafür |
| WO2006109194A2 (fr) * | 2005-01-27 | 2006-10-19 | Ocean Nutrition Canada Ltd. | Composes de chrome et d'acides gras et leurs procedes de fabrication et d'utilisation |
| EP2564843B1 (fr) | 2005-06-01 | 2018-12-26 | Bioelectron Technology Corporation | Produits thérapeutiques actifs en réduction-oxydation destines au traitement de maladies mitochondriales et d'autres états ainsi que la modulation de bio-marqueurs d'énergie |
| US9968120B2 (en) * | 2006-05-17 | 2018-05-15 | Dsm Nutritional Products Ag | Homogenized formulations containing microcapsules and methods of making and using thereof |
| LT1933821T (lt) * | 2005-09-15 | 2020-11-10 | Ptc Therapeutics, Inc. | Šoninės grandinės variantai redoks aktyviųjų terapijos priemonių, skirtų mitochondrinių ligų ir kitokių būklių gydymui ir energijos biologinių žymenų moduliavimui |
| WO2007061752A2 (fr) * | 2005-11-17 | 2007-05-31 | Bioavailability, Inc. | Emulsifiants latents biocompatibles |
| CA2634139C (fr) * | 2005-12-20 | 2015-06-23 | Cenestra, Llc. | Preparations a base d'acide gras omega 3 |
| US20070184041A1 (en) * | 2006-02-09 | 2007-08-09 | Burja Adam M | Methods and compositions related to production of coenzyme q10 |
| EP1986636B1 (fr) | 2006-02-22 | 2013-04-24 | Edison Pharmaceuticals, Inc. | Derives du phenol et de la 1,4-benzoquinone pour leur utilisation dans le traitement des maladies mitochondriales |
| GB0604647D0 (en) | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| CA2643662A1 (fr) * | 2006-04-07 | 2007-10-25 | Ocean Nutrition Canada Ltd. | Emulsions et microcapsules contenant des substances a faible tension interfaciale, leurs procedes de fabrication et d'utilisation |
| US8491888B2 (en) * | 2006-05-05 | 2013-07-23 | Softgel Formulators, Inc. | Highly absorbable coenzyme Q10 composition and method of producing same |
| PL2040682T3 (pl) * | 2006-06-05 | 2018-01-31 | Dsm Nutritional Products Ag | Mikrokapsułki o ulepszonych otoczkach |
| KR100801057B1 (ko) * | 2006-07-18 | 2008-02-04 | 삼성전자주식회사 | 컬러 보정 블럭을 구비하는 cmos 이미지 센서 및 그이미지 센싱 방법 |
| US8894993B2 (en) * | 2006-08-04 | 2014-11-25 | Natreon Inc. | Mitochondria-targeted antioxidants |
| KR101430214B1 (ko) * | 2006-12-28 | 2014-08-18 | 산토리 홀딩스 가부시키가이샤 | 신경 재생제 |
| AU2008205325B2 (en) | 2007-01-10 | 2013-09-12 | Dsm Nutritional Products Ag | Vegetarian microcapsules |
| HUP0700552A2 (en) | 2007-08-27 | 2009-03-30 | Janos Dr Feher | Method and composition inhibiting inflammation |
| US8343753B2 (en) * | 2007-11-01 | 2013-01-01 | Wake Forest University School Of Medicine | Compositions, methods, and kits for polyunsaturated fatty acids from microalgae |
| KR100943652B1 (ko) * | 2007-12-28 | 2010-02-25 | (주)미토콘 | 생체이용율이 향상된 코엔자임큐10 함유 조성물 |
| EP2271325A4 (fr) | 2008-04-11 | 2011-11-09 | Cytotech Labs Llc | Procédés et utilisation d'induction de l'apoptose dans des cellules cancéreuses |
| US8535660B1 (en) | 2008-05-27 | 2013-09-17 | Argent Development Group, Llc | Nutritional supplements for pregnant women |
| US8535659B1 (en) | 2008-05-27 | 2013-09-17 | Argent Development Group, Llc | Nutritional supplements for pregnant women |
| MX363223B (es) | 2008-09-10 | 2019-03-15 | Bioelectron Tech Corp | Tratamiento de trastornos generalizados del desarrollo con terapeuticos con actividad redox. |
| US20110071090A1 (en) * | 2009-03-11 | 2011-03-24 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle |
| US8993625B2 (en) | 2009-03-11 | 2015-03-31 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle |
| US9034389B2 (en) | 2009-03-11 | 2015-05-19 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| IT1393419B1 (it) * | 2009-03-19 | 2012-04-20 | Medivis S R L | Composizioni oftalmiche a base di acidi grassi polinsaturi omega-3 e omega-6. |
| WO2010111397A1 (fr) * | 2009-03-24 | 2010-09-30 | Adds Pharmaceuticals Llc | Formulations stabilisées à solubilité accrue pour administration par voie orale |
| US10519504B2 (en) * | 2009-05-11 | 2019-12-31 | Berg Llc | Methods for treatment of oncological disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers |
| AU2010313249B2 (en) * | 2009-10-30 | 2016-05-19 | Biojiva Llc | Alleviating oxidative stress disorders with PUFA derivatives |
| US11400058B2 (en) * | 2010-03-12 | 2022-08-02 | Berg Llc | Intravenous formulations of coenzyme Q10 (CoQ10) and methods of use thereof |
| EP2694463B8 (fr) | 2011-04-04 | 2019-10-09 | Berg LLC | Traitement de tumeurs du système nerveux central avec coenzyme q10 |
