DK0915864T3 - Gastrobeskyttende flavon/flavanonforbindelser med terapeutisk virkning på inflammatoriske tarmsygdomme - Google Patents

Gastrobeskyttende flavon/flavanonforbindelser med terapeutisk virkning på inflammatoriske tarmsygdomme

Info

Publication number: DK0915864T3
Authority: DK; Denmark
Prior art keywords: gastroprotective; flavone; therapeutic effect; inflammatory bowel; bowel diseases
Prior art date: 1996-07-25

Application number

DK97932032T

Other languages

English (en)

Inventor

Moohi Yoo

Mi Won Imkwang Apt - Son

Ik Yon - Naeyou-Dong Deoky Kim

Won Bae Hyundai Apt - Kaep Kim

Soon Hoe Jookong Apt - Kim

Sang Deuk Eunma Apt - Daec Lee

Geun Jho Myoungsodae Hyund Lim

Joong In Lim

Byoung Ok Ahn

Nam Gi Baik

Dong Sung Kim

Tae Young Oh

Byung Kwon Ryu

Jae Sung Yang

Hee Chan Shin

Original Assignee

Dong A Pharm Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-25

Filing date

1997-07-25

Publication date

2002-12-30

1997-07-25 Application filed by Dong A Pharm Co Ltd filed Critical Dong A Pharm Co Ltd

2002-12-30 Application granted granted Critical

2002-12-30 Publication of DK0915864T3 publication Critical patent/DK0915864T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/32—2,3-Dihydro derivatives, e.g. flavanones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)

DK97932032T 1996-07-25 1997-07-25 Gastrobeskyttende flavon/flavanonforbindelser med terapeutisk virkning på inflammatoriske tarmsygdomme DK0915864T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR1019960030494A KR100447918B1 (ko)	1996-07-25	1996-07-25	대장을포함한위장관보호작용을갖는플라본및플라바논화합물
PCT/KR1997/000144 WO1998004541A1 (en)	1996-07-25	1997-07-25	Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease

Publications (1)

Publication Number	Publication Date
DK0915864T3 true DK0915864T3 (da)	2002-12-30

Family

ID=19467593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97932032T DK0915864T3 (da)	1996-07-25	1997-07-25	Gastrobeskyttende flavon/flavanonforbindelser med terapeutisk virkning på inflammatoriske tarmsygdomme

Country Status (8)

Country	Link
US (1)	US6025387A (da)
EP (1)	EP0915864B1 (da)
JP (1)	JP3377214B2 (da)
KR (1)	KR100447918B1 (da)
CA (1)	CA2261267C (da)
DE (1)	DE69715216T2 (da)
DK (1)	DK0915864T3 (da)
WO (1)	WO1998004541A1 (da)

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US7638554B2 (en) *	2002-04-18	2009-12-29	Sri International	Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
US20030229136A1 (en) *	2002-04-18	2003-12-11	Nurulain Zaveri	Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
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JP2008504292A (ja)	2004-06-24	2008-02-14	ノバルティスヴァクシンズアンドダイアグノスティクス，インコーポレイテッド	免疫増強用の化合物
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US20090042818A1 (en) *	2007-06-22	2009-02-12	Bionovo, Inc.	Liquiritigenin and Derivatives as Selective Estrogen Receptor Beta Agonists
US20080319051A1 (en) *	2007-06-22	2008-12-25	Bionovo, Inc.	Liquiritigenin and derivatives as selective estrogen receptor beta agonists
KR101381999B1 (ko) *	2007-07-06	2014-04-14	동아에스티 주식회사	위염 치료제의 효력을 극대화시키기 위한 가용화 위체류시스템 매트릭스 제제
KR101391494B1 (ko)	2007-11-26	2014-05-07	동아에스티 주식회사	위염 치료제의 효력을 극대화시키기 위한 나노서스펜젼
EA201000947A1 (ru)	2007-12-20	2011-02-28	Новартис Аг	Производные тиазола, применимые в качестве ингибиторов киназы pi3
WO2009110008A1 (en) *	2008-03-05	2009-09-11	Council Of Scientific & Industrial Research	Anti-ulcer activity of flavone analogs
EP2112145A1 (en) *	2008-04-24	2009-10-28	AxoGlia Therapeutics S.A.	Chromenone derivatives useful for the treatment of neurodegenerative diseases
US8293753B2 (en)	2009-07-02	2012-10-23	Novartis Ag	Substituted 2-carboxamide cycloamino ureas
AR082418A1 (es)	2010-08-02	2012-12-05	Novartis Ag	Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
JP5712580B2 (ja) *	2010-11-30	2015-05-07	株式会社ツムラ	５，７‐ジヒドロキシ‐６‐メトキシフラボン類の製造方法
US8987257B2 (en)	2011-01-31	2015-03-24	Novartis Ag	Heterocyclic derivatives
KR20140090218A (ko)	2011-10-28	2014-07-16	노파르티스 아게	신규 퓨린 유도체 및 질환의 치료에서의 그의 용도
HK1202435A1 (en)	2012-05-16	2015-10-02	Novartis Ag	Dosage regimen for a pi-3 kinase inhibitor
MX378409B (es)	2013-12-06	2025-03-10	Novartis Ag	Regimen de dosificacion para un inhibidor selectivo alfa-isomorfo de fosfatidilinositol 3-quinasa.
CN107072979B (zh) *	2014-09-05	2021-05-18	合一生技股份有限公司	类黄酮化合物在制备伤口愈合组合物的用途
WO2017077445A1 (en)	2015-11-02	2017-05-11	Novartis Ag	Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
WO2018060833A1 (en)	2016-09-27	2018-04-05	Novartis Ag	Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
CN111374971A (zh) *	2020-04-26	2020-07-07	南开大学	香叶木素在制备用于治疗炎症性肠病的药物中的应用
CN111454240B (zh) *	2020-04-30	2023-05-16	上海爱启医药技术有限公司	制备二硒醚化合物的方法
CN115197191A (zh) *	2021-04-09	2022-10-18	中国海洋大学	一种新型中药黄酮衍生物及其制备方法和应用
CN115197190A (zh) *	2021-04-09	2022-10-18	中国海洋大学	一种新型植物黄酮衍生物及其制备方法和应用
KR102583151B1 (ko)	2021-08-05	2023-09-26	지엘팜텍주식회사	안구건조증 치료를 위한 레코플라본 함유 점안 조성물 및 이의 제조방법
KR102356603B1 (ko)	2021-08-05	2022-02-08	지엘팜텍주식회사	안구건조증 치료를 위한 레코플라본 함유 점안 조성물
US20250082603A1 (en)	2021-08-05	2025-03-13	Gl Pharmtech Corp.	Ophthalmic composition containing recoflavone for the treatment of dry eye disease and method for preparing the same

