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DK0728146T3 - Conotoxinpeptider - Google Patents

Conotoxinpeptider

Info

Publication number
DK0728146T3
DK0728146T3 DK95901691T DK95901691T DK0728146T3 DK 0728146 T3 DK0728146 T3 DK 0728146T3 DK 95901691 T DK95901691 T DK 95901691T DK 95901691 T DK95901691 T DK 95901691T DK 0728146 T3 DK0728146 T3 DK 0728146T3
Authority
DK
Denmark
Prior art keywords
xaa
cys
conotoxin
peptides
alpha
Prior art date
Application number
DK95901691T
Other languages
English (en)
Inventor
Baldomero M Olivera
Lourdes J Cruz
David R Hillyard
J Michael Mcintosh
Ameurfina D Santos
Original Assignee
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utah Res Found filed Critical Univ Utah Res Found
Application granted granted Critical
Publication of DK0728146T3 publication Critical patent/DK0728146T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK95901691T 1993-10-19 1994-10-19 Conotoxinpeptider DK0728146T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/137,800 US5514774A (en) 1993-06-29 1993-10-19 Conotoxin peptides
PCT/US1994/011927 WO1995011256A1 (en) 1993-10-19 1994-10-19 Conotoxin peptides

Publications (1)

Publication Number Publication Date
DK0728146T3 true DK0728146T3 (da) 2002-04-22

Family

ID=22479095

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95901691T DK0728146T3 (da) 1993-10-19 1994-10-19 Conotoxinpeptider

Country Status (11)

