DK0815074T3 - O-carbamoyl-(D)-phenylalaniforbindelser og fremgangsmåde til fremstilling af disse - Google Patents
O-carbamoyl-(D)-phenylalaniforbindelser og fremgangsmåde til fremstilling af disseInfo
- Publication number
- DK0815074T3 DK0815074T3 DK96901562T DK96901562T DK0815074T3 DK 0815074 T3 DK0815074 T3 DK 0815074T3 DK 96901562 T DK96901562 T DK 96901562T DK 96901562 T DK96901562 T DK 96901562T DK 0815074 T3 DK0815074 T3 DK 0815074T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenylalanium
- carbamoyl
- compounds
- preparation
- phenylalanium compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019950002543A KR0173862B1 (ko) | 1995-02-11 | 1995-02-11 | O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
| PCT/KR1996/000018 WO1996024577A1 (fr) | 1995-02-11 | 1996-02-08 | Composes de o-carbamyl-(d)-phenylalanilol et procede de preparation correspondant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0815074T3 true DK0815074T3 (da) | 2002-01-28 |
Family
ID=19408007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96901562T DK0815074T3 (da) | 1995-02-11 | 1996-02-08 | O-carbamoyl-(D)-phenylalaniforbindelser og fremgangsmåde til fremstilling af disse |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5705640C1 (fr) |
| EP (1) | EP0815074B1 (fr) |
| JP (1) | JP3828574B2 (fr) |
| KR (1) | KR0173862B1 (fr) |
| CN (1) | CN1070846C (fr) |
| CA (1) | CA2212326C (fr) |
| DE (1) | DE69615668T2 (fr) |
| DK (1) | DK0815074T3 (fr) |
| ES (1) | ES2165485T3 (fr) |
| PT (1) | PT815074E (fr) |
| WO (1) | WO1996024577A1 (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0173863B1 (ko) * | 1995-04-10 | 1999-04-01 | 조규향 | 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
| CA2240060C (fr) * | 1996-10-10 | 2007-07-17 | Sk Corporation | Composes de o-carbamoyl-phenylalaninol, sels de ces composes utiles sur le plan pharmaceutique, et procede de preparation de ces derniers |
| WO2006050037A1 (fr) * | 2004-10-28 | 2006-05-11 | Sk Corporation | Thérapie combinée pour la dépression |
| PL1890684T3 (pl) | 2005-06-08 | 2014-05-30 | Sk Biopharmaceuticals Co Ltd | Leczenie zaburzeń snu i czuwania |
| ATE459393T1 (de) * | 2005-06-22 | 2010-03-15 | Sk Holdings Co Ltd | Behandlung der sexuellen dysfunktion |
| CA2673487A1 (fr) * | 2006-10-13 | 2008-04-24 | Janssen Pharmaceutica Nv | Compositions de phenylalkylaminocarbamate |
| US8642772B2 (en) | 2008-10-14 | 2014-02-04 | Sk Biopharmaceuticals Co., Ltd. | Piperidine compounds, pharmaceutical composition comprising the same and its use |
| WO2011005473A2 (fr) | 2009-06-22 | 2011-01-13 | Shionogi Pharma, Inc. | Procédés de traitement ou de prévention de la fatigue |
| US8232315B2 (en) | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
| RU2557533C2 (ru) | 2009-11-06 | 2015-07-20 | Ск Биофармасъютиклс Ко., Лтд. | Способы лечения синдрома фибромиалгии |
| ES2447295T3 (es) | 2009-11-06 | 2014-03-11 | Sk Biopharmaceuticals Co., Ltd. | Métodos para el tratamiento del trastorno de déficit de atención/hiperactividad |
| US8623913B2 (en) | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
| US9610274B2 (en) | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| BR112015022197B1 (pt) | 2013-03-13 | 2022-06-07 | Sk Biopharmaceuticals Co., Ltd. | Uso de um composto para o tratamento de cataplexia |
| CN105873576B (zh) | 2013-07-18 | 2019-07-19 | 爵士制药国际Iii有限公司 | 治疗肥胖 |
| TWI655179B (zh) | 2014-02-28 | 2019-04-01 | 南韓商愛思開生物製藥股份有限公司 | 胺基羰基胺基甲酸酯化合物 |
| US10888542B2 (en) | 2014-02-28 | 2021-01-12 | Sk Biopharmaceuticals Co., Ltd. | Aminocarbonylcarbamate compounds |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| JP7219213B2 (ja) | 2016-09-06 | 2023-02-07 | ジャズ ファーマスティカルズ アイルランド リミテッド | (r)-2-アミノ-3-フェニルプロピルカルバメートの溶媒和物フォーム |
