DK1163018T3 - Mineralisering og cellulær mønstring på biomaterialeoverflader - Google Patents
Mineralisering og cellulær mønstring på biomaterialeoverfladerInfo
- Publication number
- DK1163018T3 DK1163018T3 DK00921402T DK00921402T DK1163018T3 DK 1163018 T3 DK1163018 T3 DK 1163018T3 DK 00921402 T DK00921402 T DK 00921402T DK 00921402 T DK00921402 T DK 00921402T DK 1163018 T3 DK1163018 T3 DK 1163018T3
- Authority
- DK
- Denmark
- Prior art keywords
- mineralization
- patterned
- mineralized
- patterning
- biomaterial surfaces
- Prior art date
Links
- 239000012620 biological material Substances 0.000 title abstract 3
- 230000033558 biomineral tissue development Effects 0.000 title abstract 2
- 230000001413 cellular effect Effects 0.000 title abstract 2
- 238000000059 patterning Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- 230000031018 biological processes and functions Effects 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000001089 mineralizing effect Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 230000008467 tissue growth Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Prostheses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12511899P | 1999-03-19 | 1999-03-19 | |
| US16728999P | 1999-11-24 | 1999-11-24 | |
| PCT/US2000/007207 WO2000056375A2 (en) | 1999-03-19 | 2000-03-17 | Mineralization and cellular patterning on biomaterial surfaces |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1163018T3 true DK1163018T3 (da) | 2003-09-29 |
Family
ID=26823278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00921402T DK1163018T3 (da) | 1999-03-19 | 2000-03-17 | Mineralisering og cellulær mønstring på biomaterialeoverflader |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6541022B1 (da) |
| EP (1) | EP1163018B1 (da) |
| AT (1) | ATE241397T1 (da) |
| AU (1) | AU4173000A (da) |
| CA (1) | CA2370063C (da) |
| DE (1) | DE60003006T2 (da) |
| DK (1) | DK1163018T3 (da) |
| ES (1) | ES2199815T3 (da) |
| WO (1) | WO2000056375A2 (da) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7427602B1 (en) | 1998-05-13 | 2008-09-23 | The Regents Of The University Of Michigan | Sustained DNA delivery from structural matrices |
| ATE241397T1 (de) * | 1999-03-19 | 2003-06-15 | Univ Michigan | Mineralisierung und zelluläre strukturierung von biomaterialoberflächen |
| US6767928B1 (en) * | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
| WO2001035932A2 (en) * | 1999-11-18 | 2001-05-25 | The Regents Of The University Of Michigan | Sustained drug delivery from structural matrices |
| WO2002067871A2 (en) * | 2001-02-28 | 2002-09-06 | Ezaki Glico Co., Ltd. | Compositions having anti-dental caries function |
| US7354733B2 (en) * | 2001-03-29 | 2008-04-08 | Cellect Technologies Corp. | Method for sorting and separating living cells |
| US6703235B2 (en) * | 2001-06-25 | 2004-03-09 | Board Of Regents, The University Of Texas System | Complex multicellular assemblies ex vivo |
| US7247609B2 (en) * | 2001-12-18 | 2007-07-24 | Universitat Zurich | Growth factor modified protein matrices for tissue engineering |
| US6884432B2 (en) * | 2002-04-25 | 2005-04-26 | Mayo Foundation For Medical Education And Research | Blend, cross-linkable poly(propylene fumarate) for immobilization and controlled drug delivery |
| WO2004056321A2 (en) * | 2002-12-18 | 2004-07-08 | The Regents Of The University Of California | Biocompatible hydrogel bone-like composites |
| US7309232B2 (en) * | 2003-10-10 | 2007-12-18 | Dentigenix Inc. | Methods for treating dental conditions using tissue scaffolds |
