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DK1093451T3 - Solid compositions suitable for oral administration containing non-hygroscopic salts of L-carnitine and alkanoyl-L-carnitines - Google Patents

Solid compositions suitable for oral administration containing non-hygroscopic salts of L-carnitine and alkanoyl-L-carnitines

Info

Publication number
DK1093451T3
DK1093451T3 DK99929707T DK99929707T DK1093451T3 DK 1093451 T3 DK1093451 T3 DK 1093451T3 DK 99929707 T DK99929707 T DK 99929707T DK 99929707 T DK99929707 T DK 99929707T DK 1093451 T3 DK1093451 T3 DK 1093451T3
Authority
DK
Denmark
Prior art keywords
solid compositions
carnitines
carnitine
oral administration
alkanoyl
Prior art date
Application number
DK99929707T
Other languages
Danish (da)
Inventor
Mose Santaniello
Nazareno Scafetta
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK1093451T3 publication Critical patent/DK1093451T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic
    • C07C65/11—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic with carboxyl groups on a condensed ring system containing two rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Non-hygrocopic salts of L-carnitine and of the lower alkanoyl L-carnitines with pamoic acid are described, which are used to prepare solid compositions suitable for oral administration. Solid compositions containing such salts are also described.
DK99929707T 1998-07-03 1999-07-02 Solid compositions suitable for oral administration containing non-hygroscopic salts of L-carnitine and alkanoyl-L-carnitines DK1093451T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT98RM000445A IT1299544B1 (en) 1998-07-03 1998-07-03 SOLID COMPOSITIONS SUITABLE FOR ORAL ADMINISTRATION INCLUDING NON-HYGROSCOPIC SALTS OF L-CARNITINE AND L-CARNITINE ALCANOYLS
PCT/IT1999/000202 WO2000001662A1 (en) 1998-07-03 1999-07-02 Solid compositions suitable for oral administration containing non-hygroscopic salts of l-carnitine and alkanoyl l-carnitines

Publications (1)

Publication Number Publication Date
DK1093451T3 true DK1093451T3 (en) 2004-01-05

Family

ID=11406029

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99929707T DK1093451T3 (en) 1998-07-03 1999-07-02 Solid compositions suitable for oral administration containing non-hygroscopic salts of L-carnitine and alkanoyl-L-carnitines

Country Status (14)

Country Link
US (1) US6465515B2 (en)
EP (1) EP1093451B1 (en)
JP (1) JP2002519403A (en)
KR (1) KR100642729B1 (en)
AT (1) ATE248805T1 (en)
AU (1) AU4647999A (en)
CA (1) CA2335503A1 (en)
DE (1) DE69911021T2 (en)
DK (1) DK1093451T3 (en)
ES (1) ES2205843T3 (en)
IL (1) IL140487A (en)
IT (1) IT1299544B1 (en)
PT (1) PT1093451E (en)
WO (1) WO2000001662A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1317048B1 (en) * 2000-06-23 2003-05-26 Sigma Tau Ind Farmaceuti USE OF PAMOIC ACID OR ITS DERIVATIVE, OR ANALOGUE, FOR THE PREPARATION OF A MEDICATION FOR THE TREATMENT OF DISEASES
JP2006111550A (en) * 2004-10-13 2006-04-27 Nisshin Pharma Inc Carnitine-containing products
EP4362697A1 (en) * 2021-06-07 2024-05-08 Kaesler Nutrition GmbH Carnitine formulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51711B1 (en) * 1977-11-03 1987-03-04 Sigma Tau Ind Farmaceuti Carnitine derivatives
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
IT1209564B (en) * 1984-06-29 1989-08-30 Magis Farmaceutici DERIVATIVES OF L-CARNITINE OR L-ACYL CARNITINE.
IT1188176B (en) * 1985-07-05 1988-01-07 Bicresearch Spa SALT OF CARNITINE PARTICULARLY SUITABLE FOR ORAL USE
DE3841664A1 (en) * 1988-12-10 1990-10-11 Fresenius Ag Non-hygroscopic salt of L-carnitine
US5073376A (en) * 1989-12-22 1991-12-17 Lonza Ltd. Preparations containing l-carnitine

Also Published As

Publication number Publication date
IL140487A0 (en) 2002-02-10
ITRM980445A0 (en) 1998-07-03
US6465515B2 (en) 2002-10-15
EP1093451A1 (en) 2001-04-25
CA2335503A1 (en) 2000-01-13
KR100642729B1 (en) 2006-11-03
US20010009923A1 (en) 2001-07-26
ES2205843T3 (en) 2004-05-01
IT1299544B1 (en) 2000-03-16
EP1093451B1 (en) 2003-09-03
DE69911021D1 (en) 2003-10-09
ITRM980445A1 (en) 2000-01-03
KR20010071720A (en) 2001-07-31
WO2000001662A1 (en) 2000-01-13
AU4647999A (en) 2000-01-24
ATE248805T1 (en) 2003-09-15
JP2002519403A (en) 2002-07-02
HK1035710A1 (en) 2001-12-07
PT1093451E (en) 2003-12-31
IL140487A (en) 2004-07-25
DE69911021T2 (en) 2004-04-01

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