[go: up one dir, main page]

DK0775749T4 - Subtilisinmutanter - Google Patents

Subtilisinmutanter

Info

Publication number
DK0775749T4
DK0775749T4 DK96120247T DK96120247T DK0775749T4 DK 0775749 T4 DK0775749 T4 DK 0775749T4 DK 96120247 T DK96120247 T DK 96120247T DK 96120247 T DK96120247 T DK 96120247T DK 0775749 T4 DK0775749 T4 DK 0775749T4
Authority
DK
Denmark
Prior art keywords
subtilisin
Prior art date
Application number
DK96120247T
Other languages
English (en)
Other versions
DK0775749T3 (da
Inventor
Robert Mark Caldwell
David Aaron Estell
Thomas Paul Graycar
Original Assignee
Genencor Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27028376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0775749(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genencor Int filed Critical Genencor Int
Application granted granted Critical
Publication of DK0775749T3 publication Critical patent/DK0775749T3/da
Publication of DK0775749T4 publication Critical patent/DK0775749T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38609—Protease or amylase in solid compositions only
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6418—Fatty acids by hydrolysis of fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
DK96120247T 1989-10-31 1990-10-26 Subtilisinmutanter DK0775749T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42988289A 1989-10-31 1989-10-31
US07/600,430 US5185258A (en) 1984-05-29 1990-10-19 Subtilisin mutants
PCT/US1990/006084 WO1991006637A1 (en) 1989-10-31 1990-10-26 Subtilisin mutants

Publications (2)

Publication Number Publication Date
DK0775749T3 DK0775749T3 (da) 2005-09-12
DK0775749T4 true DK0775749T4 (da) 2009-07-20

Family

ID=27028376

Family Applications (2)

Application Number Title Priority Date Filing Date
DK90915958T DK0451244T3 (da) 1989-10-31 1990-10-26 Subtilisinmutanter
DK96120247T DK0775749T4 (da) 1989-10-31 1990-10-26 Subtilisinmutanter

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK90915958T DK0451244T3 (da) 1989-10-31 1990-10-26 Subtilisinmutanter

Country Status (21)

