DK0700383T3 - Hidtil ukendte 1-phenylalkanon 5-HT4 receptorligander - Google Patents

Hidtil ukendte 1-phenylalkanon 5-HT4 receptorligander

Info

Publication number: DK0700383T3
Authority: DK; Denmark
Prior art keywords: substituted; alkyloxy; receptor ligands; phenylalkanone; new
Prior art date: 1993-05-26

Application number

DK94918070T

Other languages

Danish (da)

English (en)

Inventor

Robin D Clark

Richard Eglen

Alam Jahangir

Aaron B Miller

John O Gardner

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-26

Filing date

1994-05-25

Publication date

1999-06-14

1994-05-25 Application filed by Syntex Inc filed Critical Syntex Inc

1999-06-14 Application granted granted Critical

1999-06-14 Publication of DK0700383T3 publication Critical patent/DK0700383T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/10—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Reproductive Health (AREA)
Biomedical Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

DK94918070T 1993-05-26 1994-05-25 Hidtil ukendte 1-phenylalkanon 5-HT4 receptorligander DK0700383T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US6776693A	1993-05-26	1993-05-26
US22860294A	1994-04-26	1994-04-26
PCT/US1994/005718 WO1994027965A1 (fr)	1993-05-26	1994-05-25	Nouveaux ligands 1-phenylalcanone du recepteur de 5-ht4

Publications (1)

Publication Number	Publication Date
DK0700383T3 true DK0700383T3 (da)	1999-06-14

Family

ID=26748233

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94918070T DK0700383T3 (da)	1993-05-26	1994-05-25	Hidtil ukendte 1-phenylalkanon 5-HT4 receptorligander

Country Status (23)

Country	Link
US (1)	US5763458A (fr)
EP (1)	EP0700383B1 (fr)
JP (1)	JP3935199B2 (fr)
KR (1)	KR100322325B1 (fr)
CN (1)	CN1058262C (fr)
AT (1)	ATE171446T1 (fr)
AU (1)	AU680004B2 (fr)
BR (1)	BR9406724A (fr)
CA (1)	CA2163747C (fr)
CZ (1)	CZ289752B6 (fr)
DE (1)	DE69413535T2 (fr)
DK (1)	DK0700383T3 (fr)
ES (1)	ES2121210T3 (fr)
FI (1)	FI109903B (fr)
HU (2)	HUT74870A (fr)
IL (1)	IL109776A (fr)
NO (1)	NO306109B1 (fr)
NZ (1)	NZ267296A (fr)
PL (1)	PL180336B1 (fr)
RU (1)	RU2170228C2 (fr)
TW (1)	TW248554B (fr)
UA (1)	UA35618C2 (fr)
WO (1)	WO1994027965A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9310582D0 (en) *	1993-05-22	1993-07-07	Smithkline Beecham Plc	Pharmaceuticals
JP4028894B2 (ja) *	1996-08-09	2007-12-26	エーザイ・アール・アンド・ディー・マネジメント株式会社	ベンゾピペリジン誘導体
IT1304874B1 (it) *	1998-07-17	2001-04-05	Univ Firenze	Amminoalcoli,amminochetoni e loro derivati,loro preparazione ed usocome farmaci per le patologie del sistema nervoso centrale (snc) e
EP1112270B1 (fr) *	1998-09-10	2007-03-21	F. Hoffmann-La Roche Ag	Dihydrobenzodioxine carboxamide et derives de cetone utilises comme antagonistes du recepteur 5-ht4
US20020177593A1 (en)	1998-09-30	2002-11-28	Yuji Ishihara	Agents and crystals for improving excretory potency of urinary bladder
AU758802B2 (en) *	1998-09-30	2003-03-27	Takeda Pharmaceutical Company Limited	Drugs for improving vesical excretory strength
PL365048A1 (en) *	2000-08-07	2004-12-27	Laboratoire Glaxosmithkline S.A.S.	Use of 5ht4 receptor antagonists in the manufacture of a medicament for the prophylaxis or treatment of atrial fibrillation
US6924285B2 (en)	2002-03-30	2005-08-02	Boehringer Ingelheim Pharma Gmbh & Co.	Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
GB0317665D0 (en)	2003-07-29	2003-09-03	Astrazeneca Ab	Qinazoline derivatives
EP1664042A1 (fr) *	2003-09-03	2006-06-07	Galapagos N.V.	Derives d'imidazo 1,5-a\|pyridine ou d'imidazo 1,5-a\|piperidine et leur utilisation dans la preparation d'un medicament dirige contre les troubles lies au recepteur 5-ht2a
WO2005021505A1 (fr) *	2003-09-03	2005-03-10	Galapagos Nv	Nouveau 4-piperidine-carboxamide et leur utilisation pour preparer des medicaments contre des troubles lies au recepteur de la 5-ht2a
US20050215589A1 (en) *	2003-09-03	2005-09-29	Roger Crossley	Inhibitors of 5-HT2A receptor
CA2538752C (fr)	2003-09-19	2011-08-02	Astrazeneca Ab	Derives de quinazoline
JP5054544B2 (ja)	2005-02-26	2012-10-24	アストラゼネカアクチボラグ	チロシンキナーゼ阻害剤としてのキナゾリン誘導体
GB0519879D0 (en) *	2005-09-30	2005-11-09	Astrazeneca Ab	Chemical process
EP1921070A1 (fr)	2006-11-10	2008-05-14	Boehringer Ingelheim Pharma GmbH & Co. KG	heterocycles bicycliques, medicaments á base de ces composes, leur usage et procédé pour leur preparation
MX2009007610A (es)	2007-02-06	2009-07-24	Boehringer Ingelheim Int	Heterociclicos biciclicos, medicamentos que contienen estos compuestos, su utilizacion y procedimientos para su preparacion.
EP2245026B1 (fr)	2008-02-07	2012-08-01	Boehringer Ingelheim International GmbH	Hétérocycles spirocycliques, médicaments contenant ces composés, leur utilisation et procédé pour les produire
US8088782B2 (en)	2008-05-13	2012-01-03	Astrazeneca Ab	Crystalline 4-(3-chloro-2-fluoroanilino)-7 methoxy-6-{[1-(N-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline difumarate form A
US8648191B2 (en)	2008-08-08	2014-02-11	Boehringer Ingelheim International Gmbh	Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
FR3006686A1 (fr)	2013-06-05	2014-12-12	Univ Caen	Composes inhibiteurs de l'acetylcholinesterase et agonistes des recepteurs serotoninergiques 5ht4, a effet promnesiant, leurs procedes de preparation et compositions pharmaceutiques les contenant

