DK0752838T3 - Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol) - Google Patents

Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol)

Info

Publication number: DK0752838T3
Authority: DK; Denmark
Prior art keywords: delta; thc; tetrahydrocannabinol; suppository formulations; stable suppository
Prior art date: 1993-05-21

Application number

DK94917418T

Other languages

English (en)

Inventor

Mahmoud A Elsohly

Original Assignee

Univ Mississippi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-21

Filing date

1994-05-17

Publication date

2003-08-11

1994-05-17 Application filed by Univ Mississippi filed Critical Univ Mississippi

2003-08-11 Application granted granted Critical

2003-08-11 Publication of DK0752838T3 publication Critical patent/DK0752838T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/15—Suppositories

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK94917418T 1993-05-21 1994-05-17 Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol) DK0752838T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/065,117 US5389375A (en)	1993-05-21	1993-05-21	Stable suppository formulations effecting bioavailability of Δ9 -thc
PCT/US1994/005512 WO1994027533A1 (en)	1993-05-21	1994-05-17	Stable suppository formulations effecting biovailability of δ9-thc

Publications (1)

Publication Number	Publication Date
DK0752838T3 true DK0752838T3 (da)	2003-08-11

Family

ID=22060436

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94917418T DK0752838T3 (da)	1993-05-21	1994-05-17	Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol)

Country Status (11)

