DK1115380T4 - Mikroniserede farmaceutiske præparater - Google Patents

Mikroniserede farmaceutiske præparater

Info

Publication number: DK1115380T4
Authority: DK; Denmark
Prior art keywords: pharmaceutical preparations; micronized pharmaceutical; micronised; pharmaceutical compositions; micronized
Prior art date: 1998-09-23

Application number

DK99949133T

Other languages

Danish (da)

English (en)

Other versions

DK1115380T3 (da

Inventor

Richard Anthony Flynn

Martin Harris Goldman

James Richard Lovely

Original Assignee

Forest Lab Uk Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-23

Filing date

1999-09-22

Publication date

2008-06-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10839350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1115380(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-09-22 Application filed by Forest Lab Uk Ltd filed Critical Forest Lab Uk Ltd

2004-10-04 Application granted granted Critical

2004-10-04 Publication of DK1115380T3 publication Critical patent/DK1115380T3/da

2008-06-16 Publication of DK1115380T4 publication Critical patent/DK1115380T4/da

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 abstract 2
108010078777 Colistin Proteins 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
229960003346 colistin Drugs 0.000 abstract 1
239000007903 gelatin capsule Substances 0.000 abstract 1
239000008101 lactose Substances 0.000 abstract 1
JORAUNFTUVJTNG-BSTBCYLQSA-N n-[(2s)-4-amino-1-[[(2s,3r)-1-[[(2s)-4-amino-1-oxo-1-[[(3s,6s,9s,12s,15r,18s,21s)-6,9,18-tris(2-aminoethyl)-3-[(1r)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-h Chemical compound CC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O.CCC(C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@H]([C@@H](C)O)CN[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O JORAUNFTUVJTNG-BSTBCYLQSA-N 0.000 abstract 1
XDJYMJULXQKGMM-UHFFFAOYSA-N polymyxin E1 Natural products CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O XDJYMJULXQKGMM-UHFFFAOYSA-N 0.000 abstract 1
KNIWPHSUTGNZST-UHFFFAOYSA-N polymyxin E2 Natural products CC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1=O KNIWPHSUTGNZST-UHFFFAOYSA-N 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Gastroenterology & Hepatology (AREA)
Otolaryngology (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK99949133T 1998-09-23 1999-09-22 Mikroniserede farmaceutiske præparater DK1115380T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9820746.7A GB9820746D0 (en)	1998-09-23	1998-09-23	Micronised pharmaceutical compositions
PCT/GB1999/003172 WO2000016745A2 (fr)	1998-09-23	1999-09-22	Compositions pharmaceutiques microfines

Publications (2)

Publication Number	Publication Date
DK1115380T3 DK1115380T3 (da)	2004-10-04
DK1115380T4 true DK1115380T4 (da)	2008-06-16

Family

ID=10839350

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99949133T DK1115380T4 (da)	1998-09-23	1999-09-22	Mikroniserede farmaceutiske præparater

Country Status (20)

