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DK1165478T3 - Fremgangsmåde til syntetisering af sevofluran og et mellemprodukt deraf - Google Patents

Fremgangsmåde til syntetisering af sevofluran og et mellemprodukt deraf

Info

Publication number
DK1165478T3
DK1165478T3 DK00918331T DK00918331T DK1165478T3 DK 1165478 T3 DK1165478 T3 DK 1165478T3 DK 00918331 T DK00918331 T DK 00918331T DK 00918331 T DK00918331 T DK 00918331T DK 1165478 T3 DK1165478 T3 DK 1165478T3
Authority
DK
Denmark
Prior art keywords
sevochlorane
produce
synthesizing
fluoromethyl
synthesizing sevoflurane
Prior art date
Application number
DK00918331T
Other languages
English (en)
Inventor
Christopher Bieniarz
Christopher Behme
Kornepati V Ramakrishna
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1165478T3 publication Critical patent/DK1165478T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • General Preparation And Processing Of Foods (AREA)
DK00918331T 1999-03-26 2000-03-24 Fremgangsmåde til syntetisering af sevofluran og et mellemprodukt deraf DK1165478T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/280,794 US6100434A (en) 1999-03-26 1999-03-26 Method for synthesizing sevoflurane and an intermediate thereof

Publications (1)

Publication Number Publication Date
DK1165478T3 true DK1165478T3 (da) 2005-11-07

Family

ID=23074683

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00918331T DK1165478T3 (da) 1999-03-26 2000-03-24 Fremgangsmåde til syntetisering af sevofluran og et mellemprodukt deraf

Country Status (11)

Country Link
US (1) US6100434A (da)
EP (1) EP1165478B1 (da)
JP (1) JP2002540179A (da)
AT (1) ATE299486T1 (da)
AU (1) AU773249B2 (da)
CA (1) CA2366673A1 (da)
DE (1) DE60021258T2 (da)
DK (1) DK1165478T3 (da)
ES (1) ES2246842T3 (da)
PT (1) PT1165478E (da)
WO (1) WO2000058251A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245949B1 (en) * 2000-06-01 2001-06-12 Abbott Laboratories Synthetic method for the fluoromethylation of alcohols
US6271422B1 (en) * 2000-06-01 2001-08-07 Abbott Laboratories Method for fluoromethylation of alcohols via halogenative decarboxylation
WO2004065340A1 (en) * 2003-01-14 2004-08-05 Baxter International Inc. Process for recovery of 1,1,1,3,3,3-hexafluoroisopropanol from the waste stream of sevoflurane synthesis
PL1812368T3 (pl) * 2004-11-17 2013-07-31 Piramal Critical Care Inc Sposób wytwarzania sewofluranu
CN101535231B (zh) * 2006-09-29 2012-12-19 克里斯泰利亚化学药物产品有限公司 制备氯甲基2,2,2-三氟-1-(三氟甲基)乙基醚的方法
JP5021745B2 (ja) * 2006-09-29 2012-09-12 クリスタリア プロデュトス キミコス ファーマシューティコス リミターダ フルオロメチル２，２，２−トリフロオロ−１−（トリフルオロメチル）エチルエーテルの製造方法
RU2368597C2 (ru) * 2007-08-06 2009-09-27 Закрытое акционерное общество Научно-производственное объединение "ПиМ-Инвест" Двухстадийный способ получения 2-(фторметокси)-1,1,1,3,3,3-гексафторизопропана (севофлурана)
JP5163064B2 (ja) 2007-11-13 2013-03-13 ダイキン工業株式会社 新規カルボン酸エステル、その用途及びその製造方法
US7732647B2 (en) * 2007-12-27 2010-06-08 Halocarbon Products Corporation Process for the purification of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether (sevoflurane)
CN101314560B (zh) * 2008-07-02 2011-06-15 鲁南制药集团股份有限公司 七氟烷的合成方法
WO2010079057A1 (en) * 2008-12-18 2010-07-15 Shell Internationale Research Maatschappij B.V. Multi stage process for producing hydrocarbons from syngas
WO2010096959A1 (zh) * 2009-02-25 2010-09-02 江苏恒瑞医药股份有限公司 制备氯甲基-1,1,1,3,3,3-六氟异丙基醚的方法
US8987524B2 (en) 2009-08-10 2015-03-24 Solvay Fluor Gmbh Process for the manufacture of Sevoflurane
EP2673256B1 (en) 2011-02-10 2015-04-08 Solvay SA Process for the manufacture of fluoromethoxymalonic acid derivatives
US8729313B2 (en) 2011-08-15 2014-05-20 Baxter International Inc. Process for the manufacturing of sevoflurane
EP2626341A1 (en) 2012-02-10 2013-08-14 Solvay Sa Manufacture of hexafluoroisopropanol
CN103804151A (zh) * 2012-11-07 2014-05-21 东莞市长安东阳光铝业研发有限公司 一种七氟醚的制备方法
CA3014020C (en) 2016-02-23 2021-01-05 Sagetech Medical Equipment Limited Improvements to the manufacture and remanufacture of volatile anaesthetic agents using supercritical fluids
CN108689808B (zh) * 2017-04-06 2021-11-16 江苏恒瑞医药股份有限公司 一种氯甲基六氟异丙醚的制备方法
CN108727166B (zh) * 2017-04-17 2021-06-29 江苏恒瑞医药股份有限公司 一种氯甲基六氟异丙醚的精制方法
CN107698430B (zh) * 2017-11-01 2021-01-08 华东医药（西安）博华制药有限公司 一种七氟烷反应液的后处理方法
CN110105178A (zh) * 2019-05-17 2019-08-09 华东医药（西安）博华制药有限公司 一种合成七氟烷中间体的方法
CN114057546A (zh) * 2021-05-07 2022-02-18 安徽伟祥新材料有限公司 一种3-氟-1-丙醇的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2992276A (en) * 1959-05-20 1961-07-11 Du Pont Process for preparing polyfluoro alkyl compounds
US3476860A (en) * 1966-12-08 1969-11-04 Air Reduction Halomethyl fluoroisopropyl ethers as anesthetic agents
GB1250928A (da) * 1968-10-28 1971-10-27
US3689571A (en) * 1970-07-31 1972-09-05 Baxter Laboratories Inc Fluorinated ether
US3683092A (en) * 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia
US4250334A (en) * 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4469898A (en) * 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4874901A (en) * 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
DE69708544T3 (de) * 1996-02-21 2005-02-03 Central Glass Co., Ltd., Ube Verfahren zur herstellung von fluoromethyl-(1,1,1,3,3,3)-hexafluoroisopropylether
US5969193A (en) * 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) * 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers

Also Published As

Publication number Publication date
AU3916000A (en) 2000-10-16
DE60021258D1 (de) 2005-08-18
JP2002540179A (ja) 2002-11-26
DE60021258T2 (de) 2006-04-20
WO2000058251A1 (en) 2000-10-05
EP1165478A1 (en) 2002-01-02
CA2366673A1 (en) 2000-10-05
PT1165478E (pt) 2005-11-30
AU773249B2 (en) 2004-05-20
ATE299486T1 (de) 2005-07-15
ES2246842T3 (es) 2006-03-01
EP1165478B1 (en) 2005-07-13
US6100434A (en) 2000-08-08

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