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DK1161225T3 - Dosing aerosol with isobutane as propellant - Google Patents

Dosing aerosol with isobutane as propellant

Info

Publication number
DK1161225T3
DK1161225T3 DK00906289T DK00906289T DK1161225T3 DK 1161225 T3 DK1161225 T3 DK 1161225T3 DK 00906289 T DK00906289 T DK 00906289T DK 00906289 T DK00906289 T DK 00906289T DK 1161225 T3 DK1161225 T3 DK 1161225T3
Authority
DK
Denmark
Prior art keywords
isobutane
propellant
dosing aerosol
broncholytic
aerosol
Prior art date
Application number
DK00906289T
Other languages
Danish (da)
Inventor
Franz Guck
Gieselher Warnke
Original Assignee
Ig Spruehtechnik Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Spruehtechnik Gmbh & Co Kg filed Critical Ig Spruehtechnik Gmbh & Co Kg
Application granted granted Critical
Publication of DK1161225T3 publication Critical patent/DK1161225T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to metered dose inhalers with broncholytic active agents and isobutane that has been liquefied under pressure as the propellant. The broncholytic active agent is selected from the group of glucocorticoids or the derivatives thereof.
DK00906289T 1999-03-12 2000-02-07 Dosing aerosol with isobutane as propellant DK1161225T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19911064A DE19911064A1 (en) 1999-03-12 1999-03-12 MDIs with isobutane as propellant
PCT/EP2000/000946 WO2000054748A1 (en) 1999-03-12 2000-02-07 Metered dose inhalers with isobutane as propellant

Publications (1)

Publication Number Publication Date
DK1161225T3 true DK1161225T3 (en) 2005-02-07

Family

ID=7900747

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00906289T DK1161225T3 (en) 1999-03-12 2000-02-07 Dosing aerosol with isobutane as propellant

Country Status (11)

Country Link
EP (1) EP1161225B1 (en)
CN (1) CN1343116A (en)
AT (1) ATE278388T1 (en)
DE (2) DE19911064A1 (en)
DK (1) DK1161225T3 (en)
ES (1) ES2230066T3 (en)
MY (1) MY125374A (en)
NO (1) NO20014406D0 (en)
PT (1) PT1161225E (en)
TW (1) TWI222881B (en)
WO (1) WO2000054748A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10161368A1 (en) * 2001-12-14 2003-07-10 Messer Griesheim Gmbh Cryogenic cooling of aerosol product mixtures, especially for filling pharmaceutical dosed aerosols, comprises controlled thermal contact with vaporized cooling gas in heat exchanger
DE10260882B4 (en) * 2002-12-24 2007-02-08 IG Sprühtechnik GmbH & Co. KG Metered aerosols with soy lecithin as a surface-active substance and its use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292499A (en) * 1990-09-11 1994-03-08 University Of Wales College Of Cardiff Method of preparing medical aerosol formulations including drug dissolved in reverse micelles
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
GB9118830D0 (en) * 1991-09-03 1991-10-16 Minnesota Mining & Mfg Medical aerosol formulations
DE4132176C2 (en) * 1991-09-27 1997-03-13 Ig Spruehtechnik Gmbh Metered aerosols with isobutane as propellant
US5202110A (en) * 1992-01-22 1993-04-13 Virginia Commonwealth University Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants

Also Published As

Publication number Publication date
NO20014406L (en) 2001-09-11
TWI222881B (en) 2004-11-01
ES2230066T3 (en) 2005-05-01
CN1343116A (en) 2002-04-03
ATE278388T1 (en) 2004-10-15
EP1161225A1 (en) 2001-12-12
WO2000054748A1 (en) 2000-09-21
PT1161225E (en) 2005-02-28
EP1161225B1 (en) 2004-10-06
DE19911064A1 (en) 2000-09-14
DE50008113D1 (en) 2004-11-11
MY125374A (en) 2006-07-31
NO20014406D0 (en) 2001-09-11

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