DK1187617T3 - Fremgangsmåde til at vælge koncentrationen af et amfipatisk antihistaminlægemiddel ved at bestemme lægemidlets overfladeaktivitetsmåltal - Google Patents
Fremgangsmåde til at vælge koncentrationen af et amfipatisk antihistaminlægemiddel ved at bestemme lægemidlets overfladeaktivitetsmåltalInfo
- Publication number
- DK1187617T3 DK1187617T3 DK00917998T DK00917998T DK1187617T3 DK 1187617 T3 DK1187617 T3 DK 1187617T3 DK 00917998 T DK00917998 T DK 00917998T DK 00917998 T DK00917998 T DK 00917998T DK 1187617 T3 DK1187617 T3 DK 1187617T3
- Authority
- DK
- Denmark
- Prior art keywords
- drug
- surface activity
- amphipathic
- selecting
- concentration
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 229940124623 antihistamine drug Drugs 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 239000000043 antiallergic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13994599P | 1999-06-18 | 1999-06-18 | |
| US15817799P | 1999-10-07 | 1999-10-07 | |
| PCT/US2000/006890 WO2000078396A2 (en) | 1999-06-18 | 2000-03-16 | Topical ophthalmic mast cell stabilizers for treating allergic eye diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1187617T3 true DK1187617T3 (da) | 2004-04-13 |
Family
ID=26837695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00917998T DK1187617T3 (da) | 1999-06-18 | 2000-03-16 | Fremgangsmåde til at vælge koncentrationen af et amfipatisk antihistaminlægemiddel ved at bestemme lægemidlets overfladeaktivitetsmåltal |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6420399B1 (da) |
| EP (1) | EP1187617B1 (da) |
| JP (1) | JP4851035B2 (da) |
| AT (1) | ATE260660T1 (da) |
| AU (1) | AU770975B2 (da) |
| CA (1) | CA2374002A1 (da) |
| DE (1) | DE60008730T2 (da) |
| DK (1) | DK1187617T3 (da) |
| ES (1) | ES2213001T3 (da) |
| PT (1) | PT1187617E (da) |
| WO (1) | WO2000078396A2 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2316394B1 (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery |
| RU2247966C1 (ru) * | 2003-12-04 | 2005-03-10 | Тюменский государственный университет | Способ измерения концентрации поверхностно-активного вещества |
| US7276050B2 (en) * | 2004-03-02 | 2007-10-02 | Alan Franklin | Trans-scleral drug delivery method and apparatus |
| US20050239745A1 (en) * | 2004-03-03 | 2005-10-27 | Ophthalmic Research Associates, Inc. | Novel topical ophthalmic formulations |
| JP5315051B2 (ja) * | 2005-07-08 | 2013-10-16 | 千寿製薬株式会社 | オロパタジンを含む眼科用経皮吸収型製剤 |
| US8399006B2 (en) | 2009-01-29 | 2013-03-19 | Forsight Vision4, Inc. | Posterior segment drug delivery |
| US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
| ES2894940T3 (es) | 2010-08-05 | 2022-02-16 | Forsight Vision4 Inc | Aparato para tratar un ojo |
| PL2600930T3 (pl) | 2010-08-05 | 2021-09-06 | Forsight Vision4, Inc. | Urządzenie wstrzykujące do dostarczania leku |
| EP2600876B1 (en) | 2010-08-05 | 2015-04-29 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
| CA2818612C (en) | 2010-11-19 | 2020-12-29 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
| TWI544922B (zh) | 2011-05-19 | 2016-08-11 | 愛爾康研究有限公司 | 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物 |
| EP2726016B1 (en) | 2011-06-28 | 2023-07-19 | ForSight Vision4, Inc. | An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye |
| EP2739252A4 (en) | 2011-08-05 | 2015-08-12 | Forsight Vision4 Inc | SMALL MOLECULE ADMINISTRATION USING AN IMPLANTABLE THERAPEUTIC DEVICE |
| SI2755600T1 (sl) | 2011-09-16 | 2021-08-31 | Forsight Vision4, Inc. | Naprava za izmenjavo tekočine |
| WO2013116061A1 (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
