DK1066044T3 - Dextranformuleringer til behandling af inflammatoriske ledsygdomme - Google Patents
Dextranformuleringer til behandling af inflammatoriske ledsygdommeInfo
- Publication number
- DK1066044T3 DK1066044T3 DK99909118T DK99909118T DK1066044T3 DK 1066044 T3 DK1066044 T3 DK 1066044T3 DK 99909118 T DK99909118 T DK 99909118T DK 99909118 T DK99909118 T DK 99909118T DK 1066044 T3 DK1066044 T3 DK 1066044T3
- Authority
- DK
- Denmark
- Prior art keywords
- dextran
- treatment
- molecular weight
- joint diseases
- inflammatory joint
- Prior art date
Links
- 229920002307 Dextran Polymers 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000012659 Joint disease Diseases 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 206010003246 arthritis Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000006820 Arthralgia Diseases 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 230000002902 bimodal effect Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 208000018937 joint inflammation Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000008733 trauma Effects 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/049,055 US5902800A (en) | 1998-03-27 | 1998-03-27 | Dextran formulations and method for treatment of inflammatory joint disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1066044T3 true DK1066044T3 (da) | 2004-07-12 |
Family
ID=21957832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99909118T DK1066044T3 (da) | 1998-03-27 | 1999-03-25 | Dextranformuleringer til behandling af inflammatoriske ledsygdomme |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5902800A (da) |
| EP (1) | EP1066044B1 (da) |
| JP (1) | JP4511031B2 (da) |
| AT (1) | ATE261308T1 (da) |
| AU (1) | AU753124B2 (da) |
| BR (1) | BR9909199A (da) |
| CA (1) | CA2326510C (da) |
| DE (1) | DE69915458T2 (da) |
| DK (1) | DK1066044T3 (da) |
| ES (1) | ES2217741T3 (da) |
| MX (1) | MXPA00009159A (da) |
| WO (1) | WO1999049874A1 (da) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19908441C1 (de) * | 1999-02-26 | 2000-08-31 | Chakravarty Adusumalli | Injektionslösung zur Behandlung von Arthrosen |
| US6800298B1 (en) * | 2000-05-11 | 2004-10-05 | Clemson University | Biological lubricant composition and method of applying lubricant composition |
| US7387796B2 (en) * | 2002-01-30 | 2008-06-17 | Hebert Rolland F | Stable compositions of S-adenosyl-l-methionine with dextran |
| EP2662211A1 (en) | 2002-06-24 | 2013-11-13 | Tufts University | Silk biomaterials and methods of use thereof |
| CA2562415C (en) | 2003-04-10 | 2015-10-27 | Tufts University | Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof |
| JP2008502739A (ja) | 2004-06-11 | 2008-01-31 | トラスティーズ オブ タフツ カレッジ | 絹に基づく薬物送達システム |
| US20100028451A1 (en) | 2006-09-26 | 2010-02-04 | Trustees Of Tufts College | Silk microspheres for encapsulation and controlled release |
| EP2129772B1 (en) | 2007-02-27 | 2016-07-27 | Trustees Of Tufts College | Tissue-engineered silk organs |
| EP2664323B1 (en) | 2007-04-16 | 2020-07-29 | Corium, Inc. | Solvent-cast microneedle arrays containing active |
| US9808557B2 (en) | 2007-08-10 | 2017-11-07 | Trustees Of Tufts College | Tubular silk compositions and methods of use thereof |
| DK2480075T3 (da) * | 2009-09-23 | 2020-09-28 | Glenpharma Ab | Sammensætninger og fremgangsmåder til at fremkalde eller forbedre reparation af bindevæv |