Country	Link
EP (1)	EP1115380B2 (fr)
JP (1)	JP5165168B2 (fr)
CN (1)	CN1148168C (fr)
AT (1)	ATE267585T1 (fr)
AU (1)	AU752266B2 (fr)
BR (2)	BRPI9914031B8 (fr)
CA (1)	CA2341366C (fr)
CZ (1)	CZ298603B6 (fr)
DE (1)	DE69917658T3 (fr)
DK (1)	DK1115380T4 (fr)
EA (1)	EA003193B1 (fr)
ES (1)	ES2222733T5 (fr)
GB (1)	GB9820746D0 (fr)
HU (1)	HU228888B1 (fr)
IL (1)	IL141913A0 (fr)
MX (1)	MXPA01003103A (fr)
NZ (1)	NZ509881A (fr)
PL (1)	PL197871B1 (fr)
PT (1)	PT1115380E (fr)
WO (1)	WO2000016745A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1129705A1 (fr) *	2000-02-17	2001-09-05	Rijksuniversiteit te Groningen	Formulation en poudre pour inhalation
WO2005053647A1 (fr) *	2003-12-03	2005-06-16	Microdrug Ag	Produit medical contenant du tiotropium
SE0303570L (sv) *	2003-12-03	2005-06-04	Microdrug Ag	Fukt-känslig medicinsk produkt
WO2012061902A1 (fr) *	2010-11-12	2012-05-18	Monash University	Particules micronisées séchées par atomisation comprenant de la polymyxine
MX2015012931A (es) *	2013-03-13	2016-07-20	Forest Lab Holdings Ltd	Composiciones farmaceuticas micronizadas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4564614A (en) *	1984-10-11	1986-01-14	Pfizer Inc.	Antiinflammatory methods
IT1228459B (it) †	1989-02-23	1991-06-19	Phidea S R L	Inalatore con svuotamento regolare e completo della capsula.
GB8911259D0 (en) †	1989-05-17	1989-07-05	Fisons Plc	Inhalation medicament
US5916596A (en) †	1993-02-22	1999-06-29	Vivorx Pharmaceuticals, Inc.	Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
IS1796B (is) *	1993-06-24	2001-12-31	Ab Astra	Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US5875776A (en) †	1996-04-09	1999-03-02	Vivorx Pharmaceuticals, Inc.	Dry powder inhaler
JP2001505557A (ja) *	1996-11-15	2001-04-24	パソジェネシスコーポレイション	肺感染を処置するための、純粋な生物学的活性コリスチン、その成分、およびコリスチン処方物

1998
- 1998-09-23 GB GBGB9820746.7A patent/GB9820746D0/en not_active Ceased
1999
- 1999-09-22 CA CA002341366A patent/CA2341366C/fr not_active Expired - Lifetime
- 1999-09-22 MX MXPA01003103A patent/MXPA01003103A/es active IP Right Grant
- 1999-09-22 EA EA200100253A patent/EA003193B1/ru not_active IP Right Cessation
- 1999-09-22 AU AU62122/99A patent/AU752266B2/en not_active Expired
- 1999-09-22 DE DE69917658T patent/DE69917658T3/de not_active Expired - Lifetime
- 1999-09-22 PT PT99949133T patent/PT1115380E/pt unknown
- 1999-09-22 HU HU0104928A patent/HU228888B1/hu active Protection Beyond IP Right Term
- 1999-09-22 ES ES99949133T patent/ES2222733T5/es not_active Expired - Lifetime
- 1999-09-22 IL IL14191399A patent/IL141913A0/xx not_active IP Right Cessation
- 1999-09-22 EP EP99949133A patent/EP1115380B2/fr not_active Expired - Lifetime
- 1999-09-22 BR BRPI9914031A patent/BRPI9914031B8/pt unknown
- 1999-09-22 CZ CZ20011050A patent/CZ298603B6/cs not_active IP Right Cessation
- 1999-09-22 PL PL346774A patent/PL197871B1/pl unknown
- 1999-09-22 BR BRPI9914031-4A patent/BR9914031B1/pt not_active IP Right Cessation
- 1999-09-22 JP JP2000573706A patent/JP5165168B2/ja not_active Expired - Lifetime
- 1999-09-22 AT AT99949133T patent/ATE267585T1/de not_active IP Right Cessation
- 1999-09-22 WO PCT/GB1999/003172 patent/WO2000016745A2/fr not_active Ceased
- 1999-09-22 NZ NZ509881A patent/NZ509881A/xx not_active IP Right Cessation
- 1999-09-22 CN CNB998113360A patent/CN1148168C/zh not_active Expired - Lifetime
- 1999-09-22 DK DK99949133T patent/DK1115380T4/da active

