DK0888110T3 - Mikropartikler af en kompositgel som bærere for aktive midler - Google Patents
Mikropartikler af en kompositgel som bærere for aktive midlerInfo
- Publication number
- DK0888110T3 DK0888110T3 DK97914410T DK97914410T DK0888110T3 DK 0888110 T3 DK0888110 T3 DK 0888110T3 DK 97914410 T DK97914410 T DK 97914410T DK 97914410 T DK97914410 T DK 97914410T DK 0888110 T3 DK0888110 T3 DK 0888110T3
- Authority
- DK
- Denmark
- Prior art keywords
- microparticles
- active principle
- composite gel
- controllable
- carriers
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 3
- 239000002131 composite material Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 239000000969 carrier Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 3
- 125000003440 L-leucyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C(C([H])([H])[H])([H])C([H])([H])[H] 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 235000019864 coconut oil Nutrition 0.000 abstract 1
- 239000003240 coconut oil Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/788—Of specified organic or carbon-based composition
- Y10S977/795—Composed of biological material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Colloid Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9603546A FR2746035B1 (fr) | 1996-03-15 | 1996-03-15 | Microparticules de gel composite susceptibles d'etre utilisees comme vecteur(s) de principe(s) actif(s), l'un de leurs procedes de preparation et leurs applications |
| PCT/FR1997/000471 WO1997034584A1 (fr) | 1996-03-15 | 1997-03-14 | Microparticules de gel composite comme vecteurs de principes actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0888110T3 true DK0888110T3 (da) | 2002-02-04 |
Family
ID=9490410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97914410T DK0888110T3 (da) | 1996-03-15 | 1997-03-14 | Mikropartikler af en kompositgel som bærere for aktive midler |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6180141B1 (da) |
| EP (1) | EP0888110B1 (da) |
| JP (1) | JP2000507934A (da) |
| AT (1) | ATE206912T1 (da) |
| AU (1) | AU2166097A (da) |
| CA (1) | CA2249274A1 (da) |
| DE (1) | DE69707433T2 (da) |
| DK (1) | DK0888110T3 (da) |
| ES (1) | ES2167727T3 (da) |
| FR (1) | FR2746035B1 (da) |
| PT (1) | PT888110E (da) |
| WO (1) | WO1997034584A1 (da) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6686446B2 (en) * | 1998-03-19 | 2004-02-03 | The Regents Of The University Of California | Methods and compositions for controlled polypeptide synthesis |
| FR2786098B1 (fr) * | 1998-11-20 | 2003-05-30 | Flamel Tech Sa | Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication |
| FR2801226B1 (fr) * | 1999-11-23 | 2002-01-25 | Flamel Tech Sa | Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation |
| CA2304906A1 (en) * | 2000-04-07 | 2001-10-07 | 1411198 Ontario Limited | 13-hode, a regulator of vascular biocompatibility and an inhibitor of cell hyperplasia |
| FR2814952B1 (fr) * | 2000-10-06 | 2004-01-02 | Flamel Tech Sa | Suspension colloidale de particules submicromiques de vectorisation de principes actifs et leur mode de preparation |
| FR2814951B1 (fr) * | 2000-10-06 | 2003-01-17 | Flamel Tech Sa | Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation |
| FR2822834B1 (fr) | 2001-04-02 | 2005-02-25 | Flamel Tech Sa | Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation |
| EP1379287A1 (en) * | 2001-04-12 | 2004-01-14 | Therics, Inc. | Method and apparatus for engineered regenerative biostructures |
| FR2823441B1 (fr) * | 2001-04-12 | 2004-09-10 | Thea Lab | Composition pharmaceutique a base de macrolides pour application locale en ophtalmologie et son procede de preparation |
| US20040126900A1 (en) * | 2001-04-13 | 2004-07-01 | Barry Stephen E | High affinity peptide- containing nanoparticles |
| FR2830447B1 (fr) * | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
| IL164222A0 (en) | 2002-04-09 | 2005-12-18 | Flamel Tech Sa | Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s) |