| JP6327852B2 (ja) | 2010-05-04 | 2018-05-23 | コリウム インターナショナル， インコーポレイテッド | 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス |
| WO2011160146A1 (en) | 2010-06-23 | 2011-12-29 | Croma-Pharma Gesellschaft M.B.H. | Pharmaceutical preparation containing dextran and sodium hyaluronate for the treatment of joint disorders |
| GB201020300D0 (en) * | 2010-11-30 | 2011-01-12 | Vitrolife Sweden Ab | Product |
| WO2012145652A1 (en) | 2011-04-20 | 2012-10-26 | Trustees Of Tufts College | Dynamic silk coatings for implantable devices |
| US9554989B2 (en) | 2012-03-20 | 2017-01-31 | Trustees Of Tufts College | Silk reservoirs for drug delivery |
| US20150056294A1 (en) | 2012-04-13 | 2015-02-26 | Trustees Of Tufts College | Methods and compositions for preparing a silk microsphere |
| WO2014012101A1 (en) | 2012-07-13 | 2014-01-16 | Trustees Of Tufts College | Silk powder compaction for production of constructs with high mechanical strength and stiffness |
| CN105073178B (zh) | 2012-12-21 | 2019-07-30 | 考里安国际公司 | 用于治疗剂递送的微阵列及其使用方法 |
| JP6487899B2 (ja) | 2013-03-12 | 2019-03-20 | コリウム インターナショナル， インコーポレイテッド | 微小突起アプリケータ |
| AU2014237357B2 (en) | 2013-03-15 | 2019-11-28 | Corium Pharma Solutions, Inc. | Multiple impact microprojection applicators and methods of use |
| US10384045B2 (en) | 2013-03-15 | 2019-08-20 | Corium, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
| BR112015022625B1 (pt) | 2013-03-15 | 2023-01-31 | Corium, Inc | Aparelho de microestrutura para entrega de agente terapêutico |
| US11376329B2 (en) | 2013-03-15 | 2022-07-05 | Trustees Of Tufts College | Low molecular weight silk compositions and stabilizing silk compositions |
| EP3412682B1 (en) | 2013-03-15 | 2022-08-31 | Trustees Of Tufts College | Low molecular weight silk compositions and stabilizing silk compositions |
| WO2014176458A2 (en) | 2013-04-24 | 2014-10-30 | Trustees Of Tufts College | Bioresorbable biopolymer anastomosis devices |
| WO2015117624A1 (en) | 2014-02-10 | 2015-08-13 | Bio-E.R.G. S.R.L. | Method for the production of dextran |
| US10624843B2 (en) | 2014-09-04 | 2020-04-21 | Corium, Inc. | Microstructure array, methods of making, and methods of use |
| US10758645B2 (en) | 2014-12-17 | 2020-09-01 | Tufts University | Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair |
| WO2017004067A1 (en) | 2015-06-29 | 2017-01-05 | Corium International, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
| CA2995233C (en) | 2015-07-20 | 2024-01-02 | Tufts University | Biodegradable silk ear tubes |
| US10864299B2 (en) | 2016-04-29 | 2020-12-15 | Trustees Of Tufts College | Artificial silk based innervated cornea |
| US11298443B2 (en) | 2016-07-01 | 2022-04-12 | Trustees Of Tufts College | Innervated artificial skin |
| WO2018026853A1 (en) | 2016-08-01 | 2018-02-08 | Trustees Of Tufts College | Biomimetic mechanical tension driven fabrication of nanofibrillar architecture |
| WO2018136754A1 (en) | 2017-01-20 | 2018-07-26 | Massachusetts Institute Of Technology | Injectable polymer micro-depots for controlled local drug delivery |
| US11419947B2 (en) | 2017-10-30 | 2022-08-23 | Massachusetts Institute Of Technology | Layer-by-layer nanoparticles for cytokine therapy in cancer treatment |