Also Published As

Publication number	Publication date
BRPI9914031B8 (pt)	2019-02-26
IL141913A0 (en)	2002-03-10
BR9914031A (pt)	2001-06-19
CA2341366A1 (fr)	2000-03-30
WO2000016745A2 (fr)	2000-03-30
EA200100253A1 (ru)	2001-08-27
CZ298603B6 (cs)	2007-11-21
EP1115380A2 (fr)	2001-07-18
CN1148168C (zh)	2004-05-05
HU228888B1 (en)	2013-06-28
ATE267585T1 (de)	2004-06-15
JP2002526435A (ja)	2002-08-20
EA003193B1 (ru)	2003-02-27
AU752266B2 (en)	2002-09-12
MXPA01003103A (es)	2005-02-17
HUP0104928A3 (en)	2002-08-28
BR9914031B1 (pt)	2011-02-08
DE69917658D1 (de)	2004-07-01
CA2341366C (fr)	2008-11-18
AU6212299A (en)	2000-04-10
HUP0104928A2 (hu)	2002-04-29
EP1115380B1 (fr)	2004-05-26
DK1115380T3 (da)	2004-10-04
ES2222733T3 (es)	2005-02-01
PT1115380E (pt)	2004-10-29
EP1115380B2 (fr)	2008-03-12
DE69917658T2 (de)	2005-06-09
JP5165168B2 (ja)	2013-03-21
DE69917658T3 (de)	2009-04-02
NZ509881A (en)	2003-01-31
CZ20011050A3 (cs)	2001-09-12
ES2222733T5 (es)	2008-06-16
PL346774A1 (en)	2002-02-25
GB9820746D0 (en)	1998-11-18
CN1321082A (zh)	2001-11-07
WO2000016745A3 (fr)	2001-05-10
PL197871B1 (pl)	2008-05-30

Publication	Publication Date	Title
MY126253A (en)	2006-09-29	Capsules for inhalation
IL133397A (en)	2005-07-25	Pharmaceutical compositions for oral administration comprising an active substance and a cyclodextrin
GR3004448T3 (fr)	1993-03-31
IL90435A (en)	1993-02-21	4-(quinoline-2-yl-methoxy) phenylacetic acid derivatives, their preparation and pharmaceutical compositions containing them
NO20100302L (no)	2000-10-04	Sammensetninger som inneholder organiske forbindelser
MY101847A (en)	1992-01-31	Composition for solid pharmaceutical preparations of active vitamins d 3 and process for preparation thereof.
YU57600A (sh)	2003-10-31	Derivarti biciklične hidroksaminske kiseline
BR0003158A (pt)	2001-12-18	Formulação de dosagem oral de derretimentoinstantâneo
NO970068D0 (no)	1997-01-08	Inhaleringssammensetning
YU38802A (sh)	2005-03-15	Nova kompozicija i njena upotreba
AU1811688A (en)	1988-12-22	Solid drug preparations containing micronized crystals of ebselen
TNSN05046A1 (en)	2007-05-14	Method of preparing dry powder inhalation compositions
NZ336592A (en)	2001-01-26	Formulation for inhalation having a poured bulk density of from 0.28 to 0.38 g/ml comprising finely divided budesonide and a carrier
GEP20043383B (en)	2004-07-12	Cell Adhesion-Inhibiting Antiinflammatory and Immune-Suppressive Compounds
DK1115380T4 (da)	2008-06-16	Mikroniserede farmaceutiske præparater
GEP20043377B (en)	2004-04-13	Pharmaceutical Complex
PT1001942E (pt)	2003-11-28	Poli-hidroxibutilpirazinas sua preparacao e medicamentos que as contem
PT989994E (pt)	2005-08-31	Derivados de estreptograminas, a sua preparacao e as composicoes que os contem
BG104452A (en)	2000-12-29	New derivatives of the methylenebisphosphonic acid
IL97509A0 (en)	1992-06-21	Lipid lowering compositions comprising bambuterol
AU2001287489A1 (en)	2002-02-18	New agarofuran derivatives, their preparations, pharmaceutical compositions containing them and their uses as medicaments
GB1446237A (en)	1976-08-18	Pharmaceutical preparations containing pyrazolones