DK0954290T3 - Farmaceutisk tablet med kontrolleret frigivelse indeholdende en bærer baseret på tværbundet amylose og hydroxypropylmethylcellulose - Google Patents
Farmaceutisk tablet med kontrolleret frigivelse indeholdende en bærer baseret på tværbundet amylose og hydroxypropylmethylcelluloseInfo
- Publication number
- DK0954290T3 DK0954290T3 DK97915220T DK97915220T DK0954290T3 DK 0954290 T3 DK0954290 T3 DK 0954290T3 DK 97915220 T DK97915220 T DK 97915220T DK 97915220 T DK97915220 T DK 97915220T DK 0954290 T3 DK0954290 T3 DK 0954290T3
- Authority
- DK
- Denmark
- Prior art keywords
- cross
- linked amylose
- tablet containing
- hydroxypropylmethylcellulose
- controlled
- Prior art date
Links
- 229920000856 Amylose Polymers 0.000 title abstract 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 title abstract 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 title abstract 3
- 238000013270 controlled release Methods 0.000 title abstract 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 title 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 229940088598 enzyme Drugs 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 102000004139 alpha-Amylases Human genes 0.000 abstract 1
- 108090000637 alpha-Amylases Proteins 0.000 abstract 1
- 229940024171 alpha-amylase Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000000968 intestinal effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002173818A CA2173818A1 (fr) | 1996-04-10 | 1996-04-10 | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
| PCT/CA1997/000229 WO1997037639A1 (fr) | 1996-04-10 | 1997-04-04 | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0954290T3 true DK0954290T3 (da) | 2003-09-22 |
Family
ID=4157953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97915220T DK0954290T3 (da) | 1996-04-10 | 1997-04-04 | Farmaceutisk tablet med kontrolleret frigivelse indeholdende en bærer baseret på tværbundet amylose og hydroxypropylmethylcellulose |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5885615A (xx) |
| EP (1) | EP0954290B1 (xx) |
| JP (1) | JP4166278B2 (xx) |
| KR (1) | KR100439614B1 (xx) |
| CN (1) | CN1218396A (xx) |
| AT (1) | ATE240719T1 (xx) |
| AU (1) | AU711089B2 (xx) |
| BR (1) | BR9708772A (xx) |
| CA (1) | CA2173818A1 (xx) |
| CZ (1) | CZ294342B6 (xx) |
| DE (1) | DE69722247T2 (xx) |
| DK (1) | DK0954290T3 (xx) |
| ES (1) | ES2200166T3 (xx) |
| IL (1) | IL126477A (xx) |
| MY (1) | MY115535A (xx) |
| NO (1) | NO321862B1 (xx) |
| NZ (1) | NZ332576A (xx) |
| PL (1) | PL187764B1 (xx) |
| PT (1) | PT954290E (xx) |
| TR (1) | TR199802034T2 (xx) |
| WO (1) | WO1997037639A1 (xx) |
| ZA (1) | ZA973054B (xx) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ260408A (en) | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
| US6197339B1 (en) | 1997-09-30 | 2001-03-06 | Pharmacia & Upjohn Company | Sustained release tablet formulation to treat Parkinson's disease |
| US6284273B1 (en) * | 1998-02-24 | 2001-09-04 | Vincent Lenaerts | Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds |
| WO2000033818A1 (en) | 1998-12-11 | 2000-06-15 | Nostrum Pharmaceuticals, Inc. | Sustained release tablet containing hydrocolloid and cellulose ether |
| US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
| EP1174127A1 (en) * | 2000-07-21 | 2002-01-23 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Composition for targeted release of an actvie substance and process for producing such a composition |
| US6673369B2 (en) * | 2001-08-29 | 2004-01-06 | Ranbaxy Laboratories Limited | Controlled release formulation |
