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DK0763100T3 - Fremgangsmåde til rensning af Clostridium difficile-texin og fremstilling af monospecifkke antistoffer - Google Patents

Fremgangsmåde til rensning af Clostridium difficile-texin og fremstilling af monospecifkke antistoffer

Info

Publication number
DK0763100T3
DK0763100T3 DK95942617T DK95942617T DK0763100T3 DK 0763100 T3 DK0763100 T3 DK 0763100T3 DK 95942617 T DK95942617 T DK 95942617T DK 95942617 T DK95942617 T DK 95942617T DK 0763100 T3 DK0763100 T3 DK 0763100T3
Authority
DK
Denmark
Prior art keywords
texin
purification
preparation
clostridium difficile
monospecific antibodies
Prior art date
Application number
DK95942617T
Other languages
English (en)
Inventor
John W Deutsch
Original Assignee
Lee Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lee Lab Inc filed Critical Lee Lab Inc
Application granted granted Critical
Publication of DK0763100T3 publication Critical patent/DK0763100T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK95942617T 1995-03-31 1995-12-08 Fremgangsmåde til rensning af Clostridium difficile-texin og fremstilling af monospecifkke antistoffer DK0763100T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/414,640 US5610023A (en) 1995-03-31 1995-03-31 Method of purification of clostridium difficile toxin A and production of mono-specific antibodies
PCT/US1995/016150 WO1996030494A1 (en) 1995-03-31 1995-12-08 Method of purification of clostridium difficile toxin a and production of mono-specific antibodies

Publications (1)

Publication Number Publication Date
DK0763100T3 true DK0763100T3 (da) 2008-09-15

Family

ID=23642303

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95942617T DK0763100T3 (da) 1995-03-31 1995-12-08 Fremgangsmåde til rensning af Clostridium difficile-texin og fremstilling af monospecifkke antistoffer

Country Status (8)

Country Link
US (1) US5610023A (da)
EP (1) EP0763100B1 (da)
JP (1) JP2001505525A (da)
AU (1) AU4378296A (da)
CA (1) CA2191774A1 (da)
DE (1) DE69535754D1 (da)
DK (1) DK0763100T3 (da)
WO (1) WO1996030494A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179611B2 (en) 1997-02-10 2007-02-20 Bd Lee Laboratories Mono-specific polyclonal antibodies and methods for detecting Clostridium difficile Toxin A
US5965375A (en) * 1997-04-04 1999-10-12 Biosite Diagnostics Diagnostic tests and kits for Clostridium difficile
AU746859B2 (en) * 1997-06-20 2002-05-02 Imperial College Of Science, Technology And Medicine Immonogenic fragments of toxin a of clostridium difficile
US6290946B1 (en) * 1999-05-13 2001-09-18 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders and antibacterial agents
US6270755B1 (en) 1999-05-13 2001-08-07 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders
CA2314494A1 (en) 2000-05-02 2001-11-02 Geltex Pharmaceuticals, Inc. Anionic polymers as species specific antibacterial agents
CA2492211A1 (en) * 2002-07-22 2004-01-29 Genzyme Corporation Poly(potassium and sodium styrene sulfonate), its manufacture and its uses
US20060078534A1 (en) * 2004-10-13 2006-04-13 Dominique Charmot Toxin binding compositions
JP2008515996A (ja) * 2004-10-13 2008-05-15 イリプサ， インコーポレイテッド 毒素結合性オリゴ糖および重合体粒子を含有する医薬組成物
CA2714720A1 (en) 2008-02-28 2009-09-03 3M Innovative Properties Company Antibodies to clostridium difficile spores and uses thereof
MX391236B (es) 2011-04-22 2025-03-21 Wyeth Llc Composiciones relacionadas con una toxina de clostridium difficile mutante y sus metodos.
BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
US20160045586A1 (en) * 2013-03-15 2016-02-18 Sanofi Pasteur, Inc. Toxoid, Compositions and Related Methods

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2652636A1 (de) * 1976-11-19 1978-05-24 Hans Uwe Dr Rer Nat Wolf Verfahren zur stabilisierung von proteinen und verwandten verbindungen waehrend ihrer reinigung, isolierung und lagerung
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
US4937201A (en) * 1982-06-10 1990-06-26 Mitsubishi Kasei Corporation Latex reagent for detection of the toxin of clostridium difficile
US4530833A (en) * 1982-09-13 1985-07-23 Wilkins Tracy D Toxins and antibodies of C. difficile
US4533630A (en) * 1982-09-13 1985-08-06 Wilkins Tracy D Toxins and antibodies of C. difficile
US4879218A (en) * 1982-09-13 1989-11-07 Virginia Tech Intellectual Properties, Inc. Antibody for C.difficile
US4689299A (en) * 1982-09-30 1987-08-25 University Of Rochester Human monoclonal antibodies against bacterial toxins
EP0154064A1 (en) * 1984-03-02 1985-09-11 Tracy Dale Wilkins Toxins and antibodies of C. difficile
EP0153519B1 (en) * 1984-03-02 1988-06-01 Tracy Dale Wilkins Toxins and antibodies of c. difficile
US4959457A (en) * 1984-05-31 1990-09-25 Genentech, Inc. Anti-lymphotoxin
US4863852A (en) * 1985-07-03 1989-09-05 Virginia Tech Intellectual Properties, Inc. Method of detecting, isolating and purifying clostridium difficile toxin A and its receptors
US5071759A (en) * 1986-05-30 1991-12-10 The United States Of America As Represented By The Secretary Of The Army Hybridoma cell lines and monoclonal antibodies to clostridum difficile toxins A and B
DK255887D0 (da) * 1987-05-20 1987-05-20 Claus Koch Immunoassay
US5098826A (en) * 1990-03-09 1992-03-24 Virginia Tech Intellectual Properties, Inc. Detection, isolation and purification of Clostridium difficile toxin A with toxin receptors
US5266315A (en) * 1990-05-07 1993-11-30 Kabushiki Kaisha Miyarisan Seibutsu Igaku Kenkyusho Composite for Clostridium difficile diarrhea and pseudomembranous colitis
US5231003A (en) * 1990-05-11 1993-07-27 Cambridge Bioscience Corporation Monoclonal antibodies specific for toxin b of clostridium difficile
US5545721A (en) * 1992-12-21 1996-08-13 Ophidian Pharmaceuticals, Inc. Conjugates for the prevention and treatment of sepsis

Also Published As

Publication number Publication date
EP0763100A1 (en) 1997-03-19
CA2191774A1 (en) 1996-10-03
EP0763100A4 (en) 2001-12-05
EP0763100B1 (en) 2008-05-14
WO1996030494A1 (en) 1996-10-03
DE69535754D1 (de) 2008-06-26
JP2001505525A (ja) 2001-04-24
US5610023A (en) 1997-03-11
AU4378296A (en) 1996-10-16

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