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DK0847390T3 - Fremgangsmåde til fremstilling af 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepin-5-carboxamid - Google Patents

Fremgangsmåde til fremstilling af 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepin-5-carboxamid

Info

Publication number
DK0847390T3
DK0847390T3 DK96900104T DK96900104T DK0847390T3 DK 0847390 T3 DK0847390 T3 DK 0847390T3 DK 96900104 T DK96900104 T DK 96900104T DK 96900104 T DK96900104 T DK 96900104T DK 0847390 T3 DK0847390 T3 DK 0847390T3
Authority
DK
Denmark
Prior art keywords
pct
dibenz
azepine
carboxamide
dihydro
Prior art date
Application number
DK96900104T
Other languages
Danish (da)
English (en)
Inventor
Alberto Milanese
Original Assignee
Four Plus One Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Four Plus One Ltd filed Critical Four Plus One Ltd
Application granted granted Critical
Publication of DK0847390T3 publication Critical patent/DK0847390T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK96900104T 1995-01-13 1996-01-03 Fremgangsmåde til fremstilling af 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepin-5-carboxamid DK0847390T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI950056A IT1272897B (it) 1995-01-13 1995-01-13 Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
PCT/EP1996/000004 WO1996021649A1 (fr) 1995-01-13 1996-01-03 PROCEDE DE PREPARATION DU 10-OXO-10,11-DIHYDRO-5H-DIBENZ(b,f)AZEPIN-5-CARBOXAMIDE

Publications (1)

Publication Number Publication Date
DK0847390T3 true DK0847390T3 (da) 2000-11-06

Family

ID=11370213

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96900104T DK0847390T3 (da) 1995-01-13 1996-01-03 Fremgangsmåde til fremstilling af 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepin-5-carboxamid

Country Status (11)

Country Link
US (1) US5808058A (fr)
EP (1) EP0847390B1 (fr)
AT (1) ATE195518T1 (fr)
AU (1) AU4347996A (fr)
DE (1) DE69609843T2 (fr)
DK (1) DK0847390T3 (fr)
ES (1) ES2150093T3 (fr)
GR (1) GR3034844T3 (fr)
IT (1) IT1272897B (fr)
PT (1) PT847390E (fr)
WO (1) WO1996021649A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408224B (de) * 1999-03-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von oxcarbazepin
GB0002740D0 (en) * 2000-02-07 2000-03-29 Novartis Ag Organic compounds
HUP0303154A3 (en) * 2001-02-12 2009-08-28 Teva Pharma New crystal forms of oxcarbazepine and processes for their preparation
GB0112812D0 (en) * 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
CA2407173C (fr) 2001-10-09 2009-09-29 Max India Limited Mode de preparation de la10-methoxycarbamazepine
EP1302464A1 (fr) * 2001-10-09 2003-04-16 Max India Limited Procédé pour la préparation de 10-méthoxycarbamazépine
US7091339B2 (en) 2002-06-14 2006-08-15 Taro Pharmaceuticals Usa, Inc. Method of preparing a 5H-dibenz(b,f)azepine-5-carboxamide
WO2005066133A2 (fr) * 2003-10-20 2005-07-21 Amoli Organics Ltd. Nouveau procede de preparation de 10-oxo-10, 11-dihydro-5h-dibenz [b,f]azepine-5-carboxamide (oxcarbazepine) via le chlorure de 10-methoxy-5h-dibenz[b,f] azepine-5-carbonyle comme intermediaire
ITMI20040452A1 (it) * 2004-03-09 2004-06-09 Clariant Lsm Italia Spa Processo per la preparazione di oxcarbazepina
US7459553B2 (en) * 2004-03-11 2008-12-02 Glenmark Generics Ltd. Process for the preparation of carboxamide compounds
US7982032B2 (en) * 2004-03-11 2011-07-19 Sun Pharmaceutical Industries Limited Process for the preparation of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide
CA2471666C (fr) * 2004-06-18 2009-10-13 Apotex Pharmachem Inc. Methode de synthese amelioree d'oxcarbazepine et d'intermediaires connexes
US20070032647A1 (en) * 2004-10-15 2007-02-08 Amoli Organics Ltd. Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride
GB2422149A (en) 2005-01-14 2006-07-19 Portela & Ca Sa Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
CN101489560B (zh) * 2006-04-26 2015-11-25 苏佩努斯制药公司 具有s形释放曲线的奥卡西平控释制剂
WO2007141798A1 (fr) * 2006-06-07 2007-12-13 Jubilant Organosys Limited Procédé de production d'oxcarbazépine via un intermédiaire 11-alcoxy-10-halogéno-dihydroiminostilbène
WO2008012837A1 (fr) * 2006-07-24 2008-01-31 Jubilant Organosys Limited Procédé de production de 10-oxo-1o, 11-dihydro-5h- dibenz[b, f] azepine-5-carboxamide à partir de 5-cyanoiminostilbène
WO2009139001A2 (fr) * 2008-05-08 2009-11-19 Matrix Laboratories Ltd Procédé perfectionné de fabrication d'oxcarbazépine
WO2012142302A2 (fr) 2011-04-13 2012-10-18 Codexis, Inc. Procédé biocatalytique permettant de préparer de l'eslicarbazépine et ses analogues
WO2013008194A2 (fr) 2011-07-13 2013-01-17 Ranbaxy Laboratories Limited Procédé de préparation et de purification d'acétate d'eslicarbazépine et de ses intermédiaires
US20150232426A1 (en) 2012-09-26 2015-08-20 Ranbaxy Laboratories Limited Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FR2045705A1 (en) * 1969-06-24 1971-03-05 Rhone Poulenc Sa Fungicidal dihydrodibenzaxepine derivs
US4847374A (en) * 1987-01-27 1989-07-11 Ciba-Geigy Corporation Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DE4307181C1 (de) * 1993-03-08 1994-11-10 Dresden Arzneimittel Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid

Also Published As

Publication number Publication date
IT1272897B (it) 1997-07-01
DE69609843D1 (de) 2000-09-21
DE69609843T2 (de) 2001-01-18
EP0847390B1 (fr) 2000-08-16
AU4347996A (en) 1996-07-31
ITMI950056A1 (it) 1996-07-13
EP0847390A1 (fr) 1998-06-17
ATE195518T1 (de) 2000-09-15
WO1996021649A1 (fr) 1996-07-18
ES2150093T3 (es) 2000-11-16
ITMI950056A0 (it) 1995-01-13
GR3034844T3 (en) 2001-02-28
US5808058A (en) 1998-09-15
PT847390E (pt) 2000-11-30

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