DK0799618T3 - Anvendelse af alpha1-adrenoreceptor-antagonister i fremstillingen af et medikament til forebyggelsen og behandlingen af cancer - Google Patents
Anvendelse af alpha1-adrenoreceptor-antagonister i fremstillingen af et medikament til forebyggelsen og behandlingen af cancerInfo
- Publication number
- DK0799618T3 DK0799618T3 DK97301984T DK97301984T DK0799618T3 DK 0799618 T3 DK0799618 T3 DK 0799618T3 DK 97301984 T DK97301984 T DK 97301984T DK 97301984 T DK97301984 T DK 97301984T DK 0799618 T3 DK0799618 T3 DK 0799618T3
- Authority
- DK
- Denmark
- Prior art keywords
- cancer
- drug
- alpha1
- prevention
- manufacture
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 229940082496 Adrenoreceptor antagonist Drugs 0.000 title 1
- 102000030619 alpha-1 Adrenergic Receptor Human genes 0.000 title 1
- 108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 229940122878 Alpha 1 adrenoreceptor antagonist Drugs 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1422896P | 1996-03-27 | 1996-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0799618T3 true DK0799618T3 (da) | 2005-05-30 |
Family
ID=21764236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97301984T DK0799618T3 (da) | 1996-03-27 | 1997-03-24 | Anvendelse af alpha1-adrenoreceptor-antagonister i fremstillingen af et medikament til forebyggelsen og behandlingen af cancer |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5935962A (da) |
| EP (1) | EP0799618B1 (da) |
| JP (1) | JPH10101579A (da) |
| KR (1) | KR970064607A (da) |
| AT (1) | ATE294582T1 (da) |
| AU (1) | AU733146B2 (da) |
| CA (1) | CA2201089A1 (da) |
| DE (1) | DE69733169T2 (da) |
| DK (1) | DK0799618T3 (da) |
| ES (1) | ES2242207T3 (da) |
| HU (1) | HUP9700661A3 (da) |
| IL (2) | IL120303A0 (da) |
| MY (1) | MY126321A (da) |
| NZ (1) | NZ314488A (da) |
| TW (1) | TW504386B (da) |
| ZA (1) | ZA972601B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1408154A (zh) * | 1999-01-27 | 2003-04-02 | 法国电信公司 | 验证实体真实性和/或消息的完整性和/或真实性的方法,系统,设备 |
| JP2004506683A (ja) * | 2000-08-24 | 2004-03-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | α−ジフルオロメチルオルニチン（ＤＦＭＯ）は、ヒト前立腺におけるポリアミンレベルを抑制する |
| DK1293198T3 (da) * | 2001-09-14 | 2005-06-06 | Sanol Arznei Schwarz Gmbh | Anordning til transdermal indgivelse til behandling af urinkanallidelser |
| WO2006052409A2 (en) * | 2004-10-23 | 2006-05-18 | Case Western Reserve University | Peptide and small molecule agonists of epha and their uses |
| US20090062326A1 (en) * | 2006-03-17 | 2009-03-05 | Spindel Eliot R | M3 muscarinic receptor antagonists for treatment of m3 muscarinic receptor-expressing tumors |
| WO2009131196A1 (ja) * | 2008-04-24 | 2009-10-29 | 武田薬品工業株式会社 | 置換ピロリジン誘導体およびその用途 |
| RU2587041C2 (ru) | 2010-06-30 | 2016-06-10 | Галдерма Ресерч Энд Девелопмент | Способ предотвращения или лечения опухоли кожи |
| AU2011273509A1 (en) | 2010-06-30 | 2013-06-13 | Galderma Research & Development | Use of alpha-adrenergic receptor agonist for preventing or treating skin tumor |