Country Link
US (1) US5185258A (da)
EP (2) EP0775749B2 (da)
JP (1) JP3335623B2 (da)
KR (1) KR970004938B1 (da)
CN (1) CN1052897A (da)
AR (1) AR244339A1 (da)
AT (2) ATE174961T1 (da)
AU (1) AU633376B2 (da)
BR (1) BR9006993A (da)
CA (1) CA2044630C (da)
DE (2) DE69032852T2 (da)
DK (2) DK0451244T3 (da)
ES (2) ES2125224T3 (da)
FI (1) FI103052B1 (da)
IE (1) IE62771B1 (da)
MA (1) MA22573A1 (da)
NO (1) NO301081B1 (da)
NZ (1) NZ235883A (da)
PT (1) PT95741B (da)
TR (1) TR25991A (da)
WO (1) WO1991006637A1 (da)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287841B1 (en) * 1988-02-11 2001-09-11 Genencor International, Inc. High alkaline serine protease
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
US5352603A (en) * 1989-08-31 1994-10-04 Kali-Chemie Ag Highly alkaline proteases
DK271490D0 (da) * 1990-11-14 1990-11-14 Novo Nordisk As Detergentkomposition
US5482849A (en) * 1990-12-21 1996-01-09 Novo Nordisk A/S Subtilisin mutants
EP0769549A3 (en) * 1990-12-21 1997-05-21 Novo Nordisk A/S Enzyme mutants having a low degree of variation of the molecular charge over a pH range
ES2121014T3 (es) * 1991-05-01 1998-11-16 Novo Nordisk As Enzimas estabilizadas y composiciones detergentes.
US5340735A (en) * 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
DE4224125A1 (de) * 1991-07-27 1993-01-28 Solvay Enzymes Gmbh & Co Kg Verfahren zur verbesserung der stabilitaet von enzymen und stabilisierte enzyme
US6300122B1 (en) 1991-12-20 2001-10-09 Genencor International Method for applying enzyme to non-finished cellulosic-containing fabrics to improve appearance and feel characteristics
EP0571014B1 (en) * 1992-05-18 2004-03-31 Genencor International, Inc. Bacteria producing alkaline proteases, and production of these alkaline proteases
US6251144B1 (en) 1992-06-12 2001-06-26 Genencor International, Inc. Enzymatic compositions and methods for producing stonewashed look on indigo-dyed denim fabric and garments
PT717778E (pt) * 1992-07-17 2008-01-16 Genencor Int Serina proteases resistentes a alcalinidade elevada
US5567601A (en) * 1993-06-01 1996-10-22 University Of Maryland Subtilisin mutants lacking a primary calcium binding site
US5470733A (en) * 1993-06-01 1995-11-28 University Of Maryland Calcium free subtilisin mutants
US6440717B1 (en) * 1993-09-15 2002-08-27 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
ATE361355T1 (de) * 1993-10-14 2007-05-15 Procter & Gamble Proteasehaltige reinigungsmittel
MA23346A1 (fr) * 1993-10-14 1995-04-01 Genencor Int Variantes de la subtilisine
US5932532A (en) * 1993-10-14 1999-08-03 Procter & Gamble Company Bleach compositions comprising protease enzyme
CN1177921C (zh) * 1993-10-14 2004-12-01 普罗格特-甘布尔公司 含有蛋白酶的漂白组合物
US6187579B1 (en) 1993-10-28 2001-02-13 Carlsberg A/S Customized proteases
ES2364774T3 (es) * 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
EP0687733A1 (en) * 1994-06-16 1995-12-20 The Procter & Gamble Company Detergent composition containing wool compatible high alkaline proteases
US5922082A (en) 1994-06-16 1999-07-13 Procter & Gamble Company Detergent composition containing wool compatible high alkaline proteases
JPH10504197A (ja) * 1994-08-11 1998-04-28 ジェネンコア インターナショナル インコーポレーテッド 改善洗浄用組成物
GB9416841D0 (en) 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
US5578136A (en) 1994-08-31 1996-11-26 The Procter & Gamble Company Automatic dishwashing compositions comprising quaternary substituted bleach activators
US6066611A (en) * 1994-10-13 2000-05-23 The Procter & Gamble Company Bleaching compositions comprising protease enzymes
US6455295B1 (en) * 1995-03-08 2002-09-24 The Procter & Gamble Company Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis
IL117350A0 (en) * 1995-03-09 1996-07-23 Procter & Gamble Proteinase k variants having decreased adsorption and increased hydrolysis
US6475765B1 (en) * 1995-03-09 2002-11-05 Procter & Gamble Company Subtilisin DY variants having decreased adsorption and increased hydrolysis
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
US5837517A (en) * 1995-05-05 1998-11-17 Novo Nordisk A/S Protease variants and compositions
US6946280B1 (en) * 1996-03-29 2005-09-20 Genencor International, Inc. Enzyme multimer and process of producing same
US5985627A (en) * 1997-02-28 1999-11-16 Carlsberg Laboratory Modified carboxypeptidase
US6284246B1 (en) 1997-07-30 2001-09-04 The Procter & Gamble Co. Modified polypeptides with high activity and reduced allergenicity
ES2368718T3 (es) 1997-10-23 2011-11-21 Danisco Us Inc. Variantes de subtilisina con múltiples sustituciones.
WO1999031959A2 (en) 1997-12-20 1999-07-01 Genencor International, Inc. Accelerated stability test for granulated protein