| US7767221B2 (en) * | 2004-03-05 | 2010-08-03 | The Trustees Of Columbia University In The City Of New York | Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone |
| CA2557436A1 (en) * | 2004-03-05 | 2005-09-29 | The Trustees Of Columbia University In The City Of New York | Polymer-ceramic-hydrogel composite scaffold for osteochondral repair |
| US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| US8071083B2 (en) * | 2004-12-13 | 2011-12-06 | Progentix Orthobiology B.V. | Tissue regeneration |
| US8575101B2 (en) | 2005-01-06 | 2013-11-05 | Kuros Biosurgery Ag | Supplemented matrices for the repair of bone fractures |
| WO2006091653A2 (en) * | 2005-02-23 | 2006-08-31 | The Regents Of The University Of California | Flexible hydrogel-based functional composite materials |
| DE102005042707A1 (de) * | 2005-09-01 | 2007-03-08 | Polymedics Innovations Gmbh | Formkörper zur medizinischen Behandlung von Wunden |
| US8936805B2 (en) | 2005-09-09 | 2015-01-20 | Board Of Trustees Of The University Of Arkansas | Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same |
| US9763788B2 (en) | 2005-09-09 | 2017-09-19 | Board Of Trustees Of The University Of Arkansas | Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same |
| US8518123B2 (en) * | 2005-09-09 | 2013-08-27 | Board Of Trustees Of The University Of Arkansas | System and method for tissue generation and bone regeneration |
| EP1951327A2 (en) | 2005-11-17 | 2008-08-06 | Biomimetic Therapeutics, Inc. | Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix |
| US8067237B2 (en) | 2005-12-13 | 2011-11-29 | President And Fellows Of Harvard College | Scaffolds for cell transplantation |
| EP1991282B1 (en) * | 2006-02-09 | 2013-06-19 | BioMimetic Therapeutics, LLC | Compositions and methods for treating bone |
| KR100829452B1 (ko) * | 2006-06-13 | 2008-05-15 | (주)코리아 본 뱅크 | 생리활성형 단백질-인산칼슘 복합체 및 그 제조 방법 |
| US7767250B2 (en) * | 2006-06-15 | 2010-08-03 | National Research Council Of Canada | Bioceramic coating of a metal-containing substrate |
| CN100428964C (zh) * | 2006-06-29 | 2008-10-29 | 武汉理工大学 | RGD多肽接枝聚(羟基乙酸-L-赖氨酸-L-乳酸)/β-磷酸三钙复合材料及其制备方法 |
| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| US9642891B2 (en) | 2006-06-30 | 2017-05-09 | Biomimetic Therapeutics, Llc | Compositions and methods for treating rotator cuff injuries |
| US9439948B2 (en) | 2006-10-30 | 2016-09-13 | The Regents Of The University Of Michigan | Degradable cage coated with mineral layers for spinal interbody fusion |
| US8275594B2 (en) * | 2006-10-30 | 2012-09-25 | The Regents Of The University Of Michigan | Engineered scaffolds for intervertebral disc repair and regeneration and for articulating joint repair and regeneration |
| US12171904B2 (en) | 2006-10-30 | 2024-12-24 | Trs Holdings Llc | Mineral coated scaffolds |
| US10772987B2 (en) | 2006-10-30 | 2020-09-15 | Trs Holdings Llc | Mineral coated scaffolds |
| EP2462895B1 (en) | 2006-11-03 | 2016-11-02 | BioMimetic Therapeutics, LLC | Compositions and methods for arthrodetic procedures |
| US20100047309A1 (en) * | 2006-12-06 | 2010-02-25 | Lu Helen H | Graft collar and scaffold apparatuses for musculoskeletal tissue engineering and related methods |
| US20090287309A1 (en) * | 2007-01-30 | 2009-11-19 | Tornier Sas | Intra-articular joint replacement |
| FR2911773B1 (fr) | 2007-01-30 | 2009-03-27 | Tornier Sas | Methode et ensemble d'instrumentation chirurgicale pour poser une prothese totale d'epaule inversee,et prothese correspondante |
| US20080195476A1 (en) * | 2007-02-09 | 2008-08-14 | Marchese Michael A | Abandonment remarketing system |
