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DK0819112T3 - Oxidativ fremgangsmåde til fremstilling af narwedinderivater - Google Patents

Oxidativ fremgangsmåde til fremstilling af narwedinderivater

Info

Publication number
DK0819112T3
DK0819112T3 DK96908286T DK96908286T DK0819112T3 DK 0819112 T3 DK0819112 T3 DK 0819112T3 DK 96908286 T DK96908286 T DK 96908286T DK 96908286 T DK96908286 T DK 96908286T DK 0819112 T3 DK0819112 T3 DK 0819112T3
Authority
DK
Denmark
Prior art keywords
preparation
compound
formula
oxidative process
narwedine
Prior art date
Application number
DK96908286T
Other languages
Danish (da)
English (en)
Inventor
James Chiroscience Henshilwood
Nicholas Bernard Johnson
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of DK0819112T3 publication Critical patent/DK0819112T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DK96908286T 1995-04-03 1996-04-02 Oxidativ fremgangsmåde til fremstilling af narwedinderivater DK0819112T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9506843.3A GB9506843D0 (en) 1995-04-03 1995-04-03 Oxidative process and products thereof
PCT/GB1996/000815 WO1996031458A1 (fr) 1995-04-03 1996-04-02 Procede oxydatif pour la preparation de derives de narwedine

Publications (1)

Publication Number Publication Date
DK0819112T3 true DK0819112T3 (da) 2002-04-29

Family

ID=10772408

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96908286T DK0819112T3 (da) 1995-04-03 1996-04-02 Oxidativ fremgangsmåde til fremstilling af narwedinderivater

Country Status (12)

Country Link
US (2) US6084094A (fr)
EP (1) EP0819112B1 (fr)
AT (1) ATE213228T1 (fr)
AU (1) AU716794B2 (fr)
CA (1) CA2215633C (fr)
DE (1) DE69619230T2 (fr)
DK (1) DK0819112T3 (fr)
ES (1) ES2171661T3 (fr)
GB (1) GB9506843D0 (fr)
PT (1) PT819112E (fr)
WO (1) WO1996031458A1 (fr)
ZA (1) ZA962677B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
AU2004276354B2 (en) * 2003-09-26 2009-07-09 Scinopharm Taiwan, Ltd. Resolution of a narwedine amide derivative
WO2005065661A2 (fr) * 2003-12-31 2005-07-21 Actavis Group Hf Formulations de galantamine
US20050142193A1 (en) * 2003-12-31 2005-06-30 Lijuan Tang Galantamine formulations
US20080306257A1 (en) * 2005-05-03 2008-12-11 Medichem, S.A. Syntheses and Preparations of Narwedine and Related Novel Compounds
US7985879B2 (en) 2007-04-12 2011-07-26 Scinopharm Taiwan Ltd. Process for making galantamine
RU2717644C2 (ru) 2014-03-07 2020-03-24 ДиЭнЭй ГЕНОТЕК ИНК. Способ, композиция и набор для стабилизации дезоксирибонуклеиновых кислот в биологических образцах
CN104592243B (zh) * 2014-12-19 2016-08-24 北京大学 加兰他敏和力克拉敏的不对称合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122665B1 (en) * 1978-11-21 1982-08-31 Edinen Zentar Chim Process for preparing novel dienones of narvedine type and their derivatives
US4290862A (en) * 1979-11-14 1981-09-22 Edinen Centar P Chimia Method for the preparation of narwedine-type enones
JP2755403B2 (ja) 1987-05-04 1998-05-20 デイービス、ボニー アルツハイマー病の治療のための化合物
AT401058B (de) 1994-10-21 1996-06-25 Waldheim Pharmazeutika Gmbh Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
US6018043A (en) * 1995-04-06 2000-01-25 Janssen Pharmaceutica, N.V. Process for preparing galanthamine derivatives by asymmetric reduction

Also Published As

Publication number Publication date
ATE213228T1 (de) 2002-02-15
PT819112E (pt) 2002-07-31
AU716794B2 (en) 2000-03-09
EP0819112A1 (fr) 1998-01-21
CA2215633C (fr) 2007-07-31
WO1996031458A1 (fr) 1996-10-10
DE69619230T2 (de) 2002-09-19
ZA962677B (en) 1997-04-03
US6084094A (en) 2000-07-04
US6271371B1 (en) 2001-08-07
CA2215633A1 (fr) 1996-10-10
EP0819112B1 (fr) 2002-02-13
DE69619230D1 (de) 2002-03-21
AU5159596A (en) 1996-10-23
GB9506843D0 (en) 1995-05-24
ES2171661T3 (es) 2002-09-16

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