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DK1034000T3 - Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion - Google Patents

Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion

Info

Publication number
DK1034000T3
DK1034000T3 DK98955673T DK98955673T DK1034000T3 DK 1034000 T3 DK1034000 T3 DK 1034000T3 DK 98955673 T DK98955673 T DK 98955673T DK 98955673 T DK98955673 T DK 98955673T DK 1034000 T3 DK1034000 T3 DK 1034000T3
Authority
DK
Denmark
Prior art keywords
prevent
effects related
pathogenic effects
retrovirus infection
preparing vaccines
Prior art date
Application number
DK98955673T
Other languages
English (en)
Inventor
Pierre-Francois Serres
Christophe Geourjon
Gilbert Deleage
Christophe Combet
Original Assignee
Mymetics Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mymetics Sa filed Critical Mymetics Sa
Application granted granted Critical
Publication of DK1034000T3 publication Critical patent/DK1034000T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK98955673T 1997-11-17 1998-11-17 Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion DK1034000T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9714387A FR2771011B1 (fr) 1997-11-17 1997-11-17 Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale
PCT/FR1998/002447 WO1999025377A1 (fr) 1997-11-17 1998-11-17 Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale

Publications (1)

Publication Number Publication Date
DK1034000T3 true DK1034000T3 (da) 2007-06-04

Family

ID=9513450

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98955673T DK1034000T3 (da) 1997-11-17 1998-11-17 Fremgangsmåde til fremstilling af vacciner til forebyggelse af de patogene virkninger relateret til en HIV-retrovirusinfektion

Country Status (19)

Country Link
US (3) US6455265B1 (da)
EP (1) EP1034000B1 (da)
JP (1) JP4837823B2 (da)
KR (1) KR20010032210A (da)
CN (1) CN1281371A (da)
AP (1) AP2000001841A0 (da)
AT (1) ATE353017T1 (da)
AU (1) AU1243499A (da)
BR (1) BR9814204A (da)
CA (1) CA2309676C (da)
DE (1) DE69837012T2 (da)
DK (1) DK1034000T3 (da)
EA (1) EA200000528A1 (da)
ES (1) ES2281938T3 (da)
FR (1) FR2771011B1 (da)
IL (2) IL136163A0 (da)
OA (1) OA11522A (da)
PT (1) PT1034000E (da)
WO (1) WO1999025377A1 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2771011B1 (fr) * 1997-11-17 2000-01-28 Hippocampe Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale
CN1396178A (zh) * 2002-06-17 2003-02-12 成都阳辉生物科技有限责任公司 抗乙肝病毒等包膜病毒感染的工程多肽及其制备方法
ES2366185T3 (es) * 2003-04-11 2011-10-18 Institut Pasteur Vacunas de péptidos sintéticas para vih: el epítopo de cbd como un inmunógeno eficaz para provocar anticuerpos ampliamente neutralizantes contra el vih.
RU2390525C2 (ru) * 2003-07-30 2010-05-27 Майметикс Корпорейшн Новая растворимая и стабилизированная тримерная форма полипептидов gp41
AU2005267607B8 (en) * 2003-09-11 2009-07-16 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
US7201903B2 (en) * 2003-09-11 2007-04-10 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
ATE434763T1 (de) * 2003-12-18 2009-07-15 Idexx Lab Inc Verfahren zum nachweis des felinen immunschwächevirus
DE602005027326D1 (de) * 2004-02-19 2011-05-19 Idexx Lab Inc Verfahren und vorrichtung zum nachweis von katzen-immunschwächevirus
WO2005095442A1 (en) * 2004-03-30 2005-10-13 Institut Gustave Roussy Polypeptide sequence involved in the modulation of the immunosuppresive effect of viral proteins
EP1761556A1 (en) * 2004-06-30 2007-03-14 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus (fiv) comprising the use of peptides derived from the v3 region of the fiv env protein
CA2570610A1 (en) * 2004-06-30 2006-02-02 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
US7291338B2 (en) * 2005-03-09 2007-11-06 Idexx Laboratories, Inc. Method and device for detecting feline immunodeficiency virus
US20090232826A1 (en) * 2005-05-02 2009-09-17 Mymetics Corporation Antibody or a fragment thereof, having neutralizing activity against hiv but not against il2
TWI343180B (en) * 2005-07-01 2011-06-01 Ind Tech Res Inst The acoustic wave sensing-device integrated with micro channels
WO2007099387A1 (en) * 2006-03-03 2007-09-07 Mymetics Corporation Virosome-like vesicles comprising gp41-derived antigens
CN1869704B (zh) * 2006-06-14 2010-06-30 厦门大学 快速鉴定与病原菌互作的宿主蛋白的方法
US20110195089A1 (en) * 2008-10-08 2011-08-11 The Adminstrators Of The Tulane Educational Fund Compositions, methods, and kits for enhancing the immunogenicity of pathogenic antigens
EA021191B1 (ru) 2009-02-06 2015-04-30 Майметикс Корпорейшн НОВЫЕ АНТИГЕНЫ gp41
BRPI1008721A2 (pt) 2009-02-06 2016-03-08 Inserm Inst Nat De La Santé Et De La Rech Médicale métodos para tratamento terapêutico ou profiláctico de hiv, método profilático, composição terapêutica ou preparação, associação de vacina terapêutica, kit para implantação de método terapêutico
WO2011022725A2 (en) * 2009-08-21 2011-02-24 Dana-Farber Cancer Institute, Inc. Mimotopes of hiv and uses thereof
US8809004B2 (en) 2010-04-02 2014-08-19 Idexx Laboratories, Inc. Detection of feline immunodeficiency virus
PT2691530T (pt) 2011-06-10 2018-05-10 Univ Oregon Health & Science Glicoproteínas e vectores recombinantes cmv
JP6438396B2 (ja) 2012-08-30 2018-12-12 メリアル インコーポレイテッド 不活化ワクチンを作製するための、ならびに組換えタンパク質をリフォールディング／可溶化させるための高圧デバイスおよび方法
US20220065857A1 (en) * 2018-12-12 2022-03-03 The Johns Hopkins University Hiv serosignatures for cross-sectional incidence estimation
WO2021185851A1 (en) 2020-03-17 2021-09-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Vaccine compositions for hiv prevention and treatment
CN111701016A (zh) * 2020-06-28 2020-09-25 张全志 逆转录病毒原病毒序列在逆转录病毒疫苗设计中的应用
CN118515733B (zh) * 2023-02-20 2025-11-18 菲鹏生物股份有限公司 Hiv蛋白及其在检测hiv抗体中的应用
CN118561966B (zh) * 2024-05-20 2025-07-11 浙江大学 人内源性逆转录病毒包膜蛋白突变体、截短体及其用途

