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DK1144395T3 - 2-amino-benzoxazinon-derivater til behandling af fedme - Google Patents

2-amino-benzoxazinon-derivater til behandling af fedme

Info

Publication number
DK1144395T3
DK1144395T3 DK00900081T DK00900081T DK1144395T3 DK 1144395 T3 DK1144395 T3 DK 1144395T3 DK 00900081 T DK00900081 T DK 00900081T DK 00900081 T DK00900081 T DK 00900081T DK 1144395 T3 DK1144395 T3 DK 1144395T3
Authority
DK
Denmark
Prior art keywords
obesity
amino
treatment
benzoxazinone derivatives
benzoxazinone
Prior art date
Application number
DK00900081T
Other languages
English (en)
Inventor
Christopher Robert Dunk
Richard M J Palmer
Harold Francis Hodson
Robert Downham
Timothy J Mitchell
Beverley Jane Carr
Original Assignee
Alizyme Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alizyme Therapeutics Ltd filed Critical Alizyme Therapeutics Ltd
Application granted granted Critical
Publication of DK1144395T3 publication Critical patent/DK1144395T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/58—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK00900081T 1999-01-08 2000-01-06 2-amino-benzoxazinon-derivater til behandling af fedme DK1144395T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9900416.0A GB9900416D0 (en) 1999-01-08 1999-01-08 Inhibitors
PCT/GB2000/000031 WO2000040569A1 (en) 1999-01-08 2000-01-06 2-amino-benzoxazinone derivatives for the treatment of obesity

Publications (1)

Publication Number Publication Date
DK1144395T3 true DK1144395T3 (da) 2005-08-15

Family

ID=10845777

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00900081T DK1144395T3 (da) 1999-01-08 2000-01-06 2-amino-benzoxazinon-derivater til behandling af fedme

Country Status (21)

Country Link
US (2) US6656934B2 (da)
EP (1) EP1144395B1 (da)
JP (1) JP2002534419A (da)
KR (1) KR100615914B1 (da)
CN (1) CN100480245C (da)
AR (1) AR022203A1 (da)
AT (1) ATE293610T1 (da)
AU (1) AU770342B2 (da)
CA (1) CA2359987C (da)
DE (1) DE60019556T2 (da)
DK (1) DK1144395T3 (da)
ES (1) ES2240051T3 (da)
GB (1) GB9900416D0 (da)
HU (1) HUP0104909A3 (da)
MY (1) MY129247A (da)
NO (1) NO321058B1 (da)
NZ (1) NZ512739A (da)
PL (1) PL350412A1 (da)
PT (1) PT1144395E (da)
RU (1) RU2244711C2 (da)
WO (1) WO2000040569A1 (da)

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RU2244711C2 (ru) 2005-01-20
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HUP0104909A2 (hu) 2002-04-29
EP1144395A1 (en) 2001-10-17
US7776853B2 (en) 2010-08-17
WO2000040569A9 (en) 2002-02-28
CA2359987A1 (en) 2000-07-13
NO321058B1 (no) 2006-03-06
HUP0104909A3 (en) 2004-11-29
DE60019556D1 (de) 2005-05-25
US6656934B2 (en) 2003-12-02
KR100615914B1 (ko) 2006-08-28
CA2359987C (en) 2008-03-25
PT1144395E (pt) 2005-08-31
NZ512739A (en) 2003-10-31
ES2240051T3 (es) 2005-10-16
CN100480245C (zh) 2009-04-22
AR022203A1 (es) 2002-09-04
NO20013380D0 (no) 2001-07-06
KR20010108073A (ko) 2001-12-07
US20030013707A1 (en) 2003-01-16
AU770342B2 (en) 2004-02-19
DE60019556T2 (de) 2006-02-23
HK1047284A1 (zh) 2003-02-14
ATE293610T1 (de) 2005-05-15
US20030191123A1 (en) 2003-10-09
JP2002534419A (ja) 2002-10-15
AU1884500A (en) 2000-07-24
GB9900416D0 (en) 1999-02-24
MY129247A (en) 2007-03-30
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NO20013380L (no) 2001-09-07
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