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DK0937090T3 - Fremgangsmåder til mærkning af nucleotider, mærkede nucleotider og nyttige mellemprodukter - Google Patents

Fremgangsmåder til mærkning af nucleotider, mærkede nucleotider og nyttige mellemprodukter

Info

Publication number
DK0937090T3
DK0937090T3 DK97943223T DK97943223T DK0937090T3 DK 0937090 T3 DK0937090 T3 DK 0937090T3 DK 97943223 T DK97943223 T DK 97943223T DK 97943223 T DK97943223 T DK 97943223T DK 0937090 T3 DK0937090 T3 DK 0937090T3
Authority
DK
Denmark
Prior art keywords
nucleotides
chain
spacer
labeling
moiety
Prior art date
Application number
DK97943223T
Other languages
Danish (da)
English (en)
Inventor
Hendrik Jan Houthoff
Jan Reedijk
Herman Hendricus Volkers
Tinka Jelsma
Robert Jochem Heetebrij
Original Assignee
Kreatech Biotech Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kreatech Biotech Bv filed Critical Kreatech Biotech Bv
Application granted granted Critical
Publication of DK0937090T3 publication Critical patent/DK0937090T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Inorganic Insulating Materials (AREA)
  • Medicinal Preparation (AREA)
  • Cold Cathode And The Manufacture (AREA)
DK97943223T 1996-10-08 1997-10-08 Fremgangsmåder til mærkning af nucleotider, mærkede nucleotider og nyttige mellemprodukter DK0937090T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96202792 1996-10-08
PCT/NL1997/000559 WO1998015564A1 (fr) 1996-10-08 1997-10-08 Procedes de marquage de nucleotides, nucleotides marques et intermediaires utiles

Publications (1)

Publication Number Publication Date
DK0937090T3 true DK0937090T3 (da) 2002-12-02

Family

ID=8224469

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97943223T DK0937090T3 (da) 1996-10-08 1997-10-08 Fremgangsmåder til mærkning af nucleotider, mærkede nucleotider og nyttige mellemprodukter

Country Status (12)

