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DK0686195T3 - Fremgangsmåde og system til forhöjet produktion af kommercielt vigtige exoproteiner i grampositive bakterier - Google Patents

Fremgangsmåde og system til forhöjet produktion af kommercielt vigtige exoproteiner i grampositive bakterier

Info

Publication number
DK0686195T3
DK0686195T3 DK94908357T DK94908357T DK0686195T3 DK 0686195 T3 DK0686195 T3 DK 0686195T3 DK 94908357 T DK94908357 T DK 94908357T DK 94908357 T DK94908357 T DK 94908357T DK 0686195 T3 DK0686195 T3 DK 0686195T3
Authority
DK
Denmark
Prior art keywords
exoproteins
gram
pct
positive bacteria
increased production
Prior art date
Application number
DK94908357T
Other languages
English (en)
Inventor
Vesa Kontinen
Matti Sarvas
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of DK0686195T3 publication Critical patent/DK0686195T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK94908357T 1993-02-26 1994-02-25 Fremgangsmåde og system til forhöjet produktion af kommercielt vigtige exoproteiner i grampositive bakterier DK0686195T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2415493A 1993-02-26 1993-02-26

Publications (1)

Publication Number Publication Date
DK0686195T3 true DK0686195T3 (da) 2006-11-27

Family

ID=21819138

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94908357T DK0686195T3 (da) 1993-02-26 1994-02-25 Fremgangsmåde og system til forhöjet produktion af kommercielt vigtige exoproteiner i grampositive bakterier

Country Status (9)

Country Link
US (1) US5780261A (da)
EP (1) EP0686195B1 (da)
JP (2) JPH08507207A (da)
CN (1) CN1080307C (da)
AT (1) ATE335083T1 (da)
AU (1) AU6142694A (da)
DE (1) DE69434807T2 (da)
DK (1) DK0686195T3 (da)
WO (1) WO1994019471A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
KR0169913B1 (ko) 1996-03-14 1999-01-15 김은영 신균주 바실러스속 ds11과 이로부터 생산되는 신규 파이타아제
US5945278A (en) * 1996-07-08 1999-08-31 The Finnish National Public Health Institute Method and system for enhanced production of commercially important exoproteins in gram-positive bacteria
US5919999A (en) * 1996-11-14 1999-07-06 Queen's University At Kingston Enhanced transport with a plastid membrane transport protein
US20030157642A1 (en) 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
ATE252641T1 (de) * 1997-07-15 2003-11-15 Genencor Int Erhöhung der proteinproduktion in gram-positiven mikroorganismen
CA2296689C (en) * 1997-07-16 2014-04-01 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
AU759776C (en) * 1997-12-05 2004-05-20 Regents Of The University Of California, The An over-expressing homologous antigen vaccine and a method of making the same
EP1038959A1 (en) 1999-03-17 2000-09-27 Aventis Behring Gesellschaft mit beschränkter Haftung Factor VIII without B-domain, comprising one or more insertions of a truncated intron I of factor IX
US20050000666A1 (en) * 2003-05-06 2005-01-06 Novozymes A/S Use of hemicellulase composition in mechanical pulp production
EP1694846B1 (en) 2003-12-10 2014-10-01 Novozymes A/S A cell with improved secretion mediated by mrga protein or homologue
US20060121042A1 (en) 2004-10-27 2006-06-08 Medimmune, Inc. Modulation of antibody specificity by tailoring the affinity to cognate antigens
JP5226958B2 (ja) * 2007-02-22 2013-07-03 花王株式会社 組換え微生物
WO2012127001A1 (en) 2011-03-23 2012-09-27 Novozymes A/S Methods for producing secreted polypeptides
WO2012127002A1 (en) 2011-03-23 2012-09-27 Novozymes A/S Sweet-tasting polypeptide from gram-positive bacteria
EP2546272A1 (en) 2011-07-15 2013-01-16 Ticona GmbH Process for producing oxymethylene polymers
CN104845923B (zh) * 2014-02-14 2018-03-23 中国科学院微生物研究所 生产l‑组氨酸的方法及其专用重组菌
US11667922B2 (en) 2018-03-26 2023-06-06 Novozymes A/S Fungal chaperone proteins
EP3918086A1 (en) 2019-01-30 2021-12-08 Novozymes A/S Cognate foldase co-expression
WO2020182552A1 (en) 2019-03-08 2020-09-17 Novozymes A/S Means and methods for improving protease expression
CN118556120A (zh) 2021-11-16 2024-08-27 丹尼斯科美国公司 用于增强芽孢杆菌属细胞中蛋白质产生的组合物和方法
CN120500529A (zh) 2023-01-05 2025-08-15 巴斯夫欧洲公司 折叠酶用于改善分泌分子的异源表达的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952508A (en) * 1980-03-10 1990-08-28 Cetus Corporation Method and vector organism for controlled accumulation of cloned heterologous gene products in Bacillus subtilis
US4711843A (en) * 1980-12-31 1987-12-08 Cetus Corporation Method and vector organism for controlled accumulation of cloned heterologous gene products in Bacillus subtilis
US4994379A (en) * 1983-03-09 1991-02-19 Cetus Corporation Modified signal peptides
US5017477A (en) * 1985-10-25 1991-05-21 Biotechnica International, Inc. Enhancing DNA sequencies derived from the sacQ gene
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US4965197A (en) * 1987-06-12 1990-10-23 Massachusetts Institute Of Technology Coryneform expression and secretion system

Also Published As

Publication number Publication date
JP2004350691A (ja) 2004-12-16
AU6142694A (en) 1994-09-14
DE69434807D1 (de) 2006-09-14
EP0686195B1 (en) 2006-08-02
WO1994019471A1 (en) 1994-09-01
CN1080307C (zh) 2002-03-06
US5780261A (en) 1998-07-14
JPH08507207A (ja) 1996-08-06
ATE335083T1 (de) 2006-08-15
CN1120853A (zh) 1996-04-17
EP0686195A1 (en) 1995-12-13
DE69434807T2 (de) 2007-03-29
JP4202985B2 (ja) 2008-12-24

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