CA2313238C (en) 1997-12-20 2009-05-12 Genencor International, Inc. Granule with hydrated barrier material
EP1037968B2 (en) 1997-12-20 2014-02-05 Genencor International, Inc. Matrix granule
AU2005299A (en) 1997-12-20 1999-07-12 Genencor International, Inc. Fluidized bed matrix granule
DK1042501T3 (da) 1997-12-24 2007-08-13 Genencor Int Fremgangsmåde til analyse af vaskeevnen af et enzym
US6936249B1 (en) * 1998-04-15 2005-08-30 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
US6642011B2 (en) * 1998-04-15 2003-11-04 Genencor International, Inc. Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
EP2284272B1 (en) 1998-06-10 2014-08-13 Novozymes A/S Mannanases
US6831053B1 (en) 1998-10-23 2004-12-14 The Procter & Gamble Company Bleaching compositions comprising multiply-substituted protease variants
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
ATE291081T1 (de) 1998-10-27 2005-04-15 Genencor Int Matrixgranulat
WO2000029534A1 (en) 1998-11-13 2000-05-25 Genencor International, Inc. Fluidized bed low density granule
US6579841B1 (en) 1998-12-18 2003-06-17 Genencor International, Inc. Variant EGIII-like cellulase compositions
DK1149151T3 (da) 1999-01-08 2006-07-31 Genencor Int Sammensætninger med lav densitet og partikulære dele, der indbefatter dem
ATE312162T1 (de) 1999-10-15 2005-12-15 Genencor Int Proteinhaltige körnchen und granulatformulierungen
CA2406607C (en) * 2000-04-26 2011-08-02 Land O'lakes, Inc. A method of treating soy proteins and a soy protein product produced by this method
AU2001280968A1 (en) * 2000-07-31 2002-02-13 Menzel, Rolf Compositions and methods for directed gene assembly
US6635465B1 (en) 2000-08-04 2003-10-21 Genencor International, Inc. Mutant EGIII cellulase, DNA encoding such EGIII compositions and methods for obtaining same
US6623949B1 (en) * 2000-08-04 2003-09-23 Genencor International, Inc. Variant EGIII-like cellulase compositions
US7303907B2 (en) * 2001-01-08 2007-12-04 Health Protection Agency Degradation and detection of TSE infectivity
EP1241112A3 (en) 2001-03-15 2003-02-26 The Procter & Gamble Company Flexible multiple compartment pouch
PL210859B1 (pl) * 2001-03-23 2012-03-30 Genencor Int Odmiana subtylizyny zawierająca zmieniony epitop limfocytów T, kwas nukleinowy kodujący tę odmianę subtylizyny, wektor ekspresyjny i komórka gospodarza zawierająca kwas nukleinowy oraz kompozycje zawierające tę odmianę subtylizyny
US8076113B2 (en) 2001-04-02 2011-12-13 Danisco Us Inc. Method for producing granules with reduced dust potential comprising an antifoam agent
ES2295359T3 (es) 2001-06-22 2008-04-16 Genencor International, Inc. Granulos de alta resistencia al impacto.
US7157416B2 (en) * 2001-07-20 2007-01-02 Genencor International, Inc. Stabilization of enzymes
DE10153792A1 (de) 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
DE10162728A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10162727A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14391) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
DE10163884A1 (de) 2001-12-22 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus sp. (DSM 14392) und Wasch- und Reinigungsmittel enthaltend diese neue Alkalische Protease
JP2005514026A (ja) * 2001-12-31 2005-05-19 ジェネンコー・インターナショナル・インク 免疫反応の変化を生じるプロテアーゼ、ならびにその製造および利用方法
US7332320B2 (en) * 2001-12-31 2008-02-19 Genencor International, Inc. Protease producing an altered immunogenic response and methods of making and using the same
ATE450606T1 (de) * 2002-01-16 2009-12-15 Genencor Int Mehrfachsubstituierte proteasevarianten
CA2472723C (en) 2002-01-16 2013-12-17 Genencor International, Inc. Multiply-substituted protease variants
CN101575635A (zh) * 2002-02-26 2009-11-11 金克克国际有限公司 免疫原性减弱的枯草杆菌蛋白酶Carlsberg蛋白
ATE457352T1 (de) * 2002-02-26 2010-02-15 Genencor Int Subtilisin-carlsberg-proteine mit verminderter immunogenität
US7361731B2 (en) 2002-05-20 2008-04-22 Genencor International, Inc. Peptide derivatives, and their use for the synthesis of silicon-based composite materials
BRPI0313080B1 (pt) * 2002-07-30 2018-03-13 Danisco Us Inc. Produto de limpeza, seus método de produção e uso
JP5376747B2 (ja) * 2002-10-02 2013-12-25 カタリスト バイオサイエンシーズ， インコーポレイテッド 改変された特異性を有するプロテアーゼを作製する方法およびスクリーニングする方法
EP2500423B1 (en) 2003-02-26 2015-06-17 Danisco US Inc. Amylases producing an altered immunogenic response and methods of making and using the same
US20070025974A1 (en) * 2003-02-26 2007-02-01 Hardings Fiona A Amylases producing an altered immunogenic response and methods of making and using the same
DE10360805A1 (de) 2003-12-23 2005-07-28 Henkel Kgaa Neue Alkalische Protease und Wasch- und Reinigungsmittel, enthaltend diese neue Alkalische Protease
