DK0882033T3 - Benzofuran-acrylsyrederivater og deres anvendelse som modulatorer for RXRS- eller RARS-receptorer - Google Patents

Benzofuran-acrylsyrederivater og deres anvendelse som modulatorer for RXRS- eller RARS-receptorer

Info

Publication number: DK0882033T3
Authority: DK; Denmark
Prior art keywords: pct; rxrs; rars; benzofuran; modulators
Prior art date: 1996-12-04

Application number

DK97950223T

Other languages

English (en)

Inventor

Philippe Diaz

Bruno Charpentier

Original Assignee

Galderma Rech Dermatologique

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-04

Filing date

1997-12-04

Publication date

2001-10-22

1997-12-04 Application filed by Galderma Rech Dermatologique filed Critical Galderma Rech Dermatologique

2001-10-22 Application granted granted Critical

2001-10-22 Publication of DK0882033T3 publication Critical patent/DK0882033T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Gerontology & Geriatric Medicine (AREA)
Birds (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Furan Compounds (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK97950223T 1996-12-04 1997-12-04 Benzofuran-acrylsyrederivater og deres anvendelse som modulatorer for RXRS- eller RARS-receptorer DK0882033T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9614882A FR2756561B1 (fr)	1996-12-04	1996-12-04	Composes heteroaryles, compositions pharmaceutiques et cosmetiques les contenant et utilisations
PCT/FR1997/002205 WO1998024778A1 (fr)	1996-12-04	1997-12-04	Derives d'acides benzofuranne-acryliques et leur utilisation comme modulateurs des recepteurs rxrs ou rars

Publications (1)

Publication Number	Publication Date
DK0882033T3 true DK0882033T3 (da)	2001-10-22

Family

ID=9498327

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97950223T DK0882033T3 (da)	1996-12-04	1997-12-04	Benzofuran-acrylsyrederivater og deres anvendelse som modulatorer for RXRS- eller RARS-receptorer

Country Status (16)

Country	Link
US (1)	US6030952A (da)
EP (1)	EP0882033B1 (da)
JP (1)	JP3253637B2 (da)
AT (1)	ATE204270T1 (da)
AU (1)	AU710955B2 (da)
BR (1)	BR9708297A (da)
CA (1)	CA2245250C (da)
DE (1)	DE69706142T2 (da)
DK (1)	DK0882033T3 (da)
ES (1)	ES2163805T3 (da)
FR (1)	FR2756561B1 (da)
GR (1)	GR3036408T3 (da)
MX (1)	MX9806188A (da)
NZ (1)	NZ330971A (da)
PT (1)	PT882033E (da)
WO (1)	WO1998024778A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2779723B1 (fr) *	1998-06-12	2000-07-13	Cird Galderma	Composes biaryles heterocycliques aromatiques, compositions pharmaceutiques et cosmetiques les contenant et utilisations
JP4780429B2 (ja) *	2000-04-07	2011-09-28	大正製薬株式会社	ミノキシジル含有製剤
US20030157046A1 (en) *	2000-04-07	2003-08-21	Koji Imamura	Minoxidil-containing preparations
CA2417500C (en) *	2000-07-28	2008-11-18	Georgetown University Medical Center	Erbb-2 selective small molecule kinase inhibitors
AU2002333655A1 (en) *	2001-09-25	2003-04-07	Smithkline Beecham Corporation	Bicyclic heterocycles as rxr ligands
FR2910321B1 (fr)	2006-12-21	2009-07-10	Galderma Res & Dev S N C Snc	Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr)	2006-12-21	2009-02-13	Galderma Res & Dev S N C Snc	Emulsion comprenant au moins un retinoide et du peroxyde de benzole
US9079854B2 (en)	2007-07-13	2015-07-14	The Cleveland Clinic Foundation	Hydrazone modulators of cannabinoid receptors
US9394267B2 (en)	2007-07-13	2016-07-19	The Cleveland Clinic Foundation	Heterocyclic modulators of cannabinoid receptors
US8309595B2 (en)	2007-07-13	2012-11-13	Board Of Regents, The University Of Texas System	Hydrazone modulators of cannabinoid receptors
US8440832B2 (en)	2007-07-13	2013-05-14	Board Of Regents, The University Of Texas System	Heterocyclic modulators of cannabinoid receptors
FR2931661B1 (fr)	2008-05-30	2010-07-30	Galderma Res & Dev	Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
CN104936596A (zh)	2012-07-13	2015-09-23	克利夫兰临床基金会	神经保护性cb2受体激动剂

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4326055A (en) *	1977-12-22	1982-04-20	Hoffmann-La Roche Inc.	Stilbene derivatives
GB2042562B (en)	1979-02-05	1983-05-11	Sandoz Ltd	Stabilising polymers
CA2093577C (en) *	1992-05-07	2006-01-03	Michael Klaus	Alkyl or alkoxy substituted s-heterocyclic retinoids
NL9300801A (nl)	1992-05-22	1993-12-16	Ciba Geigy	3-(acyloxyfenyl)benzofuran-2-on als stabilisatoren.
US5977125A (en) *	1994-10-31	1999-11-02	Eisai Co., Ltd.	Mono-or polyenic carboxylic acid derivatives
FR2744452B1 (fr) *	1996-02-06	1998-03-06	Cird Galderma	Composes biaryles heterocycliques, compositions pharmaceutiques et cosmetiques les contenant et utilisations