| WO2019094702A1 (en) | 2017-11-10 | 2019-05-16 | Cocoon Biotech Inc. | Ocular applications of silk-based products |
| KR102075596B1 (ko) * | 2017-12-04 | 2020-02-10 | 이일훈 | 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물 |
| WO2021002984A1 (en) | 2019-05-30 | 2021-01-07 | Massachusetts Institute Of Technology | Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids |
| WO2020247594A1 (en) | 2019-06-04 | 2020-12-10 | Cocoon Biotech Inc. | Silk-based products, formulations, and methods of use |
| KR102316719B1 (ko) * | 2020-02-04 | 2021-10-25 | 메디슨파크 주식회사 | 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물 |
| KR102172290B1 (ko) * | 2020-02-04 | 2020-10-30 | 메디슨파크 주식회사 | 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물 |
| KR102468374B1 (ko) * | 2020-10-26 | 2022-11-17 | 메디슨파크 주식회사 | 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물 |
| US12161693B2 (en) | 2021-04-14 | 2024-12-10 | Cocoon Biotech Inc. | Methods of making stable silk fibroin formulations |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4758429A (en) * | 1985-11-04 | 1988-07-19 | Gordon Robert T | Method for the treatment of arthritis and inflammatory joint diseases |
| DK505488D0 (da) * | 1987-12-21 | 1988-09-09 | Bar Shalom Daniel | Middel og anvendelse af samme |
| DK110188D0 (da) * | 1988-03-02 | 1988-03-02 | Claus Selch Larsen | High molecular weight prodrug derivatives of antiinflammatory drugs |
| JP2788340B2 (ja) * | 1989-12-21 | 1998-08-20 | 株式会社ニッショー | 炎症治療剤 |
| WO1992013541A1 (de) * | 1991-01-30 | 1992-08-20 | Hoechst Aktiengesellschaft | Die verwendung substituierter polysaccharide zur behandlung von degenerativen gelenkerkrankungen |
| AU652022B2 (en) * | 1991-02-12 | 1994-08-11 | C.R. Bard Inc. | Injectable medical device |
-
1998
- 1998-03-27 US US09/049,055 patent/US5902800A/en not_active Expired - Lifetime
-
1999
- 1999-03-25 MX MXPA00009159A patent/MXPA00009159A/es active IP Right Grant
- 1999-03-25 WO PCT/IB1999/000525 patent/WO1999049874A1/en not_active Ceased
- 1999-03-25 EP EP99909118A patent/EP1066044B1/en not_active Expired - Lifetime
- 1999-03-25 AU AU28482/99A patent/AU753124B2/en not_active Ceased
- 1999-03-25 DE DE69915458T patent/DE69915458T2/de not_active Expired - Lifetime
- 1999-03-25 CA CA002326510A patent/CA2326510C/en not_active Expired - Fee Related
- 1999-03-25 AT AT99909118T patent/ATE261308T1/de active
- 1999-03-25 BR BR9909199-2A patent/BR9909199A/pt not_active Application Discontinuation
- 1999-03-25 DK DK99909118T patent/DK1066044T3/da active
- 1999-03-25 JP JP2000540837A patent/JP4511031B2/ja not_active Expired - Fee Related
- 1999-03-25 ES ES99909118T patent/ES2217741T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1066044B1 (en) | 2004-03-10 |
| AU2848299A (en) | 1999-10-18 |
| EP1066044A1 (en) | 2001-01-10 |
| CA2326510C (en) | 2007-06-12 |
| JP4511031B2 (ja) | 2010-07-28 |
| AU753124B2 (en) | 2002-10-10 |
| MXPA00009159A (es) | 2004-11-22 |
| CA2326510A1 (en) | 1999-10-07 |
| ES2217741T3 (es) | 2004-11-01 |
| JP2002509890A (ja) | 2002-04-02 |
| BR9909199A (pt) | 2000-12-05 |
| ATE261308T1 (de) | 2004-03-15 |
| WO1999049874A1 (en) | 1999-10-07 |
| US5902800A (en) | 1999-05-11 |
| DE69915458T2 (de) | 2005-02-24 |
| DE69915458D1 (de) | 2004-04-15 |
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