DE102004019751A1 (de) 2004-04-23 2005-11-17 Henkel Kgaa Neue Alkalische Proteasen und Wasch- und Reinigungsmittel, enthaltend diese neuen Alkalischen Proteasen
WO2005119259A2 (en) * 2004-04-26 2005-12-15 Genencor International, Inc. Population based prediction methods for immune response determinations and methods for verifying immunological response data
WO2005116180A1 (en) 2004-05-17 2005-12-08 The Procter & Gamble Company Bleaching composition comprising a carbohydrate oxidase
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
EP3061461A1 (en) 2004-10-29 2016-08-31 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
US7686892B2 (en) 2004-11-19 2010-03-30 The Procter & Gamble Company Whiteness perception compositions
US9321873B2 (en) 2005-07-21 2016-04-26 Akzo Nobel N.V. Hybrid copolymer compositions for personal care applications
WO2007038570A1 (en) 2005-09-27 2007-04-05 The Procter & Gamble Company Microcapsule and method of producing same
GB0603775D0 (en) * 2006-02-24 2006-04-05 Health Prot Agency Infectivity assay
EP2007506B1 (en) 2006-03-31 2014-03-19 Danisco US Inc. Tangential flow filtration apparatuses, systems, and processes for the separation of compounds
DE102007029643A1 (de) 2006-09-08 2009-01-15 Henkel Ag & Co. Kgaa Reinigungsmittel
KR101570546B1 (ko) 2007-09-12 2015-11-19 다니스코 유에스 인크. 내부 오염 제어에 의한 여과
CA2714751C (en) 2008-02-14 2020-05-05 Danisco Us Inc. Small enzyme-containing granules
US8153574B2 (en) 2009-03-18 2012-04-10 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene polyol acetal derivatives and detersive enzymes
US8293697B2 (en) 2009-03-18 2012-10-23 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene sorbitol acetal derivatives
WO2010138347A1 (en) 2009-05-26 2010-12-02 The Procter & Gamble Company Aqueous liquid composition for pre-treating soiled dishware
US20110009307A1 (en) 2009-07-09 2011-01-13 Alan Thomas Brooker Laundry Detergent Composition Comprising Low Level of Sulphate
WO2011005623A1 (en) 2009-07-09 2011-01-13 The Procter & Gamble Company Laundry detergent composition comprising low level of bleach
CN102652175B (zh) 2009-12-09 2016-02-10 宝洁公司 织物和家居护理产品
DE102010063457A1 (de) * 2010-12-17 2012-06-21 Henkel Ag & Co. Kgaa Lagerstabiles flüssiges Wasch- oder Reinigungsmittel enthaltend Protease und Cellulase
US8841246B2 (en) 2011-08-05 2014-09-23 Ecolab Usa Inc. Cleaning composition containing a polysaccharide hybrid polymer composition and methods of improving drainage
US8679366B2 (en) 2011-08-05 2014-03-25 Ecolab Usa Inc. Cleaning composition containing a polysaccharide graft polymer composition and methods of controlling hard water scale
US8853144B2 (en) 2011-08-05 2014-10-07 Ecolab Usa Inc. Cleaning composition containing a polysaccharide graft polymer composition and methods of improving drainage
US8636918B2 (en) 2011-08-05 2014-01-28 Ecolab Usa Inc. Cleaning composition containing a polysaccharide hybrid polymer composition and methods of controlling hard water scale
JP2014532792A (ja) 2011-11-04 2014-12-08 アクゾ ノーベル ケミカルズ インターナショナル ベスローテン フエンノートシャップＡｋｚｏ Ｎｏｂｅｌ Ｃｈｅｍｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｂ．Ｖ． グラフト樹状コポリマー及びそれを製造する方法
MX2014005094A (es) 2011-11-04 2014-08-08 Akzo Nobel Chemicals Int Bv Copolimeros de dendrita hibridos, composiciones de los mismos y metodos para producirlos.
US10087401B2 (en) 2012-03-16 2018-10-02 Monosol, Llc Water soluble compositions incorporating enzymes, and method of making same
US9394092B2 (en) 2012-04-16 2016-07-19 Monosol, Llc Powdered pouch and method of making same
US8945314B2 (en) 2012-07-30 2015-02-03 Ecolab Usa Inc. Biodegradable stability binding agent for a solid detergent
CN113105950A (zh) 2012-10-04 2021-07-13 艺康美国股份有限公司 用于洗衣和其他硬表面清洁的预浸泡工艺
US9365805B2 (en) 2014-05-15 2016-06-14 Ecolab Usa Inc. Bio-based pot and pan pre-soak
EP3878960A1 (en) 2014-07-04 2021-09-15 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2016001450A2 (en) 2014-07-04 2016-01-07 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3174446B1 (en) 2014-08-01 2019-01-30 Ecolab USA Inc. A method of manual surface cleaning using cleaning textiles and of washing said cleaning textiles
EP3075832B1 (en) 2015-03-30 2021-04-14 Dalli-Werke GmbH & Co. KG Manganese-amino acid compounds in cleaning compositions
EP3205393A1 (en) 2016-02-12 2017-08-16 Basf Se Process for preparation of microcapsules
EP3205392A1 (en) 2016-02-12 2017-08-16 Basf Se Microcapsules and process for preparation of microcapsules
WO2017182295A1 (en) 2016-04-18 2017-10-26 Basf Se Liquid cleaning compositions
WO2017213168A1 (ja) * 2016-06-09 2017-12-14 花王株式会社 変異アルカリプロテアーゼ
RU2019106488A (ru) 2016-08-08 2020-09-14 Басф Се Жидкая композиция для стирки
