DK1082116T3 - Anvendelse af 4-piperidinmethanolderivater til behandling af neurologiske sygdomme - Google Patents
Anvendelse af 4-piperidinmethanolderivater til behandling af neurologiske sygdommeInfo
- Publication number
- DK1082116T3 DK1082116T3 DK99948543T DK99948543T DK1082116T3 DK 1082116 T3 DK1082116 T3 DK 1082116T3 DK 99948543 T DK99948543 T DK 99948543T DK 99948543 T DK99948543 T DK 99948543T DK 1082116 T3 DK1082116 T3 DK 1082116T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- neurological disorders
- methanol derivatives
- piperidine methanol
- compound
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 title 1
- 208000025966 Neurological disease Diseases 0.000 title 1
- XBXHCBLBYQEYTI-UHFFFAOYSA-N piperidin-4-ylmethanol Chemical class OCC1CCNCC1 XBXHCBLBYQEYTI-UHFFFAOYSA-N 0.000 title 1
- 208000029726 Neurodevelopmental disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9801516A SE9801516D0 (sv) | 1998-04-30 | 1998-04-30 | M100907/4-Piperidinemethanol derivatives for autism |
| PCT/SE1999/000683 WO1999056750A1 (en) | 1998-04-30 | 1999-04-26 | Use of 4-piperidinemethanol derivatives in treatment of neurodevelopmental disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1082116T3 true DK1082116T3 (da) | 2003-07-21 |
Family
ID=20411144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99948543T DK1082116T3 (da) | 1998-04-30 | 1999-04-26 | Anvendelse af 4-piperidinmethanolderivater til behandling af neurologiske sygdomme |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6358977B1 (da) |
| EP (1) | EP1082116B1 (da) |
| JP (1) | JP2002513759A (da) |
| AT (1) | ATE236634T1 (da) |
| AU (1) | AU4301699A (da) |
| CA (1) | CA2330568A1 (da) |
| DE (1) | DE69906728T2 (da) |
| DK (1) | DK1082116T3 (da) |
| ES (1) | ES2197675T3 (da) |
| NZ (1) | NZ508422A (da) |
| PT (1) | PT1082116E (da) |
| SE (1) | SE9801516D0 (da) |
| WO (1) | WO1999056750A1 (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6903187B1 (en) * | 2000-07-21 | 2005-06-07 | Allergan, Inc. | Leucine-based motif and clostridial neurotoxins |
| DE10212564B4 (de) | 2002-03-12 | 2007-04-19 | Neurobiotec Gmbh | 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne |
| PT1534391E (pt) * | 2002-07-19 | 2007-05-31 | Biovitrum Ab | Novos derivados e piperazinilo-pirazinona para o tratamento de desordens relacionadas com o receptor 5-ht |
| JP5646126B2 (ja) | 2003-12-11 | 2014-12-24 | サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． | 鎮静剤と神経伝達物質調節剤の併用、および睡眠の質の向上方法および鬱の治療方法 |
| JP4646574B2 (ja) * | 2004-08-30 | 2011-03-09 | 株式会社日立製作所 | データ処理システム |
| US20090048243A1 (en) * | 2005-01-18 | 2009-02-19 | Mitsubishi Pharma Corporation | Therapeutic agent for attention-deficit hyperactivity disorder |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3992546A (en) * | 1973-10-18 | 1976-11-16 | Ciba-Geigy Corporation | 4-Piperidinobutyrophenones as neuroleptics |
| ZA864772B (en) | 1985-07-02 | 1987-02-25 | Merrell Dow Pharma | Novel chemical compounds |
| EP0531410B1 (en) * | 1990-06-01 | 1994-11-30 | Merrell Dow Pharmaceuticals Inc. | (+)-alpha-(2,3-dimethoxyphenyl)-1-[2-(fluorophenyl)ethyl]-4-piperidinemethanol |
| US5618824A (en) | 1994-03-09 | 1997-04-08 | Merrell Pharmaceuticals Inc. | Treatment of obsessive-compulsive disorders with 5-HT2 antagonists |
-
1998
- 1998-04-30 SE SE9801516A patent/SE9801516D0/xx unknown
-
1999
- 1999-04-26 EP EP99948543A patent/EP1082116B1/en not_active Expired - Lifetime
- 1999-04-26 AU AU43016/99A patent/AU4301699A/en not_active Abandoned
- 1999-04-26 JP JP2000546775A patent/JP2002513759A/ja not_active Withdrawn
- 1999-04-26 PT PT99948543T patent/PT1082116E/pt unknown
- 1999-04-26 NZ NZ508422A patent/NZ508422A/en unknown
- 1999-04-26 AT AT99948543T patent/ATE236634T1/de not_active IP Right Cessation
- 1999-04-26 WO PCT/SE1999/000683 patent/WO1999056750A1/en not_active Ceased
- 1999-04-26 CA CA002330568A patent/CA2330568A1/en not_active Abandoned
- 1999-04-26 DE DE69906728T patent/DE69906728T2/de not_active Expired - Fee Related
- 1999-04-26 US US09/674,095 patent/US6358977B1/en not_active Expired - Fee Related
- 1999-04-26 DK DK99948543T patent/DK1082116T3/da active
- 1999-04-26 ES ES99948543T patent/ES2197675T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69906728T2 (de) | 2004-02-26 |
| PT1082116E (pt) | 2003-08-29 |
| WO1999056750A1 (en) | 1999-11-11 |
| CA2330568A1 (en) | 1999-11-11 |
| SE9801516D0 (sv) | 1998-04-30 |
| DE69906728D1 (de) | 2003-05-15 |
| JP2002513759A (ja) | 2002-05-14 |
| EP1082116B1 (en) | 2003-04-09 |
| AU4301699A (en) | 1999-11-23 |
| NZ508422A (en) | 2002-05-31 |
| US6358977B1 (en) | 2002-03-19 |
| ES2197675T3 (es) | 2004-01-01 |
| EP1082116A1 (en) | 2001-03-14 |
| ATE236634T1 (de) | 2003-04-15 |
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