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DK1051170T3 - Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration - Google Patents

Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration

Info

Publication number
DK1051170T3
DK1051170T3 DK98961174T DK98961174T DK1051170T3 DK 1051170 T3 DK1051170 T3 DK 1051170T3 DK 98961174 T DK98961174 T DK 98961174T DK 98961174 T DK98961174 T DK 98961174T DK 1051170 T3 DK1051170 T3 DK 1051170T3
Authority
DK
Denmark
Prior art keywords
nerve
chromas
prevention
accelerate
substituted aminomethyl
Prior art date
Application number
DK98961174T
Other languages
Danish (da)
English (en)
Inventor
Thomas Fahrig
Irene Gerlach
Reinhard Jork
Ervin Horvath
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK1051170T3 publication Critical patent/DK1051170T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK98961174T 1997-11-24 1998-11-11 Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration DK1051170T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19751949A DE19751949A1 (de) 1997-11-24 1997-11-24 Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
PCT/EP1998/007197 WO1999026621A1 (fr) 1997-11-24 1998-11-11 Utilisation d'aminomethyl-chromanes pour empecher la degenerescence neuronale et favoriser la regeneration neuronale

Publications (1)

Publication Number Publication Date
DK1051170T3 true DK1051170T3 (da) 2001-12-27

Family

ID=7849618

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98961174T DK1051170T3 (da) 1997-11-24 1998-11-11 Anvendelse af substituerede aminomethyl-chromaner til forebyggelse af nervedegeneration og til fremskyndelse af nerveregeneration

Country Status (30)

Country Link
US (2) US6235774B1 (fr)
EP (1) EP1051170B1 (fr)
JP (1) JP2001523716A (fr)
KR (1) KR20010032357A (fr)
CN (1) CN1134256C (fr)
AR (1) AR016973A1 (fr)
AT (1) ATE206615T1 (fr)
AU (1) AU745759B2 (fr)
BG (1) BG64167B1 (fr)
CA (1) CA2311126A1 (fr)
DE (2) DE19751949A1 (fr)
DK (1) DK1051170T3 (fr)
ES (1) ES2164465T3 (fr)
HN (1) HN1998000169A (fr)
HU (1) HUP0004369A3 (fr)
IL (1) IL135904A (fr)
IS (1) IS5496A (fr)
MY (1) MY118414A (fr)
NO (1) NO20002638L (fr)
NZ (1) NZ504656A (fr)
PE (1) PE134999A1 (fr)
PL (1) PL340674A1 (fr)
PT (1) PT1051170E (fr)
RU (1) RU2217140C2 (fr)
SI (1) SI1051170T1 (fr)
SV (1) SV1998000138A (fr)
TR (1) TR200001471T2 (fr)
TW (1) TW524690B (fr)
WO (1) WO1999026621A1 (fr)
ZA (1) ZA9810668B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
UA73981C2 (en) * 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
EP1263434A1 (fr) * 2000-03-17 2002-12-11 Alcon, Inc Composes a activite agoniste sur les recepteurs 5-ht 2? et 5-ht 1a? destines au traitement du glaucome
DE10058119A1 (de) * 2000-11-22 2002-05-23 Bayer Ag Pepinotan-Kit
SE0004455D0 (sv) * 2000-12-01 2000-12-01 Milos Pekny Method for neuron regeneration in the central nervous system
DE10101917A1 (de) * 2001-01-16 2002-07-18 Bayer Ag Verwendung von Chromanen
MXPA04000775A (es) * 2001-07-26 2004-04-20 Merck Patent Ges Mit Baschrank Uso novedoso del 2 -[5-(4-fluorofenil) -3-piridilmetilamino-metil] -cromano y sus sales fisiologicamente aceptables.
CA2458628A1 (fr) * 2001-09-12 2003-03-20 Merck Patent Gesellschaft Mit Beschraenkter Haftung Utilisation d'aminomethyle chromans a substitution dans le traitement de troubles des mouvements
DE10155075A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Cyclische Sulfonamide
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US7470798B2 (en) * 2003-09-19 2008-12-30 Edison Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
DE102004017627A1 (de) * 2004-04-10 2005-10-27 Bayer Healthcare Ag Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression
JP7187437B2 (ja) 2016-07-29 2022-12-12 サノビオン ファーマシューティカルズ インク 化合物および組成物ならびにそれらの使用
EP3490607A4 (fr) 2016-07-29 2020-04-08 Sunovion Pharmaceuticals Inc. Composés et compositions, et utilisations associées
RU2651756C1 (ru) * 2017-05-10 2018-04-23 Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ Препарат для предотвращения образования глиальных рубцов
SG11202000669VA (en) 2017-08-02 2020-02-27 Sunovion Pharmaceuticals Inc Isochroman compounds and uses thereof
KR20210139376A (ko) 2019-03-14 2021-11-22 선오비온 파마슈티컬스 인코포레이티드 이소크로마닐 화합물의 염, 및 이의 결정성 형태, 제조방법, 치료 용도 및 약제학적 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300523A (en) 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
GB9012316D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE19522088A1 (de) * 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Also Published As

Publication number Publication date
CN1279604A (zh) 2001-01-10
TW524690B (en) 2003-03-21
US6235774B1 (en) 2001-05-22
NZ504656A (en) 2002-02-01
KR20010032357A (ko) 2001-04-16
CA2311126A1 (fr) 1999-06-03
MY118414A (en) 2004-10-30
DE19751949A1 (de) 1999-05-27
PE134999A1 (es) 2000-03-05
US20010018530A1 (en) 2001-08-30
EP1051170B1 (fr) 2001-10-10
NO20002638D0 (no) 2000-05-23
SI1051170T1 (en) 2001-12-31
IL135904A0 (en) 2001-05-20
PT1051170E (pt) 2002-02-28
AU745759B2 (en) 2002-03-28
BG64167B1 (bg) 2004-03-31
IS5496A (is) 2000-05-15
ES2164465T3 (es) 2002-02-16
PL340674A1 (en) 2001-02-12
HUP0004369A2 (hu) 2001-04-28
SV1998000138A (es) 1999-05-25
IL135904A (en) 2003-07-06
TR200001471T2 (tr) 2000-10-23
CN1134256C (zh) 2004-01-14
RU2217140C2 (ru) 2003-11-27
EP1051170A1 (fr) 2000-11-15
WO1999026621A1 (fr) 1999-06-03
AU1668599A (en) 1999-06-15
JP2001523716A (ja) 2001-11-27
NO20002638L (no) 2000-05-23
ATE206615T1 (de) 2001-10-15
DE59801724D1 (de) 2001-11-15
HUP0004369A3 (en) 2002-04-29
BG104466A (en) 2001-02-28
US6331561B2 (en) 2001-12-18
HN1998000169A (es) 1999-11-03
ZA9810668B (en) 1999-05-26
AR016973A1 (es) 2001-08-01

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