| US20120178757A1 (en) * | 2010-12-09 | 2012-07-12 | Nottingham University Hospitals Nhs Trust | Method For The Prevention Of Cancer Metastasis |
| GR20200100456A (el) * | 2020-08-03 | 2022-03-09 | Inderes Ltd, | Συνδυασμος φαρμακων και χρηση του στη θεραπεια του καρκινου |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4188390A (en) * | 1977-11-05 | 1980-02-12 | Pfizer Inc. | Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines |
| US4758569A (en) * | 1987-08-26 | 1988-07-19 | Pfizer Inc. | Doxazosin as an anti-atherosclerosis agent |
| DE69327128T2 (de) * | 1992-04-01 | 2000-04-20 | Pfizer, Inc. | Hydroxylierte Metaboliten und Derivate von Doxazosin gegen Atherosklerose |
| FR2694495B1 (fr) * | 1992-08-05 | 1994-09-23 | Synthelabo | Préparation pharmaceutique transdermique contenant de l'alfuzosine. |
| US5578611A (en) * | 1992-11-13 | 1996-11-26 | Synaptic Pharmaceutical Corporation | Use of α-1C specific compounds to treat benign prostatic hyperplasia |
| US5503843A (en) * | 1994-04-22 | 1996-04-02 | Flora Inc. | Transdermal delivery of alpha adrenoceptor blocking agents |
-
1997
- 1997-02-24 IL IL12030397A patent/IL120303A0/xx unknown
- 1997-03-20 IL IL12049597A patent/IL120495A/en not_active IP Right Cessation
- 1997-03-24 DK DK97301984T patent/DK0799618T3/da active
- 1997-03-24 EP EP97301984A patent/EP0799618B1/en not_active Expired - Lifetime
- 1997-03-24 ES ES97301984T patent/ES2242207T3/es not_active Expired - Lifetime
- 1997-03-24 DE DE69733169T patent/DE69733169T2/de not_active Expired - Fee Related
- 1997-03-24 AT AT97301984T patent/ATE294582T1/de not_active IP Right Cessation
- 1997-03-26 CA CA002201089A patent/CA2201089A1/en not_active Abandoned
- 1997-03-26 ZA ZA972601A patent/ZA972601B/xx unknown
- 1997-03-26 NZ NZ314488A patent/NZ314488A/xx unknown
- 1997-03-26 AU AU16569/97A patent/AU733146B2/en not_active Ceased
- 1997-03-26 HU HU9700661A patent/HUP9700661A3/hu unknown
- 1997-03-26 KR KR1019970010501A patent/KR970064607A/ko not_active Ceased
- 1997-03-26 MY MYPI97001296A patent/MY126321A/en unknown
- 1997-03-27 JP JP9075809A patent/JPH10101579A/ja active Pending
- 1997-03-27 US US08/827,137 patent/US5935962A/en not_active Expired - Fee Related
- 1997-07-12 TW TW086110044A patent/TW504386B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69733169D1 (de) | 2005-06-09 |
| IL120303A0 (en) | 1997-06-10 |
| CA2201089A1 (en) | 1997-09-27 |
| HUP9700661A2 (hu) | 1998-11-30 |
| EP0799618A2 (en) | 1997-10-08 |
| AU733146B2 (en) | 2001-05-10 |
| IL120495A (en) | 2004-09-27 |
| ZA972601B (en) | 1998-09-28 |
| DE69733169T2 (de) | 2006-01-19 |
| ATE294582T1 (de) | 2005-05-15 |
| EP0799618B1 (en) | 2005-05-04 |
| KR970064607A (ko) | 1997-10-13 |
| US5935962A (en) | 1999-08-10 |
| TW504386B (en) | 2002-10-01 |
| HUP9700661A3 (en) | 1999-06-28 |
| AU1656997A (en) | 1997-10-02 |
| ES2242207T3 (es) | 2005-11-01 |
| NZ314488A (en) | 2000-09-29 |
| HU9700661D0 (en) | 1997-05-28 |
| EP0799618A3 (en) | 1997-11-12 |
| IL120495A0 (en) | 1997-07-13 |
| MY126321A (en) | 2006-09-29 |
| JPH10101579A (ja) | 1998-04-21 |
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