DK1144006T3 - Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertil - Google Patents
Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertilInfo
- Publication number
- DK1144006T3 DK1144006T3 DK99966466T DK99966466T DK1144006T3 DK 1144006 T3 DK1144006 T3 DK 1144006T3 DK 99966466 T DK99966466 T DK 99966466T DK 99966466 T DK99966466 T DK 99966466T DK 1144006 T3 DK1144006 T3 DK 1144006T3
- Authority
- DK
- Denmark
- Prior art keywords
- hiv
- antibodies
- preparations
- fusion
- binding
- Prior art date
Links
- 241000713772 Human immunodeficiency virus 1 Species 0.000 title 1
- 230000004927 fusion Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000002195 synergetic effect Effects 0.000 title 1
- 239000012634 fragment Substances 0.000 abstract 2
- 102000009410 Chemokine receptor Human genes 0.000 abstract 1
- 108050000299 Chemokine receptor Proteins 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21279398A | 1998-12-16 | 1998-12-16 | |
| US11253298P | 1998-12-16 | 1998-12-16 | |
| PCT/US1999/030345 WO2000035409A2 (en) | 1998-12-16 | 1999-12-16 | Hiv-i fusion inhibition compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1144006T3 true DK1144006T3 (da) | 2007-11-26 |
Family
ID=26810060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99966466T DK1144006T3 (da) | 1998-12-16 | 1999-12-16 | Synergistisk inhibering af HIV-1-fusion og -binding, præparater og antistoffer dertil |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP2088158A3 (da) |
| JP (1) | JP2002538771A (da) |
| AT (1) | ATE375802T1 (da) |
| AU (3) | AU773175B2 (da) |
| CA (1) | CA2355607A1 (da) |
| CY (1) | CY1107858T1 (da) |
| DE (1) | DE69937369T2 (da) |
| DK (1) | DK1144006T3 (da) |
| ES (1) | ES2296416T3 (da) |
| HK (1) | HK1041207B (da) |
| MX (1) | MXPA01006097A (da) |
| PT (1) | PT1144006E (da) |
| WO (1) | WO2000035409A2 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0847452B1 (en) | 1995-06-07 | 2009-04-01 | Progenics Pharmaceuticals, Inc. | Monoclonal antibody for inhibiting hiv-1 envelope glycoprotein mediated membrane fusion |
| US7118859B2 (en) | 1996-01-17 | 2006-10-10 | Progenics Pharmaceuticals, Inc. | Methods for inhibiting HIV-1 infection |
| AU2265701A (en) * | 1999-12-16 | 2001-06-25 | Tanox, Inc. | Anti-hiv-1 conjugates for treatment of hiv disease |
| US7138119B2 (en) * | 2000-09-15 | 2006-11-21 | Progenics Pharmaceuticals, Inc. | Compositions and methods for inhibition of HIV-1 infection |
| US20020146415A1 (en) * | 2001-04-06 | 2002-10-10 | Olson William C. | Methods for inhibiting HIV-1 infection |
| US7060273B2 (en) | 2001-04-06 | 2006-06-13 | Progenics Pharmaceuticals, Inc. | Methods for inhibiting HIV-1 infection |
| US20060078537A1 (en) * | 2001-12-21 | 2006-04-13 | Matthias Mack | Mono-and dual chemokine/cytokine constructs |
| US7122185B2 (en) | 2002-02-22 | 2006-10-17 | Progenics Pharmaceuticals, Inc. | Anti-CCR5 antibody |
| DK1478738T3 (da) * | 2002-02-22 | 2009-03-09 | Pdl Biopharma Inc | Anti-CCR5-antistof |
| TW200720289A (en) | 2005-04-01 | 2007-06-01 | Hoffmann La Roche | Antibodies against CCR5 and uses thereof |
| CN101410414A (zh) * | 2006-01-30 | 2009-04-15 | 弗·哈夫曼-拉罗切有限公司 | 用于治疗hiv的具有协同作用的组合物 |
| CA2658474A1 (en) | 2006-08-17 | 2008-02-21 | F.Hoffmann-La Roche Ag | A conjugate of an antibody against ccr5 and an antifusogenic peptide |
| TW200817438A (en) | 2006-08-17 | 2008-04-16 | Hoffmann La Roche | A conjugate of an antibody against CCR5 and an antifusogenic peptide |
| MX2009002694A (es) | 2006-09-29 | 2009-03-24 | Hoffmann La Roche | Anticuerpos dirigidos contra ccr5 y usos de los mismos. |
| US20090143288A1 (en) | 2007-03-13 | 2009-06-04 | Roche Palo Alto Llc | Peptide-complement conjugates |
| US20140271680A1 (en) | 2011-08-12 | 2014-09-18 | Universite Paris-Est Creteil Val De Marne | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
| US11629196B2 (en) | 2020-04-27 | 2023-04-18 | Incelldx, Inc. | Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997045543A2 (en) * | 1996-05-28 | 1997-12-04 | The Government Of The United States Of America, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health | Cc chemokine receptor 5, antibodies thereto, transgenic animals |
| WO1997047319A1 (en) * | 1996-06-14 | 1997-12-18 | Progenics Pharmaceuticals, Inc. | Uses of a chemokine receptor for inhibiting hiv-1 infection |
