DK0921810T3 - Reduktionen af alvorligheden af vært versus transplantat reaktionen (HVGR) ved at nedregulere autoimmuniteten - Google Patents
Reduktionen af alvorligheden af vært versus transplantat reaktionen (HVGR) ved at nedregulere autoimmunitetenInfo
- Publication number
- DK0921810T3 DK0921810T3 DK97940708T DK97940708T DK0921810T3 DK 0921810 T3 DK0921810 T3 DK 0921810T3 DK 97940708 T DK97940708 T DK 97940708T DK 97940708 T DK97940708 T DK 97940708T DK 0921810 T3 DK0921810 T3 DK 0921810T3
- Authority
- DK
- Denmark
- Prior art keywords
- hvgr
- severity
- autoimmunity
- reducing
- downregulating
- Prior art date
Links
- 230000005784 autoimmunity Effects 0.000 title abstract 4
- 230000002222 downregulating effect Effects 0.000 title 1
- 108010058432 Chaperonin 60 Proteins 0.000 abstract 4
- 102000006303 Chaperonin 60 Human genes 0.000 abstract 4
- 230000003828 downregulation Effects 0.000 abstract 2
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000003614 tolerogenic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Marine Sciences & Fisheries (AREA)
- Food Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/706,209 US5993803A (en) | 1996-08-30 | 1996-08-30 | Method of reducing the severity of host vs graft reaction by down-regulating hsp60 autoimmunity |
| PCT/US1997/015294 WO1998008536A2 (fr) | 1996-08-30 | 1997-09-02 | Methode de reduction de la gravite d'une reaction de l'hote contre le greffon par regulation negative de l'autoimmunite vis-a-vis de hsp60 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0921810T3 true DK0921810T3 (da) | 2003-07-28 |
Family
ID=24836651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97940708T DK0921810T3 (da) | 1996-08-30 | 1997-09-02 | Reduktionen af alvorligheden af vært versus transplantat reaktionen (HVGR) ved at nedregulere autoimmuniteten |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5993803A (fr) |
| EP (1) | EP0921810B1 (fr) |
| JP (1) | JP4256474B2 (fr) |
| AT (1) | ATE237344T1 (fr) |
| AU (1) | AU722576B2 (fr) |
| CA (1) | CA2263816C (fr) |
| DE (1) | DE69721007T2 (fr) |
| DK (1) | DK0921810T3 (fr) |
| ES (1) | ES2198594T3 (fr) |
| IL (2) | IL128728A0 (fr) |
| WO (1) | WO1998008536A2 (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9911772D0 (en) * | 1999-05-21 | 1999-07-21 | Semmelweis University Of Medic | Diagnosis and treatment of atherosclerosis |
| IL150113A0 (en) * | 1999-12-15 | 2002-12-01 | Peptor Ltd | Fragments and antagonists of heat shock protein 60 |
| AU784623B2 (en) * | 1999-12-15 | 2006-05-18 | Develogen Israel Ltd. | Fragments and antagonists of heat shock protein 60 |
| AU2001249214A1 (en) * | 2000-03-15 | 2001-09-24 | The Brigham And Women's Hospital, Inc. | Suppression of vascular disorders by mucosal administration of heat shock protein peptides |
| US7608683B2 (en) * | 2000-08-09 | 2009-10-27 | The Regents Of The University Of California | Stress proteins and peptides and methods of use thereof |
| US6989146B2 (en) * | 2000-08-09 | 2006-01-24 | The Regents Of The University Of California | Stress proteins and peptides and methods of use thereof |
| CA2420499A1 (fr) * | 2000-08-25 | 2002-02-28 | Yeda Research And Development Co. Ltd. | Procedes de traitement ou de prevention de maladies auto-immunes au moyen d'un polynucleotide renfermant du cpg |
| WO2002036611A2 (fr) | 2000-11-01 | 2002-05-10 | The Regents Of The University Of California | Peptides immunomodulateurs derives de proteines de choc thermique et leur utilisations |
| WO2003063759A2 (fr) | 2002-01-31 | 2003-08-07 | Peptor Ltd. | Peptides de hsp et analogues pour la modulation des reponses immunitaires par l'intermediaire des cellules presentant l'antigene |