| CA2834342C (fr) | 2011-04-26 | 2021-08-31 | Retrotope, Inc. | Troubles de traitement compromis de l'energie et deficiences mitochondriales |
| US10154983B2 (en) | 2011-04-26 | 2018-12-18 | Retrotope, Inc. | Neurodegenerative disorders and muscle diseases implicating PUFAs |
| DK2701697T3 (da) | 2011-04-26 | 2020-06-29 | Retrotope Inc | Oxidative nethindesygdomme |
| KR102110175B1 (ko) | 2011-04-26 | 2020-05-13 | 레트로토프 인코포레이티드 | Pufa 산화와 관련된 장애 |
| US9464016B2 (en) | 2011-06-14 | 2016-10-11 | Edison Pharmaceuticals, Inc. | Catechol derivatives for treatment of oxidative stress diseases |
| EA201490047A1 (ru) | 2011-06-17 | 2014-08-29 | Берг Ллк | Ингаляционные фармацевтические композиции |
| US20140274966A1 (en) * | 2013-03-14 | 2014-09-18 | Hygia Pharmaceuticals, Llc | Drink Product Containing Genistein and Use Thereof |
| EA032775B1 (ru) | 2013-04-08 | 2019-07-31 | Берг Ллк | Способы лечения злокачественной опухоли с использованием комбинированной терапии с коферментом q10 |
| AU2014285095A1 (en) * | 2013-07-03 | 2016-02-25 | Barrie Tan | CoQ10 (ubiquinone, ubiquinol), vitamin A (retinoic acid, retinol), vitamin E (tocotrienol, tocopherol) and methods of use |
| WO2015035094A1 (fr) | 2013-09-04 | 2015-03-12 | Berg Llc | Procédés de traitement du cancer par perfusion continue de coenzyme q10 |
| US9138453B2 (en) | 2013-10-14 | 2015-09-22 | Biomarker Pharmaceuticals, Inc. | Nutrient combinations for affecting an aging process |
| WO2017087576A1 (fr) | 2015-11-16 | 2017-05-26 | Berg Llc | Procédés de traitement de gliome résistant au témozolomide utilisant la coenzyme q10 |
| EP3950649A1 (fr) | 2015-11-23 | 2022-02-09 | Retrotope, Inc. | Marquage isotopique spécifique de site de systèmes 1,4-diènes |
| DE202015106479U1 (de) | 2015-11-29 | 2016-03-09 | Cathleen Straßburger | Stapelhilfe und Abdeckhaube für den Transport von Cateringmaterial zum Kunden |
| WO2017106803A1 (fr) | 2015-12-17 | 2017-06-22 | Bioelectron Technology Corporation | Dérivés fluoroalkyle, fluoroalcoxy, phénoxy, hétéroaryloxy, alcoxy, et amine 1,4-benzoquinone pour le traitement de troubles du stress oxydatif |
| KR20220143931A (ko) | 2020-02-21 | 2022-10-25 | 레트로토프 인코포레이티드 | 고도불포화 지방산 및 이의 유도체의 동위원소 변형을 위한 공정 |
| US12109194B2 (en) | 2021-02-05 | 2024-10-08 | Biojiva Llc | Synergistic combination therapy for treating ALS |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5618914A (en) | 1979-07-25 | 1981-02-23 | Eisai Co Ltd | Ubidecarenone composition having good absorbability |
| DE3224619A1 (de) | 1981-07-14 | 1983-05-19 | Freund Industrial Co., Ltd., Tokyo | Orale pharmazeutische zusammensetzung |
| JP2643217B2 (ja) | 1988-01-22 | 1997-08-20 | エーザイ株式会社 | 脂溶性物質水性液 |
| US5895652A (en) * | 1996-07-29 | 1999-04-20 | Longevity Institute International | Method of metabolic adjuvanation and cellular repair |
| NO304009B1 (no) | 1997-02-04 | 1998-10-12 | Gunnar Volden | Hudpreparat |
| CA2260397A1 (fr) * | 1999-01-29 | 2000-07-29 | Atlantis Marine Inc. | Methode pour convertir l'huile fondue de triglyceride provenant de sources marines en huile alimentaire douce et stable |
-
1998
- 1998-10-21 IT IT1998BO000596A patent/IT1304406B1/it active
-
1999
- 1999-10-19 WO PCT/IT1999/000331 patent/WO2000023069A1/fr not_active Ceased
- 1999-10-19 DK DK99954343T patent/DK1123093T3/da active
- 1999-10-19 PT PT99954343T patent/PT1123093E/pt unknown
- 1999-10-19 ES ES99954343T patent/ES2196874T3/es not_active Expired - Lifetime
- 1999-10-19 AU AU10746/00A patent/AU1074600A/en not_active Abandoned
- 1999-10-19 EP EP99954343A patent/EP1123093B1/fr not_active Revoked
- 1999-10-19 US US09/807,918 patent/US6417233B1/en not_active Expired - Fee Related
- 1999-10-19 AT AT99954343T patent/ATE237323T1/de active
- 1999-10-19 DE DE69907010T patent/DE69907010T2/de not_active Revoked
- 1999-10-21 AR ARP990105327A patent/AR023338A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ITBO980596A0 (it) | 1998-10-21 |
| ITBO980596A1 (it) | 2000-04-21 |
| US6417233B1 (en) | 2002-07-09 |
| WO2000023069A1 (fr) | 2000-04-27 |
| AR023338A1 (es) | 2002-09-04 |
| PT1123093E (pt) | 2003-09-30 |
| EP1123093B1 (fr) | 2003-04-16 |
| DE69907010T2 (de) | 2004-02-19 |
| DE69907010D1 (de) | 2003-05-22 |
| IT1304406B1 (it) | 2001-03-19 |
| ES2196874T3 (es) | 2003-12-16 |
| AU1074600A (en) | 2000-05-08 |
| EP1123093A1 (fr) | 2001-08-16 |
| ATE237323T1 (de) | 2003-05-15 |
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