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DK1189627T3 - Compositions containing soluble forms of HLA-G for the treatment of inflammatory pathological conditions in the skin - Google Patents

Compositions containing soluble forms of HLA-G for the treatment of inflammatory pathological conditions in the skin

Info

Publication number
DK1189627T3
DK1189627T3 DK00951595T DK00951595T DK1189627T3 DK 1189627 T3 DK1189627 T3 DK 1189627T3 DK 00951595 T DK00951595 T DK 00951595T DK 00951595 T DK00951595 T DK 00951595T DK 1189627 T3 DK1189627 T3 DK 1189627T3
Authority
DK
Denmark
Prior art keywords
hla
skin
soluble forms
pathological conditions
treatment
Prior art date
Application number
DK00951595T
Other languages
Danish (da)
Inventor
Selim Aractingi
Edgardo Delfino Carosella
Jean Dausset
Daher Iman Khalil
Philippe Moreau
Pascale Paul
Nathalie Rouas-Freiss
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of DK1189627T3 publication Critical patent/DK1189627T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention concerns a composition consisting essentially of at least a soluble form of HLA-G and at least an acceptable pharmaceutical carrier for preparing a medicine for treating inflammatory pathological conditions of the skin. The invention also concerns a method for obtaining soluble forms of HLA-G and antibodies directed against said soluble forms.
DK00951595T 1999-06-18 2000-06-16 Compositions containing soluble forms of HLA-G for the treatment of inflammatory pathological conditions in the skin DK1189627T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9907736A FR2794977B1 (en) 1999-06-18 1999-06-18 USE OF COMPOSITIONS CONTAINING SOLUBLE FORMS OF HLA-G IN THE TREATMENT OF INFLAMMATORY SKIN CONDITIONS AND THEIR METHOD OF OBTAINING
PCT/FR2000/001670 WO2000078337A1 (en) 1999-06-18 2000-06-16 Compositions containing soluble forms of hla-g for treating inflammatory skin pathologies

Publications (1)

Publication Number Publication Date
DK1189627T3 true DK1189627T3 (en) 2004-02-16

Family

ID=9546968

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00951595T DK1189627T3 (en) 1999-06-18 2000-06-16 Compositions containing soluble forms of HLA-G for the treatment of inflammatory pathological conditions in the skin

Country Status (10)

Country Link
EP (1) EP1189627B1 (en)
JP (1) JP2003508351A (en)
AT (1) ATE251911T1 (en)
CA (1) CA2377519C (en)
DE (1) DE60005952T8 (en)
DK (1) DK1189627T3 (en)
ES (1) ES2206286T3 (en)
FR (1) FR2794977B1 (en)
IL (2) IL147123A0 (en)
WO (1) WO2000078337A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2810047B1 (en) * 2000-06-13 2004-04-02 Commissariat Energie Atomique NEW ISOFORM OF HLA-G AND ITS APPLICATIONS
WO2007011044A1 (en) * 2005-07-15 2007-01-25 Kyushu University, National University Corporation Pharmaceutical composition comprising disulfide-linked hla-g dimer and process for production of disulfide-linked hla-g dimer
WO2008058913A1 (en) 2006-11-15 2008-05-22 Basf Se Process for producing flexible polyurethane foams
EP2184297A1 (en) * 2008-11-07 2010-05-12 Hla-G Technologies HLA-G polypeptides and pharmaceutical uses thereof
EP2184070A1 (en) 2008-11-07 2010-05-12 Hla-G Technologies HLA-G proteins and pharmaceutical uses thereof
EP2264067A1 (en) 2009-06-18 2010-12-22 Hla-G Technologies HLA-G alpha 1 multimers and pharmaceutical uses thereof
US20120178703A1 (en) 2009-06-25 2012-07-12 Commisariat A L'energie Atomique Et Aux Energies Alternatives Multimeric polypeptides of hla-g including at least two alpha3 domains and pharmaceutical uses thereof
CN102892432A (en) * 2010-05-28 2013-01-23 国家医疗保健研究所 Anti-CD160 specific antibodies for the treatment of neovascularization-based ocular diseases
CN119185534A (en) 2017-05-23 2024-12-27 尤利乌斯·马克西米利安维尔茨堡大学 Combination of MHC class Ib molecules and peptides for targeted therapeutic immunomodulation
AU2020307667A1 (en) 2019-06-27 2022-01-20 Crispr Therapeutics Ag Use of chimeric antigen receptor T cells and NK cell inhibitors for treating cancer
CN114341172A (en) * 2019-07-05 2022-04-12 英特莱克森有限责任公司 HLA-H in medicine and diagnostics
EP4171585A1 (en) 2020-06-26 2023-05-03 CRISPR Therapeutics AG Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717498B1 (en) * 1994-03-18 1996-05-03 Commissariat Energie Atomique Transcripts of the HLA-G class I MHC gene and their applications.
EP0819171A1 (en) * 1995-04-07 1998-01-21 The Regents Of The University Of California Antibodies for the detection of hla-g
CA2221687A1 (en) * 1997-02-05 1998-08-05 Smithkline Beecham Corporation Tumor necrosis related receptor, tr5
FR2760023B1 (en) * 1997-02-21 2004-05-07 Commissariat Energie Atomique EUKARYOTIC CELLS EXPRESSING AT THEIR SURFACE AT LEAST ONE ISOFORM OF HLA-G AND THEIR APPLICATIONS

Also Published As

Publication number Publication date
ES2206286T3 (en) 2004-05-16
JP2003508351A (en) 2003-03-04
DE60005952T2 (en) 2004-07-29
CA2377519A1 (en) 2000-12-28
FR2794977B1 (en) 2003-10-31
FR2794977A1 (en) 2000-12-22
DE60005952D1 (en) 2003-11-20
CA2377519C (en) 2011-09-27
DE60005952T8 (en) 2004-11-04
EP1189627B1 (en) 2003-10-15
IL147123A (en) 2010-06-30
EP1189627A1 (en) 2002-03-27
WO2000078337A1 (en) 2000-12-28
IL147123A0 (en) 2002-08-14
ATE251911T1 (en) 2003-11-15

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