DK0742211T3 - Pyridazinonderivater - Google Patents
PyridazinonderivaterInfo
- Publication number
- DK0742211T3 DK0742211T3 DK95906505T DK95906505T DK0742211T3 DK 0742211 T3 DK0742211 T3 DK 0742211T3 DK 95906505 T DK95906505 T DK 95906505T DK 95906505 T DK95906505 T DK 95906505T DK 0742211 T3 DK0742211 T3 DK 0742211T3
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen atom
- atom
- alkyl group
- group
- äwherein
- Prior art date
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical compound OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 229940127218 antiplatelet drug Drugs 0.000 abstract 1
- 230000006502 antiplatelets effects Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 abstract 1
- 229940043274 prophylactic drug Drugs 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 229940126585 therapeutic drug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP654194 | 1994-01-25 | ||
| PCT/JP1995/000069 WO1995019969A1 (en) | 1994-01-25 | 1995-01-24 | Pyridazinone derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0742211T3 true DK0742211T3 (da) | 2000-08-14 |
Family
ID=11641211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95906505T DK0742211T3 (da) | 1994-01-25 | 1995-01-24 | Pyridazinonderivater |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US5750523A (da) |
| EP (1) | EP0742211B1 (da) |
| KR (1) | KR100318653B1 (da) |
| CN (1) | CN1049892C (da) |
| AT (1) | ATE192741T1 (da) |
| AU (1) | AU1466395A (da) |
| CA (1) | CA2181901C (da) |
| DE (1) | DE69516849T2 (da) |
| DK (1) | DK0742211T3 (da) |
| ES (1) | ES2147841T3 (da) |
| FI (1) | FI112214B (da) |
| HU (1) | HU223963B1 (da) |
| NO (1) | NO307965B1 (da) |
| PT (1) | PT742211E (da) |
| TW (1) | TW420665B (da) |
| WO (1) | WO1995019969A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL110040A (en) * | 1993-06-29 | 2000-07-16 | Nissan Chemical Ind Ltd | Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them |
| TW482675B (en) * | 1997-01-31 | 2002-04-11 | Green Cross Corp | Compositions for oral administration containing pyridazinone compounds technical field of the invention |
| KR100573376B1 (ko) | 1998-09-01 | 2006-04-25 | 닛산 가가쿠 고교 가부시키 가이샤 | 척추관 협착증 치료제 |
| CZ20012020A3 (cs) * | 1998-12-07 | 2001-10-17 | Nissan Chemical Industries, Ltd. | Činidlo pro léčbu erektilní dysfunkce |
| ES2195785B1 (es) * | 2002-05-16 | 2005-03-16 | Almirall Prodesfarma, S.A. | Nuevos derivados de piridazin-3(2h)-ona. |
| US20070161642A1 (en) * | 2004-02-09 | 2007-07-12 | Nissan Chemical Industries Ltd. | Drug for inhibiting vascular intimal hyperplasia |
| KR100854584B1 (ko) | 2006-03-20 | 2008-08-27 | 주식회사 엘지생명과학 | 피리다지논, 피리미돈 또는 피리돈 구조를 포함하는선택적인 트롬빈 억제제 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0641455B2 (ja) * | 1984-12-10 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| JPH0641454B2 (ja) * | 1985-02-27 | 1994-06-01 | 日産化学工業株式会社 | ピリダジノン誘導体 |
| US4892947A (en) * | 1985-04-27 | 1990-01-09 | Nissan Chemical Industries Ltd. | 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it |
