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DK0710233T3 - Heteroarylcycloalkenylhydroxyurinstoffer - Google Patents

Heteroarylcycloalkenylhydroxyurinstoffer

Info

Publication number
DK0710233T3
DK0710233T3 DK94919852T DK94919852T DK0710233T3 DK 0710233 T3 DK0710233 T3 DK 0710233T3 DK 94919852 T DK94919852 T DK 94919852T DK 94919852 T DK94919852 T DK 94919852T DK 0710233 T3 DK0710233 T3 DK 0710233T3
Authority
DK
Denmark
Prior art keywords
alkyl
hydrogen
pct
fluoro
chloro
Prior art date
Application number
DK94919852T
Other languages
English (en)
Inventor
Akiyoshi Kawai
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0710233T3 publication Critical patent/DK0710233T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pyridine Compounds (AREA)
DK94919852T 1993-07-20 1994-07-05 Heteroarylcycloalkenylhydroxyurinstoffer DK0710233T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17940193 1993-07-20
PCT/JP1994/001093 WO1995003292A1 (en) 1993-07-20 1994-07-05 Heteroaryl cycloalkenyl hydroxyureas

Publications (1)

Publication Number Publication Date
DK0710233T3 true DK0710233T3 (da) 2000-01-03

Family

ID=16065226

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94919852T DK0710233T3 (da) 1993-07-20 1994-07-05 Heteroarylcycloalkenylhydroxyurinstoffer

Country Status (11)

Country Link
US (1) US5665768A (da)
EP (1) EP0710233B1 (da)
JP (1) JPH08511029A (da)
AT (1) ATE185563T1 (da)
CA (1) CA2167715C (da)
DE (1) DE69421183T2 (da)
DK (1) DK0710233T3 (da)
ES (1) ES2139746T3 (da)
FI (1) FI943420L (da)
GR (1) GR3032238T3 (da)
WO (1) WO1995003292A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996016054A1 (en) * 1994-11-18 1996-05-30 Pfizer Pharmaceuticals Inc. Cycloalkenyl-n-hydroxyureas
CA2388844A1 (en) * 1999-11-12 2001-05-25 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
US20040043052A1 (en) 2002-05-24 2004-03-04 Angiotech Pharmaceuticals, Inc. Compositions and methods for coating medical implants
CA2511521C (en) 2002-12-30 2012-02-07 Angiotech International Ag Drug delivery from rapid gelling polymer composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334975C (en) * 1987-11-13 1995-03-28 James H. Holms Furan and pyrrole containing lipoxygenase inhibiting compounds
GB9025514D0 (en) * 1990-11-23 1991-01-09 Wellcome Found Anti-inflammatory compounds
JP3007138B2 (ja) * 1990-11-27 2000-02-07 ファイザー製薬株式会社 新規なヒドロキサム酸とn―ヒドロキシ尿素誘導体およびそれらの組成物
JPH0717612B2 (ja) * 1991-06-28 1995-03-01 ファイザー製薬株式会社 新規なテトラヒドロベンズアゼピン誘導体
JP2989951B2 (ja) * 1991-10-25 1999-12-13 ファイザー製薬株式会社 新規なシクロアルキル尿素誘導体および組成物
US5521212A (en) * 1991-12-13 1996-05-28 Pfizer Inc. Cyclopropyl N-hydroxyurea and N-hydroxyacetamides which inhibit lipoxygenase
US5169854A (en) * 1992-02-26 1992-12-08 Abbott Laboratories N-substituted-furylalkenyl hydroxamic acid and N-hydroxyurea compounds having lipoxygenase inhibitory activity
US5187192A (en) * 1992-03-13 1993-02-16 Abbott Laboratories Cyclobutyl derivatives having lipoxygenase inhibitory activity

Also Published As

Publication number Publication date
FI943420A7 (fi) 1995-01-21
EP0710233B1 (en) 1999-10-13
ATE185563T1 (de) 1999-10-15
FI943420L (fi) 1995-01-21
WO1995003292A1 (en) 1995-02-02
JPH08511029A (ja) 1996-11-19
DE69421183D1 (de) 1999-11-18
CA2167715C (en) 1998-10-06
CA2167715A1 (en) 1995-02-02
FI943420A0 (fi) 1994-07-19
GR3032238T3 (en) 2000-04-27
ES2139746T3 (es) 2000-02-16
EP0710233A1 (en) 1996-05-08
DE69421183T2 (de) 2000-01-20
US5665768A (en) 1997-09-09

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