| US9968603B2 (en) | 2013-03-14 | 2018-05-15 | Forsight Vision4, Inc. | Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant |
| CN105246438B (zh) | 2013-03-28 | 2018-01-26 | 弗赛特影像4股份有限公司 | 用于输送治疗物质的眼科植入物 |
| CA2955186C (en) | 2014-07-15 | 2023-08-29 | Forsight Vision4, Inc. | Ocular implant delivery device and method |
| JP2017524034A (ja) | 2014-08-08 | 2017-08-24 | フォーサイト・ビジョン フォー・インコーポレーテッドＦｏｒｓｉｇｈｔ Ｖｉｓｉｏｎ４， Ｉｎｃ． | 受容体型チロシンキナーゼ阻害剤の安定で可溶な製剤およびその調製の方法 |
| WO2016077371A1 (en) | 2014-11-10 | 2016-05-19 | Forsight Vision4, Inc. | Expandable drug delivery devices and method of use |
| KR20180084104A (ko) | 2015-11-20 | 2018-07-24 | 포사이트 비젼4, 인크. | 연장 방출 약물 전달 장치를 위한 다공성 구조물 |
| JP7009384B2 (ja) | 2016-04-05 | 2022-01-25 | フォーサイト・ビジョン フォー・インコーポレーテッド | 移植可能な眼薬送達デバイス |
| KR20200093581A (ko) | 2017-11-21 | 2020-08-05 | 포사이트 비젼4, 인크. | 확장 가능한 포트 전달 시스템을 위한 유체 교환 기기 및 사용 방법 |
| USD1033637S1 (en) | 2022-01-24 | 2024-07-02 | Forsight Vision4, Inc. | Fluid exchange device |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4923892A (en) | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| GB8520662D0 (en) | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US4778814A (en) * | 1987-03-18 | 1988-10-18 | Ciba-Geigy Corporation | Method of treating ocular allergy by topical application of a 2-substituted-1,2-benzisoselenazol-3(2H)-one |
| US5192780A (en) * | 1989-12-18 | 1993-03-09 | Alcon Laboratories, Inc. | Methods using antiallergics and antihistamines |
| AU636685B2 (en) | 1989-12-18 | 1993-05-06 | Alcon Laboratories, Inc. | Compositions of antiallergics and antihistamines and methods for their use |
| US5641805A (en) | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| JP2001518118A (ja) | 1997-03-25 | 2001-10-09 | アレゲニー ユニバーシティー オブ ザ ヘルス サイエンシズ | ヒト肥満細胞活性化のモジュレーション |
| EP1014979A4 (en) | 1997-06-09 | 2003-08-20 | Bridge Pharma Inc | CONNECTIONS WITH COMBINED ANTIHISTAMINIC AND FAST-CELL STABILIZING ACTIVITY FOR OPHTHALMOLOGICAL USE |
| JP2002520355A (ja) | 1998-07-14 | 2002-07-09 | アルコン ラボラトリーズ， インコーポレイテッド | 非アレルギー性眼炎症障害を処置および眼新生血管形成を予防する医薬製造のための、１１−（３−ジメチルアミノプロピリデン）−６，１１−ジヒドロジベンズ［ｂ，ｅ］オキセピン−２−酢酸の使用 |
| SE9803279D0 (sv) | 1998-09-25 | 1998-09-25 | Astra Pharma Prod | Novel compounds |
-
2000
- 2000-03-16 JP JP2001504456A patent/JP4851035B2/ja not_active Expired - Fee Related
- 2000-03-16 ES ES00917998T patent/ES2213001T3/es not_active Expired - Lifetime
- 2000-03-16 US US09/527,401 patent/US6420399B1/en not_active Expired - Lifetime
- 2000-03-16 DK DK00917998T patent/DK1187617T3/da active
- 2000-03-16 EP EP00917998A patent/EP1187617B1/en not_active Expired - Lifetime
- 2000-03-16 PT PT00917998T patent/PT1187617E/pt unknown
- 2000-03-16 AU AU38883/00A patent/AU770975B2/en not_active Ceased
- 2000-03-16 AT AT00917998T patent/ATE260660T1/de active
- 2000-03-16 CA CA002374002A patent/CA2374002A1/en not_active Abandoned
- 2000-03-16 WO PCT/US2000/006890 patent/WO2000078396A2/en not_active Ceased
- 2000-03-16 DE DE60008730T patent/DE60008730T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT1187617E (pt) | 2004-06-30 |
| EP1187617A2 (en) | 2002-03-20 |
| JP2003502393A (ja) | 2003-01-21 |
| EP1187617B1 (en) | 2004-03-03 |
| ES2213001T3 (es) | 2004-08-16 |
| AU770975B2 (en) | 2004-03-11 |
| WO2000078396A3 (en) | 2001-08-16 |
| DE60008730T2 (de) | 2004-08-05 |
| DE60008730D1 (de) | 2004-04-08 |
| ATE260660T1 (de) | 2004-03-15 |
| US6420399B1 (en) | 2002-07-16 |
| AU3888300A (en) | 2001-01-09 |
| CA2374002A1 (en) | 2000-12-28 |
| WO2000078396A2 (en) | 2000-12-28 |
| JP4851035B2 (ja) | 2012-01-11 |
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