US10577571B2 (en) 2016-11-08 2020-03-03 Ecolab Usa Inc. Non-aqueous cleaner for vegetable oil soils
BR112019010622A2 (pt) 2016-12-01 2019-10-22 Basf Se composição, métodos para preparação da composição, para remover manchas e para limpeza, microcápsula, e, uso de pentano-1,2-diol.
WO2019105780A1 (en) 2017-11-29 2019-06-06 Basf Se Compositions, their manufacture and use
CN107937372B (zh) * 2017-12-19 2020-03-24 江南大学 一种耐酸性提高的纳豆激酶
WO2019238761A1 (en) 2018-06-15 2019-12-19 Basf Se Water soluble multilayer films containing wash active chemicals and enzymes
WO2020030623A1 (en) 2018-08-10 2020-02-13 Basf Se Packaging unit comprising a detergent composition containing an enzyme and at least one chelating agent
BR112021005954A2 (pt) 2018-10-05 2021-06-29 Basf Se preparação enzimática, processo para produzir uma preparação enzimática estável, métodos para reduzir perda de atividade lipolítica de pelo menos uma lipase, para preparar uma formulação de detergente, para remover manchas e para aumentar a estabilidade de armazenagem de uma formulação de detergente líquido, usos de um composto e da preparação enzimática, e, formulação de detergente.
BR112021006317A2 (pt) 2018-10-05 2021-07-06 Basf Se preparação de enzima, processo para preparar uma preparação de enzima estável, métodos para reduzir perda da atividade amiolítica, de preparação de uma formulação detergente, para remover manchas sensíveis à amilase e para aumentar a estabilidade no armazenamento de uma formulação detergente líquida, usos de um composto e da preparação de enzima, e, formulação detergente
EP3677676A1 (en) 2019-01-03 2020-07-08 Basf Se Compounds stabilizing amylases in liquids
BR112021005412A2 (pt) 2018-10-05 2021-06-15 Basf Se preparação de enzima, processo para fabricar uma preparação de enzima estável, métodos para reduzir a perda da atividade proteolítica, para preparação de uma formulação detergente, para remover manchas e para aumentar a estabilidade na armazenagem de uma formulação detergente líquida, usos de um composto e da preparação de enzima, e, formulação detergente
WO2020104231A1 (en) 2018-11-19 2020-05-28 Basf Se Powders and granules containing a chelating agent and an enzyme
US11492572B2 (en) 2019-12-06 2022-11-08 Alene Candles LLC Effervescing compositions and tablets for treating toilets
WO2020229480A1 (en) 2019-05-14 2020-11-19 Basf Se Compounds stabilizing hydrolases in liquids
US11873465B2 (en) 2019-08-14 2024-01-16 Ecolab Usa Inc. Methods of cleaning and soil release of highly oil absorbing substrates employing optimized extended chain nonionic surfactants
EP4045625A1 (en) 2019-10-18 2022-08-24 Basf Se Storage-stable hydrolase containing liquids
WO2021115912A1 (en) 2019-12-09 2021-06-17 Basf Se Formulations comprising a hydrophobically modified polyethyleneimine and one or more enzymes
MX2022009968A (es) 2020-02-14 2022-09-19 Basf Se Variantes de mananasa.
EP4176031A1 (en) 2020-07-06 2023-05-10 Ecolab USA Inc. Peg-modified castor oil based compositions for microemulsifying and removing multiple oily soils
CN116075583A (zh) 2020-07-06 2023-05-05 埃科莱布美国股份有限公司 包含烷基硅氧烷和水溶助剂/增溶剂的组合的发泡混合醇/水组合物
JP2023534927A (ja) 2020-07-06 2023-08-15 エコラボ ユーエスエー インコーポレイティド 構造化アルコキシル化シロキサンを含む起泡性アルコール／水混合組成物
WO2022008732A1 (en) 2020-07-10 2022-01-13 Basf Se Enhancing the activity of antimicrobial preservatives
US20240247209A1 (en) 2021-05-18 2024-07-25 Nouryon Chemicals International B.V. Polyester polyquats in cleaning applications
WO2022243533A1 (en) 2021-05-20 2022-11-24 Nouryon Chemicals International B.V. Manufactured polymers having altered oligosaccharide or polysaccharide functionality or narrowed oligosaccharide distribution, processes for preparing them, compositions containing them, and methods of using them
US20240287409A1 (en) 2021-06-30 2024-08-29 Nouryon Chemicals International B.V. Chelate-amphoteric surfactant liquid concentrates and use thereof in cleaning applications
WO2023057367A1 (en) 2021-10-08 2023-04-13 Unilever Ip Holdings B.V. Laundry composition
PE20251535A1 (es) 2022-05-14 2025-06-05 Novozymes As Composiciones y metodos para prevenir, tratar, suprimir y/o eliminar infecciones e infestaciones fitopatogenas
US20240026248A1 (en) 2022-07-20 2024-01-25 Ecolab Usa Inc. Novel nonionic extended surfactants, compositions and methods of use thereof
WO2024256175A1 (en) 2023-06-13 2024-12-19 Basf Se Stabilized cleaning compositions comprising edds and enzymes and their use
WO2025031865A1 (en) 2023-08-08 2025-02-13 Basf Se Improved bacillus cell with inactivated metalloprotease
WO2025093368A1 (en) 2023-11-02 2025-05-08 Basf Se Enzyme stabilization in compositions containing a protease inhibitor