| US4978665A (en) * | 1987-01-20 | 1990-12-18 | Nissan Chemical Industries Ltd. | 3(2H)pyridazinone, and antagonistic agent against SRS-A containing it |
| JPH02256668A (ja) * | 1988-12-20 | 1990-10-17 | Nissan Chem Ind Ltd | ピリダジノン誘導体 |
| DK0482208T3 (da) * | 1990-04-25 | 2000-09-18 | Nissan Chemical Ind Ltd | Pyridazinonderivat |
| JPH0517357A (ja) * | 1991-07-05 | 1993-01-26 | Nissan Chem Ind Ltd | 血小板減少療法剤 |
| IL110040A (en) * | 1993-06-29 | 2000-07-16 | Nissan Chemical Ind Ltd | Pyridazinone derivatives their preparation and pharmaceutical compositions comprising them |
| AU681694B2 (en) * | 1993-09-06 | 1997-09-04 | Ishihara Sangyo Kaisha Ltd. | Pyridazinone derivatives or their salts, processes for theirproduction, and anti-shock agents containing them |
-
1995
- 1995-01-24 WO PCT/JP1995/000069 patent/WO1995019969A1/ja not_active Ceased
- 1995-01-24 AU AU14663/95A patent/AU1466395A/en not_active Abandoned
- 1995-01-24 EP EP95906505A patent/EP0742211B1/en not_active Expired - Lifetime
- 1995-01-24 DK DK95906505T patent/DK0742211T3/da active
- 1995-01-24 CA CA002181901A patent/CA2181901C/en not_active Expired - Lifetime
- 1995-01-24 AT AT95906505T patent/ATE192741T1/de active
- 1995-01-24 CN CN95191304A patent/CN1049892C/zh not_active Expired - Lifetime
- 1995-01-24 US US08/676,227 patent/US5750523A/en not_active Expired - Lifetime
- 1995-01-24 DE DE69516849T patent/DE69516849T2/de not_active Expired - Lifetime
- 1995-01-24 KR KR1019960703941A patent/KR100318653B1/ko not_active Expired - Lifetime
- 1995-01-24 PT PT95906505T patent/PT742211E/pt unknown
- 1995-01-24 HU HU9602021A patent/HU223963B1/hu active IP Right Grant
- 1995-01-24 ES ES95906505T patent/ES2147841T3/es not_active Expired - Lifetime
- 1995-01-27 TW TW084100797A patent/TW420665B/zh not_active IP Right Cessation
-
1996
- 1996-07-24 NO NO963095A patent/NO307965B1/no not_active IP Right Cessation
- 1996-07-24 FI FI962957A patent/FI112214B/fi not_active IP Right Cessation
-
1997
- 1997-09-24 US US08/936,600 patent/US5856327A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5856327A (en) | 1999-01-05 |
| PT742211E (pt) | 2000-10-31 |
| NO307965B1 (no) | 2000-06-26 |
| AU1466395A (en) | 1995-08-08 |
| US5750523A (en) | 1998-05-12 |
| KR100318653B1 (ko) | 2002-04-22 |
| CA2181901A1 (en) | 1995-07-27 |
| ATE192741T1 (de) | 2000-05-15 |
| EP0742211B1 (en) | 2000-05-10 |
| CN1138852A (zh) | 1996-12-25 |
| CN1049892C (zh) | 2000-03-01 |
| HUT74742A (en) | 1997-02-28 |
| FI962957A0 (fi) | 1996-07-24 |
| CA2181901C (en) | 2005-09-13 |
| TW420665B (en) | 2001-02-01 |
| FI962957L (fi) | 1996-07-24 |
| NO963095D0 (no) | 1996-07-24 |
| EP0742211A4 (en) | 1997-03-26 |
| EP0742211A1 (en) | 1996-11-13 |
| ES2147841T3 (es) | 2000-10-01 |
| FI112214B (fi) | 2003-11-14 |
| NO963095L (no) | 1996-09-24 |
| DE69516849T2 (de) | 2000-10-12 |
| WO1995019969A1 (en) | 1995-07-27 |
| HU223963B1 (hu) | 2005-03-29 |
| DE69516849D1 (de) | 2000-06-15 |
| HU9602021D0 (en) | 1996-09-30 |
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