[go: up one dir, main page]

DK1152765T3 - Ethanolat af azithromycin, fremgangsmåde til fremstilling og farmaceutiske sammensætninger deraf - Google Patents

Ethanolat af azithromycin, fremgangsmåde til fremstilling og farmaceutiske sammensætninger deraf

Info

Publication number
DK1152765T3
DK1152765T3 DK99965069T DK99965069T DK1152765T3 DK 1152765 T3 DK1152765 T3 DK 1152765T3 DK 99965069 T DK99965069 T DK 99965069T DK 99965069 T DK99965069 T DK 99965069T DK 1152765 T3 DK1152765 T3 DK 1152765T3
Authority
DK
Denmark
Prior art keywords
ethanolate
azithromycin
preparation
pharmaceutical compositions
pharmaceutical
Prior art date
Application number
DK99965069T
Other languages
English (en)
Inventor
Claude Singer
Judith Aronhime
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22332273&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1152765(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of DK1152765T3 publication Critical patent/DK1152765T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK99965069T 1998-11-30 1999-11-30 Ethanolat af azithromycin, fremgangsmåde til fremstilling og farmaceutiske sammensætninger deraf DK1152765T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11029898P 1998-11-30 1998-11-30
EP99965069A EP1152765B1 (en) 1998-11-30 1999-11-30 Ethanolate of azithromycin, process for manufacture, and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
DK1152765T3 true DK1152765T3 (da) 2005-01-31

Family

ID=22332273

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99965069T DK1152765T3 (da) 1998-11-30 1999-11-30 Ethanolat af azithromycin, fremgangsmåde til fremstilling og farmaceutiske sammensætninger deraf

Country Status (26)