| US8753391B2 (en) * | 2007-02-12 | 2014-06-17 | The Trustees Of Columbia University In The City Of New York | Fully synthetic implantable multi-phased scaffold |
| DE602008005987D1 (de) * | 2007-02-22 | 2011-05-19 | Corning Inc | Substrate für zellkultur und herstellungsverfahren dafür |
| US9770535B2 (en) * | 2007-06-21 | 2017-09-26 | President And Fellows Of Harvard College | Scaffolds for cell collection or elimination |
| US8075562B2 (en) * | 2007-06-25 | 2011-12-13 | Wisconsin Alumni Research Foundation | Controlled release of biopharmaceutical growth factors from hydroxyapatite coating on bioresorbable interference screws used in cruciate ligament reconstruction surgery |
| US20090286907A1 (en) * | 2008-01-23 | 2009-11-19 | Beltz Mark W | Fumaric Acid/Diol Polyesters and Their Manufacture and Use |
| AU2009212151C1 (en) * | 2008-02-07 | 2015-09-17 | Stryker Corporation | Compositions and methods for distraction osteogenesis |
| JP5690143B2 (ja) | 2008-02-13 | 2015-03-25 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 持続的細胞プログラミング装置 |
| US9370558B2 (en) | 2008-02-13 | 2016-06-21 | President And Fellows Of Harvard College | Controlled delivery of TLR agonists in structural polymeric devices |
| US9012399B2 (en) * | 2008-05-30 | 2015-04-21 | President And Fellows Of Harvard College | Controlled release of growth factors and signaling molecules for promoting angiogenesis |
| WO2010019788A1 (en) | 2008-08-13 | 2010-02-18 | Smed-Ta/Td. Llc | Drug delivery implants |
| US9700431B2 (en) | 2008-08-13 | 2017-07-11 | Smed-Ta/Td, Llc | Orthopaedic implant with porous structural member |
| US10842645B2 (en) | 2008-08-13 | 2020-11-24 | Smed-Ta/Td, Llc | Orthopaedic implant with porous structural member |
| US20100042213A1 (en) | 2008-08-13 | 2010-02-18 | Nebosky Paul S | Drug delivery implants |
| US9616205B2 (en) | 2008-08-13 | 2017-04-11 | Smed-Ta/Td, Llc | Drug delivery implants |
| WO2010025386A1 (en) | 2008-08-29 | 2010-03-04 | Smed-Ta/Td, Llc | Orthopaedic implant |
| EP2341951A2 (en) * | 2008-09-09 | 2011-07-13 | BioMimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries |
| CA2740633C (en) | 2008-09-25 | 2019-02-26 | Tissue Regeneration Systems, Inc. | Mineral-coated microspheres |
| KR20110135949A (ko) * | 2009-03-05 | 2011-12-20 | 바이오미메틱 세라퓨틱스, 인크. | 혈소판-유래 성장 인자 조성물 및 골연골성 결함의 치료 방법 |
| WO2010120749A2 (en) | 2009-04-13 | 2010-10-21 | President And Fellow Of Harvard College | Harnessing cell dynamics to engineer materials |
| US8728456B2 (en) | 2009-07-31 | 2014-05-20 | President And Fellows Of Harvard College | Programming of cells for tolerogenic therapies |
| US8492339B2 (en) * | 2009-10-26 | 2013-07-23 | Empire Technology Development Llc | Angiogenesis promoted by caged growth factors |
| CN107080834A (zh) | 2010-02-22 | 2017-08-22 | 生物模拟治疗有限责任公司 | 用于治疗腱病的血小板衍生生长因子组合物和方法 |
| EP2542230A4 (en) | 2010-03-05 | 2013-08-28 | Harvard College | PROMOTING THE ADHESION OF SKELETAL MUSCLE STEM CELLS BY SIMULTANEOUS ADMINISTRATION OF VEGF AND IGF-1 |
| US9408652B2 (en) | 2010-04-27 | 2016-08-09 | Tornier Sas | Intra-articular joint replacement and method |
| US9693954B2 (en) | 2010-06-25 | 2017-07-04 | President And Fellows Of Harvard College | Co-delivery of stimulatory and inhibitory factors to create temporally stable and spatially restricted zones |
| WO2012027218A2 (en) | 2010-08-27 | 2012-03-01 | Corning Incorporated | Peptide-modified surfaces for cell culture |
| EP3620185A1 (en) | 2010-10-06 | 2020-03-11 | President and Fellows of Harvard College | Injectable, pore-forming hydrogels for materials-based cell therapies |