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261868A (en) 1979-08-08 1981-04-14 Lever Brothers Company Stabilized enzymatic liquid detergent composition containing a polyalkanolamine and a boron compound
US4404128A (en) 1981-05-29 1983-09-13 The Procter & Gamble Company Enzyme detergent composition
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
NZ208612A (en) * 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
US5013657A (en) 1988-04-12 1991-05-07 Bryan Philip N Subtilisin mutations
US4990452A (en) 1986-02-12 1991-02-05 Genex Corporation Combining mutations for stabilization of subtilisin
DE3750916T2 (de) 1986-04-30 1995-06-01 Genencor Int Mutante einer nicht menschlichen Carbonyl-Hydrolase, für diese kodierende DNS-Sequenzen und Vektoren und durch diese Vektoren transformierte Wirte.
ES2134186T3 (es) 1987-02-27 1999-10-01 Genencor Int Clonaje molecular y expresion de genes que codifican enzimas proteoliticas.
US4914031A (en) * 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
AU3063389A (en) 1988-01-08 1989-08-01 Dpz Deutsches Primatenzentrum Gesellschaft M.B.H. Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions
CN1056187C (zh) † 1988-02-11 2000-09-06 金克克国际有限公司 新的蛋白水解酶及其在洗涤剂中的应用

