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DK0777671T3 - Spiro-azabicykliske forbindelser - Google Patents

Spiro-azabicykliske forbindelser

Info

Publication number
DK0777671T3
DK0777671T3 DK95930755T DK95930755T DK0777671T3 DK 0777671 T3 DK0777671 T3 DK 0777671T3 DK 95930755 T DK95930755 T DK 95930755T DK 95930755 T DK95930755 T DK 95930755T DK 0777671 T3 DK0777671 T3 DK 0777671T3
Authority
DK
Denmark
Prior art keywords
spiro
azabicyclic compounds
azabicyclic
compounds
Prior art date
Application number
DK95930755T
Other languages
English (en)
Inventor
Michael Balestra
John Charles Gordon
Ronald Conrad Griffith
Robert John Murray
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9417084A external-priority patent/GB9417084D0/en
Priority claimed from GBGB9504627.2A external-priority patent/GB9504627D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK0777671T3 publication Critical patent/DK0777671T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK95930755T 1994-08-24 1995-08-22 Spiro-azabicykliske forbindelser DK0777671T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9417084A GB9417084D0 (en) 1994-08-24 1994-08-24 Compounds useful in therapy
GBGB9504627.2A GB9504627D0 (en) 1995-03-08 1995-03-08 Compounds for use in therapy
PCT/SE1995/000937 WO1996006098A1 (en) 1994-08-24 1995-08-22 Spiro-azabicyclic compounds useful in therapy

Publications (1)

Publication Number Publication Date
DK0777671T3 true DK0777671T3 (da) 2000-07-24

Family

ID=26305509

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95930755T DK0777671T3 (da) 1994-08-24 1995-08-22 Spiro-azabicykliske forbindelser

Country Status (33)

Country Link
US (2) US5902814A (da)
EP (1) EP0777671B1 (da)
JP (1) JP3708962B2 (da)
KR (1) KR100366331B1 (da)
CN (2) CN1056846C (da)
AR (1) AR031828A2 (da)
AT (1) ATE192157T1 (da)
AU (1) AU690735B2 (da)
BR (1) BR9508751A (da)
CA (1) CA2196995C (da)
CZ (1) CZ289512B6 (da)
DE (1) DE69516524T2 (da)
DK (1) DK0777671T3 (da)
EE (1) EE03399B1 (da)
EG (1) EG24222A (da)
ES (1) ES2145922T3 (da)
FI (1) FI112868B (da)
GR (1) GR3033878T3 (da)
HU (1) HUT77352A (da)
IL (1) IL115039A (da)
IS (1) IS1852B (da)
MX (1) MX9701292A (da)
NO (1) NO307707B1 (da)
NZ (1) NZ292289A (da)
PL (1) PL183933B1 (da)
PT (1) PT777671E (da)
RU (1) RU2148058C1 (da)
SA (1) SA95160370B1 (da)
SK (1) SK282366B6 (da)
TR (1) TR199501053A2 (da)
TW (1) TW397837B (da)
UA (1) UA54375C2 (da)
WO (1) WO1996006098A1 (da)

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JP2005510482A (ja) * 2001-10-16 2005-04-21 アストラゼネカ・アクチエボラーグ 線維筋痛症候群の治療方法
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SE0202598D0 (sv) * 2002-09-02 2002-09-02 Astrazeneca Ab Alpha-7 Nicotinic receptor agonists and statins in combination
JP4750421B2 (ja) * 2002-12-06 2011-08-17 ノース ショア−ロング アイランド ジュ−イッシュ リサ−チ インスティチュ−ト α７受容体結合コリン作動性アゴニストを用いる炎症の阻害
US7238715B2 (en) * 2002-12-06 2007-07-03 The Feinstein Institute For Medical Research Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists
AU2004255920B2 (en) * 2003-07-08 2008-05-15 Astrazeneca Ab Spiro [1-azabicyclo [2.2.2] octan-3,5'-oxazolidin]-2'-one derivatives with affinity to the alpha7 nicotinic acetylcholine receptor
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US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
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Also Published As

Publication number Publication date
AU690735B2 (en) 1998-04-30
EP0777671A1 (en) 1997-06-11
IL115039A0 (en) 1995-12-08
EE9700039A (et) 1997-08-15
ES2145922T3 (es) 2000-07-16
SK21697A3 (en) 1997-09-10
CA2196995C (en) 2008-05-13
US6051581A (en) 2000-04-18
IL115039A (en) 2001-08-26
PL318760A1 (en) 1997-07-07
CZ39297A3 (en) 1997-12-17
FI970762A0 (fi) 1997-02-24
NO307707B1 (no) 2000-05-15
NZ292289A (en) 1998-05-27
FI970762L (fi) 1997-02-24
HUT77352A (hu) 1998-03-30
EE03399B1 (et) 2001-04-16
CA2196995A1 (en) 1996-02-29
PT777671E (pt) 2000-08-31
JP3708962B2 (ja) 2005-10-19
IS4424A (is) 1997-02-03
UA54375C2 (uk) 2003-03-17
NO970800D0 (no) 1997-02-21
HK1010370A1 (en) 1999-06-17
AR031828A2 (es) 2003-10-08
CN1099419C (zh) 2003-01-22
MX9701292A (es) 1997-05-31
DE69516524T2 (de) 2001-01-18
GR3033878T3 (en) 2000-11-30
EG24222A (en) 2008-11-10
SA95160370B1 (ar) 2006-06-04
RU2148058C1 (ru) 2000-04-27
DE69516524D1 (de) 2000-05-31
JPH10504561A (ja) 1998-05-06
CZ289512B6 (cs) 2002-02-13
CN1284505A (zh) 2001-02-21
WO1996006098A1 (en) 1996-02-29
TR199501053A2 (tr) 1996-06-21
CN1056846C (zh) 2000-09-27
PL183933B1 (pl) 2002-08-30
TW397837B (en) 2000-07-11
US5902814A (en) 1999-05-11
CN1159808A (zh) 1997-09-17
AU3401895A (en) 1996-03-14
ATE192157T1 (de) 2000-05-15
EP0777671B1 (en) 2000-04-26
IS1852B (is) 2003-02-21
SK282366B6 (sk) 2002-01-07
BR9508751A (pt) 1997-08-12
NO970800L (no) 1997-02-21
FI112868B (fi) 2004-01-30
KR100366331B1 (ko) 2003-04-10

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