| US9603894B2 (en) | 2010-11-08 | 2017-03-28 | President And Fellows Of Harvard College | Materials presenting notch signaling molecules to control cell behavior |
| WO2012105983A1 (en) * | 2011-02-03 | 2012-08-09 | Empire Technology Development Llc | Selective 3d biopatterning |
| ES2882852T3 (es) | 2011-03-16 | 2021-12-02 | Kuros Biosurgery Ag | Formulación farmacéutica para la utilización en la fusión espinal |
| US10647959B2 (en) | 2011-04-27 | 2020-05-12 | President And Fellows Of Harvard College | Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation |
| AU2012249456A1 (en) | 2011-04-28 | 2013-10-31 | President And Fellows Of Harvard College | Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| WO2012167230A1 (en) | 2011-06-03 | 2012-12-06 | President And Fellows Of Harvard College | In situ antigen-generating cancer vaccine |
| WO2012176023A1 (en) | 2011-06-23 | 2012-12-27 | Indian Institute Of Technology Kanpur | Hydrogel scaffolds for tissue engineering |
| US8753309B2 (en) | 2011-06-24 | 2014-06-17 | The Invention Science Fund I, Llc | Device, system, and method including micro-patterned cell treatment array |
| LT2838515T (lt) | 2012-04-16 | 2020-03-10 | President And Fellows Of Harvard College | Mezoporinės silico dioksido kompozicijos, skirtos imuninio atsako moduliavimui |
| WO2014169249A1 (en) | 2013-04-12 | 2014-10-16 | The Trustees Of Columbia University In The City Of New York | Methods for host cell homing and dental pulp regeneration |
| DE102013217085A1 (de) * | 2013-08-27 | 2015-03-05 | Gilupi Gmbh | Verfahren zur Verbesserung der Biokompatibilität einer Oberfläche |
| EP3137105A4 (en) | 2014-04-30 | 2017-12-27 | President and Fellows of Harvard College | Combination vaccine devices and methods of killing cancer cells |
| US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
| HK1247861A1 (zh) | 2015-01-30 | 2018-10-05 | President And Fellows Of Harvard College | 用於癌症治疗的肿瘤周围和肿瘤内部材料 |
| CA2978002A1 (en) | 2015-03-03 | 2016-09-09 | Tissue Regeneration Systems, Inc. | Mineral coated scaffolds and methods of producing such scaffolds |
| EP3280464A4 (en) | 2015-04-10 | 2018-09-26 | President and Fellows of Harvard College | Immune cell trapping devices and methods for making and using the same |
| CN115487351A (zh) | 2016-02-06 | 2022-12-20 | 哈佛学院校长同事会 | 重塑造血巢以重建免疫 |
| FI3484448T3 (fi) | 2016-07-13 | 2025-06-16 | Harvard College | Antigeenia esitteleviä solumimeettisiä tukirakenteita ja menetelmiä niiden valmistamiseksi ja käyttämiseksi |
| AU2017305345B2 (en) | 2016-08-02 | 2024-09-05 | President And Fellows Of Harvard College | Biomaterials for modulating immune responses |
| WO2018222611A1 (en) * | 2017-05-30 | 2018-12-06 | Stem Pharm, Incorporated | Visible light polymerization of polyethylene glycol (peg) hydrogels |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| EP3877748A4 (en) | 2018-11-06 | 2022-11-09 | Cellino Biotech, Inc. | Systems for cell control |
| US11747269B2 (en) | 2021-11-09 | 2023-09-05 | Warsaw Orthopedic, Inc. | Systems and methods for identifying a coating on an implant |
| US12048628B2 (en) | 2021-11-09 | 2024-07-30 | Warsaw Orthopedic, Inc. | Systems and methods of coating bone material |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4636526A (en) | 1985-02-19 | 1987-01-13 | The Dow Chemical Company | Composites of unsintered calcium phosphates and synthetic biodegradable polymers useful as hard tissue prosthetics |
| US5266480A (en) | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
| US4933185A (en) | 1986-09-24 | 1990-06-12 | Massachusetts Institute Of Technology | System for controlled release of biologically active compounds |
