DK0854873T3 - Galathanminderivater og fremgangsmåde til deres fremstilling - Google Patents
Galathanminderivater og fremgangsmåde til deres fremstillingInfo
- Publication number
- DK0854873T3 DK0854873T3 DK96931169T DK96931169T DK0854873T3 DK 0854873 T3 DK0854873 T3 DK 0854873T3 DK 96931169 T DK96931169 T DK 96931169T DK 96931169 T DK96931169 T DK 96931169T DK 0854873 T3 DK0854873 T3 DK 0854873T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- hydrogen
- galatine
- miner
- derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000007243 oxidative cyclization reaction Methods 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9519267.0A GB9519267D0 (en) | 1995-09-21 | 1995-09-21 | Preparation of alkaloids |
| PCT/GB1996/002334 WO1997011077A1 (en) | 1995-09-21 | 1996-09-23 | Galanthamine derivatives and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0854873T3 true DK0854873T3 (da) | 2002-07-01 |
Family
ID=10781038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96931169T DK0854873T3 (da) | 1995-09-21 | 1996-09-23 | Galathanminderivater og fremgangsmåde til deres fremstilling |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6093815A (da) |
| EP (1) | EP0854873B1 (da) |
| AT (1) | ATE214070T1 (da) |
| AU (1) | AU714711B2 (da) |
| CA (1) | CA2230826C (da) |
| CY (1) | CY2301B1 (da) |
| DE (1) | DE69619685T2 (da) |
| DK (1) | DK0854873T3 (da) |
| ES (1) | ES2173316T3 (da) |
| GB (1) | GB9519267D0 (da) |
| PT (1) | PT854873E (da) |
| WO (1) | WO1997011077A1 (da) |
| ZA (1) | ZA968028B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1163224C (zh) | 1998-09-30 | 2004-08-25 | 武田药品工业株式会社 | 改善膀胱排泄能力的药物 |
| JP2003136077A (ja) * | 2001-10-31 | 2003-05-13 | Nec Corp | 半導体製造に用いる洗浄水又は浸漬水の製造装置 |
| WO2005065662A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Solid dosage formulations of galantamine |
| US20050191349A1 (en) * | 2003-12-31 | 2005-09-01 | Garth Boehm | Galantamine formulations |
| DE602006016441D1 (de) * | 2005-05-13 | 2010-10-07 | Alza Corp | Mehrlagiges arzneimittelausbringsystem mit sperre gegen reservoirmaterialfluss |
| EP1937226A2 (en) * | 2005-09-23 | 2008-07-02 | Alza Corporation | Transdermal galantamine delivery system |
| AT504663B1 (de) * | 2007-02-22 | 2008-07-15 | Sanochemia Pharmazeutika Ag | Verfahren zum herstellen von hochreinen 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- f)(2) benzazepinen sowie dessen derivaten |
| EP2009015B1 (en) * | 2007-06-18 | 2012-01-11 | Aurobindo Pharma Limited | Process for the preparation of galantamine hydrobromide |
| AT507039A1 (de) | 2008-06-26 | 2010-01-15 | Sanochemia Pharmazeutika Ag | Verfahren zum herstellen von hochreinen benzazepinderivaten |
| CN106977412B (zh) * | 2017-05-15 | 2019-08-02 | 张家港威胜生物医药有限公司 | 一种加兰他敏关键中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0363415B1 (en) * | 1987-05-04 | 2008-10-15 | Davis, Bonnie | Compounds for the treatment of alzheimer's disease |
| SI0787115T1 (en) * | 1994-10-21 | 2000-04-30 | Sanochemia Pharmazeutika Ag | PROCESS FOR PRODUCING DERIVATIVES OF 4a,5,9,10,11,12,-HEXAHYDRO-6H-BENZOFURO(3a,3,2-ef)(2)BENZAZEPINE |
| AT401058B (de) * | 1994-10-21 | 1996-06-25 | Waldheim Pharmazeutika Gmbh | Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins |
-
1995
- 1995-09-21 GB GBGB9519267.0A patent/GB9519267D0/en active Pending
-
1996
- 1996-09-23 AU AU69964/96A patent/AU714711B2/en not_active Expired
- 1996-09-23 DE DE69619685T patent/DE69619685T2/de not_active Expired - Lifetime
- 1996-09-23 CA CA002230826A patent/CA2230826C/en not_active Expired - Lifetime
- 1996-09-23 AT AT96931169T patent/ATE214070T1/de active
- 1996-09-23 US US09/043,330 patent/US6093815A/en not_active Expired - Lifetime
- 1996-09-23 WO PCT/GB1996/002334 patent/WO1997011077A1/en not_active Ceased
- 1996-09-23 PT PT96931169T patent/PT854873E/pt unknown
- 1996-09-23 DK DK96931169T patent/DK0854873T3/da active
- 1996-09-23 ES ES96931169T patent/ES2173316T3/es not_active Expired - Lifetime
- 1996-09-23 EP EP96931169A patent/EP0854873B1/en not_active Expired - Lifetime
- 1996-09-23 ZA ZA9608028A patent/ZA968028B/xx unknown
-
2002
- 2002-11-25 CY CY0200063A patent/CY2301B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2230826A1 (en) | 1997-03-27 |
| PT854873E (pt) | 2002-08-30 |
| CA2230826C (en) | 2008-09-02 |
| DE69619685T2 (de) | 2002-10-17 |
| ATE214070T1 (de) | 2002-03-15 |
| CY2301B1 (en) | 2003-07-04 |
| ZA968028B (en) | 1997-09-23 |
| WO1997011077A1 (en) | 1997-03-27 |
| DE69619685D1 (de) | 2002-04-11 |
| EP0854873A1 (en) | 1998-07-29 |
| US6093815A (en) | 2000-07-25 |
| AU6996496A (en) | 1997-04-09 |
| EP0854873B1 (en) | 2002-03-06 |
| ES2173316T3 (es) | 2002-10-16 |
| GB9519267D0 (en) | 1995-11-22 |
| AU714711B2 (en) | 2000-01-06 |
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