| US6528625B1 (en) * | 1996-10-28 | 2003-03-04 | Millennium Pharmaceuticals, Inc. | Anti-CCR5 antibodies and kits comprising same |
-
1999
- 1999-12-16 EP EP08173136A patent/EP2088158A3/en not_active Withdrawn
- 1999-12-16 HK HK02102467.8A patent/HK1041207B/en not_active IP Right Cessation
- 1999-12-16 DK DK99966466T patent/DK1144006T3/da active
- 1999-12-16 WO PCT/US1999/030345 patent/WO2000035409A2/en not_active Ceased
- 1999-12-16 ES ES99966466T patent/ES2296416T3/es not_active Expired - Lifetime
- 1999-12-16 EP EP99966466A patent/EP1144006B1/en not_active Expired - Lifetime
- 1999-12-16 JP JP2000587730A patent/JP2002538771A/ja not_active Ceased
- 1999-12-16 PT PT99966466T patent/PT1144006E/pt unknown
- 1999-12-16 DE DE69937369T patent/DE69937369T2/de not_active Expired - Lifetime
- 1999-12-16 MX MXPA01006097A patent/MXPA01006097A/es not_active IP Right Cessation
- 1999-12-16 AU AU21996/00A patent/AU773175B2/en not_active Ceased
- 1999-12-16 AT AT99966466T patent/ATE375802T1/de not_active IP Right Cessation
- 1999-12-16 CA CA002355607A patent/CA2355607A1/en not_active Abandoned
-
2004
- 2004-08-20 AU AU2004205164A patent/AU2004205164A1/en not_active Abandoned
- 2004-08-20 AU AU2004205165A patent/AU2004205165A1/en not_active Abandoned
-
2008
- 2008-01-17 CY CY20081100062T patent/CY1107858T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1144006A4 (en) | 2004-11-24 |
| EP1144006A2 (en) | 2001-10-17 |
| WO2000035409A3 (en) | 2000-09-14 |
| EP2088158A2 (en) | 2009-08-12 |
| AU773175B2 (en) | 2004-05-20 |
| CA2355607A1 (en) | 2000-06-22 |
| EP2088158A3 (en) | 2010-01-20 |
| CY1107858T1 (el) | 2013-06-19 |
| EP1144006B1 (en) | 2007-10-17 |
| WO2000035409A2 (en) | 2000-06-22 |
| AU2004205165A1 (en) | 2004-09-16 |
| AU2199600A (en) | 2000-07-03 |
| HK1041207A1 (en) | 2002-07-05 |
| MXPA01006097A (es) | 2002-04-15 |
| JP2002538771A (ja) | 2002-11-19 |
| DE69937369T2 (de) | 2008-07-24 |
| AU2004205164A1 (en) | 2004-09-16 |
| ES2296416T3 (es) | 2008-04-16 |
| DE69937369D1 (de) | 2007-11-29 |
| ATE375802T1 (de) | 2007-11-15 |
| PT1144006E (pt) | 2007-12-11 |
| HK1041207B (en) | 2007-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1107858T1 (el) | Ccr5 αντισωματα pa14 | |
| DE69429095D1 (de) | Humanisierte antikoerper | |
| KR960704938A (ko) | Fas 길항제 및 그의 용도(Fas Antagonists and Uses Thereof) | |
| NO942912L (no) | Konstruksjon, kloning og ekspresjon av humaniserte, monoklonale antistoffer mot humant interleukin-5 | |
| UA89017C2 (uk) | ЛЮДСЬКЕ АНТИТІЛО, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ЛЮДСЬКИМ TNFSF13b | |
| ATE324381T1 (de) | Mutiertes scfv-fragment des okt-3 antikörpers | |
| KR960704576A (ko) | CD40에 대한 항체(Antibodies to CD40) | |
| PE20001316A1 (es) | Anticuerpo humanizado especifico para 4-1bb humano y composicion farmaceutica que lo contiene | |
| ES2187954T3 (es) | Anticuerpos anti-integrina avb3 antagonistas. | |
| WO2003078468A3 (de) | Verwendung einer an cd28 bindenden wirksubstanz zur herstellung einer pharmazeutischen zusammensetzung | |
| EP2186884A3 (en) | HCV-anti-core monoclonal antibody | |
| DK1860188T3 (da) | Human cytokin-receptor | |
| CA2221893A1 (fr) | Anticorps specifique de staphylococcus aureus et utilisations | |
| WO2003048194A3 (de) | Peptid oder protein enthaltend ein c'-d loop der cd28 rezeptorfamilie | |
| AU2707992A (en) | Monoclonal antibodies to hepatitis c virus | |
| MX9702422A (es) | Anticuerpos recombinantes contra fas y adn para los mismos. | |
| EP0155172A3 (en) | Anti-human lung cancer monoclonal antibodies | |
| BR9702101A (pt) | Hibridoma e anticorpo monoclonal | |
| BR0007827A (pt) | Anticorpos e fragmento fv que reconhecemantìgeno ior c2 | |
| CA2137551A1 (en) | A novel endothelial cell molecule mediating lymphocyte binding in man | |
| DK1161522T3 (da) | Fremgangsmåde til isolering af CD8+-celler og beslægtede hybridomaceller, antistoffer og polypeptider | |
| EP0349258A3 (en) | Method of determining the differentiation of a human t-cell | |
| DK557187D0 (da) | Murin hybridoma lym-1, dermed fremstillet monoklonalt antistof og fremgangsmaade til fremstilling af antistoffet | |
| DK557287D0 (da) | Murin hybridoma lym-2, dermed fremstillet monoklonalt antistof og fremangsmaade til fremstilling af antistoffet |