| US5041138A (en) | 1986-11-20 | 1991-08-20 | Massachusetts Institute Of Technology | Neomorphogenesis of cartilage in vivo from cell culture |
| CA1340581C (en) | 1986-11-20 | 1999-06-08 | Joseph P. Vacanti | Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices |
| US5804178A (en) | 1986-11-20 | 1998-09-08 | Massachusetts Institute Of Technology | Implantation of cell-matrix structure adjacent mesentery, omentum or peritoneum tissue |
| US5079600A (en) | 1987-03-06 | 1992-01-07 | Schnur Joel M | High resolution patterning on solid substrates |
| JPS63270061A (ja) | 1987-04-28 | 1988-11-08 | Hoya Corp | 無機生体材料の表面改質方法 |
| US5011691A (en) | 1988-08-15 | 1991-04-30 | Stryker Corporation | Osteogenic devices |
| US5965079A (en) * | 1995-04-25 | 1999-10-12 | 3D Systems, Inc. | Method and apparatus for making a three-dimensional object by stereolithography |
| US4996120A (en) * | 1988-12-29 | 1991-02-26 | E. I. Dupont De Nemours And Company | Holographic photopolymer compositions and elements containing a ring-opening monomer |
| DE69013764T2 (de) | 1989-06-03 | 1995-03-30 | Kanegafuchi Chemical Ind | Kontrolle der Zellanordnung. |
| US5529914A (en) * | 1990-10-15 | 1996-06-25 | The Board Of Regents The Univeristy Of Texas System | Gels for encapsulation of biological materials |
| US5558517A (en) | 1992-02-24 | 1996-09-24 | Clemson University | Polymeric prosthesis having a phosphonylated surface |
| US5491198A (en) | 1992-02-24 | 1996-02-13 | Clemson University | Process for phosphonylating the surface of an organic polymeric preform |
| US5334640A (en) * | 1992-04-08 | 1994-08-02 | Clover Consolidated, Ltd. | Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods |
| US5330799A (en) * | 1992-09-15 | 1994-07-19 | The Phscologram Venture, Inc. | Press polymerization of lenticular images |
| US5514378A (en) * | 1993-02-01 | 1996-05-07 | Massachusetts Institute Of Technology | Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures |
| DE69433723T3 (de) * | 1993-02-22 | 2008-10-30 | Abraxis Bioscience, Inc., Los Angeles | Verfahren für die in-vivo-verabreichung von biologischen substanzen und hierfür verwendbare zusammensetzungen |
| CA2160878A1 (en) | 1993-04-19 | 1994-10-27 | Sandra Gertrude Mcelligott | Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression |
| US5876454A (en) * | 1993-05-10 | 1999-03-02 | Universite De Montreal | Modified implant with bioactive conjugates on its surface for improved integration |
| US5776748A (en) | 1993-10-04 | 1998-07-07 | President And Fellows Of Harvard College | Method of formation of microstamped patterns on plates for adhesion of cells and other biological materials, devices and uses therefor |
| US5512131A (en) | 1993-10-04 | 1996-04-30 | President And Fellows Of Harvard College | Formation of microstamped patterns on surfaces and derivative articles |
| WO1995019796A1 (en) * | 1994-01-21 | 1995-07-27 | Brown University Research Foundation | Biocompatible implants |
| US5763416A (en) | 1994-02-18 | 1998-06-09 | The Regent Of The University Of Michigan | Gene transfer into bone cells and tissues |
| US5962427A (en) | 1994-02-18 | 1999-10-05 | The Regent Of The University Of Michigan | In vivo gene transfer methods for wound healing |
| US5942496A (en) | 1994-02-18 | 1999-08-24 | The Regent Of The University Of Michigan | Methods and compositions for multiple gene transfer into bone cells |
| CA2147813A1 (en) | 1994-04-28 | 1995-10-29 | Richard Dixon | Intravascular prosthesis with anti-thrombogenic coating |
