DK1078006T3 - Diagnose og behandling af leverlidelser - Google Patents
Diagnose og behandling af leverlidelserInfo
- Publication number
- DK1078006T3 DK1078006T3 DK99922996T DK99922996T DK1078006T3 DK 1078006 T3 DK1078006 T3 DK 1078006T3 DK 99922996 T DK99922996 T DK 99922996T DK 99922996 T DK99922996 T DK 99922996T DK 1078006 T3 DK1078006 T3 DK 1078006T3
- Authority
- DK
- Denmark
- Prior art keywords
- disorders
- madcam
- disorder
- compositions
- useful
- Prior art date
Links
- 208000019423 liver disease Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 6
- 208000035475 disorder Diseases 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 3
- 230000003993 interaction Effects 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 102000016289 Cell Adhesion Molecules Human genes 0.000 abstract 1
- 108010067225 Cell Adhesion Molecules Proteins 0.000 abstract 1
- 208000028782 Hereditary disease Diseases 0.000 abstract 1
- 208000019468 Iatrogenic Disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001587 cholestatic effect Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000028709 inflammatory response Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 201000000306 sarcoidosis Diseases 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70546—Integrin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Transplantation (AREA)
- Biotechnology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7840598A | 1998-05-13 | 1998-05-13 | |
| PCT/US1999/010520 WO1999058573A1 (en) | 1998-05-13 | 1999-05-12 | Diagnosis and treatment of hepatic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1078006T3 true DK1078006T3 (da) | 2009-06-02 |
Family
ID=22143829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99922996T DK1078006T3 (da) | 1998-05-13 | 1999-05-12 | Diagnose og behandling af leverlidelser |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1078006B1 (da) |
| JP (2) | JP4817494B2 (da) |
| AT (1) | ATE424417T1 (da) |
| AU (1) | AU3986699A (da) |
| CA (1) | CA2330000C (da) |
| DE (1) | DE69940503D1 (da) |
| DK (1) | DK1078006T3 (da) |
| ES (1) | ES2321994T3 (da) |
| IL (2) | IL139129A0 (da) |
| WO (1) | WO1999058573A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2257388T3 (es) * | 2001-11-05 | 2006-08-01 | Warner-Lambert Company Llc | Procedimientos y composiciones para la seleccion de integrinas. |
| WO2004081049A1 (en) * | 2003-03-10 | 2004-09-23 | Auckland Uniservices Limited | Monoclonal antibodies that recognise mucosal addressin cell adhesion molecule-1 (madcam-1), soluble madcam-1 and uses thereof |
| CN1956738B (zh) * | 2004-01-09 | 2013-05-29 | 辉瑞大药厂 | MAdCAM抗体 |
| ATE483732T1 (de) * | 2005-07-08 | 2010-10-15 | Pfizer Ltd | Madcam-antikörper |
| JP5847188B2 (ja) * | 2010-10-25 | 2016-01-20 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | ｓＶＣＡＭおよび／またはｓＭＡｄＣＡＭレベルの差を関連付けることにより、アルファ−４インテグリン活性の差を決定するための方法 |
| MA41636A (fr) * | 2015-03-06 | 2018-01-09 | Millennium Pharm Inc | Méthode de traitement de la cholangite sclérosante primitive |
| JP6970975B2 (ja) * | 2016-07-20 | 2021-11-24 | 国立大学法人京都大学 | ＩｇＧ４関連疾患の検査方法 |
| SG11202000298VA (en) | 2017-07-14 | 2020-02-27 | Pfizer | Antibodies to madcam |
| US20200392231A1 (en) * | 2017-12-06 | 2020-12-17 | Emory University | Methods of Managing Hepatic Steatosis |
| AU2024282654A1 (en) | 2023-05-30 | 2025-12-04 | Paragon Therapeutics, Inc. | Alpha4beta7 integrin antibody compositions and methods of use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT808367E (pt) * | 1995-02-10 | 2007-10-22 | Millennium Pharm Inc | Adressinas vasculares da mucosa e suas utilizações |
| US6037324A (en) * | 1996-01-04 | 2000-03-14 | Leukosite, Inc. | Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor |
-
1999
- 1999-05-12 JP JP2000548375A patent/JP4817494B2/ja not_active Expired - Lifetime
- 1999-05-12 IL IL13912999A patent/IL139129A0/xx active IP Right Grant
- 1999-05-12 ES ES99922996T patent/ES2321994T3/es not_active Expired - Lifetime
- 1999-05-12 DK DK99922996T patent/DK1078006T3/da active
- 1999-05-12 DE DE69940503T patent/DE69940503D1/de not_active Expired - Lifetime
- 1999-05-12 CA CA2330000A patent/CA2330000C/en not_active Expired - Lifetime
- 1999-05-12 EP EP99922996A patent/EP1078006B1/en not_active Expired - Lifetime
- 1999-05-12 AU AU39866/99A patent/AU3986699A/en not_active Abandoned
- 1999-05-12 AT AT99922996T patent/ATE424417T1/de not_active IP Right Cessation
- 1999-05-12 WO PCT/US1999/010520 patent/WO1999058573A1/en not_active Ceased
-
2000
- 2000-10-18 IL IL139129A patent/IL139129A/en not_active IP Right Cessation
-
2010
- 2010-06-04 JP JP2010129284A patent/JP2010280659A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1078006A1 (en) | 2001-02-28 |
| CA2330000A1 (en) | 1999-11-18 |
| AU3986699A (en) | 1999-11-29 |
| JP4817494B2 (ja) | 2011-11-16 |
| IL139129A (en) | 2006-09-05 |
| JP2002514660A (ja) | 2002-05-21 |
| IL139129A0 (en) | 2001-11-25 |
| WO1999058573A1 (en) | 1999-11-18 |
| ES2321994T3 (es) | 2009-06-15 |
| JP2010280659A (ja) | 2010-12-16 |
| ATE424417T1 (de) | 2009-03-15 |
| EP1078006B1 (en) | 2009-03-04 |
| DE69940503D1 (de) | 2009-04-16 |
| CA2330000C (en) | 2015-06-23 |
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