DK0883610T3 - Fremgangsmåde til fremstilling af 1,4,7,10-tetraazacyclododecan og derivater heraf - Google Patents
Fremgangsmåde til fremstilling af 1,4,7,10-tetraazacyclododecan og derivater herafInfo
- Publication number
- DK0883610T3 DK0883610T3 DK96946361T DK96946361T DK0883610T3 DK 0883610 T3 DK0883610 T3 DK 0883610T3 DK 96946361 T DK96946361 T DK 96946361T DK 96946361 T DK96946361 T DK 96946361T DK 0883610 T3 DK0883610 T3 DK 0883610T3
- Authority
- DK
- Denmark
- Prior art keywords
- tetraazacyclododecane
- derivatives
- preparation
- cyclotetramerization
- benzylaziridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19608307A DE19608307C1 (de) | 1996-02-26 | 1996-02-26 | Verfahren zur Herstellung von 1,4,7,10-Tetraazacyclododecan und dessen Derivaten |
| PCT/EP1997/000927 WO1997031905A1 (de) | 1996-02-26 | 1997-02-26 | Verfahren zur herstellung von 1,4,7,10-tetraazacyclododecan und dessen derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0883610T3 true DK0883610T3 (da) | 2000-09-25 |
Family
ID=7787168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96946361T DK0883610T3 (da) | 1996-02-26 | 1997-02-26 | Fremgangsmåde til fremstilling af 1,4,7,10-tetraazacyclododecan og derivater heraf |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0883610B1 (da) |
| JP (2) | JP4745469B2 (da) |
| KR (1) | KR100453668B1 (da) |
| CN (1) | CN1081186C (da) |
| AT (1) | ATE194602T1 (da) |
| AU (1) | AU717720B2 (da) |
| CA (1) | CA2247265C (da) |
| CZ (1) | CZ290128B6 (da) |
| DE (2) | DE19608307C1 (da) |
| DK (1) | DK0883610T3 (da) |
| ES (1) | ES2148837T3 (da) |
| GR (1) | GR3034468T3 (da) |
| IL (1) | IL125419A (da) |
| NO (1) | NO310870B1 (da) |
| NZ (1) | NZ331520A (da) |
| PL (1) | PL185927B1 (da) |
| PT (1) | PT883610E (da) |
| SK (1) | SK281972B6 (da) |
| WO (1) | WO1997031905A1 (da) |
| ZA (1) | ZA971672B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19608307C1 (de) * | 1996-02-26 | 1997-08-28 | Schering Ag | Verfahren zur Herstellung von 1,4,7,10-Tetraazacyclododecan und dessen Derivaten |
| CZ2005653A3 (cs) * | 2005-10-17 | 2007-01-10 | Azacycles S. R. O. | Způsob přípravy 1,4,7,10-tetraazacyklododekanua jeho N-acylderivátů |
| DE102009057274B4 (de) | 2009-12-02 | 2011-09-01 | Bayer Schering Pharma Aktiengesellschaft | Gadobutrolherstellung mittels Trioxobicyclo-octan |
| DE102010013833A1 (de) | 2010-03-29 | 2011-09-29 | Bayer Schering Pharma Aktiengesellschaft | Herstellung von Gadobutrol mittels Dimethylformamiddimethylacetal |
| CN101845112B (zh) * | 2010-06-02 | 2011-09-14 | 华东理工大学 | 一种基于高分子纳米粒子的高灵敏性核磁共振成像造影剂的制备方法 |
| DE102010023105A1 (de) | 2010-06-04 | 2011-12-08 | Bayer Schering Pharma Aktiengesellschaft | Gadobutrolherstellung im Eintopfverfahren mittels DMF-acetal und N-Methylimidazol |
| WO2012143355A1 (en) | 2011-04-21 | 2012-10-26 | Bayer Intellectual Property Gmbh | Preparation of high-purity gadobutrol |
| KR102067551B1 (ko) * | 2018-04-12 | 2020-01-17 | (주) 에프엔지리서치 | 오염토양 또는 오염수질 복원용 화합물 |
| CN108794417A (zh) * | 2018-08-04 | 2018-11-13 | 许昌恒生制药有限公司 | 一种医疗诊断造影剂中间体的制备方法 |
| EP4335461A1 (en) | 2022-09-09 | 2024-03-13 | Bayer AG | Combinations of contrast agents |
| EP4335840A1 (en) | 2022-09-09 | 2024-03-13 | Bayer Aktiengesellschaft | New contrast agents for use in diagnostic imaging |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3828023A (en) * | 1971-09-13 | 1974-08-06 | Dow Chemical Co | Process for preparing cyclic oligomers of n-substituted aziridines |