| US5807406A (en) * | 1994-10-07 | 1998-09-15 | Baxter International Inc. | Porous microfabricated polymer membrane structures |
| US5641391A (en) * | 1995-05-15 | 1997-06-24 | Hunter; Ian W. | Three dimensional microfabrication by localized electrodeposition and etching |
| US5654381A (en) | 1995-06-16 | 1997-08-05 | Massachusetts Institute Of Technology | Functionalized polyester graft copolymers |
| US5965125A (en) * | 1995-10-25 | 1999-10-12 | Transkaryotic Therapies, Inc. | Hybrid matrix implants and explants |
| EP0862616B1 (en) | 1995-11-06 | 2008-07-30 | Mount Sinai Hospital | Reconstituted mineralized cartilage tissue |
| US5830539A (en) * | 1995-11-17 | 1998-11-03 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Methods for functionalizing and coating substrates and devices made according to the methods |
| US6033719A (en) | 1996-04-25 | 2000-03-07 | Medtronic, Inc. | Method for covalent attachment of biomolecules to surfaces of medical devices |
| US5785965A (en) | 1996-05-15 | 1998-07-28 | The Board Of Trustees Of The Leland Stanford Junior Univ. | VEGF gene transfer into endothelial cells for vascular prosthesis |
| EP0915967A1 (en) | 1996-05-28 | 1999-05-19 | The Board Of Regents Of The University Of Michigan | Engineering oral tissues |
| US5855802A (en) | 1996-05-30 | 1999-01-05 | International Business Machines Corporation | Method and apparatus for forming a tubular article having a perforated annular wall |
| US6143037A (en) | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
| US6210707B1 (en) * | 1996-11-12 | 2001-04-03 | The Regents Of The University Of California | Methods of forming protein-linked lipidic microparticles, and compositions thereof |
| WO1998041189A1 (en) * | 1997-03-20 | 1998-09-24 | Therics, Inc. | Fabrication of tissue products using a mold formed by solid free-form methods |
| WO1998044027A1 (en) | 1997-03-31 | 1998-10-08 | The Regents Of The University Of Michigan | Open pore biodegradable matrices |
| WO1999001538A1 (en) * | 1997-07-03 | 1999-01-14 | Massachusetts Institute Of Technology | Tissue-engineered constructs |
| EP0891783B1 (en) * | 1997-07-16 | 2002-06-12 | IsoTis N.V. | Device for tissue engineering bone comprising biodegradable thermoplastic copolyester and cultured cells |
| US6077987A (en) * | 1997-09-04 | 2000-06-20 | North Shore-Long Island Jewish Research Institute | Genetic engineering of cells to enhance healing and tissue regeneration |
| US6391311B1 (en) | 1998-03-17 | 2002-05-21 | Genentech, Inc. | Polypeptides having homology to vascular endothelial cell growth factor and bone morphogenetic protein 1 |
| US5925069A (en) * | 1997-11-07 | 1999-07-20 | Sulzer Intermedics Inc. | Method for preparing a high definition window in a conformally coated medical device |
| US6187329B1 (en) | 1997-12-23 | 2001-02-13 | Board Of Regents Of The University Of Texas System | Variable permeability bone implants, methods for their preparation and use |
| WO1999044538A1 (en) | 1998-01-27 | 1999-09-10 | The Regents Of The University Of California | Biodegradable polymer/protein based coils for intralumenal implants |
| JP2002511496A (ja) * | 1998-04-13 | 2002-04-16 | マサチューセッツ インスティテュート オブ テクノロジー | 細胞表面相互作用を調節するためのコームコポリマー |
| AU3898699A (en) | 1998-05-13 | 1999-11-29 | Regents Of The University Of Michigan, The | Sustained dna delivery from structural matrices |
| US6767928B1 (en) * | 1999-03-19 | 2004-07-27 | The Regents Of The University Of Michigan | Mineralization and biological modification of biomaterial surfaces |