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Publication number Priority date Publication date Assignee Title
WO1993001304A1 (en) * 1991-07-10 1993-01-21 Synbiotics Corporation Synthetic peptides related to fiv-env proteins
WO1994002505A1 (en) * 1992-07-20 1994-02-03 Duke University Compounds which inhibit hiv replication
GB9219936D0 (en) * 1992-09-21 1992-11-04 Pitman Moore Inc Vaccines
US6479055B1 (en) * 1993-06-07 2002-11-12 Trimeris, Inc. Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission
US6017536A (en) * 1993-06-07 2000-01-25 Trimeris, Inc. Simian immunodeficiency virus peptides with antifusogenic and antiviral activities
FR2771011B1 (fr) * 1997-11-17 2000-01-28 Hippocampe Obtention de vaccins destines a prevenir les effets pathogenes associes a une infection retrovirale

Also Published As

Publication number Publication date
WO1999025377A1 (fr) 1999-05-27
US20040014046A1 (en) 2004-01-22
CA2309676C (fr) 2012-08-07
ATE353017T1 (de) 2007-02-15
CA2309676A1 (fr) 1999-05-27
FR2771011B1 (fr) 2000-01-28
JP2001524456A (ja) 2001-12-04
EP1034000A1 (fr) 2000-09-13
AP2000001841A0 (en) 2000-06-30
US7253270B2 (en) 2007-08-07
CN1281371A (zh) 2001-01-24
IL136163A0 (en) 2001-05-20
US20050048478A9 (en) 2005-03-03
DE69837012T2 (de) 2007-11-29
BR9814204A (pt) 2000-10-03
KR20010032210A (ko) 2001-04-16
IL136163A (en) 2007-07-04
US6455265B1 (en) 2002-09-24
AU1243499A (en) 1999-06-07
EP1034000B1 (fr) 2007-01-31
US7829683B2 (en) 2010-11-09
OA11522A (fr) 2004-02-09
FR2771011A1 (fr) 1999-05-21
JP4837823B2 (ja) 2011-12-14
US20080003229A1 (en) 2008-01-03
EA200000528A1 (ru) 2001-02-26
DE69837012D1 (de) 2007-03-22
PT1034000E (pt) 2007-05-31
ES2281938T3 (es) 2007-10-01

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