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1011750A (en) *	1972-04-15	1977-06-07	Badische Anilin- And Soda-Fabrik Aktiengesellschaft	Electrophilic substitution of nitrosamines
FR2443246A1 (fr) *	1978-12-05	1980-07-04	Pharmindustrie	Nouveaux medicaments a base de derives de la phenyl-1 (piperidyl-4)-3 propanone-1
FR2459795A1 (fr) *	1979-06-26	1981-01-16	Pharmindustrie	Nouveaux derives de la phenyl-1 (piperidyl-4)-3 propanone-1 utilisables comme medicaments
FR2504136A1 (fr) *	1981-04-15	1982-10-22	Lafon Labor	(2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation
FR2534916B1 (fr) *	1982-10-26	1985-11-22	Lafon Labor	Nouveaux derives de phenyl-(3-aminopropyl)-cetone, utilisation en therapeutique et procede de preparation
JPS61249954A (ja) *	1985-04-26	1986-11-07	Aguro Kanesho Kk	プロピオン酸誘導体
US4851423A (en) *	1986-12-10	1989-07-25	Schering Corporation	Pharmaceutically active compounds
CA1289166C (fr) *	1987-04-29	1991-09-17	Paul H. Martin	Porte-rideau pour camionnette
GB2240476B (en) *	1987-07-11	1992-03-18	Sandoz Ltd	5 ht-3 antagonists for the prevention or reduction of dependence
US5116846A (en) *	1990-03-28	1992-05-26	Du Pont Merck Pharmaceutical Company	N-aralkyl piperidine derivatives as psychotropic drugs
JPH05241306A (ja) *	1992-03-02	1993-09-21	Fuji Photo Film Co Ltd	ハロゲン化銀写真感光材料
WO1994007890A1 (fr) *	1992-10-05	1994-04-14	Ube Industries, Ltd.	Compose pyrimidine