| ATE241397T1 (de) * | 1999-03-19 | 2003-06-15 | Univ Michigan | Mineralisierung und zelluläre strukturierung von biomaterialoberflächen |
| US6200646B1 (en) * | 1999-08-25 | 2001-03-13 | Spectra Group Limited, Inc. | Method for forming polymeric patterns, relief images and colored polymeric bodies using digital light processing technology |
-
2000
- 2000-03-17 AT AT00921402T patent/ATE241397T1/de not_active IP Right Cessation
- 2000-03-17 DE DE60003006T patent/DE60003006T2/de not_active Expired - Lifetime
- 2000-03-17 AU AU41730/00A patent/AU4173000A/en not_active Abandoned
- 2000-03-17 ES ES00921402T patent/ES2199815T3/es not_active Expired - Lifetime
- 2000-03-17 US US09/527,638 patent/US6541022B1/en not_active Expired - Fee Related
- 2000-03-17 CA CA2370063A patent/CA2370063C/en not_active Expired - Lifetime
- 2000-03-17 WO PCT/US2000/007207 patent/WO2000056375A2/en not_active Ceased
- 2000-03-17 EP EP00921402A patent/EP1163018B1/en not_active Expired - Lifetime
- 2000-03-17 DK DK00921402T patent/DK1163018T3/da active
-
2003
- 2003-03-31 US US10/403,250 patent/US20030203002A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1163018B1 (en) | 2003-05-28 |
| US6541022B1 (en) | 2003-04-01 |
| EP1163018A2 (en) | 2001-12-19 |
| ATE241397T1 (de) | 2003-06-15 |
| DE60003006T2 (de) | 2004-04-01 |
| WO2000056375A3 (en) | 2001-01-11 |
| AU4173000A (en) | 2000-10-09 |
| CA2370063A1 (en) | 2000-09-28 |
| US20030203002A1 (en) | 2003-10-30 |
| WO2000056375A2 (en) | 2000-09-28 |
| DE60003006D1 (de) | 2003-07-03 |
| CA2370063C (en) | 2012-10-02 |
| ES2199815T3 (es) | 2004-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1163018T3 (da) | Mineralisering og cellulær mønstring på biomaterialeoverflader | |
| DE50005034D1 (de) | Resorbierbares knochenersatz- und knochenaufbaumaterial | |
| ATE296642T1 (de) | Reverse-phase zusamensetzung zur bindegewebsreparatur | |
| AU2002307791A1 (en) | Composite scaffolds and methods using same for generating complex tissue grafts | |
| DE69727332D1 (de) | Zubereitungen enthaltend Kollagen, Vitamin D3 und Kalzium zur Verstärkung des Knochens | |
| EP1148847A4 (en) | COMPOSITE BONE GRAFT, METHOD OF MANUFACTURE AND USE THEREOF | |
| WO2003011184A8 (en) | Adventitial fabric reinforced porous prosthetic graft | |
| WO2001054746A3 (en) | Composite biomaterial including anisometric calcium phosphate reinforcement particles | |
| EP1082057A4 (en) | BIOLOGICALLY MODELED IMPLANTABLE PROSTHESIS | |
| DE60041332D1 (de) | Implantat | |
| DE69824092D1 (de) | Prothese zur Hernia Reparatur | |
| ATE270078T1 (de) | Knochentransplantatmatrix | |
| DE69940504D1 (da) | ||
| WO2000045867A8 (en) | Implant comprising calcium cement and hydrophobic liquid | |
| ATE252134T1 (de) | Bioaktives verbundmaterial zum reparieren von hartem und weichem gewebe | |
| DE69703547D1 (de) | Dauerhafte, niedrige oberflächenenergie aufweisende verbindungen und gegenstände, vorrichtungen und verfahren zur verwendung davon | |
| DE69940507D1 (de) | Biotechnisch erzeugte gefässprothese für die implantation | |
| ATE223486T1 (de) | Bmp-9 zusammensetzungen | |
| DE60137096D1 (de) | Zusammensetzung zur Unterbindung von Körpergeruch und Verwendung derselben | |
| AU2001255453A1 (en) | Polylactide/dextran graft co-polymers for biomaterial and tissue engineering applications | |
| EP1220272A4 (en) | SOURCE OF BEAMS | |
| AR016981A2 (es) | Polipeptidos sinteticos | |
| EP1277482A3 (en) | Mineralization and cellular patterning on biomaterial surfaces | |
| DE68913991D1 (de) | Implantat zur verwendung in der knochenchirurgie. | |
| DE69920504D1 (de) | Vorrichtung zur bildaufzeichnung von gewebe |