Country	Link
US (2)	US5389375A (da)
EP (1)	EP0752838B1 (da)
JP (1)	JPH08510741A (da)
KR (1)	KR100354403B1 (da)
AT (1)	ATE237336T1 (da)
CA (1)	CA2163363C (da)
DE (1)	DE69432527T2 (da)
DK (1)	DK0752838T3 (da)
MX (1)	MX9403799A (da)
PL (1)	PL175113B1 (da)
WO (1)	WO1994027533A1 (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6132762A (en) *	1997-05-05	2000-10-17	Cristobal; Walter	Transcutaneous application of marijuana
US5847128A (en) *	1998-05-29	1998-12-08	Virginia Commonwealth University	Water soluble derivatives of cannabinoids
US6008383A (en) *	1998-10-26	1999-12-28	University Of Mississippi	Method of preparing delta-9-tetrahydrocannabinol esters
AU3697200A (en) *	1999-02-04	2000-08-25	New Millennium Pharmaceutical Research, Inc.	Method for enhancement of delivery of thc by the administration of its prodrugs via the nasal route
AU3910700A (en)	1999-03-22	2000-10-09	Immugen Pharmaceuticals, Inc.	Treatment of immune diseases
US6566560B2 (en)	1999-03-22	2003-05-20	Immugen Pharmaceuticals, Inc.	Resorcinolic compounds
US6747058B1 (en)	1999-08-20	2004-06-08	Unimed Pharmaceuticals, Inc.	Stable composition for inhalation therapy comprising delta-9-tetrahydrocannabinol and semiaqueous solvent therefor
US7648696B2 (en) *	1999-08-20	2010-01-19	Unimed Pharmaceuticals, Llc	Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent
WO2002026224A2 (en) *	2000-09-28	2002-04-04	Immugen Pharmaceuticals, Inc.	Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
WO2002026728A2 (en) *	2000-09-28	2002-04-04	Immugen Pharmaceuticals, Inc.	Antiviral methods and compounds
EP1321159A1 (en)	2001-12-21	2003-06-25	CHIESI FARMACEUTICI S.p.A.	Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices
WO2003080043A1 (en) *	2002-03-18	2003-10-02	Immugen Pharmaceuticals, Inc.	Topical formulations of resorcinols and cannibinoids and methods of use
WO2006007734A1 (de) *	2004-07-19	2006-01-26	Cilag Ltd.	Verfahren zur gewinnung von reinem tetrahydrocannabinol
TWI436991B (zh)	2004-11-22	2014-05-11	Euro Celtique Sa	用於純化反-（-）-△９-四氫大麻酚與反-（＋）-△９-四氫大麻酚之方法
EA200701246A1 (ru) *	2004-12-09	2008-06-30	Инсис Терапьютикс, Инк.	Стабильные при комнатной температуре составы дронабинола
TWI366460B (en) *	2005-06-16	2012-06-21	Euro Celtique Sa	Cannabinoid active pharmaceutical ingredient for improved dosage forms
EP2578577A1 (en)	2005-09-29	2013-04-10	Albany Molecular Research, Inc.	Sulfonyl esters of tetrahydrocannabinol and derivatives thereof
CA2659775A1 (en) *	2006-08-04	2008-02-14	Insys Therapeutics Inc.	Aqueous dronabinol formulations
US20080181942A1 (en) *	2006-11-30	2008-07-31	University Of Plymouth	Delta-9-THC compositions and methods for treating symptoms associated with multiple sclerosis
US20080175902A1 (en) *	2006-11-30	2008-07-24	University Of Plymouth	Methods for slowing the progression of multiple sclerosis
US8436051B2 (en) *	2007-06-08	2013-05-07	Aptalis Pharma Canada Inc.	Mesalamine suppository
US8217083B2 (en) *	2007-06-08	2012-07-10	Aptalis Pharma Canada Inc.	Mesalamine suppository
US7541384B2 (en)	2007-06-08	2009-06-02	Axcan Pharma Inc.	Mesalamine suppository
PT2176208E (pt) *	2007-07-30	2015-05-11	Zynerba Pharmaceuticals Inc	Pró-fármacos de canabidiol, composições compreendendo pró- fármacos de canabidiol e métodos de utilização dos mesmos
CA2698752A1 (en) *	2007-08-06	2009-02-12	Insys Therapeutics Inc.	Oral cannabinoid liquid formulations and methods of treatment
SI2215071T1 (sl)	2007-11-30	2015-12-31	Zynerba Pharmaceuticals, Inc.	Predzdravila tetrahidrokanabinola, sestavki, ki obsegajo predzdravila tetrahidrokanabinola in postopki njihove uporabe
JP5518418B2 (ja) *	2008-10-06	2014-06-11	第一三共ヘルスケア株式会社	坐薬製剤組成物
CA2741862C (en) *	2008-10-31	2017-10-17	Mahmoud A. Elsohly	Compositions containing delta-9-thc-amino acid esters and process of preparation
US10092538B2 (en) *	2016-10-21	2018-10-09	Axim Biotechnologies, Inc.	Suppositories comprising cannabinoids
WO2019049142A1 (en)	2017-09-08	2019-03-14	Scicann Therapeutics Inc.	COMPOSITIONS COMPRISING CANNABINOID AND SPILANTHOL
WO2019195943A1 (en) *	2018-04-13	2019-10-17	Urban Juve Provisions Inc.	Cannabis root extract, method of manufacture, method of use
US10695301B2 (en) *	2018-09-04	2020-06-30	Babak Ghalili	Veterinary cannabinoid and menthol compositions and methods
AU2021230540A1 (en)	2020-03-04	2022-10-13	Pleopharma, L.L.C.	Methods and compositions for treating cannabis use disorder and mitigating cannabinoid withdrawal
US12029718B2 (en)	2021-11-09	2024-07-09	Cct Sciences, Llc	Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3728360A (en) *	1971-08-31	1973-04-17	Little Inc A	Ester derivatives of tetrahydrocannabinol
US4933363A (en) *	1988-08-16	1990-06-12	Elsohly Mahmoud A	Method for effecting systemic delivery of delta-9-tetrahydrocannabinol