| AU2003225837B2 (en) * | 2002-03-15 | 2008-11-06 | Forest Laboratories Holdings Limited | NE and 5-HT reuptake inhibitors for treating visceral pain syndromes |
| US20060003004A1 (en) * | 2002-10-25 | 2006-01-05 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| MY142195A (en) * | 2002-10-25 | 2010-10-15 | Labopharm Inc | Controlled-release compositions |
| US8487002B2 (en) * | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
| US20040132826A1 (en) * | 2002-10-25 | 2004-07-08 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
| CA2503361C (en) * | 2002-10-25 | 2012-02-28 | Labopharm Inc. | Controlled-release compositions |
| TWI319713B (en) * | 2002-10-25 | 2010-01-21 | Sustained-release tramadol formulations with 24-hour efficacy | |
| EP1578281A2 (en) * | 2002-11-25 | 2005-09-28 | Boston Scientific Limited | Injection device for treating mammalian body |
| US20040228830A1 (en) * | 2003-01-28 | 2004-11-18 | Collegium Pharmaceutical, Inc. | Multiparticulate compositions of milnacipran for oral administration |
| US20060172006A1 (en) * | 2003-10-10 | 2006-08-03 | Vincent Lenaerts | Sustained-release tramadol formulations with 24-hour clinical efficacy |
| AR051654A1 (es) * | 2004-11-04 | 2007-01-31 | Astrazeneca Ab | Nuevas formulaciones de pellets de liberacion modificada para inhibidores de la bomba de protones |
| CA2491665A1 (fr) * | 2004-12-24 | 2006-06-24 | Louis Cartilier | Formulation de comprime pour liberation soutenue de principe actif |
| CN101252932B (zh) * | 2005-09-09 | 2012-10-03 | 安吉利尼莱博法姆有限责任公司 | 用于一天给药一次的曲唑酮组合物 |
| RU2008113439A (ru) * | 2005-09-09 | 2009-10-20 | Лабофарм Инк. (CA) | Композиции с замедленным высвобождением лекарственного средства |
| ATE540705T1 (de) * | 2005-09-21 | 2012-01-15 | Surmodics Inc | Überzüge und artikel mit natürlichen biologisch abbaubaren polysacchariden |
| WO2007035865A1 (en) * | 2005-09-21 | 2007-03-29 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
| WO2007055329A1 (ja) * | 2005-11-11 | 2007-05-18 | Asahi Kasei Chemicals Corporation | 徐放性固形製剤 |
| US20080154241A1 (en) * | 2006-12-07 | 2008-06-26 | Burkstrand Michael J | Latent stabilization of bioactive agents releasable from implantable medical articles |
| CA2723192A1 (en) | 2008-05-07 | 2009-11-12 | Surmodics, Inc. | Delivery of nucleic acid complexes from particles |
| US20100056540A1 (en) * | 2008-09-04 | 2010-03-04 | Bristol-Myers Squibb Company | Stable pharmaceutical composition for optimized delivery of an hiv attachment inhibitor |
| AU2009320181B2 (en) * | 2008-10-27 | 2015-08-27 | Alza Corporation | Extended release oral acetaminophen/tramadol dosage form |
| US20100260842A1 (en) * | 2009-04-06 | 2010-10-14 | Rashmi Nair | Pseudoephedrine pharmaceutical formulations |
| US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3065143A (en) * | 1960-04-19 | 1962-11-20 | Richardson Merrell Inc | Sustained release tablet |
| US4167558A (en) * | 1976-02-13 | 1979-09-11 | Hoffmann-La Roche Inc. | Novel sustained release tablet formulations |
| US4389393A (en) * | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
| US4610870A (en) * | 1984-10-05 | 1986-09-09 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| US4734285A (en) * | 1985-10-28 | 1988-03-29 | The Dow Chemical Company | Sustained release compositions |
| US4704285A (en) * | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