Country Link
US (1) US5514774A (da)
EP (1) EP0728146B1 (da)
JP (1) JP3668880B2 (da)
AT (1) ATE211764T1 (da)
AU (1) AU681216B2 (da)
CA (1) CA2172989C (da)
DE (1) DE69429631T2 (da)
DK (1) DK0728146T3 (da)
ES (1) ES2169754T3 (da)
PT (1) PT728146E (da)
WO (1) WO1995011256A1 (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595972A (en) * 1993-06-29 1997-01-21 University Of Utah Research Foundation Conotoxin peptides
US5589340A (en) * 1993-06-29 1996-12-31 University Of Utah Research Foundation Process and primers for identifying nucleic acids encoding A-lineage conotoxin peptides
US5739276A (en) * 1994-10-07 1998-04-14 University Of Utah Research Foundation Conotoxin peptides
US5670622A (en) * 1996-02-15 1997-09-23 University Of Utah Research Foundation Conotoxin peptide PIIIA
US5965534A (en) * 1995-11-22 1999-10-12 Alcon Laboratories, Inc. Use of ω-conotoxin analogs for treating retinal and optic nerve head damage
US5672682A (en) * 1996-03-18 1997-09-30 University Of Utah Research Foundation Conotoxin peptide PVIIA
AU719632B2 (en) * 1996-11-08 2000-05-11 University Of Utah Research Foundation Contryphan peptides
EP0948346A4 (en) * 1996-11-18 2004-05-12 Univ Utah Res Found USE OF THE CONOTOXIN PEPTIDES IMI AND MII AS CARDIOVASCULAR ACTIVE SUBSTANCES
US5935804A (en) * 1997-03-21 1999-08-10 Laine; Roger A. Method for detecting eubacteria in biological samples with catalytically inactive murein binding enzymes
US5866682A (en) * 1997-05-15 1999-02-02 University Of Utah Research Foundation Conopeptides AuIA, AuIB and AuIC
AU1114399A (en) * 1997-10-24 1999-05-17 Case Western Reserve University Interaction of alpha-conotoxin peptides with neuronal nicotinic acetylcho line receptors
US6265541B1 (en) 1997-12-31 2001-07-24 University Of Utah Research Foundation Uses of α-conotoxin peptides
AUPP627398A0 (en) * 1998-10-02 1998-10-22 University Of Queensland, The Novel peptides - II
AU6415999A (en) * 1998-10-06 2000-04-26 Cognetix, Inc. Kappa-a conopeptides and uses therefor
US20040204362A1 (en) * 1999-01-22 2004-10-14 The University Of Utah Research Foundation Alpha-conotoxin peptides
CA2361138A1 (en) * 1999-01-22 2000-07-27 University Of Utah Research Foundation Alpha-conotoxin peptides
US6855805B2 (en) 1999-01-22 2005-02-15 University Of Utah Research Foundation α-conotoxin peptides
WO2000044776A1 (en) * 1999-01-29 2000-08-03 University Of Utah Research Foundation Alpha-conotoxin peptides
EP1852440A1 (en) * 1999-01-29 2007-11-07 University of Utah Research Foundation Alpha-conotoxin peptides
US6797808B1 (en) 1999-01-29 2004-09-28 University Of Utah Research Foundation α-conotoxin peptides
EP1151100A4 (en) * 1999-02-04 2002-07-17 Univ Utah Res Found TAU-CONOTOXIN PEPTIDE
AU783925B2 (en) 1999-08-10 2005-12-22 Uab Research Foundation Method of treating traumatic brain and spinal cord injuries and other neurogenic conditions using non-steroidal anti-inflammatory drugs and naturally occurring conotoxins
US20030109670A1 (en) * 2001-02-09 2003-06-12 University Of Utah Research Foundation Cone snail peptides
AU2002245934B2 (en) * 2001-03-29 2008-05-01 John Down Alpha conotoxin peptides with analgesic properties
AUPR409401A0 (en) * 2001-03-29 2001-04-26 University Of Melbourne, The Analgesic compound
US6958151B2 (en) * 2002-03-15 2005-10-25 Board Of Regents, The University Of Texas System Miniprotein ligands and other polypeptides and methods for making and using same
US20040018580A1 (en) * 2002-05-10 2004-01-29 Chai Karl X. Synthetic substrates for prostasin
AU2003263853A1 (en) * 2002-08-16 2004-03-03 Board Of Regents The University Of Texas System Compositions and methods related to flavivirus envelope protein domain iii antigens
JP4095494B2 (ja) * 2003-05-30 2008-06-04 キヤノン株式会社 眼科画像処理装置及び処理方法
EP1791857A4 (en) * 2004-09-09 2009-04-08 Univ Singapore CONFORMATION CHANGE IN TOXIN FOLDING AND USES THEREOF
US7387997B2 (en) * 2004-11-09 2008-06-17 University Of Utah α-conotoxin MII analogues
SG10201601789TA (en) 2011-03-16 2016-04-28 Amgen Inc Potent And Selective Inhibitors Of Nav1.3 And Nav1.7
US10344060B2 (en) 2013-03-12 2019-07-09 Amgen Inc. Potent and selective inhibitors of Nav1.7
US9636418B2 (en) 2013-03-12 2017-05-02 Amgen Inc. Potent and selective inhibitors of NAV1.7
WO2014194284A1 (en) * 2013-05-31 2014-12-04 Mcintosh J Michael Conotoxin peptides, pharmaceutical compositions and uses thereof
CN103554226B (zh) * 2013-10-30 2016-02-03 南京工业大学 一种α-芋螺毒素MI的全固相合成方法
US20170209553A1 (en) 2016-01-22 2017-07-27 Transderm, Inc. Delivery of botulinum with microneedle arrays
CN110981967B (zh) * 2019-11-22 2022-10-14 中国海洋大学 α-芋螺毒素Mr1.1的二聚体、合成方法及应用
JP2023523899A (ja) * 2020-04-09 2023-06-08 ジーエルオー ファーマ,インク. ニコチン性アセチルコリン受容体活性を阻害するためのペプチド組成物および方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051403A (en) * 1989-11-22 1991-09-24 Neurex Corporation Method of treating ischemia-related neuronal damage
US5231011A (en) * 1991-04-18 1993-07-27 University Of Utah Segregated folding determinants for small disulfide-rich peptides
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US5432155A (en) * 1993-06-29 1995-07-11 The Salk Institute For Biological Studies Conotoxins I

Also Published As

Publication number Publication date
DE69429631D1 (en) 2002-02-14
CA2172989C (en) 2002-09-17
JPH10509415A (ja) 1998-09-14
PT728146E (pt) 2002-05-31
EP0728146A1 (en) 1996-08-28
EP0728146A4 (en) 1998-08-19
AU681216B2 (en) 1997-08-21
JP3668880B2 (ja) 2005-07-06
EP0728146B1 (en) 2002-01-09
US5514774A (en) 1996-05-07
CA2172989A1 (en) 1995-04-27
ATE211764T1 (de) 2002-01-15
DE69429631T2 (de) 2002-09-12
AU1083195A (en) 1995-05-08
ES2169754T3 (es) 2002-07-16
WO1995011256A1 (en) 1995-04-27

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