Country Link
US (1) US6365574B2 (da)
EP (2) EP1152765B1 (da)
JP (1) JP2002531409A (da)
KR (1) KR100603226B1 (da)
CN (2) CN100339384C (da)
AP (1) AP1709A (da)
AT (1) ATE279200T1 (da)
AU (1) AU768219B2 (da)
BG (1) BG105547A (da)
CA (1) CA2352562A1 (da)
CZ (1) CZ20011886A3 (da)
DE (1) DE69921192T2 (da)
DK (1) DK1152765T3 (da)
ES (1) ES2229804T3 (da)
HK (1) HK1043725B (da)
HU (1) HUP0104241A3 (da)
IL (1) IL143376A0 (da)
LV (1) LV12735B (da)
NZ (1) NZ512496A (da)
PL (1) PL197894B1 (da)
PT (1) PT1152765E (da)
RO (1) RO121408B1 (da)
RU (1) RU2240124C2 (da)
SI (1) SI20639A (da)
WO (1) WO2000032203A1 (da)
ZA (1) ZA200104312B (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20020231A2 (en) * 2002-03-18 2003-12-31 Pliva D D ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A
TW546302B (en) * 1998-05-08 2003-08-11 Biochemie Sa Improvements in macrolide production
CA2245398C (en) 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
CN100339384C (zh) * 1998-11-30 2007-09-26 特瓦制药工业有限公司 阿齐霉素的乙醇化物，制备方法以及医药组合物
CN100341886C (zh) * 2000-11-27 2007-10-10 桑多斯股份公司 大环内酯类化合物的溶剂化物
HU229488B1 (hu) * 2000-11-27 2014-01-28 Sandoz Ag Eljárás makrolid hidrátok elõállítására
KR100431431B1 (ko) * 2001-04-25 2004-05-14 한미약품 주식회사 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물
US6861413B2 (en) 2001-05-22 2005-03-01 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
GEP20084399B (en) 2001-05-22 2008-06-10 Pfizer Prod Inc Crystal forms of azithromycin
EP1652851A1 (en) 2001-05-22 2006-05-03 Pfizer Products Inc. New crystal form of Azithromycin
EP1541134A3 (en) * 2001-10-18 2007-06-06 Teva Pharmaceutical Industries Limited Stabilized azithromycin compositions
IL161398A0 (en) * 2001-10-18 2004-09-27 Teva Pharma Stabilized azithromycin compositions
US20080149521A9 (en) * 2001-10-18 2008-06-26 Michael Pesachovich Methods of stabilizing azithromycin
AU2002353316A1 (en) * 2001-12-21 2003-07-09 Pfizer Products Inc. Methods for wet granulating azithromycin
WO2003053416A1 (en) * 2001-12-21 2003-07-03 Pfizer Products Inc. Directly compressible formulations of azithromycin
RU2283092C2 (ru) * 2002-02-01 2006-09-10 Пфайзер Продактс Инк. Сухие гранулированные композиции азитромицина
HRP20020614A2 (en) * 2002-07-22 2004-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
US20050101547A1 (en) * 2003-11-06 2005-05-12 Sadatrezaei Mohsen Stabilized azithromycin composition
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
ATE399536T1 (de) * 2003-12-04 2008-07-15 Pfizer Prod Inc Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten
EP1689368B1 (en) * 2003-12-04 2016-09-28 Bend Research, Inc Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions
EP1691786A1 (en) * 2003-12-04 2006-08-23 Pfizer Products Inc. Multiparticulate compositions with improved stability
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
AU2004294818A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Azithromycin multiparticulate dosage forms by liquid-based processes
US7943585B2 (en) 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US7683162B2 (en) * 2004-08-30 2010-03-23 Taro Pharmaceutical Industries Limited Process of preparing a crystalline azithromycin monohydrate
US20100048498A1 (en) * 2004-12-21 2010-02-25 Johnson Barbara A Stable non-dihydrate azithromycin oral suspensions
US20060198895A1 (en) * 2005-03-07 2006-09-07 Kotliar Eleonora M Azithromycin powder for oral suspension compositions
US20090318375A1 (en) * 2005-06-08 2009-12-24 Hanmi Pharm Co., Ltd Crystalline Azithromycin L-Malate Monohydrate and Pharmaceutical Composition Containing Same
KR20120004448A (ko) 2009-03-13 2012-01-12 다 볼떼라 그람음성 박테리아 제거용 조성물 및 방법
EP3366326A1 (en) * 2009-04-17 2018-08-29 Micell Technologies, Inc. Stents having controlled elution
WO2013088274A1 (en) 2011-12-14 2013-06-20 Wockhardt Limited Anhydrous amorphous azithromycin composition free of azithromycin dihydrate
CN103983730B (zh) * 2014-06-11 2015-09-30 北京市药品检验所 阿奇霉素或其制剂中的杂质检查方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43006B (en) 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
RU2066324C1 (ru) * 1987-07-09 1996-09-10 Пфайзер Инк. Кристаллический дигидрат азитромицина и способ его получения
WO1989002271A1 (en) * 1987-09-10 1989-03-23 Pfizer Azithromycin and derivatives as antiprotozoal agents
CN1093370A (zh) 1993-12-10 1994-10-12 北京市集才药物研究所 一种新的阿齐红霉素结晶及其制备方法
CN1161971A (zh) * 1997-01-03 1997-10-15 石家庄制药集团有限公司 一种阿齐霉素结晶及其制备方法
CA2245398C (en) * 1998-08-21 2002-01-29 Apotex Inc. Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof
CN100339384C (zh) * 1998-11-30 2007-09-26 特瓦制药工业有限公司 阿齐霉素的乙醇化物，制备方法以及医药组合物
KR100491183B1 (ko) * 2001-03-21 2005-05-25 한미약품 주식회사 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물
GEP20084399B (en) * 2001-05-22 2008-06-10 Pfizer Prod Inc Crystal forms of azithromycin