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1996
- 1996-07-25 KR KR1019960030494A patent/KR100447918B1/ko not_active Expired - Lifetime
1997
- 1997-07-25 DK DK97932032T patent/DK0915864T3/da active
- 1997-07-25 DE DE69715216T patent/DE69715216T2/de not_active Expired - Lifetime
- 1997-07-25 WO PCT/KR1997/000144 patent/WO1998004541A1/en not_active Ceased
- 1997-07-25 CA CA002261267A patent/CA2261267C/en not_active Expired - Fee Related
- 1997-07-25 JP JP50871298A patent/JP3377214B2/ja not_active Expired - Fee Related
- 1997-07-25 US US09/214,889 patent/US6025387A/en not_active Expired - Lifetime
- 1997-07-25 EP EP97932032A patent/EP0915864B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0915864B1 (en)	2002-09-04
KR100447918B1 (ko)	2005-09-28
DE69715216T2 (de)	2003-05-08
DE69715216D1 (de)	2002-10-10
JP3377214B2 (ja)	2003-02-17
WO1998004541A1 (en)	1998-02-05
CA2261267C (en)	2003-10-07
CA2261267A1 (en)	1998-02-05
JPH11514015A (ja)	1999-11-30
US6025387A (en)	2000-02-15
EP0915864A1 (en)	1999-05-19

Publication	Publication Date	Title
DK0915864T3 (da)	2002-12-30	Gastrobeskyttende flavon/flavanonforbindelser med terapeutisk virkning på inflammatoriske tarmsygdomme
EE9900506A (et)	2000-06-15	Asendatud bensopüraani derivaadid põletiku raviks
IS2277B (is)	2007-09-15	Meðferðarlegar bíarýl afleiður
DE69401763D1 (de)	1997-03-27	Chondroprotektive Flavone
NO950879D0 (no)	1995-03-07	3-fenylpyrrolidin-derivater
IS4864A (is)	1998-10-13	Karbólín afleiður
NO20021400D0 (no)	2002-03-20	Terapeutiske konazolinderivater
NO307608B1 (no)	2000-05-02	Purinderivater og suppresjonspreparater for inflammasjonssykdommer
BR9708585A (pt)	1999-08-03	Forma de dosagem sólida Ph-independente de liberação imediata da cisaprida
TR199600497A2 (tr)	1997-01-21	Iltihapli bagirsak hastaliklari icin Kappa-Opiatagonistleri.
EE200000140A (et)	2001-02-15	Asendatud kromaani derivaadid
NO991560L (no)	1999-06-02	PDE IV-inhiberende 2-cyanoiminoimidazol-derivater
EE200000144A (et)	2001-02-15	Asendatud kromaani derivaadid
PT983275E (pt)	2003-01-31	Novos derivados do triptolido vantajosos para o tratamento de doencas autoimunes
NO970881D0 (no)	1997-02-27	Krystallinsk D-vitaminderivat
DE69700887D1 (de)	2000-01-13	Isoprenderivate
DK0739892T3 (da)	2003-01-20	Chromonderivater
NO922521D0 (no)	1992-06-26	Piperidinyletanolderivater med terapeutisk virkning
FI963754L (fi)	1996-09-20	D-vitamiinijohdannaisia
KR960008525A (ko)	1996-03-22	캐시 열 타이밍 제어장치
DK1102746T3 (da)	2003-09-08	Substituerede phenylamidiner med antitrombotisk virkning
EE200300194A (et)	2003-08-15	Asendatud bensopüraani derivaatide kasutamine põletiku raviks
KR970056867U (ko)	1997-11-10	따뜻한 변기
SE9501926L (sv)	1995-12-09	Underbyxor
KR970050816U (ko)	1997-09-08	보온침대