DK0705256T3 - Fremgangsmåde til fremstilling af N-acetylneuraminsyrederivater - Google Patents
Fremgangsmåde til fremstilling af N-acetylneuraminsyrederivaterInfo
- Publication number
- DK0705256T3 DK0705256T3 DK94918871T DK94918871T DK0705256T3 DK 0705256 T3 DK0705256 T3 DK 0705256T3 DK 94918871 T DK94918871 T DK 94918871T DK 94918871 T DK94918871 T DK 94918871T DK 0705256 T3 DK0705256 T3 DK 0705256T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- preparation
- acid derivatives
- sec
- compound
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Pyrane Compounds (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939312531A GB9312531D0 (en) | 1993-06-17 | 1993-06-17 | Process |
| PCT/EP1994/001940 WO1995000503A1 (en) | 1993-06-17 | 1994-06-15 | Process for the preparation of n-acetyl neuraminic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0705256T3 true DK0705256T3 (da) | 1999-06-23 |
Family
ID=10737336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94918871T DK0705256T3 (da) | 1993-06-17 | 1994-06-15 | Fremgangsmåde til fremstilling af N-acetylneuraminsyrederivater |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5597933A (da) |
| EP (1) | EP0705256B1 (da) |
| JP (1) | JP3298644B2 (da) |
| CN (1) | CN1061343C (da) |
| AT (1) | ATE172198T1 (da) |
| AU (1) | AU687825B2 (da) |
| CA (1) | CA2165329C (da) |
| CY (1) | CY2184B1 (da) |
| DE (1) | DE69413974T2 (da) |
| DK (1) | DK0705256T3 (da) |
| ES (1) | ES2125463T3 (da) |
| FI (1) | FI111941B (da) |
| GB (1) | GB9312531D0 (da) |
| HU (1) | HU213451B (da) |
| NO (1) | NO312675B1 (da) |
| SG (1) | SG48162A1 (da) |
| WO (1) | WO1995000503A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866601A (en) * | 1995-02-27 | 1999-02-02 | Gilead Sciences, Inc. | Carbocyclic compounds |
| KR100447096B1 (ko) * | 1995-02-27 | 2005-10-11 | 갈리드사이언스인코오퍼레이티드 | 바이러스성또는세균성뉴라미니다제의신규한선택적저해제 |
| US5763483A (en) * | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| ATE211468T1 (de) * | 1996-07-22 | 2002-01-15 | Sankyo Co | Neuraminsäuredervate, ihre herstellung und medizinische verwendung |
| US6518438B2 (en) | 1996-08-23 | 2003-02-11 | Gilead Sciences, Inc. | Preparation of cyclohexene carboxylate derivatives |
| US5859284A (en) * | 1996-08-23 | 1999-01-12 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| US5994377A (en) * | 1996-10-21 | 1999-11-30 | Gilead Sciences, Inc. | Piperidine compounds |
| US5886213A (en) * | 1997-08-22 | 1999-03-23 | Gilead Sciences, Inc. | Preparation of carbocyclic compounds |
| US20040053999A1 (en) * | 1997-09-17 | 2004-03-18 | Bischofberger Norbert W. | Novel compounds and methods for synthesis and therapy |
| TW477783B (en) * | 1997-12-12 | 2002-03-01 | Gilead Sciences Inc | Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same |
| SE9904289D0 (sv) * | 1999-11-26 | 1999-11-26 | Niklas Arnberg | Method and camposition for the treatment of adenovairal ocular infections |
| US7636596B2 (en) * | 2002-12-20 | 2009-12-22 | Medtronic, Inc. | Organ access device and method |
| KR101142052B1 (ko) | 2010-02-18 | 2012-07-19 | 한미약품 주식회사 | 자나미비어의 제조방법 |
| CN101962375B (zh) * | 2010-09-21 | 2012-05-23 | 仙居县圃瑞药业有限公司 | 扎那米韦中间体叠氮还原工艺方法 |
| WO2015173701A2 (en) | 2014-05-12 | 2015-11-19 | Glaxosmithkline Intellectual Property (No. 2) Limited | Pharmaceutical compositions for treating infectious diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP249A (en) * | 1990-04-24 | 1993-03-17 | Biota Scient Management Pty Ltd | Anti-viral compounds. |
| GB9126725D0 (en) * | 1991-12-17 | 1992-02-12 | Glaxo Group Ltd | Process |
-
1993
- 1993-06-17 GB GB939312531A patent/GB9312531D0/en active Pending
-
1994
- 1994-06-15 AU AU70006/94A patent/AU687825B2/en not_active Expired
- 1994-06-15 SG SG1996007494A patent/SG48162A1/en unknown
- 1994-06-15 DK DK94918871T patent/DK0705256T3/da active
- 1994-06-15 WO PCT/EP1994/001940 patent/WO1995000503A1/en not_active Ceased
- 1994-06-15 DE DE69413974T patent/DE69413974T2/de not_active Expired - Lifetime
- 1994-06-15 ES ES94918871T patent/ES2125463T3/es not_active Expired - Lifetime
- 1994-06-15 US US08/549,820 patent/US5597933A/en not_active Expired - Lifetime
- 1994-06-15 CN CN94192472A patent/CN1061343C/zh not_active Expired - Lifetime
- 1994-06-15 HU HU9503599A patent/HU213451B/hu unknown
- 1994-06-15 CA CA002165329A patent/CA2165329C/en not_active Expired - Lifetime
- 1994-06-15 JP JP50240795A patent/JP3298644B2/ja not_active Expired - Lifetime
- 1994-06-15 AT AT94918871T patent/ATE172198T1/de active
- 1994-06-15 EP EP94918871A patent/EP0705256B1/en not_active Expired - Lifetime
-
1995
- 1995-12-14 FI FI955993A patent/FI111941B/fi not_active IP Right Cessation
- 1995-12-15 NO NO19955124A patent/NO312675B1/no not_active IP Right Cessation
-
1999
- 1999-01-14 CY CY9900002A patent/CY2184B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI111941B (fi) | 2003-10-15 |
| JP3298644B2 (ja) | 2002-07-02 |
| EP0705256A1 (en) | 1996-04-10 |
| CA2165329C (en) | 2002-08-20 |
| NO312675B1 (no) | 2002-06-17 |
| ES2125463T3 (es) | 1999-03-01 |
| DE69413974T2 (de) | 1999-03-11 |
| HUT73561A (en) | 1996-08-28 |
| EP0705256B1 (en) | 1998-10-14 |
| CY2184B1 (en) | 2002-11-08 |
| HK1011995A1 (en) | 1999-07-23 |
| GB9312531D0 (en) | 1993-08-04 |
| AU7000694A (en) | 1995-01-17 |
| JPH08511550A (ja) | 1996-12-03 |
| WO1995000503A1 (en) | 1995-01-05 |
| CN1125441A (zh) | 1996-06-26 |
| SG48162A1 (en) | 1998-04-17 |
| DE69413974D1 (de) | 1998-11-19 |
| NO955124D0 (no) | 1995-12-15 |
| CA2165329A1 (en) | 1995-01-05 |
| AU687825B2 (en) | 1998-03-05 |
| CN1061343C (zh) | 2001-01-31 |
| US5597933A (en) | 1997-01-28 |
| FI955993L (fi) | 1995-12-14 |
| HU9503599D0 (en) | 1996-02-28 |
| ATE172198T1 (de) | 1998-10-15 |
| FI955993A0 (fi) | 1995-12-14 |
| HU213451B (en) | 1997-06-30 |
| NO955124L (no) | 1995-12-15 |
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