DK1042353T3 - 17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater - Google Patents
17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivaterInfo
- Publication number
- DK1042353T3 DK1042353T3 DK98965821T DK98965821T DK1042353T3 DK 1042353 T3 DK1042353 T3 DK 1042353T3 DK 98965821 T DK98965821 T DK 98965821T DK 98965821 T DK98965821 T DK 98965821T DK 1042353 T3 DK1042353 T3 DK 1042353T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- independently hydrogen
- arylmethyl
- thio
- oxy
- Prior art date
Links
- 125000005002 aryl methyl group Chemical group 0.000 title 1
- -1 oxy (thio) Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 229910020008 S(O) Inorganic materials 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 229910004727 OSO3H Inorganic materials 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 230000021121 meiosis Effects 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
- C07J7/007—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified not substituted in position 17 alfa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97203998 | 1997-12-18 | ||
| PCT/EP1998/008130 WO1999032506A1 (fr) | 1997-12-18 | 1998-12-11 | DERIVES 17β-ARYL (ARYLMETHYL) OXY(THIO) ALKYLANDROSTANE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1042353T3 true DK1042353T3 (da) | 2002-11-04 |
Family
ID=8229080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98965821T DK1042353T3 (da) | 1997-12-18 | 1998-12-11 | 17-beta-aryl(arylmethyl)oxy(thio)alkylandrostanderivater |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6251887B1 (fr) |
| EP (1) | EP1042353B1 (fr) |
| JP (1) | JP2001526293A (fr) |
| AT (1) | ATE220686T1 (fr) |
| AU (1) | AU2160999A (fr) |
| DE (1) | DE69806640T2 (fr) |
| DK (1) | DK1042353T3 (fr) |
| ES (1) | ES2181321T3 (fr) |
| WO (1) | WO1999032506A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU759344B2 (en) * | 1998-12-11 | 2003-04-10 | Akzo Nobel N.V. | 22S-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity |
| AU5209600A (en) * | 1999-04-06 | 2000-10-23 | Akzo Nobel N.V. | Orally active androgens |
| AU2003280317A1 (en) * | 2002-11-14 | 2004-06-03 | Novo Nordisk A/S | Use of nuclear hormone receptors to identify meiosis regulating compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716777A (en) * | 1994-06-23 | 1998-02-10 | Novo Nordisk A/S | Regulation of meiosis using sterols |
| WO1996027658A1 (fr) | 1995-03-06 | 1996-09-12 | Novo Nordisk A/S | Stimulation de la meiose |
| JPH11507929A (ja) * | 1995-06-23 | 1999-07-13 | ノボ ノルディスク アクティーゼルスカブ | 減数分裂調節化合物 |
| DE69809905T2 (de) * | 1997-05-16 | 2003-08-28 | Akzo Nobel N.V., Arnheim/Arnhem | 20-aralkyl-5,alpha,-pregnan derivate |
| DK0988312T3 (da) * | 1997-06-04 | 2002-07-15 | Akzo Nobel Nv | 17beta-allyloxy(thio)alkyl-androstanderivater til modulering af meiose |
-
1998
- 1998-12-11 WO PCT/EP1998/008130 patent/WO1999032506A1/fr not_active Ceased
- 1998-12-11 EP EP98965821A patent/EP1042353B1/fr not_active Expired - Lifetime
- 1998-12-11 US US09/581,749 patent/US6251887B1/en not_active Expired - Fee Related
- 1998-12-11 DE DE69806640T patent/DE69806640T2/de not_active Expired - Fee Related
- 1998-12-11 AT AT98965821T patent/ATE220686T1/de not_active IP Right Cessation
- 1998-12-11 DK DK98965821T patent/DK1042353T3/da active
- 1998-12-11 ES ES98965821T patent/ES2181321T3/es not_active Expired - Lifetime
- 1998-12-11 AU AU21609/99A patent/AU2160999A/en not_active Abandoned
- 1998-12-11 JP JP2000525443A patent/JP2001526293A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999032506A1 (fr) | 1999-07-01 |
| AU2160999A (en) | 1999-07-12 |
| JP2001526293A (ja) | 2001-12-18 |
| DE69806640D1 (de) | 2002-08-22 |
| US6251887B1 (en) | 2001-06-26 |
| ES2181321T3 (es) | 2003-02-16 |
| EP1042353B1 (fr) | 2002-07-17 |
| EP1042353A1 (fr) | 2000-10-11 |
| ATE220686T1 (de) | 2002-08-15 |
| DE69806640T2 (de) | 2003-03-13 |
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