| SG11201903076QA (en) | 2016-10-06 | 2019-05-30 | Jazz Pharmaceuticals International Iii Ltd | Carbamoyl phenylalaninol compounds and uses therof |
| KR20240162165A (ko) | 2017-06-02 | 2024-11-14 | 재즈 파마슈티칼즈 아일랜드 리미티드 | 과다 졸림증을 치료하기 위한 방법 및 조성물 |
| RU2020108634A (ru) | 2017-07-31 | 2021-09-02 | Джаз Фармасьютикалз Айрлэнд Лимитед | Аналоги карбамоилфенилаланинола и способы их применения |
| CN110655500B (zh) * | 2018-06-28 | 2020-12-08 | 浙江京新药业股份有限公司 | 氨基甲酸酯衍生物及其制备方法和用途 |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
| KR102390194B1 (ko) | 2020-08-03 | 2022-04-25 | 셀라이온바이오메드 주식회사 | 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물 |
| KR20240101826A (ko) * | 2021-11-16 | 2024-07-02 | 액섬 몰타 엘티디. | 인지 장애를 치료하기 위한 방법 및 조성물 |
| WO2024249560A1 (fr) | 2023-05-30 | 2024-12-05 | Axsome Therapeutics, Inc. | Solriamfétol pour le traitement d'une déficience cognitive chez un sujet ayant une cognition altérée associée à une apnée obstructive du sommeil et une somnolence diurne excessive |
| WO2025006965A1 (fr) | 2023-06-29 | 2025-01-02 | Axsome Therapeutics, Inc. | Procédés d'administration de solriamfétol à des femmes en lactation |
| WO2025042959A1 (fr) | 2023-08-21 | 2025-02-27 | Axsome Therapeutics, Inc. | Utilisation de solriamfétol pour le traitement de maladies orphelines |
| WO2025165760A1 (fr) | 2024-01-29 | 2025-08-07 | Axsome Therapeutics, Inc. | Phénylalkylamino-carbamates destinés à être utilisés dans le traitement du trouble déficit de l'attention/hyperactivité |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1470277A1 (de) * | 1963-04-18 | 1969-05-29 | Siegfried Ag | Verfahren zur Herstellung von spasmolytische und tremolytische Eigenschaften aufweisenden Carbaminaten |
| FR8411M (fr) * | 1968-12-31 | 1971-03-31 | ||
| AT387572B (de) * | 1983-05-20 | 1989-02-10 | Ferrosan Ab | Verfahren zur herstellung von neuen 4-(4,4-bis-(p-fluorphenyl)-butyl)-1-carbophenox -piperazinen und von 1-piperazincarboxamiden |
| KR100197892B1 (ko) * | 1994-09-09 | 1999-06-15 | 남창우 | 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법 |
-
1995
- 1995-02-11 KR KR1019950002543A patent/KR0173862B1/ko not_active Expired - Lifetime
-
1996
- 1996-02-05 US US08596496 patent/US5705640C1/en not_active Expired - Lifetime
- 1996-02-08 PT PT96901562T patent/PT815074E/pt unknown
- 1996-02-08 JP JP52415596A patent/JP3828574B2/ja not_active Expired - Lifetime
- 1996-02-08 CA CA002212326A patent/CA2212326C/fr not_active Expired - Lifetime
- 1996-02-08 DK DK96901562T patent/DK0815074T3/da active
- 1996-02-08 ES ES96901562T patent/ES2165485T3/es not_active Expired - Lifetime
- 1996-02-08 EP EP96901562A patent/EP0815074B1/fr not_active Expired - Lifetime
- 1996-02-08 DE DE69615668T patent/DE69615668T2/de not_active Expired - Lifetime
- 1996-02-08 CN CN96191875A patent/CN1070846C/zh not_active Expired - Lifetime
- 1996-02-08 WO PCT/KR1996/000018 patent/WO1996024577A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP3828574B2 (ja) | 2006-10-04 |
| CN1070846C (zh) | 2001-09-12 |
| WO1996024577A1 (fr) | 1996-08-15 |
| CA2212326A1 (fr) | 1996-08-15 |
| EP0815074B1 (fr) | 2001-10-04 |
| PT815074E (pt) | 2002-03-28 |
| US5705640A (en) | 1998-01-06 |
| CA2212326C (fr) | 2008-12-23 |
| JPH11501617A (ja) | 1999-02-09 |
| EP0815074A1 (fr) | 1998-01-07 |
| US5705640C1 (en) | 2001-03-20 |
| CN1173863A (zh) | 1998-02-18 |
| DE69615668T2 (de) | 2002-07-11 |
| ES2165485T3 (es) | 2002-03-16 |
| KR960031427A (ko) | 1996-09-17 |
| KR0173862B1 (ko) | 1999-04-01 |
| DE69615668D1 (de) | 2001-11-08 |
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