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DK1023328T3 - 6-Substituted carboxylated polysaccharides - Google Patents

6-Substituted carboxylated polysaccharides

Info

Publication number
DK1023328T3
DK1023328T3 DK98954354T DK98954354T DK1023328T3 DK 1023328 T3 DK1023328 T3 DK 1023328T3 DK 98954354 T DK98954354 T DK 98954354T DK 98954354 T DK98954354 T DK 98954354T DK 1023328 T3 DK1023328 T3 DK 1023328T3
Authority
DK
Denmark
Prior art keywords
carboxylated polysaccharides
polysaccharides
procedure
substituted carboxylated
carbon
Prior art date
Application number
DK98954354T
Other languages
Danish (da)
Inventor
Riaz Ahmed Khan
Regina Vesnaver
Luca Stucchi
Marco Bosco
Original Assignee
Eurand Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Pharmaceuticals Ltd filed Critical Eurand Pharmaceuticals Ltd
Application granted granted Critical
Publication of DK1023328T3 publication Critical patent/DK1023328T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A new class of polysaccharides containing carboxylic groups selectively substituted with halogens on the carbon atom on position 6 of the glicopyranosidic residue and the procedure to obtain these derivatives is therein described. The procedure entails the halogenation of carboxylated polysaccharides with alkyl aryl sulfonyl-halides in organic solvent. The products of this invention can be used as substrates in synthesis where the reactive site is the carbon that binds the halogen. Moreover, they can be used in the medical-diagnostic field.
DK98954354T 1997-10-08 1998-10-06 6-Substituted carboxylated polysaccharides DK1023328T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI002285A IT1295298B1 (en) 1997-10-08 1997-10-08 6-REPLACED CARBOXYLATE POLYSACCHARIDES
PCT/EP1998/006346 WO1999018133A1 (en) 1997-10-08 1998-10-06 Carboxylated polysaccharides 6-substituted

Publications (1)

Publication Number Publication Date
DK1023328T3 true DK1023328T3 (en) 2002-07-08

Family

ID=11378011

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98954354T DK1023328T3 (en) 1997-10-08 1998-10-06 6-Substituted carboxylated polysaccharides

Country Status (10)

Country Link
US (1) US6482941B1 (en)
EP (1) EP1023328B1 (en)
AT (1) ATE215098T1 (en)
AU (1) AU1150699A (en)
DE (1) DE69804482T2 (en)
DK (1) DK1023328T3 (en)
ES (1) ES2174506T3 (en)
IT (1) IT1295298B1 (en)
PT (1) PT1023328E (en)
WO (1) WO1999018133A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318403B1 (en) 2000-03-17 2003-08-25 Cooperativa Ct Ricerche Poly T POLYSACCHARID ESTERS OF N-DERIVATIVES OF GLUTAMIC ACID.
ITTS20010013A1 (en) * 2001-06-04 2002-12-04 Ct Ricerche Poly Tec H A R L S NEW HALURONAN DERIVATIVES.
ITTS20010016A1 (en) * 2001-06-20 2002-12-20 Ct Ricerche Poly Tec H A R L S REGULAR CROSS-LINKED POLYSACCHARIDES.
ITTS20010017A1 (en) * 2001-07-17 2003-01-17 Ct Ricerche Polytech Soc Coop POLYESACCHARIDIC ESTERS OF RETINOIC ACID.
JP2005531647A (en) * 2002-04-11 2005-10-20 カルボマー インク New imaging probe
FR2839885B1 (en) * 2002-05-27 2006-02-10 Oreal LONG-COSMETIC COSMETIC COMPOSITION CONTAINING POLYSACCHARIDE WITH FLUORINATED GROUPS DISSOLVED OR DISPERSE IN THE MEDIUM
AU2003285133A1 (en) * 2003-11-05 2005-06-24 The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services Biofunctionalized quantum dots for biological imaging
IE20060049A1 (en) * 2006-01-25 2007-08-08 Eurand Pharmaceuticals Ltd A novel drug delivery system: use of hyaluronic acid as a carrier moleclue for different classes of therapeutic active agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60202101A (en) 1984-03-27 1985-10-12 Shizuokaken Production of sulfonate ester of pectic substance

Also Published As

Publication number Publication date
WO1999018133A1 (en) 1999-04-15
PT1023328E (en) 2002-09-30
EP1023328B1 (en) 2002-03-27
DE69804482D1 (en) 2002-05-02
ITMI972285A1 (en) 1999-04-08
ATE215098T1 (en) 2002-04-15
EP1023328A1 (en) 2000-08-02
IT1295298B1 (en) 1999-05-04
US6482941B1 (en) 2002-11-19
ES2174506T3 (en) 2002-11-01
DE69804482T2 (en) 2002-11-21
AU1150699A (en) 1999-04-27

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