| DE60323474D1 (de) | 2002-04-09 | 2008-10-23 | Flamel Tech Sa | Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin |
| FR2840614B1 (fr) | 2002-06-07 | 2004-08-27 | Flamel Tech Sa | Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques |
| FR2843117B1 (fr) | 2002-07-30 | 2004-10-15 | Flamel Tech Sa | Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques |
| US7445796B2 (en) * | 2002-08-19 | 2008-11-04 | L. Perrigo Company | Pharmaceutically active particles of a monomodal particle size distribution and method |
| FR2855521B1 (fr) * | 2003-05-28 | 2005-08-05 | Flamel Tech Sa | Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques. |
| FR2860516B1 (fr) | 2003-10-03 | 2006-01-13 | Flamel Tech Sa | Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques |
| FR2862536B1 (fr) | 2003-11-21 | 2007-11-23 | Flamel Tech Sa | Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques |
| FR2868704B1 (fr) * | 2004-04-07 | 2007-09-14 | Ethypharm Sa | Utilisation de lipides pour ameliorer la biodisponibilite de principes actifs proteiques en formulations injectables sous cutanees ou intra-musculaires |
| CN103223160B (zh) | 2004-07-19 | 2015-02-18 | 比奥孔有限公司 | 胰岛素-低聚物共轭物,制剂及其用途 |
| FR2873040B1 (fr) * | 2004-07-19 | 2007-11-30 | Flamel Technologies Sa | Formulation colloidale d'insuline longue action et sa preparation |
| US20060224095A1 (en) * | 2005-04-05 | 2006-10-05 | University Of New Hampshire | Biocompatible polymeric vesicles self assembled from triblock copolymers |
| US9505867B2 (en) | 2005-05-31 | 2016-11-29 | Ecole Polytechmique Fédérale De Lausanne | Triblock copolymers for cytoplasmic delivery of gene-based drugs |
| FR2910318B1 (fr) * | 2006-12-20 | 2009-07-03 | Flamel Technologies Sa | Dispersion de polyaminoacides dans une phase lipidique continue. |
| FR2914188B1 (fr) * | 2007-03-28 | 2012-06-22 | Trophos | Nouvelle composition a base d'oxime de cholest-4-en-3-one |
| JP5814793B2 (ja) | 2008-11-25 | 2015-11-17 | エコール ポリテクニク フェデラル ド ローザンヌ（エーペーエフエル） | ブロックコポリマーおよびその使用 |
| US9060927B2 (en) * | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
| EP2555614B1 (en) | 2010-04-06 | 2018-11-14 | Agrosavfe N.V. | Specific delivery of agrochemicals |
| US20130224226A1 (en) | 2010-08-26 | 2013-08-29 | Agrosavfe N.V. | Insect binding antibodies |
| ES2634547T3 (es) | 2010-08-26 | 2017-09-28 | Agrosavfe N.V. | Composiciones para el tratamiento de semillas |
| US10226417B2 (en) * | 2011-09-16 | 2019-03-12 | Peter Jarrett | Drug delivery systems and applications |
| WO2013050594A1 (en) | 2011-10-06 | 2013-04-11 | Agrosavfe N.V. | Manufacturing of specifically targeting microcapsules |
| ITMI20111866A1 (it) | 2011-10-13 | 2013-04-14 | Bio Ker S R L | Polietilenglicoli modificati e loro complessi supramolecolari con macromolecole biologicamente attive |
| US10711106B2 (en) | 2013-07-25 | 2020-07-14 | The University Of Chicago | High aspect ratio nanofibril materials |
| US20170223964A1 (en) | 2014-04-17 | 2017-08-10 | Basf Se | Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides |
| US9968092B2 (en) | 2014-04-17 | 2018-05-15 | Basf Se | Combination of novel nitrification inhibitors and biopesticides as well as combination of (thio)phosphoric acid triamides and biopesticides |
| AU2016214305B2 (en) | 2015-02-06 | 2020-10-08 | Basf Se | Pyrazole compounds as nitrification inhibitors |
| BR112017024249A2 (pt) | 2015-05-12 | 2018-07-24 | Basf Se | ?utilização de um composto, composição, mistura agroquímica, métodos para a redução da nitrificação e para o tratamento de um fertilizante e composto de tioéter? |
| BR112018073298A2 (pt) | 2016-05-18 | 2019-02-19 | Basf Se | cápsula, suspensão de cápsula, mistura, uso das cápsulas e método para reduzir a nitrificação |
| EP3737235A1 (en) | 2018-01-09 | 2020-11-18 | Basf Se | Silylethynyl hetaryl compounds as nitrification inhibitors |
