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DK1189971T3 - Funktionelle poly-alpha-aminosyrederivater der er egnede til modificering af biologisk aktive materialer, samt anvendelse deraf - Google Patents

Funktionelle poly-alpha-aminosyrederivater der er egnede til modificering af biologisk aktive materialer, samt anvendelse deraf

Info

Publication number
DK1189971T3
DK1189971T3 DK00938349T DK00938349T DK1189971T3 DK 1189971 T3 DK1189971 T3 DK 1189971T3 DK 00938349 T DK00938349 T DK 00938349T DK 00938349 T DK00938349 T DK 00938349T DK 1189971 T3 DK1189971 T3 DK 1189971T3
Authority
DK
Denmark
Prior art keywords
alpha
biologically active
active materials
amino acid
acid derivatives
Prior art date
Application number
DK00938349T
Other languages
English (en)
Inventor
Etienne Honore Schacht
Veska Toncheva
Original Assignee
Univ Gent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Gent filed Critical Univ Gent
Application granted granted Critical
Publication of DK1189971T3 publication Critical patent/DK1189971T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C08G73/1092—Polysuccinimides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyamides (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK00938349T 1999-06-17 2000-06-19 Funktionelle poly-alpha-aminosyrederivater der er egnede til modificering af biologisk aktive materialer, samt anvendelse deraf DK1189971T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99870125 1999-06-17
PCT/BE2000/000066 WO2000078791A2 (en) 1999-06-17 2000-06-19 FUNCTIONAL POLY-α-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION
EP00938349A EP1189971B1 (en) 1999-06-17 2000-06-19 Functional poly-alpha-aminoacid derivatives useful for the modification of biologically active materials and their application

Publications (1)

Publication Number Publication Date
DK1189971T3 true DK1189971T3 (da) 2005-07-11

Family

ID=8243853

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00938349T DK1189971T3 (da) 1999-06-17 2000-06-19 Funktionelle poly-alpha-aminosyrederivater der er egnede til modificering af biologisk aktive materialer, samt anvendelse deraf

Country Status (9)

Country Link
US (1) US7005123B1 (da)
EP (1) EP1189971B1 (da)
AT (1) ATE290564T1 (da)
AU (1) AU5376500A (da)
CA (1) CA2377267A1 (da)
DE (1) DE60018564T2 (da)
DK (1) DK1189971T3 (da)
ES (1) ES2239602T3 (da)
WO (1) WO2000078791A2 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935302A1 (de) 1999-07-28 2001-02-08 Aventis Pharma Gmbh Konjugate und Verfahren zu deren Herstellung sowie deren Verwendung zum Transport von Molekülen über biologische Membranen
CA2401327C (en) 2000-03-03 2014-05-06 Valentis, Inc. Nucleic acid formulations comprising poly-amino acids for gene delivery and methods of use
DE10154924A1 (de) * 2001-11-08 2003-05-28 Medinnova Ges Med Innovationen Bioabbaubare Kopolymere
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
ATE485331T1 (de) 2003-01-06 2010-11-15 Nektar Therapeutics Thiolselektive wasserlösliche polymerderivate
US7833714B1 (en) 2003-04-11 2010-11-16 Affymetrix, Inc. Combinatorial affinity selection
FR2855521B1 (fr) * 2003-05-28 2005-08-05 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.
FR2858976B1 (fr) * 2003-08-22 2006-02-10 Isochem Sa Procede d'obtention de n-carboxyanhydrides d'alpha-aminoacides a protection urethane
FR2860516B1 (fr) * 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
EP1923075B1 (en) * 2004-08-13 2015-11-11 Rutgers, The State University Radiopaque polymeric stents
US20060147940A1 (en) * 2004-12-30 2006-07-06 Affymetrix, Inc. Combinatorial affinity selection
EP2206736B1 (en) 2005-12-05 2012-02-08 Nitto Denko Corporation Polyglutamate-amino acid conjugates and methods
WO2009058291A2 (en) * 2007-10-31 2009-05-07 University Of Alabama In Huntsville Controlled molecular weight amino acid polymers having functionalizable backbones and end groups and processes for preparing the same
WO2009153209A1 (en) * 2008-06-19 2009-12-23 Henkel Ag & Co. Kgaa Modified polymeric pro-fragrance
WO2012027204A1 (en) * 2010-08-26 2012-03-01 Nitto Denko Corporation End-capped polymers
CN102250353B (zh) * 2011-05-23 2012-10-10 黑龙江大学 多组分蒸发结晶共聚改性合成聚天冬氨酸衍生物的方法
CN106478873B (zh) * 2015-08-31 2018-07-20 中国石油化工股份有限公司 一种共聚物及其制备方法与应用
CN106478874B (zh) * 2015-08-31 2018-07-20 中国石油化工股份有限公司 一种共聚物及其制备方法与应用
CN109593195B (zh) * 2018-12-04 2021-04-30 陕西科技大学 一锅法制备功能化多肽的方法
CN119390963B (zh) * 2024-12-30 2025-04-29 浙江大学 一种聚肽酯醚胺无规聚合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1049576B (de) * 1955-02-22 1959-01-29 Courtaulds Limited, London Verfahren zur Herstellung von Polyamiden
GB9606975D0 (en) * 1996-04-02 1996-06-05 Univ Birmingham Anti-tumor agent
GB9623051D0 (en) * 1996-11-06 1997-01-08 Schacht Etienne H Delivery of DNA to target cells in biological systems

Also Published As

Publication number Publication date
AU5376500A (en) 2001-01-09
ATE290564T1 (de) 2005-03-15
CA2377267A1 (en) 2000-12-28
ES2239602T3 (es) 2005-10-01
EP1189971A2 (en) 2002-03-27
US7005123B1 (en) 2006-02-28
EP1189971B1 (en) 2005-03-09
DE60018564T2 (de) 2006-05-24
WO2000078791A2 (en) 2000-12-28
WO2000078791A3 (en) 2001-12-13
DE60018564D1 (de) 2005-04-14

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