1993
- 1993-05-21 US US08/065,117 patent/US5389375A/en not_active Expired - Lifetime
1994
- 1994-05-17 PL PL94311706A patent/PL175113B1/pl not_active IP Right Cessation
- 1994-05-17 WO PCT/US1994/005512 patent/WO1994027533A1/en not_active Ceased
- 1994-05-17 JP JP7500759A patent/JPH08510741A/ja active Pending
- 1994-05-17 EP EP94917418A patent/EP0752838B1/en not_active Expired - Lifetime
- 1994-05-17 DE DE69432527T patent/DE69432527T2/de not_active Expired - Fee Related
- 1994-05-17 DK DK94917418T patent/DK0752838T3/da active
- 1994-05-17 CA CA002163363A patent/CA2163363C/en not_active Expired - Fee Related
- 1994-05-17 KR KR1019950705085A patent/KR100354403B1/ko not_active Expired - Fee Related
- 1994-05-17 AT AT94917418T patent/ATE237336T1/de not_active IP Right Cessation
- 1994-05-23 MX MX9403799A patent/MX9403799A/es unknown
1995
- 1995-02-02 US US08/382,500 patent/US5508037A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
MX9403799A (es)	1997-02-28
CA2163363C (en)	2007-01-30
KR100354403B1 (ko)	2002-12-26
ATE237336T1 (de)	2003-05-15
DE69432527T2 (de)	2004-04-08
EP0752838A1 (en)	1997-01-15
US5389375A (en)	1995-02-14
CA2163363A1 (en)	1994-12-08
DE69432527D1 (de)	2003-05-22
EP0752838A4 (en)	1996-05-30
AU6915194A (en)	1994-12-20
EP0752838B1 (en)	2003-04-16
AU689110B2 (en)	1998-03-26
US5508037A (en)	1996-04-16
WO1994027533A1 (en)	1994-12-08
JPH08510741A (ja)	1996-11-12
PL311706A1 (en)	1996-03-04
PL175113B1 (pl)	1998-11-30

Publication	Publication Date	Title
DK0752838T3 (da)	2003-08-11	Stabile suppositorieformuleringer af delta-9-THC (tetrahydrocannabinol)
DK0812198T3 (da)	2002-03-18	Stabilisering af prostaglandinpræparater
DK0656774T3 (da)	1997-06-16	Kosmetiske og dermatologiske lysbeskyttelsesformuleringer med et indhold af thioler og/eller thiolderivater
FI943749L (fi)	1995-02-18	Taksaanijohdannaisten fosfono-oksimetyylieetterit
DE69225965D1 (de)	1998-07-23	Stabile druckempfindliche schrumpflabel-technik
ES2168414T3 (es)	2002-06-16	Formulaciones de retinoides en microesferas porosas de irritacion reducida y estabilidad aumentada.
DE69818672D1 (de)	2003-11-06	Compositionen auf basis von resveratrolderivaten
ES2135347B1 (es)	2000-05-16	Hidroxifeniltriazinas.
DK0650483T3 (da)	2000-03-27	(3R,4R)-Delta6-tetrahydrocannabinol-7-syrer
DK0513387T3 (da)	2000-06-05	Thiazolderivater som inhibitorer af aktivt oxygen
ATE56968T1 (de)	1990-10-15	Substituierte oxo-piperazinyl-triazine und uvlicht stabilisierte zubereitungen.
KR950700554A (ko)	1995-01-16	집적된 광소자들의 정렬방법(alignment of integrated optical components)
DK0679154T3 (da)	1998-03-30	Ny krystallinsk form af en d-vitamininanalog
DK0426949T3 (da)	1994-04-25	Stabilisering af koncentrerede hydrogenperoxidopløsninger
ATE98675T1 (de)	1994-01-15	Wasserstoffperoxid enthaltende stabile bleichmittelzusammensetzungen.
MX9204563A (es)	1993-02-01	Nuevos derivados de la (2-alquil-3-piridil)-metilpiperazina y composicion farmaceutica que los comprende.
DK1216692T3 (da)	2007-06-25	Anvendelse af alpha-CECH i kosmetiske præparater
FI923752A0 (fi)	1992-08-20	Benso(f)kinolinoner.
FI924478A0 (fi)	1992-10-05	24-oxa-derivat i vitamin d-serien
ES2045484T3 (es)	1994-01-16	Nuevos derivados de la vitamina d: aplicaciones terapeuticas y a las dosificaciones de los metabolitos de la vitamina d.
FI945732A0 (fi)	1994-12-05	Vaahtoa hillitsevä koostumus, joka sisältää silikonia ja piidioksidia
PT99503A (pt)	1992-09-30	Processo para a preparacao de novos derivados da n-benzoil-prolina e de composicoes farmaceuticas que os contem
ES2052897T3 (es)	1994-07-16	Nucleosidos didesoxidideshidrocarbociclicos.
DK0460164T3 (da)	1995-04-03	Stabilisering af hydrogenperoxidopløsninger
DE69409758D1 (de)	1998-05-28	Herstellung von Alkyl-Tert-Alkylethern