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DK0766668T3 - Fremgangsmåde til fremstilling af vandfrie og hydratformer af som antihistaminer anvendelige piperidinderivater, polymorfer og pseudo-morfer deraf - Google Patents

Fremgangsmåde til fremstilling af vandfrie og hydratformer af som antihistaminer anvendelige piperidinderivater, polymorfer og pseudo-morfer deraf

Info

Publication number
DK0766668T3
DK0766668T3 DK95918278T DK95918278T DK0766668T3 DK 0766668 T3 DK0766668 T3 DK 0766668T3 DK 95918278 T DK95918278 T DK 95918278T DK 95918278 T DK95918278 T DK 95918278T DK 0766668 T3 DK0766668 T3 DK 0766668T3
Authority
DK
Denmark
Prior art keywords
antihistamines
polymorphs
anhydrous
morphs
pseudo
Prior art date
Application number
DK95918278T
Other languages
English (en)
Inventor
Frederick J Mccarty
Daniel R Henton
Susan I Tripp
Jill E Dewitt
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26937420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0766668(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK0766668T3 publication Critical patent/DK0766668T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK95918278T 1994-05-18 1995-04-28 Fremgangsmåde til fremstilling af vandfrie og hydratformer af som antihistaminer anvendelige piperidinderivater, polymorfer og pseudo-morfer deraf DK0766668T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24573194A 1994-05-18 1994-05-18
US41716195A 1995-04-11 1995-04-11
PCT/US1995/004942 WO1995031437A1 (en) 1994-05-18 1995-04-28 Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudormophs thereof

Publications (1)

Publication Number Publication Date
DK0766668T3 true DK0766668T3 (da) 2002-10-28

Family

ID=26937420

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95918278T DK0766668T3 (da) 1994-05-18 1995-04-28 Fremgangsmåde til fremstilling af vandfrie og hydratformer af som antihistaminer anvendelige piperidinderivater, polymorfer og pseudo-morfer deraf

Country Status (17)

Country Link
US (12) US20010014741A1 (da)
EP (3) EP1178041A1 (da)
JP (7) JPH10500134A (da)
CN (3) CN1148849A (da)
AT (1) ATE220667T1 (da)
AU (1) AU693892B2 (da)
CA (3) CA2189007C (da)
DE (1) DE69527429T2 (da)
DK (1) DK0766668T3 (da)
ES (1) ES2176329T3 (da)
FI (1) FI964565A7 (da)
HU (1) HU227676B1 (da)
IL (3) IL113747A (da)
MX (1) MX9605613A (da)
NO (1) NO315319B1 (da)
PT (1) PT766668E (da)
WO (1) WO1995031437A1 (da)

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SK13822003A3 (sk) * 2001-04-09 2004-09-08 Teva Pharmaceutical Industries Ltd. Polymorfné formy chloridu fexofenadínu
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
US7700779B2 (en) * 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
EE200400010A (et) * 2001-06-18 2004-02-16 Dr. Reddy's Laboratories Ltd. 4-[4-[4-(hüdroksüdifenüülmetüül)-1-piperidinüül]-1-hüdroksübutüül]-a,a-dimetüülben seenäädikhappe ja selle hüdrokloriidi uued kristalsed vormid
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US20030158227A1 (en) * 2001-11-08 2003-08-21 Barnaba Krochmal Polymorphs of fexofenadine base
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WO2005102999A2 (en) * 2004-04-26 2005-11-03 Teva Pharmaceutical Industries Ltd. Crystalline forms of fexofenadine hydrochloride and processes for their preparation
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US20060148851A1 (en) * 2004-09-28 2006-07-06 Shlomit Wizel Fexofenadine crystal form and processes for its preparation thereof
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US20080095843A1 (en) * 2006-07-11 2008-04-24 Nutalapati Siva R K Controlled-release formulations
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
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WO2010083360A2 (en) * 2009-01-16 2010-07-22 Mutual Pharmaceutical Company, Inc. Controlled-release formulations
JP2013510113A (ja) 2009-11-06 2013-03-21 ビーエーエスエフ ソシエタス・ヨーロピア ４−ヒドロキシ安息香酸及び選択された殺有害生物剤の結晶複合体
US9216955B2 (en) 2010-06-15 2015-12-22 Chemelectiva S.R.L. Polymorphic form of Fexofenadine hydrochloride, intermediates and process for its preparation
IT1400965B1 (it) * 2010-06-15 2013-07-05 Dipharma Francis Srl Polimorfi di fexofenadina
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Also Published As

Publication number Publication date
IL134917A0 (en) 2001-05-20
US20010014741A1 (en) 2001-08-16
CN1623985A (zh) 2005-06-08
HK1098467A1 (en) 2007-07-20
CA2189007C (en) 2004-03-02
US20010025106A1 (en) 2001-09-27
US20020193603A1 (en) 2002-12-19
CA2585705C (en) 2012-04-17
HUT76134A (en) 1997-06-30
US20040014976A1 (en) 2004-01-22
EP1178041A1 (en) 2002-02-06
US7138524B2 (en) 2006-11-21
IL113747A0 (en) 1995-08-31
EP0766668B1 (en) 2002-07-17
JPH10500134A (ja) 1998-01-06
FI964565A0 (fi) 1996-11-14
EP0766668A1 (en) 1997-04-09
US20020193601A1 (en) 2002-12-19
JP4503909B2 (ja) 2010-07-14
FI964565L (fi) 1996-11-14
US7666881B2 (en) 2010-02-23
JP2002308850A (ja) 2002-10-23
US20010012896A1 (en) 2001-08-09
US7662835B2 (en) 2010-02-16
US20080167469A1 (en) 2008-07-10
HU227676B1 (en) 2011-11-28
IL113747A (en) 2001-05-20
US20070021462A1 (en) 2007-01-25
JP4503907B2 (ja) 2010-07-14
FI964565A7 (fi) 1996-11-14
IL134917A (en) 2001-07-24
DE69527429D1 (de) 2002-08-22
US20020193600A1 (en) 2002-12-19
ATE220667T1 (de) 2002-08-15
JP4503908B2 (ja) 2010-07-14
MX9605613A (es) 1998-05-31
CN1907967A (zh) 2007-02-07
DE69527429T2 (de) 2003-03-20
NO964859D0 (no) 1996-11-15
AU693892B2 (en) 1998-07-09
PT766668E (pt) 2002-11-29
CA2449419C (en) 2011-09-06
US20080167471A1 (en) 2008-07-10
NO964859L (no) 1996-11-15
CA2189007A1 (en) 1995-11-23
CN1907967B (zh) 2012-07-04
US20030045721A1 (en) 2003-03-06
US7135571B2 (en) 2006-11-14
JP2002255935A (ja) 2002-09-11
WO1995031437A1 (en) 1995-11-23
CN1148849A (zh) 1997-04-30
JP2002255936A (ja) 2002-09-11
CA2449419A1 (en) 1995-11-23
CA2585705A1 (en) 1995-11-23
NO315319B1 (no) 2003-08-18
JP2002316978A (ja) 2002-10-31
US20070021461A1 (en) 2007-01-25
AU2426595A (en) 1995-12-05
EP2354125A1 (en) 2011-08-10
JP2010120969A (ja) 2010-06-03
ES2176329T3 (es) 2002-12-01
HU9603167D0 (en) 1997-01-28
JP2002308849A (ja) 2002-10-23
HK1137742A1 (en) 2010-08-06

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