| CA3093781A1 (en) | 2018-02-28 | 2019-09-06 | Basf Se | Use of n-functionalized alkoxy pyrazole compounds as nitrification inhibitors |
| CN115568473A (zh) | 2018-02-28 | 2023-01-06 | 巴斯夫欧洲公司 | 烷氧基吡唑作为硝化抑制剂的用途 |
| WO2019166558A1 (en) | 2018-02-28 | 2019-09-06 | Basf Se | Use of pyrazole propargyl ethers as nitrification inhibitors |
| US12290068B2 (en) | 2018-05-27 | 2025-05-06 | The State Of Israel, Ministry Of Agriculture & Rural Development Agricultural Research Organization | Single cell encapsulation via pickering emulsion for bio-pesticides application |
| WO2020002472A1 (en) | 2018-06-28 | 2020-01-02 | Basf Se | Use of alkynylthiophenes as nitrification inhibitors |
| HUE067997T2 (hu) | 2018-07-23 | 2024-12-28 | Basf Se | Szubsztituált 2-tiazolinok mint nitrifikációs inhibitorok |
| CN112424147B (zh) | 2018-07-23 | 2023-06-30 | 巴斯夫欧洲公司 | 取代噻唑烷化合物作为硝化抑制剂的用途 |
| CA3206495A1 (en) | 2021-02-02 | 2022-08-11 | Alexander Wissemeier | Synergistic action of dcd and alkoxypyrazoles as nitrification inhibitors |
| CA3219022A1 (en) | 2021-05-21 | 2022-11-24 | Barbara Nave | Use of ethynylpyridine compounds as nitrification inhibitors |
| EP4341248A1 (en) | 2021-05-21 | 2024-03-27 | Basf Se | Use of an n-functionalized alkoxy pyrazole compound as nitrification inhibitor |
| BR112023027004A2 (pt) | 2021-06-21 | 2024-03-12 | Basf Se | Estrutura de metal-orgânica, uso da estrutura de metal-orgânica, composição para uso na redução da nitrificação, mistura agroquímica e métodos de redução da nitrificação, de tratamento de fertilizante ou composição de fertilizante e de preparação de uma estrutura de metal-orgânica |
| WO2023118418A1 (en) | 2021-12-23 | 2023-06-29 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | A novel glv-phenolamide: biosynthesis and function in protecting plants from herbivore attack |
| WO2023203066A1 (en) | 2022-04-21 | 2023-10-26 | Basf Se | Synergistic action as nitrification inhibitors of dcd oligomers with alkoxypyrazole and its oligomers |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8601100D0 (en) * | 1986-01-17 | 1986-02-19 | Cosmas Damian Ltd | Drug delivery system |
| US4976968A (en) * | 1989-02-24 | 1990-12-11 | Clinical Technologies Associates, Inc. | Anhydrous delivery systems for pharmacological agents |
| GB2260080A (en) * | 1991-10-04 | 1993-04-07 | Rhone Poulenc Rorer Ltd | Gelled alginate compositions |
| FR2732218B1 (fr) * | 1995-03-28 | 1997-08-01 | Flamel Tech Sa | Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s) et leurs procedes de preparation |
-
1996
- 1996-03-15 FR FR9603546A patent/FR2746035B1/fr not_active Expired - Fee Related
-
1997
- 1997-03-14 DK DK97914410T patent/DK0888110T3/da active
- 1997-03-14 AT AT97914410T patent/ATE206912T1/de not_active IP Right Cessation
- 1997-03-14 ES ES97914410T patent/ES2167727T3/es not_active Expired - Lifetime
- 1997-03-14 PT PT97914410T patent/PT888110E/pt unknown
- 1997-03-14 JP JP9533198A patent/JP2000507934A/ja not_active Ceased
- 1997-03-14 EP EP97914410A patent/EP0888110B1/fr not_active Expired - Lifetime
- 1997-03-14 CA CA002249274A patent/CA2249274A1/en not_active Abandoned
- 1997-03-14 DE DE69707433T patent/DE69707433T2/de not_active Expired - Fee Related
- 1997-03-14 US US09/147,032 patent/US6180141B1/en not_active Expired - Fee Related
- 1997-03-14 AU AU21660/97A patent/AU2166097A/en not_active Abandoned
- 1997-03-14 WO PCT/FR1997/000471 patent/WO1997034584A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2167727T3 (es) | 2002-05-16 |
| JP2000507934A (ja) | 2000-06-27 |
| DE69707433T2 (de) | 2002-06-06 |
| EP0888110B1 (fr) | 2001-10-17 |
| US6180141B1 (en) | 2001-01-30 |
| CA2249274A1 (en) | 1997-09-25 |
| WO1997034584A1 (fr) | 1997-09-25 |
| EP0888110A1 (fr) | 1999-01-07 |
| DE69707433D1 (de) | 2001-11-22 |
| ATE206912T1 (de) | 2001-11-15 |
| FR2746035B1 (fr) | 1998-06-12 |
| PT888110E (pt) | 2002-04-29 |
| FR2746035A1 (fr) | 1997-09-19 |
| AU2166097A (en) | 1997-10-10 |
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