Country Link
US (4) USRE40557E1 (fr)
EP (1) EP0937090B1 (fr)
JP (2) JP4981197B2 (fr)
AT (1) ATE221894T1 (fr)
AU (1) AU726692B2 (fr)
CA (1) CA2267133C (fr)
DE (1) DE69714600T2 (fr)
DK (1) DK0937090T3 (fr)
ES (1) ES2182121T3 (fr)
NZ (1) NZ334803A (fr)
PT (1) PT937090E (fr)
WO (1) WO1998015564A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4981197B2 (ja) * 1996-10-08 2012-07-18 クレアテク バイオテクノロジー ベー．ファー． ヌクレオチドを標識付けする方法、標識ヌクレオチド及び有用な中間体
US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
EP1006199A1 (fr) * 1998-12-03 2000-06-07 Kreatech Biotechnology B.V. Procédé pour la production des réticulations à des points sélectionnés entre les brins d'acides nucléiques et leur utilisation
WO2001029265A1 (fr) * 1999-10-15 2001-04-26 Ventana Medical Systems, Inc. Procede de detection de copies uniques de gene in situ
US6376669B1 (en) * 1999-11-05 2002-04-23 3M Innovative Properties Company Dye labeled imidazoquinoline compounds
GB0016836D0 (en) 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
DE60213387D1 (de) 2001-03-02 2006-09-07 Stratagene California Zusammensetzungen und verfahren mit platinverbindungen zur nukleinsäuremarkierung
ATE376675T1 (de) * 2001-05-28 2007-11-15 Kreatech Biotech Bv Ein verfahren zur differentiellen markierung mittels platin-komplexen
US7166478B2 (en) * 2002-03-12 2007-01-23 Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses
EP1554402A4 (fr) * 2002-09-17 2006-06-28 Perkinelmer Life Sciences Inc Detection en temps reel des reactions d'acides nucleiques
US20050028450A1 (en) * 2003-08-07 2005-02-10 Wen-Qing Xu CMP slurry
US20060281100A1 (en) * 2005-06-14 2006-12-14 Shen Gene G Thiotriphosphate nucleotide dye terminators
EP1745802A1 (fr) 2005-07-20 2007-01-24 Kreatech Biotechnology B.V. Méthode pour conjuguer des composés thérapeutiques à des groupes pour cibles des cellules via des complexes de métaux.
US20090148958A1 (en) * 2006-04-27 2009-06-11 Onecell Inc. Nucleotide-transition metal complex catalyst
CN101970451A (zh) 2007-07-26 2011-02-09 塞雷公司 高度可见的染色体特异性探针及相关方法
KR101072900B1 (ko) * 2007-12-04 2011-10-17 주식회사 파나진 고정화된 펩티드핵산 프로브를 사용한 표적핵산의 선택적 표지 및 검출 방법
AU2013206976A1 (en) 2012-01-06 2014-07-24 Linxis B.V. Method for preparing cell targeting conjugates, and the complexes obtained
CN109030698B (zh) * 2018-08-06 2020-09-04 泰山医学院 一种液相色谱法检测固体福美钠纯度的方法
CN108760961B (zh) * 2018-08-06 2020-09-22 青岛中科荣达新材料有限公司 一种液相色谱法检测固体福美钾纯度的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207416A (en) * 1974-09-05 1980-06-10 Engelhard Minerals & Chemicals Corporation Ethylenediamineplatinum(II) 2,4-dioxopyrimidine complexes
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
DE3568063D1 (en) * 1985-01-10 1989-03-09 Molecular Diagnostics Inc Photochemical method of labelling nucleic acids for detection in hybridization assays
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
WO1989004317A1 (fr) * 1987-11-06 1989-05-18 Sagami Chemical Research Center Nouveaux complexes de platine (ii)
US5552541A (en) * 1990-06-20 1996-09-03 Beckman Instruments, Inc. Haptenic probes for detecting capture polynucleotides
NL9001639A (nl) * 1990-07-19 1992-02-17 Amc Amsterdam Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen.
US5714327A (en) * 1990-07-19 1998-02-03 Kreatech Diagnostics Platinum-containing compounds, methods for their preparation and applications thereof
DE69331319T2 (de) * 1992-06-09 2002-08-08 Neorx Corp., Seattle Biotin-DOTA Konjugate und deren Verwendung in "Pretargeting" Verfahren
JPH0698797A (ja) * 1992-09-22 1994-04-12 Toyobo Co Ltd 核酸検出法
DE4344742A1 (de) * 1993-06-09 1994-12-15 Boehringer Mannheim Gmbh Verfahren zur Immobilisierung von Nukleinsäuren
DE4326466A1 (de) * 1993-08-06 1995-02-09 Boehringer Mannheim Gmbh Infrarot-Farbstoff-markierte Nucleotide und ihre Verwendung in der Nucleinsäure-Detektion
NZ307633A (en) * 1995-05-09 2000-01-28 Kreatech Biotechnology Bv Methods for the production of platinum-based linkers between labels and bio-organic molecules, for labelling bio-organic molecules, for detecting
JP4981197B2 (ja) * 1996-10-08 2012-07-18 クレアテク バイオテクノロジー ベー．ファー． ヌクレオチドを標識付けする方法、標識ヌクレオチド及び有用な中間体

Also Published As

Publication number Publication date
EP0937090A1 (fr) 1999-08-25
US6797818B2 (en) 2004-09-28
EP0937090B1 (fr) 2002-08-07
DE69714600D1 (de) 2002-09-12
AU4474697A (en) 1998-05-05
ES2182121T3 (es) 2003-03-01
AU726692B2 (en) 2000-11-16
NZ334803A (en) 2000-05-26
US6338943B1 (en) 2002-01-15
US7217813B2 (en) 2007-05-15
PT937090E (pt) 2002-12-31
CA2267133C (fr) 2006-07-18
WO1998015564A1 (fr) 1998-04-16
CA2267133A1 (fr) 1998-04-16
JP2010166914A (ja) 2010-08-05
ATE221894T1 (de) 2002-08-15
US20050118621A1 (en) 2005-06-02
US20020160396A1 (en) 2002-10-31
JP4981197B2 (ja) 2012-07-18
DE69714600T2 (de) 2003-03-27
USRE40557E1 (en) 2008-10-28
JP2001503742A (ja) 2001-03-21

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