Also Published As

Publication number Publication date
ES2125224T3 (es) 1999-03-01
US5185258A (en) 1993-02-09
TR25991A (tr) 1993-11-01
CA2044630A1 (en) 1991-05-01
IE62771B1 (en) 1995-02-22
AU6634190A (en) 1991-05-31
DE69034195D1 (de) 2005-07-21
EP0451244B1 (en) 1998-12-23
CA2044630C (en) 2000-05-30
NZ235883A (en) 1992-09-25
FI913166A0 (fi) 1991-06-28
AU633376B2 (en) 1993-01-28
PT95741A (pt) 1991-09-13
DK0775749T3 (da) 2005-09-12
JP3335623B2 (ja) 2002-10-21
DE69034195T2 (de) 2006-03-23
NO912567D0 (no) 1991-06-28
EP0775749A1 (en) 1997-05-28
ATE297997T1 (de) 2005-07-15
NO301081B1 (no) 1997-09-08
AR244339A1 (es) 1993-10-29
EP0451244B9 (en) 2005-01-26
MA22573A1 (fr) 1993-04-01
DE69032852D1 (de) 1999-02-04
WO1991006637A1 (en) 1991-05-16
FI103052B (fi) 1999-04-15
ES2242963T3 (es) 2005-11-16
FI103052B1 (fi) 1999-04-15
IE903905A1 (en) 1991-05-08
ATE174961T1 (de) 1999-01-15
DE69034195T3 (de) 2009-10-22
KR970004938B1 (ko) 1997-04-10
NO912567L (no) 1991-06-28
CN1052897A (zh) 1991-07-10
PT95741B (pt) 1997-10-31
EP0775749B1 (en) 2005-06-15
BR9006993A (pt) 1991-11-26
DK0451244T3 (da) 1999-08-23
ES2242963T5 (es) 2009-08-27
EP0775749B2 (en) 2009-04-01
EP0451244A4 (en) 1992-06-03
JPH04505263A (ja) 1992-09-17
DE69032852T2 (de) 1999-05-20
EP0451244A1 (en) 1991-10-16

Similar Documents

Publication Publication Date Title
DK0775749T4 (da) Subtilisinmutanter
BR9000014A (pt) Classificaodr
ATA149789A (de) Schienenrad
DK56289D0 (da) Subtilisinmutanter
KR910007175U (ko) 캔
ATA293489A (de) Schibob
SE8900937D0 (sv) Plantaetning
BR6900735U (pt) Rotacesta
BR6901354U (pt) Mosquetao
BR6900847U (pt) Tele-alarme
BR6900732U (pt) Reoviscosimetro
BR6901431U (pt) Bate-pula
BR6901912U (pt) Fiodentalizador
BR6900607U (pt) Mini-cone
BR6900454U (pt) Espositor
BR6900207U (pt) Presilha-abracadeira
BR6901802U (pt) Picador-triturador
ATA152989A (de) Skistock
BR6902498U (pt) Varal giratorio
BR6902005U (pt) Vira-pista
BR6902208U (pt) Set-light
BR6902267U (pt) Grosalixa
BR6901807U (pt) Fulao
SE8901010D0 (sv) Hetluftejektor
BR6901774U (pt) Negatoscopio unimaden