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DK1041997T3 - Use of citrullinated peptides derived from filaggrin for the treatment of autoimmune diseases - Google Patents

Use of citrullinated peptides derived from filaggrin for the treatment of autoimmune diseases

Info

Publication number
DK1041997T3
DK1041997T3 DK98964537T DK98964537T DK1041997T3 DK 1041997 T3 DK1041997 T3 DK 1041997T3 DK 98964537 T DK98964537 T DK 98964537T DK 98964537 T DK98964537 T DK 98964537T DK 1041997 T3 DK1041997 T3 DK 1041997T3
Authority
DK
Denmark
Prior art keywords
filaggrin
treatment
autoimmune diseases
peptides derived
citrullinated peptides
Prior art date
Application number
DK98964537T
Other languages
Danish (da)
Inventor
Guy Serre
Elisabeth Girbal-Neuhauser
Christian Vincent
Michel Simon
Mireille Sebbag
Pascal Dalbon
Colette Jolivet-Reynaud
Michel Arnaud
Michel Jolivet
Original Assignee
Univ Toulouse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toulouse filed Critical Univ Toulouse
Application granted granted Critical
Publication of DK1041997T3 publication Critical patent/DK1041997T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention concerns the use of a citrulline peptide antigen derived from filaggrin to obtain medicines for treating rheumatoid arthritis.
DK98964537T 1997-12-30 1998-12-29 Use of citrullinated peptides derived from filaggrin for the treatment of autoimmune diseases DK1041997T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9716672A FR2773078B1 (en) 1997-12-30 1997-12-30 USE OF CITRULLIN PEPTIDES DERIVED FROM FILAGGRIN FOR THE TREATMENT OF RHUMATOID POLYARTHRITIS
PCT/FR1998/002900 WO1999034819A2 (en) 1997-12-30 1998-12-29 Use of citrulline peptides derived from filaggrin for treating autoimmune diseases

Publications (1)

Publication Number Publication Date
DK1041997T3 true DK1041997T3 (en) 2003-08-04

Family

ID=9515271

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98964537T DK1041997T3 (en) 1997-12-30 1998-12-29 Use of citrullinated peptides derived from filaggrin for the treatment of autoimmune diseases

Country Status (10)

Country Link
EP (1) EP1041997B1 (en)
JP (1) JP4557421B2 (en)
AT (1) ATE237345T1 (en)
AU (1) AU1971899A (en)
CA (1) CA2315294C (en)
DE (1) DE69813620T2 (en)
DK (1) DK1041997T3 (en)
ES (1) ES2193601T3 (en)
FR (1) FR2773078B1 (en)
WO (1) WO1999034819A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2900657B1 (en) 2006-05-03 2009-04-17 Univ Toulouse IDENTIFICATION OF MACROPHAGE ACTIVATION MODULATORS, USEFUL FOR THE TREATMENT OF RHEUMATOID ARTHRITIS
FR2908134B1 (en) * 2007-12-04 2012-10-12 Univ Toulouse 3 Paul Sabatier IDENTIFICATION OF MACROPHAGE ACTIVATION MODULATORS, USEFUL FOR THE TREATMENT OF RHEUMATOID ARTHRITIS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7259691A (en) * 1990-01-31 1991-08-21 Board Of Regents Of The University Of Oklahoma, The Assays and treatments for autoimmune diseases
JP4162259B2 (en) * 1991-04-26 2008-10-08 ビオメリュー・ソシエテ・アノニム Antigen recognized by rheumatoid arthritis antibody, antigen preparation and application method thereof
AU6098994A (en) * 1993-01-27 1994-08-15 Duke University Methods and agents for the diagnosis and treatment of rheumatoid arthritis
FR2752842B1 (en) * 1996-08-30 1998-11-06 Biomerieux Sa ANTIGENS DERIVED FROM FILAGGRINS AND THEIR USE FOR THE DIAGNOSIS OF RHUMATOID POLYARTHRITIS
NL1004539C2 (en) * 1996-11-15 1998-05-20 Stichting Tech Wetenschapp Peptide derived from an antigen recognized by autoantibodies of patients with rheumatoid arthritis, antibody to it and method for detecting autoimmune antibodies.
AU2155899A (en) * 1997-11-28 1999-06-16 Innogenetics N.V. Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
FR2773157B1 (en) * 1997-12-30 2001-10-05 Bio Merieux PEPTIDE EPITOPES RECOGNIZED BY ANTIFILAGGRIN AUTOANTIBODIES PRESENT IN THE SERUM OF PATIENTS WITH RHUMATOID POLYARTHRITIS

Also Published As

Publication number Publication date
AU1971899A (en) 1999-07-26
DE69813620T2 (en) 2004-02-12
JP2002500195A (en) 2002-01-08
WO1999034819A2 (en) 1999-07-15
WO1999034819A3 (en) 1999-11-04
ES2193601T3 (en) 2003-11-01
FR2773078A1 (en) 1999-07-02
DE69813620D1 (en) 2003-05-22
ATE237345T1 (en) 2003-05-15
CA2315294C (en) 2012-07-03
JP4557421B2 (en) 2010-10-06
CA2315294A1 (en) 1999-07-15
EP1041997B1 (en) 2003-04-16
EP1041997A2 (en) 2000-10-11
FR2773078B1 (en) 2000-05-26

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