| US4775535A (en) * | 1986-04-04 | 1988-10-04 | Hans Lowey | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| US4855143A (en) * | 1986-04-04 | 1989-08-08 | Hans Lowey | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| CA2041774C (en) * | 1990-11-27 | 1994-04-19 | Mircea A. Mateescu | Use of cross-linked amylose as a matrix for the slow release of biologically active compounds |
| US5603956A (en) * | 1990-11-27 | 1997-02-18 | Labopharm Inc. | Cross-linked enzymatically controlled drug release |
| NL9201196A (nl) * | 1992-07-03 | 1994-02-01 | Tno | Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat. |
| AU668198B2 (en) * | 1992-07-24 | 1996-04-26 | Labopharm (Barbados) Limited | Cross-linked polyhydroxylic material for enzymatically controlled drug release |
| US5616343A (en) * | 1993-03-25 | 1997-04-01 | Labopharm, Inc. | Cross-linked amylose as a binder/disintegrant in tablets |
| IT1282650B1 (it) * | 1996-02-19 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici |
-
1996
- 1996-04-10 CA CA002173818A patent/CA2173818A1/fr not_active Abandoned
- 1996-08-19 US US08/699,611 patent/US5885615A/en not_active Expired - Lifetime
-
1997
- 1997-04-04 AT AT97915220T patent/ATE240719T1/de active
- 1997-04-04 JP JP53470597A patent/JP4166278B2/ja not_active Expired - Fee Related
- 1997-04-04 IL IL12647797A patent/IL126477A/en not_active IP Right Cessation
- 1997-04-04 PL PL32928597A patent/PL187764B1/pl unknown
- 1997-04-04 DK DK97915220T patent/DK0954290T3/da active
- 1997-04-04 CZ CZ19983254A patent/CZ294342B6/cs not_active IP Right Cessation
- 1997-04-04 WO PCT/CA1997/000229 patent/WO1997037639A1/fr not_active Ceased
- 1997-04-04 TR TR1998/02034T patent/TR199802034T2/xx unknown
- 1997-04-04 PT PT97915220T patent/PT954290E/pt unknown
- 1997-04-04 CN CN97194638A patent/CN1218396A/zh active Pending
- 1997-04-04 AU AU22832/97A patent/AU711089B2/en not_active Ceased
- 1997-04-04 DE DE69722247T patent/DE69722247T2/de not_active Expired - Lifetime
- 1997-04-04 BR BR9708772-6A patent/BR9708772A/pt not_active IP Right Cessation
- 1997-04-04 ES ES97915220T patent/ES2200166T3/es not_active Expired - Lifetime
- 1997-04-04 KR KR10-1998-0708056A patent/KR100439614B1/ko not_active Expired - Fee Related
- 1997-04-04 NZ NZ332576A patent/NZ332576A/xx not_active IP Right Cessation
- 1997-04-04 EP EP97915220A patent/EP0954290B1/fr not_active Expired - Lifetime
- 1997-04-10 MY MYPI97001576A patent/MY115535A/en unknown
- 1997-04-10 ZA ZA9703054A patent/ZA973054B/xx unknown
-
1998
- 1998-10-08 NO NO19984703A patent/NO321862B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000005337A (ko) | 2000-01-25 |
| US5885615A (en) | 1999-03-23 |
| PT954290E (pt) | 2003-10-31 |
| PL187764B1 (pl) | 2004-10-29 |
| EP0954290B1 (fr) | 2003-05-21 |
| DE69722247T2 (de) | 2004-04-01 |
| JP2000507561A (ja) | 2000-06-20 |
| MY115535A (en) | 2003-07-31 |
| ATE240719T1 (de) | 2003-06-15 |
| PL329285A1 (en) | 1999-03-15 |
| CN1218396A (zh) | 1999-06-02 |
| EP0954290A1 (fr) | 1999-11-10 |
| TR199802034T2 (xx) | 1999-02-22 |
| CA2173818A1 (fr) | 1997-10-11 |
| NO321862B1 (no) | 2006-07-17 |
| BR9708772A (pt) | 2000-01-04 |
| IL126477A0 (en) | 1999-08-17 |
| JP4166278B2 (ja) | 2008-10-15 |
| AU2283297A (en) | 1997-10-29 |
| CZ294342B6 (cs) | 2004-12-15 |
| IL126477A (en) | 2001-10-31 |
| ZA973054B (en) | 1998-06-01 |
| AU711089B2 (en) | 1999-10-07 |
| NO984703D0 (no) | 1998-10-08 |
| NO984703L (no) | 1998-12-08 |
| CZ325498A3 (cs) | 1999-03-17 |
| ES2200166T3 (es) | 2004-03-01 |
| NZ332576A (en) | 2000-03-27 |
| DE69722247D1 (de) | 2003-06-26 |
| WO1997037639A1 (fr) | 1997-10-16 |
| KR100439614B1 (ko) | 2004-10-14 |
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