1994
- 1994-05-25 ES ES94918070T patent/ES2121210T3/es not_active Expired - Lifetime
- 1994-05-25 RU RU95122587/04A patent/RU2170228C2/ru not_active IP Right Cessation
- 1994-05-25 DE DE69413535T patent/DE69413535T2/de not_active Expired - Lifetime
- 1994-05-25 AU AU69548/94A patent/AU680004B2/en not_active Ceased
- 1994-05-25 BR BR9406724A patent/BR9406724A/pt not_active Application Discontinuation
- 1994-05-25 IL IL109776A patent/IL109776A/en not_active IP Right Cessation
- 1994-05-25 JP JP50083695A patent/JP3935199B2/ja not_active Expired - Fee Related
- 1994-05-25 UA UA95114906A patent/UA35618C2/uk unknown
- 1994-05-25 TW TW083104739A patent/TW248554B/zh active
- 1994-05-25 CZ CZ19952780A patent/CZ289752B6/cs not_active IP Right Cessation
- 1994-05-25 PL PL94311723A patent/PL180336B1/pl not_active IP Right Cessation
- 1994-05-25 NZ NZ267296A patent/NZ267296A/en unknown
- 1994-05-25 HU HU9503357A patent/HUT74870A/hu unknown
- 1994-05-25 CA CA002163747A patent/CA2163747C/fr not_active Expired - Fee Related
- 1994-05-25 AT AT94918070T patent/ATE171446T1/de not_active IP Right Cessation
- 1994-05-25 DK DK94918070T patent/DK0700383T3/da active
- 1994-05-25 WO PCT/US1994/005718 patent/WO1994027965A1/fr not_active Ceased
- 1994-05-25 CN CN94192219A patent/CN1058262C/zh not_active Expired - Fee Related
- 1994-05-25 EP EP94918070A patent/EP0700383B1/fr not_active Expired - Lifetime
- 1994-05-25 KR KR1019950705242A patent/KR100322325B1/ko not_active Expired - Fee Related
1995
- 1995-04-24 HU HU95P/P00112P patent/HU211542A9/hu unknown
- 1995-05-31 US US08/456,168 patent/US5763458A/en not_active Expired - Lifetime
- 1995-11-24 NO NO954761A patent/NO306109B1/no unknown
- 1995-11-24 FI FI955660A patent/FI109903B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU211542A9 (en)	1995-12-28
IL109776A (en)	1998-03-10
CZ289752B6 (cs)	2002-03-13
JPH08510743A (ja)	1996-11-12
EP0700383A1 (fr)	1996-03-13
DE69413535T2 (de)	1999-02-11
CN1124485A (zh)	1996-06-12
CZ278095A3 (en)	1996-06-12
FI955660A0 (fi)	1995-11-24
UA35618C2 (uk)	2001-04-16
FI955660L (fi)	1995-11-24
BR9406724A (pt)	1996-02-06
FI109903B (fi)	2002-10-31
JP3935199B2 (ja)	2007-06-20
HU9503357D0 (en)	1996-01-29
AU680004B2 (en)	1997-07-17
WO1994027965A1 (fr)	1994-12-08
NO306109B1 (no)	1999-09-20
ES2121210T3 (es)	1998-11-16
CN1058262C (zh)	2000-11-08
US5763458A (en)	1998-06-09
AU6954894A (en)	1994-12-20
HUT74870A (en)	1997-02-28
PL180336B1 (pl)	2001-01-31
CA2163747A1 (fr)	1994-12-08
RU2170228C2 (ru)	2001-07-10
CA2163747C (fr)	2007-01-30
KR100322325B1 (ko)	2002-06-20
ATE171446T1 (de)	1998-10-15
NZ267296A (en)	1997-04-24
EP0700383B1 (fr)	1998-09-23
IL109776A0 (en)	1994-08-26
TW248554B (fr)	1995-06-01
NO954761L (no)	1996-01-26
DE69413535D1 (de)	1998-10-29
NO954761D0 (no)	1995-11-24
PL311723A1 (en)	1996-03-04

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