1996
- 1996-12-04 FR FR9614882A patent/FR2756561B1/fr not_active Expired - Fee Related
1997
- 1997-12-04 NZ NZ330971A patent/NZ330971A/en unknown
- 1997-12-04 US US09/117,696 patent/US6030952A/en not_active Expired - Fee Related
- 1997-12-04 DE DE69706142T patent/DE69706142T2/de not_active Expired - Fee Related
- 1997-12-04 WO PCT/FR1997/002205 patent/WO1998024778A1/fr not_active Ceased
- 1997-12-04 PT PT97950223T patent/PT882033E/pt unknown
- 1997-12-04 EP EP97950223A patent/EP0882033B1/fr not_active Expired - Lifetime
- 1997-12-04 DK DK97950223T patent/DK0882033T3/da active
- 1997-12-04 JP JP52529098A patent/JP3253637B2/ja not_active Expired - Fee Related
- 1997-12-04 AU AU53260/98A patent/AU710955B2/en not_active Ceased
- 1997-12-04 CA CA002245250A patent/CA2245250C/fr not_active Expired - Fee Related
- 1997-12-04 AT AT97950223T patent/ATE204270T1/de not_active IP Right Cessation
- 1997-12-04 BR BR9708297A patent/BR9708297A/pt not_active IP Right Cessation
- 1997-12-04 ES ES97950223T patent/ES2163805T3/es not_active Expired - Lifetime
1998
- 1998-07-31 MX MX9806188A patent/MX9806188A/es not_active IP Right Cessation
2001
- 2001-08-17 GR GR20010401135T patent/GR3036408T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE204270T1 (de)	2001-09-15
DE69706142D1 (de)	2001-09-20
NZ330971A (en)	2000-02-28
FR2756561B1 (fr)	1999-01-08
EP0882033B1 (fr)	2001-08-16
US6030952A (en)	2000-02-29
FR2756561A1 (fr)	1998-06-05
EP0882033A1 (fr)	1998-12-09
AU5326098A (en)	1998-06-29
CA2245250A1 (fr)	1998-06-11
PT882033E (pt)	2002-01-30
JP3253637B2 (ja)	2002-02-04
JPH11504052A (ja)	1999-04-06
WO1998024778A1 (fr)	1998-06-11
CA2245250C (fr)	2003-07-22
MX9806188A (es)	1998-10-31
GR3036408T3 (en)	2001-11-30
ES2163805T3 (es)	2002-02-01
DE69706142T2 (de)	2001-11-22
BR9708297A (pt)	1999-08-03
AU710955B2 (en)	1999-09-30

Publication	Publication Date	Title
MX9605940A (es)	1998-04-30	Compuestos bioaromaticos que llevan un grupo adamantilo en orto, composiciones farmaceuticas y cosmeticas que los contienen y utilizaciones.
DK0832081T3 (da)	2003-05-26	Bicykliske-aromatiske forbindelser
DK0882033T3 (da)	2001-10-22	Benzofuran-acrylsyrederivater og deres anvendelse som modulatorer for RXRS- eller RARS-receptorer
BR9702074A (pt)	1998-05-26	Compostos biaril heterocíclicos composições farmacêuticas e cosméticas que os contêm e suas utilizações
ES2158597T3 (es)	2001-09-01	Compuestos bioaromaticos, composiciones farmaceuticas y cosmeticas que los contienen y utilizaciones.
MX9501849A (es)	1997-02-28	Nuevos compuestos biciclicos-aromaticos, composiciones farmaceuticas y cosmeticas que los contienen y sus usos.
AR005860A1 (es)	1999-07-21	Compuestos heterociclicos aromaticos, composiciones farmaceuticas y cosmeticas que los contienen, y su utilización.
DK0661260T3 (da)	1997-07-28	Hidtil ukendte biaromatiske forbindelser afledt af amider, farmaceutiske og kosmetiske præparater,der indeholder dem, og deres anvendelser
FR2713640B1 (fr)	1996-01-05	Nouveaux composés aromatiques polycycliques, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
ATE198467T1 (de)	2001-01-15	Diaromatische propynyl- oder dienylverbindungen
NO20006337L (no)	2001-02-12	Diarylselenidforbindelser og deres anvendelse i human- eller veterinærmedisin og i kosmetikk
BR9706891A (pt)	2000-01-25	Composto, medicamento, composição farmacêutica e composição cosmética.
NO995838L (no)	2000-01-31	Nye heteroetynylenforbindelser og farmasoeytiske og kosmetiske preparater inneholdende de samme
MX9605916A (es)	1998-05-31	Compuestos bioaromaticos que llevan un grupo adamantilo en para, composiciones farmaceuticos y cosmeticas que los contienen y utilizaciones.
MX9710466A (es)	1998-09-30	Compuestos de estilbeno que contienen un grupo adamantilo, composiciones que los contienen y sus usos.