DK0619839T3 - Nye polypeptider til fremme af cellebinding - Google Patents
Nye polypeptider til fremme af cellebindingInfo
- Publication number
- DK0619839T3 DK0619839T3 DK93900897T DK93900897T DK0619839T3 DK 0619839 T3 DK0619839 T3 DK 0619839T3 DK 93900897 T DK93900897 T DK 93900897T DK 93900897 T DK93900897 T DK 93900897T DK 0619839 T3 DK0619839 T3 DK 0619839T3
- Authority
- DK
- Denmark
- Prior art keywords
- fibronectin
- cells
- binding site
- fusion proteins
- cell binding
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 102000005962 receptors Human genes 0.000 abstract 3
- 108020003175 receptors Proteins 0.000 abstract 3
- 108010067306 Fibronectins Proteins 0.000 abstract 2
- 102000016359 Fibronectins Human genes 0.000 abstract 2
- 101001027128 Homo sapiens Fibronectin Proteins 0.000 abstract 2
- 102000037865 fusion proteins Human genes 0.000 abstract 2
- 108020001507 fusion proteins Proteins 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 101000781681 Protobothrops flavoviridis Disintegrin triflavin Proteins 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 230000021164 cell adhesion Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/24—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/804,224 US5492890A (en) | 1990-12-03 | 1991-12-05 | Polypeptides for promoting cell attachment |
| PCT/US1992/010511 WO1993011229A1 (en) | 1991-12-05 | 1992-12-04 | Novel polypeptides for promoting cell attachment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0619839T3 true DK0619839T3 (da) | 2000-09-18 |
Family
ID=25188472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93900897T DK0619839T3 (da) | 1991-12-05 | 1992-12-04 | Nye polypeptider til fremme af cellebinding |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5492890A (da) |
| EP (1) | EP0619839B1 (da) |
| JP (2) | JP4272257B2 (da) |
| AT (1) | ATE194382T1 (da) |
| AU (1) | AU680607B2 (da) |
| CA (1) | CA2125174C (da) |
| DE (1) | DE69231228T2 (da) |
| DK (1) | DK0619839T3 (da) |
| ES (1) | ES2147558T3 (da) |
| GR (1) | GR3034352T3 (da) |
| PT (1) | PT619839E (da) |
| WO (1) | WO1993011229A1 (da) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770198A (en) * | 1988-05-18 | 1998-06-23 | The Research Foundation Of The State Of New York | Platelet-specific chimeric 7E3 immunoglobulin |
| US6521594B1 (en) | 1990-04-06 | 2003-02-18 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| US6017877A (en) * | 1990-04-06 | 2000-01-25 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| US5672585A (en) * | 1990-04-06 | 1997-09-30 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| US5780303A (en) * | 1990-04-06 | 1998-07-14 | La Jolla Cancer Research Foundation | Method and composition for treating thrombosis |
| US5645815A (en) * | 1991-02-08 | 1997-07-08 | Diatide, Inc. | Radiolabled compounds for thrombus imaging |
| US5629291A (en) * | 1992-01-31 | 1997-05-13 | La Jolla Cancer Research Foundation | Methods of modulating fibronectin extracellular matrix assembly |
| US5968476A (en) * | 1992-05-21 | 1999-10-19 | Diatide, Inc. | Technetium-99m labeled peptides for thrombus imaging |
| US7083979B1 (en) * | 1994-03-25 | 2006-08-01 | Indiana University Foundation | Methods for enhanced retroviral-mediated gene transfer |
| US5763270A (en) * | 1995-06-07 | 1998-06-09 | Genemedicine, Inc. | Plasmid for delivery of nucleic acids to cells and methods of use |
| WO1997011604A1 (en) * | 1995-09-29 | 1997-04-03 | Indiana University Foundation | Methods for enhanced virus-mediated dna transfer using molecules with virus- and cell-binding domains |
| ES2259182T3 (es) | 1995-11-13 | 2006-09-16 | Takara Bio Inc. | Metodo de introduccion de genes en celulas diana por medio de retrovirus. |
| US6242587B1 (en) | 1996-10-02 | 2001-06-05 | The University Of North Carolina At Chapel Hill | DNA molecules encoding a calcium-integrin binding protein |
| US5840514A (en) * | 1996-11-21 | 1998-11-24 | The Regents Of The University Of Michigan | Methods of testing cancer and anticancer drugs |
| US6001965A (en) * | 1996-11-21 | 1999-12-14 | The Regents Of The University Of Michigan | Anticancer compounds and methods |
| US6025150A (en) * | 1996-11-21 | 2000-02-15 | The Regents Of The University Of Michigan | Methods and compositions for wound healing |
| US6331409B1 (en) | 1996-11-21 | 2001-12-18 | The Regents Of The University Of Michigan | Methods and compositions for wound healing |
| WO1998022617A1 (en) * | 1996-11-21 | 1998-05-28 | The Regents Of The University Of Michigan | Invasion-inducing agents and invasion-inhibitors for use in wound healing and cancer |
| AU3192299A (en) * | 1998-03-18 | 1999-10-11 | Wake Forest University | Improved implantable biomaterials, compositions and methods for their preparation and uses thereof |
| AU5785999A (en) * | 1998-08-25 | 2000-03-14 | University Of Washington | Streptavidin mutants having secondary functional domains |