| US6693190B1 (en) * | 1994-05-11 | 2004-02-17 | Bracco International B.V. | Enhanced relaxivity monomeric and multimeric compounds |
| US6048979A (en) * | 1995-03-10 | 2000-04-11 | Nycomed Salutar, Inc. | Preparation of N-arylmethyl aziridine derivatives, 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom and N-arylmethyl-ethanol-amine sulphonate esters as intermediates |
| DE19608307C1 (de) * | 1996-02-26 | 1997-08-28 | Schering Ag | Verfahren zur Herstellung von 1,4,7,10-Tetraazacyclododecan und dessen Derivaten |
-
1996
- 1996-02-26 DE DE19608307A patent/DE19608307C1/de not_active Expired - Fee Related
-
1997
- 1997-02-26 AT AT96946361T patent/ATE194602T1/de active
- 1997-02-26 EP EP96946361A patent/EP0883610B1/de not_active Expired - Lifetime
- 1997-02-26 NZ NZ331520A patent/NZ331520A/xx not_active IP Right Cessation
- 1997-02-26 KR KR10-1998-0706649A patent/KR100453668B1/ko not_active Expired - Lifetime
- 1997-02-26 ZA ZA9701672A patent/ZA971672B/xx unknown
- 1997-02-26 ES ES96946361T patent/ES2148837T3/es not_active Expired - Lifetime
- 1997-02-26 CZ CZ19982721A patent/CZ290128B6/cs not_active IP Right Cessation
- 1997-02-26 CN CN97192459A patent/CN1081186C/zh not_active Expired - Lifetime
- 1997-02-26 SK SK1172-98A patent/SK281972B6/sk not_active IP Right Cessation
- 1997-02-26 PT PT96946361T patent/PT883610E/pt unknown
- 1997-02-26 DK DK96946361T patent/DK0883610T3/da active
- 1997-02-26 IL IL12541997A patent/IL125419A/xx not_active IP Right Cessation
- 1997-02-26 CA CA002247265A patent/CA2247265C/en not_active Expired - Lifetime
- 1997-02-26 DE DE59702009T patent/DE59702009D1/de not_active Expired - Lifetime
- 1997-02-26 AU AU18772/97A patent/AU717720B2/en not_active Expired
- 1997-02-26 JP JP53059297A patent/JP4745469B2/ja not_active Expired - Lifetime
- 1997-02-26 WO PCT/EP1997/000927 patent/WO1997031905A1/de not_active Ceased
- 1997-02-26 PL PL97328468A patent/PL185927B1/pl unknown
-
1998
- 1998-08-25 NO NO19983901A patent/NO310870B1/no not_active IP Right Cessation
-
2000
- 2000-09-21 GR GR20000402157T patent/GR3034468T3/el unknown
-
2009
- 2009-05-27 JP JP2009127490A patent/JP2009185077A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| SK117298A3 (en) | 1999-01-11 |
| CZ272198A3 (cs) | 2000-02-16 |
| EP0883610A1 (de) | 1998-12-16 |
| WO1997031905A1 (de) | 1997-09-04 |
| CA2247265C (en) | 2005-06-21 |
| CA2247265A1 (en) | 1997-09-04 |
| ATE194602T1 (de) | 2000-07-15 |
| DE59702009D1 (de) | 2000-08-17 |
| IL125419A0 (en) | 1999-03-12 |
| JP4745469B2 (ja) | 2011-08-10 |
| KR100453668B1 (ko) | 2004-12-16 |
| NO310870B1 (no) | 2001-09-10 |
| PL328468A1 (en) | 1999-02-01 |
| SK281972B6 (sk) | 2001-09-11 |
| JP2009185077A (ja) | 2009-08-20 |
| PL185927B1 (pl) | 2003-09-30 |
| AU1877297A (en) | 1997-09-16 |
| CN1211975A (zh) | 1999-03-24 |
| GR3034468T3 (en) | 2000-12-29 |
| IL125419A (en) | 2001-01-11 |
| ES2148837T3 (es) | 2000-10-16 |
| PT883610E (pt) | 2000-10-31 |
| KR19990087248A (ko) | 1999-12-15 |
| DE19608307C1 (de) | 1997-08-28 |
| HK1018618A1 (en) | 1999-12-30 |
| CN1081186C (zh) | 2002-03-20 |
| ZA971672B (en) | 1997-08-29 |
| JP2000505467A (ja) | 2000-05-09 |
| EP0883610B1 (de) | 2000-07-12 |
| NO983901D0 (no) | 1998-08-25 |
| AU717720B2 (en) | 2000-03-30 |
| NO983901L (no) | 1998-08-25 |
| CZ290128B6 (cs) | 2002-06-12 |
| NZ331520A (en) | 2000-01-28 |
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