| AU2003209623A1 (en) * | 2002-02-19 | 2003-09-09 | Yeda Research And Development Co. Ltd. | Dual-effect ligands comprising anti-inflammatory hsp peptide epitopes for immunomodulation |
| EP2301566B1 (fr) | 2002-05-21 | 2013-07-03 | Irun R. Cohen | Vaccin d'ADN codant pour les protéines de choc thermique |
| WO2004090095A2 (fr) * | 2003-04-01 | 2004-10-21 | University Of Southern California | Generation de lymphocytes t regulateurs humains par des toxines bacteriennes pour traiter des troubles inflammatoires |
| CA2547079A1 (fr) * | 2003-11-24 | 2005-06-02 | Yeda Research & Development Co. Ltd. | Vaccins d'adn codant pour des fragments de peptide hsp60 permettant de traiter les maladies auto-immunes |
| WO2005072056A2 (fr) * | 2004-01-28 | 2005-08-11 | Develogen Israel Ltd. | Therapie hsp associee a un regime a faible antigenicite |
| CU23504A1 (es) | 2004-09-24 | 2010-04-13 | Ct Ingenieria Genetica Biotech | Péptidos y derivados tipo apl de la hsp60 y composiciones farmacéuticas |
| EP1835933A4 (fr) * | 2005-01-04 | 2015-01-07 | Yeda Res & Dev | Hsp60, peptides hsp60 et vaccins a base de lymphocytes t pour immunomodulation |
| WO2013128453A1 (fr) | 2012-03-01 | 2013-09-06 | Yeda Research And Development Co. Ltd. | Régénération de cellules bêta des îlots de langerhans par des peptides dérivés de hsp60 |
| CN104244967A (zh) | 2012-03-01 | 2014-12-24 | 耶达研究与发展有限公司 | 用于抑制和治疗非自身免疫性糖尿病的Hsp60衍生肽和肽类似物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL92629A0 (en) * | 1989-12-10 | 1990-08-31 | Yeda Res & Dev | Direct binding of t-cell epitopes to mhc gene products on intact living antigen presenting cells and the use thereof for identifying epitopes causing autoimmune diseases and pharmaceutical compositions for treating such diseases |
| WO1992004049A1 (fr) * | 1990-09-06 | 1992-03-19 | Rijksuniversiteit Te Utrecht | Inhibiteurs de la reponse de lymphocytes et de maladies immunitaires |
| IL114407A0 (en) * | 1995-06-30 | 1995-10-31 | Yeda Res & Dev | Novel peptides and pharmaceutical compositions comprising them |
| IL114458A0 (en) * | 1995-07-05 | 1995-11-27 | Yeda Res & Dev | Therapeutic preparations for treatment of T cell mediated diseases |
-
1996
- 1996-08-30 US US08/706,209 patent/US5993803A/en not_active Expired - Lifetime
-
1997
- 1997-09-02 AT AT97940708T patent/ATE237344T1/de not_active IP Right Cessation
- 1997-09-02 IL IL12872897A patent/IL128728A0/xx active IP Right Grant
- 1997-09-02 DE DE69721007T patent/DE69721007T2/de not_active Expired - Lifetime
- 1997-09-02 WO PCT/US1997/015294 patent/WO1998008536A2/fr not_active Ceased
- 1997-09-02 CA CA002263816A patent/CA2263816C/fr not_active Expired - Fee Related
- 1997-09-02 DK DK97940708T patent/DK0921810T3/da active
- 1997-09-02 ES ES97940708T patent/ES2198594T3/es not_active Expired - Lifetime
- 1997-09-02 AU AU42426/97A patent/AU722576B2/en not_active Ceased
- 1997-09-02 EP EP97940708A patent/EP0921810B1/fr not_active Expired - Lifetime
- 1997-09-02 JP JP51198498A patent/JP4256474B2/ja not_active Expired - Fee Related
-
1999
- 1999-02-25 IL IL128728A patent/IL128728A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0921810A2 (fr) | 1999-06-16 |
| IL128728A0 (en) | 2000-01-31 |
| US5993803A (en) | 1999-11-30 |
| ATE237344T1 (de) | 2003-05-15 |
| WO1998008536A2 (fr) | 1998-03-05 |
| CA2263816A1 (fr) | 1998-03-05 |
| AU722576B2 (en) | 2000-08-10 |
| ES2198594T3 (es) | 2004-02-01 |
| CA2263816C (fr) | 2008-12-30 |
| IL128728A (en) | 2006-09-05 |
| JP4256474B2 (ja) | 2009-04-22 |
| EP0921810B1 (fr) | 2003-04-16 |
| JP2001500488A (ja) | 2001-01-16 |
| WO1998008536A3 (fr) | 1998-05-07 |
| DE69721007T2 (de) | 2004-02-12 |
| AU4242697A (en) | 1998-03-19 |
| DE69721007D1 (de) | 2003-05-22 |
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