| US8460367B2 (en) * | 2000-03-15 | 2013-06-11 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US20050271701A1 (en) * | 2000-03-15 | 2005-12-08 | Orbus Medical Technologies, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US8088060B2 (en) * | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
| US9522217B2 (en) * | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
| CA2400319C (en) * | 2000-03-15 | 2008-09-16 | Orbus Medical Technologies Inc. | Coating that promotes endothelial cell adherence |
| US20160287708A9 (en) * | 2000-03-15 | 2016-10-06 | Orbusneich Medical, Inc. | Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device |
| US7374906B2 (en) | 2000-11-08 | 2008-05-20 | Surface Logix, Inc. | Biological assays using gradients formed in microfluidic systems |
| US6844184B2 (en) * | 2000-11-08 | 2005-01-18 | Surface Logix, Inc. | Device for arraying biomolecules and for monitoring cell motility in real-time |
| US7033821B2 (en) * | 2000-11-08 | 2006-04-25 | Surface Logix, Inc. | Device for monitoring cell motility in real-time |
| US7033819B2 (en) | 2000-11-08 | 2006-04-25 | Surface Logix, Inc. | System for monitoring cell motility in real-time |
| US6864065B2 (en) * | 2000-11-08 | 2005-03-08 | Surface Logix, Inc. | Assays for monitoring cell motility in real-time |
| US7326563B2 (en) | 2000-11-08 | 2008-02-05 | Surface Logix, Inc. | Device and method for monitoring leukocyte migration |
| US6699665B1 (en) * | 2000-11-08 | 2004-03-02 | Surface Logix, Inc. | Multiple array system for integrating bioarrays |
| US6893851B2 (en) | 2000-11-08 | 2005-05-17 | Surface Logix, Inc. | Method for arraying biomolecules and for monitoring cell motility in real-time |
| JP4590117B2 (ja) * | 2001-02-21 | 2010-12-01 | 森永製菓株式会社 | 免疫測定試薬 |
| US20030082148A1 (en) * | 2001-10-31 | 2003-05-01 | Florian Ludwig | Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo |
| US20060078535A1 (en) * | 2004-10-13 | 2006-04-13 | The Regents Of The University Of Michigan | Anticancer compounds and methods |
| US8921516B2 (en) * | 2010-12-08 | 2014-12-30 | Corning Incorporated | Synthetic, defined fibronectin mimetic peptides and surfaces modified with the same |
| CN111454350B (zh) * | 2020-06-01 | 2020-12-29 | 广东丸美生物技术股份有限公司 | 一种重组纤连蛋白突变体及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4792525A (en) * | 1982-08-04 | 1988-12-20 | La Jolla Cancer Research Foundation | Tetrapeptide |
| US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
| EP0114887B1 (en) * | 1982-08-04 | 1990-11-28 | La Jolla Cancer Research Foundation | Polypeptide |
| US4980279A (en) * | 1986-04-15 | 1990-12-25 | Scripps Clinic And Research Foundation | Cellular fibronectin: polypeptides, anti-polypeptide antibodies and assay methods |
| US5019646A (en) * | 1987-08-25 | 1991-05-28 | Regents Of The University Of Minnesota | Polypeptides with fibronectin activity |
| JPH0829098B2 (ja) * | 1988-01-05 | 1996-03-27 | 寳酒造株式会社 | 細胞接着活性ポリペプチド |
| US5773574A (en) * | 1990-12-03 | 1998-06-30 | The Scripps Research Institute | Polypeptides for promoting cell attachment |
| AU1515392A (en) * | 1991-04-26 | 1992-10-29 | Mark Rossi | Method and apparatus for cane trash removal |
| US5453489A (en) * | 1992-01-31 | 1995-09-26 | La Jolla Cancer Research Foundation | Polypeptide fragments of fibronectin which can modulate extracellular matrix assembly |
-
1991
- 1991-12-05 US US07/804,224 patent/US5492890A/en not_active Expired - Lifetime
-
1992
- 1992-12-04 EP EP93900897A patent/EP0619839B1/en not_active Expired - Lifetime
- 1992-12-04 PT PT93900897T patent/PT619839E/pt unknown
- 1992-12-04 CA CA002125174A patent/CA2125174C/en not_active Expired - Lifetime
- 1992-12-04 WO PCT/US1992/010511 patent/WO1993011229A1/en not_active Ceased
- 1992-12-04 JP JP51037493A patent/JP4272257B2/ja not_active Expired - Lifetime
- 1992-12-04 DE DE69231228T patent/DE69231228T2/de not_active Expired - Lifetime
- 1992-12-04 AT AT93900897T patent/ATE194382T1/de active
- 1992-12-04 AU AU32408/93A patent/AU680607B2/en not_active Expired
- 1992-12-04 DK DK93900897T patent/DK0619839T3/da active
- 1992-12-04 ES ES93900897T patent/ES2147558T3/es not_active Expired - Lifetime
-
2000
- 2000-09-06 GR GR20000402040T patent/GR3034352T3/el unknown
-
2007
- 2007-07-25 JP JP2007193288A patent/JP2007312788A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| CA2125174A1 (en) | 1993-06-10 |
| JPH07504812A (ja) | 1995-06-01 |
| AU3240893A (en) | 1993-06-28 |
| CA2125174C (en) | 2007-04-10 |
| ATE194382T1 (de) | 2000-07-15 |
| EP0619839B1 (en) | 2000-07-05 |
| EP0619839A4 (en) | 1995-09-20 |
| WO1993011229A1 (en) | 1993-06-10 |
| DE69231228D1 (de) | 2000-08-10 |
| ES2147558T3 (es) | 2000-09-16 |
| US5492890A (en) | 1996-02-20 |
| JP2007312788A (ja) | 2007-12-06 |
| EP0619839A1 (en) | 1994-10-19 |
| GR3034352T3 (en) | 2000-12-29 |
| DE69231228T2 (de) | 2000-11-30 |
| JP4272257B2 (ja) | 2009-06-03 |
| AU680607B2 (en) | 1997-08-07 |
| PT619839E (pt) | 2000-10-31 |
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