Also Published As

Publication number Publication date
KR20010099806A (ko) 2001-11-09
CN1273142C (zh) 2006-09-06
RU2240124C2 (ru) 2004-11-20
EP1152765A4 (en) 2002-07-17
HK1043725A1 (en) 2002-09-27
EP1484062A1 (en) 2004-12-08
KR100603226B1 (ko) 2006-08-28
DE69921192T2 (de) 2006-02-16
AP2001002183A0 (en) 2001-06-30
AU768219B2 (en) 2003-12-04
PT1152765E (pt) 2004-12-31
SI20639A (sl) 2002-02-28
JP2002531409A (ja) 2002-09-24
CN1334735A (zh) 2002-02-06
US6365574B2 (en) 2002-04-02
EP1152765A1 (en) 2001-11-14
HUP0104241A2 (hu) 2002-03-28
WO2000032203A1 (en) 2000-06-08
HK1043725B (en) 2005-05-06
HUP0104241A3 (en) 2003-12-29
CZ20011886A3 (cs) 2001-10-17
PL197894B1 (pl) 2008-05-30
ZA200104312B (en) 2001-11-28
CN100339384C (zh) 2007-09-26
LV12735A (en) 2001-10-20
AP1709A (en) 2007-02-27
BG105547A (en) 2001-12-31
AU3106500A (en) 2000-06-19
PL347971A1 (en) 2002-05-06
NZ512496A (en) 2003-02-28
DE69921192D1 (de) 2004-11-18
EP1152765B1 (en) 2004-10-13
CN1737008A (zh) 2006-02-22
LV12735B (en) 2002-03-20
RO121408B1 (ro) 2007-05-30
IL143376A0 (en) 2002-04-21
US20020007049A1 (en) 2002-01-17
CA2352562A1 (en) 2000-06-08
ATE279200T1 (de) 2004-10-15
ES2229804T3 (es) 2005-04-16

Similar Documents

Publication Publication Date Title
DK1152765T3 (da) Ethanolat af azithromycin, fremgangsmåde til fremstilling og farmaceutiske sammensætninger deraf
DK0985697T3 (da) Oxiranderivater og fremgangsmåde til fremstilling deraf
EE200000791A (et) Uudsed atsüülpseudopeptiidid, nende valmistamise meetod ja neid sisaldavad farmatseutilised kompositsioonid
DK1275387T3 (da) Fremgangsmåde til fremstilling af farmaceutiske præparater af fenofibrat med höj biologisk tilgængelighed
IS5747A (is) Oxazólidínón afleiður, aðferð fyrir framleiðslu þeirra og lyfjasamsetninga sem innihalda þær
DK0980240T3 (da) Sammensætninger med lang frigivelse og fremgangsmåde til fremstilling heraf
NO20004741L (no) Farmasöytiske blandinger for forlenget peptidfrigjöring og fremstillingsmetode
PT1066027E (pt) Composicao farmaceutica de topiramato
DK1180518T3 (da) 5-pyridyl-1,3-azolforbindelser, fremgangsmåde til fremstilling deraf og anvendelse deraf
DK1044969T3 (da) Fremgangsmåde og mellemprodukter til fremstilling af anti-cancer forbindelser
NO20016277L (no) Systemer og fremgangsmåter for aerolisering av farmasöytiske sammensetninger
DK1032565T3 (da) Fremgangsmåde til fremstilling af derivater af taxoid-klassen
NO20016038L (no) Benzenderivater, fremgangsmåte for deres fremstilling og farmasöytiske preparater inneholdende de samme
EP1093448A4 (en) METHOD FOR PRODUCING CERAMIC FOAMS
DK1277724T3 (da) Fremgangsmåde til fremstilling af monofluormethylethere
DK1383733T3 (da) Fremgangsmåde til fremstilling af 1,3-substituerede indener og aryl-sammenföjede azapolycykliske forbindelser
DK1140824T3 (da) Fremgangsmåde til fremstilling af 3-alkanoyl- og 3-alkylindoler
IS6677A (is) Amínóalkýlbensóýl-bensófúran eða bensóþíófenafleiður, aðferð til framleiðslu þeirra og samsetningarsem innihalda þær
NO20015659D0 (no) Purinderivater, fremstillingsmetode og farmasöytiske preparater inneholdende disse
DK1054672T3 (da) Morfinsulfatmikrogranula, fremgangsmåde til fremstilling deraf og farmaceutiske præparater
DK1049721T3 (da) Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske præparater indeholdende disse
DK0719775T3 (da) Substituerede derivater af 4-phenylthiazol, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger, der inde
DK0735042T3 (da) Maltitolsammensætning og fremgangsmåde til fremstilling deraf
NO20013735L (no) Fremgangsmåte til fremstilling av di-iso-butaner, di-iso- butener og di-n-butener fra feltbutaner
DK1171444T3 (da) Pyridothienodiazepiner, fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse